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[192268_at] homeobox; tissue factor pathway inhibitor

Description C02F12.5 /REP_DB=WormBase Gene ID /WP=CE27051 /GB=AAK39138.1 /SUBMIT=ST.LOUIS /CHR=X /FEA=Sanger Annotation /DEF=homeobox; tissue factor pathway inhibitor
Cluster 6grp_total > 84      4grp_total > 50      6grp_total_sub > Hat      6grp_rule_based > S4      

Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 112
1 2 3 4 range
A 64.1
(-3)
A 		113.4
(3)
P 		79
(-1.2)
A 		65.5
(-2.8)
A 		49
B 73.3
(-1.5)
A 		112.4
(0.6)
P 		157.8
(3)
A 		46.3
(-3)
A 		112
C 82.9
(-0.9)
A 		131.2
(3)
P 		64.5
(-2.3)
A 		56.1
(-3)
A 		75
avr 73.4
(-1.3) 		119
(3) 		100.4
(1.2) 		56
(-3) 		63

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 272
1 2 3 4 5 6 range
A 29.1
(-3)
A 		74
(-2)
P 		133.1
(-0.7)
P 		260.9
(2.1)
P 		301.3
(3)
P 		220.1
(1.2)
A 		272
B 46.5
(-3)
A 		81.3
(-1.8)
A 		147.3
(0.6)
P 		215.6
(3)
P 		179.7
(1.7)
P 		171.2
(1.4)
P 		169
C 47.1
(-3)
A 		90.2
(-0.4)
P 		96
(-0)
P 		144.9
(3)
A 		127.1
(1.9)
P 		129.1
(2)
P 		98
avr 40.9
(-3) 		81.8
(-1.5) 		125.5
(0.1) 		207.1
(3) 		202.7
(2.8) 		173.5
(1.8) 		166
No Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 28
1 2 3 4 range
A 23.3
(2.5)
A 		24.6
(3)
P 		20.6
(1.4)
A 		9.6
(-3)
A 		15
B 23.4
(0)
A 		27.8
(1)
P 		36.6
(3)
A 		9.9
(-3)
A 		27
C 27.4
(0.8)
A 		37.7
(3)
P 		22.5
(-0.2)
A 		9.5
(-3)
A 		28
avr 24.7
(1.4) 		30
(3) 		26.6
(2) 		9.7
(-3) 		20

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 86
1 2 3 4 5 6 range
A 5.4
(-3)
A 		26.3
(-1.5)
P 		29
(-1.3)
P 		66.2
(1.3)
P 		90.9
(3)
P 		53.6
(0.4)
A 		86
B 16.2
(-3)
A 		27.1
(-1.8)
A 		35.8
(-0.9)
P 		57.1
(1.3)
P 		73
(3)
P 		63.8
(2)
P 		57
C 17.4
(-3)
A 		27.5
(-0.7)
P 		24.4
(-1.4)
P 		29.1
(-0.3)
A 		41.1
(2.5)
P 		43.2
(3)
P 		26
avr 13
(-3) 		27
(-1.5) 		29.7
(-1.2) 		50.8
(1.1) 		68.3
(3) 		53.5
(1.4) 		55
NetAffx Links Cluster Members
Consensus/Exemplar
GeneChip Array Information
Probe Set ID 192268_at
GeneChip Array C. elegans Genome Array
Organism Common Name Nematode
Probe Design Information
Transcript ID(Array Design) affy.Ce.18325
Sequence Type Exemplar sequence
Representative Public ID C02F12.5 NCBI
Target Description C02F12.5 /REP_DB=WormBase Gene ID /WP=CE27051 /GB=AAK39138.1 /SUBMIT=ST.LOUIS /CHR=X /FEA=Sanger Annotation /DEF=homeobox; tissue factor pathway inhibitor
Cluster Evidence This cluster is supported by a Sanger Annotation.
Annotation Method Description
Annotation Description This probe set was annotated using the Matching Probes based pipeline to a RefSeq identifier using 1 transcript(s).
Annotation Grade This is a grade A annotation.
Annotation Transcript Cluster (# of Matching Probes) NM_076231(11)
Transcript Assignments
Representative
Transcript		 Description Matching Probes Related Probesets by Grade
NM_076231 NCBI Caenorhabditis elegans C02F12.5 (C02F12.5) mRNA, complete cds. 11/11 None
GENEFINDER00000032668 ENSEMBL cdna:GeneFinder chromosome:CEL140:X:3669591:3673613:-1 10/11 None
SNAP00000032659 ENSEMBL cdna:SNAP chromosome:CEL140:X:3670605:3673613:-1 9/11 None
C02F12.5 ENSEMBL cdna:known chromosome:CEL140:X:3670427:3673675:-1 gene:C02F12.5 11/11 None
Annotation Notes
There are no noteworthy cross hybridizing mRNAs found for this probe set.
Genomic Alignment of Consensus/Exemplar Sequence
Assembly Wormbase March 2004
Alignment(s)
Position Identity Coverage Cytoband
chrX:3670999-3673676(-) 100.0 100.0
Public Domain and Genome References
Gene Title homeobox; tissue factor pathway inhibitor
Ensembl C02F12.5
Entrez Gene 180656 Entrez gene
SwissProt Q11101 EMBL-EBI
WormBase CE27051 Wormbase
Functional Annotations
Gene Ontology
GO Biological Process (view graph)
ID Description Evidence Links
6355 regulation of transcription, DNA-dependent inferred from electronic annotation QuickGO AmiGO
GO Cellular Component (view graph)
ID Description Evidence Links
5634 nucleus inferred from electronic annotation QuickGO AmiGO
GO Molecular Function (view graph)
ID Description Evidence Links
3677 DNA binding inferred from electronic annotation QuickGO AmiGO
3700 transcription factor activity inferred from electronic annotation QuickGO AmiGO
4867 serine-type endopeptidase inhibitor activity inferred from electronic annotation QuickGO AmiGO
Protein Similarities
Method ID Description E-Value
blast AAK39138 Hypothetical protein C02F12.5 [Caenorhabditis elegans] ref|NP_508632.1| C02F12.5 [Caenorhabditis elegans] sp|Q11101|YL15_CAEEL Hypothetical homeobox protein C02F12.5 in chromosome X 1.0E-156
blast T34078 hypothetical protein C02F12.5 - Caenorhabditis elegans 1.0E-118
blast AAK39138 Hypothetical protein C02F12.5 [Caenorhabditis elegans] ref|NP_508632.1| C02F12.5 [Caenorhabditis elegans] sp|Q11101|YL15_CAEEL Hypothetical homeobox protein C02F12.5 in chromosome X 3.0E-98
blast AAK39138 Hypothetical protein C02F12.5 [Caenorhabditis elegans] ref|NP_508632.1| C02F12.5 [Caenorhabditis elegans] sp|Q11101|YL15_CAEEL Hypothetical homeobox protein C02F12.5 in chromosome X 5.0E-98
blast T34078 hypothetical protein C02F12.5 - Caenorhabditis elegans 8.0E-98
blast T34078 hypothetical protein C02F12.5 - Caenorhabditis elegans 8.0E-75
blast CAE68464 Hypothetical protein CBG14258 [Caenorhabditis briggsae] 3.0E-73
Protein Domains
Database ID Description E-Value
scop a.4.1.Homeodomain All alpha proteins; DNA/RNA-binding 3-helical bundle; Homeodomain-like; Homeodomain 8.99999984060745E-23
scop a.4.1.Homeodomain All alpha proteins; DNA/RNA-binding 3-helical bundle; Homeodomain-like; Homeodomain 7.00000015651189E-23
scop a.4.1.Homeodomain All alpha proteins; DNA/RNA-binding 3-helical bundle; Homeodomain-like; Homeodomain 3.99999999927983E-23
Pfam IPR001356 EMBL-EBI Homeobox 1.5E-24
Pfam IPR001356 EMBL-EBI Homeobox 2.6E-25
Pfam IPR002223 EMBL-EBI Pancreatic trypsin inhibitor (Kunitz) 1.7E-4
Pfam IPR001356 EMBL-EBI Homeobox 1.5E-24
Sequence
Target Sequence 
>C. ELEGANS:192268_AT
attaagaacatcaaaccgccaccgaaaaggagcaatcgaccgactaaaagaacaactttc
acatcggagcaggtcacacttttggagttggaatttgcaaagaatgaatacatctgcaaa
gaccgacgcggcgagttggctcaaacaattgaactcactgaatgtcaagtgaagacctgg
tttcagaaccggagaactaaaaaacgaagttctgagttgaaatttggaactgcgtgctct
gaaaacaaaacttctacaaagtggtattatgattccaaattattgttttgctatccgtac
aagtatttgggatgtggagaaggatcaaactcatttgaatccaacgagaactgccttgaa
tcttgtaaaccagctgaccaattttcatgcggc

BLASTn GenBank NR
Probe Info
Probe Sequence(5'-3') Probe X Probe Y Probe Interrogation
Position 		Strandedness
ATTAAGAACATCAAACCGCCACCGA 705 11 97 Antisense
GAACAACTTTCACATCGGAGCAGGT 139 353 146 Antisense
CGGAGCAGGTCACACTTTTGGAGTT 404 241 161 Antisense
GAATACATCTGCAAAGACCGACGCG 303 327 202 Antisense
AAAGACCGACGCGGCGAGTTGGCTC 338 123 214 Antisense
GAAGACCTGGTTTCAGAACCGGAGA 630 331 267 Antisense
GAAATTTGGAACTGCGTGCTCTGAA 700 361 315 Antisense
AAATTATTGTTTTGCTATCCGTACA 601 115 373 Antisense
ATTTGAATCCAACGAGAACTGCCTT 138 17 429 Antisense
GAACTGCCTTGAATCTTGTAAACCA 518 347 444 Antisense
ACCAGCTGACCAATTTTCATGCGGC 35 87 465 Antisense
Sequence Source Affymetrix Proprietary Database