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[192243_at] T-complex protein

Description T05C12.7 /REP_DB=WormBase Gene ID /WP=CE02319 /GEN=cct-1 /TR=SW:P41988 /GB=CAA91308.1 /SUBMIT=HINXTON /CHR=2 /FEA=Sanger Annotation /DEF=T-complex protein
Cluster 6grp_highest_10_10 > 61      6grp_high1_10_10 > 16      4grp_highest_8_8 > 13      4grp_high_8_8 > 31      6grp_highest_nonorm > 01      6grp_total > 16      4grp_total > 24      6grp_highest_sub > De      6grp_cgc > 22      6grp_high1_sub > De      6grp_cgc_sub > De      6grp_total_sub > Decrease      6grp_rule_based > S1      4grp_rule_based > L4      

Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 1297
1 2 3 4 range
A 2408.1
(-2.9)
P 		2385.6
(-3)
P 		3132
(1)
P 		3503.2
(3)
P 		1118
B 2226.4
(-3)
P 		3056.7
(0.8)
P 		3147
(1.3)
P 		3523.7
(3)
P 		1297
C 2341.3
(-3)
P 		3126.1
(3)
P 		3048.3
(2.4)
P 		3095.8
(2.8)
P 		785
avr 2325.3
(-3) 		2856.1
(0) 		3109.1
(1.5) 		3374.2
(3) 		1049

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 1565
1 2 3 4 5 6 range
A 2893
(3)
P 		2389.4
(1)
P 		1803.2
(-1.2)
P 		1491.8
(-2.5)
P 		1350.6
(-3)
P 		1861.7
(-1)
P 		1542
B 2873.6
(3)
P 		2320.5
(0.5)
P 		1613.6
(-2.8)
P 		1613.4
(-2.8)
P 		1567.5
(-3)
P 		1595.8
(-2.9)
P 		1306
C 2886.9
(3)
P 		2122.6
(0.1)
P 		1980.9
(-0.5)
P 		1327.8
(-3)
P 		1715.7
(-1.5)
P 		1340.9
(-2.9)
P 		1559
avr 2884.5
(3) 		2277.5
(0.4) 		1799.2
(-1.6) 		1477.7
(-3) 		1544.6
(-2.7) 		1599.5
(-2.5) 		1407
No Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 550
1 2 3 4 range
A 876.8
(3)
P 		517.9
(-2.9)
P 		818.8
(2)
P 		512.8
(-3)
P 		364
B 710
(-3)
P 		754.9
(3)
P 		729.2
(-0.4)
P 		750.9
(2.5)
P 		45
C 775
(-0.2)
P 		898.8
(1.2)
P 		1062.4
(3)
P 		522
(-3)
P 		540
avr 787.3
(1.2) 		723.9
(-0.2) 		870.1
(3) 		595.2
(-3) 		275

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 803
1 2 3 4 5 6 range
A 533.3
(-1)
P 		849.8
(3)
P 		392.7
(-2.8)
P 		378.4
(-3)
P 		407.6
(-2.6)
P 		453.3
(-2)
P 		471
B 999.9
(3)
P 		772.4
(0.8)
P 		391.8
(-3)
P 		427.3
(-2.6)
P 		636.9
(-0.6)
P 		595.1
(-1)
P 		608
C 1070
(3)
P 		647.7
(-0.2)
P 		504.2
(-1.2)
P 		267
(-3)
P 		555.2
(-0.8)
P 		448.9
(-1.6)
P 		803
avr 867.7
(3) 		756.6
(1.7) 		429.6
(-2.2) 		357.6
(-3) 		533.2
(-0.9) 		499.1
(-1.3) 		510
NetAffx Links Cluster Members
Consensus/Exemplar
GeneChip Array Information
Probe Set ID 192243_at
GeneChip Array C. elegans Genome Array
Organism Common Name Nematode
Probe Design Information
Transcript ID(Array Design) affy.Ce.3942
Sequence Type Exemplar sequence
Representative Public ID T05C12.7 NCBI
Target Description T05C12.7 /REP_DB=WormBase Gene ID /WP=CE02319 /GEN=cct-1 /TR=SW:P41988 /GB=CAA91308.1 /SUBMIT=HINXTON /CHR=2 /FEA=Sanger Annotation /DEF=T-complex protein
Cluster Evidence This cluster is supported by a Sanger Annotation.
Annotation Method Description
Annotation Description This probe set was annotated using the Matching Probes based pipeline to a RefSeq identifier using 1 transcript(s).
Annotation Grade This is a grade A annotation.
Annotation Transcript Cluster (# of Matching Probes) NM_063321(11)
Transcript Assignments
Representative
Transcript		 Description Matching Probes Related Probesets by Grade
NM_063321 NCBI Caenorhabditis elegans Chaperonin Containing TCP-1 family member (cct-1) (cct-1) mRNA, complete cds. 11/11 A 
SNAP00000002114 ENSEMBL cdna:SNAP chromosome:CEL140:II:8185367:8187308:1 11/11 None
GENEFINDER00000002124 ENSEMBL cdna:GeneFinder chromosome:CEL140:II:8185367:8187308:1 11/11 None
T05C12.7.4 ENSEMBL cdna:known chromosome:CEL140:II:8185357:8187516:1 gene:T05C12.7 11/11 None
T05C12.7.3 ENSEMBL cdna:known chromosome:CEL140:II:8185359:8187516:1 gene:T05C12.7 11/11 A 
T05C12.7.2 ENSEMBL cdna:known chromosome:CEL140:II:8185360:8187524:1 gene:T05C12.7 11/11 A 
T05C12.7.1 ENSEMBL cdna:known chromosome:CEL140:II:8185364:8187524:1 gene:T05C12.7 11/11 A 
Annotation Notes
There are no noteworthy cross hybridizing mRNAs found for this probe set.
Genomic Alignment of Consensus/Exemplar Sequence
Assembly Wormbase March 2004
Alignment(s)
Position Identity Coverage Cytoband
chrII:8185363-8187305(+) 100.0 100.0
Public Domain and Genome References
Gene Title T-complex protein
Gene Symbol cct-1
Ensembl T05C12.7
Entrez Gene 174318 Entrez gene
SwissProt P41988 EMBL-EBI
WormBase CE02319 Wormbase
Functional Annotations
Ortholog
ID Title Organism
ATH1-121501:257125_AT T-complex protein 1 alpha subunit / TCP-1-alpha / chaperonin (CCT1) at
CANINE:1583327_AT similar to T-complex protein 1, alpha subunit (TCP-1-alpha) (CCT-alpha) cfa
CANINE_2:CFA.21272.1.S1_S_AT similar to T-complex protein 1, alpha subunit (TCP-1-alpha) (CCT-alpha) cfa
CANINE_2:CFA.21272.2.S1_AT similar to T-complex protein 1, alpha subunit (TCP-1-alpha) (CCT-alpha) cfa
CANINE_2:CFA.970.1.S1_S_AT similar to T-complex protein 1, alpha subunit (TCP-1-alpha) (CCT-alpha) cfa
DROSOPHILA_2:1627638_S_AT Tcp1-like dm
DROSGENOME1:143374_AT Tcp1-like dm
CHICKEN:GGA.5262.1.S1_S_AT t-complex 1 gga
HG-U95AV2:34791_AT t-complex 1 hs
HUGENEFL:X52882_AT t-complex 1 hs
HG-U133A:208778_S_AT t-complex 1 hs
HG-U133_PLUS_2:208778_S_AT t-complex 1 hs
HG-U133A_2:208778_S_AT t-complex 1 hs
U133_X3P:G12653758_3P_S_AT t-complex 1 hs
U133_X3P:HS.278544.2.A1_3P_S_AT t-complex 1 hs
HG-U133A_2:222010_AT t-complex 1 hs
HG-U133_PLUS_2:222010_AT t-complex 1 hs
HG-U133A:222010_AT t-complex 1 hs
HG-U133A_2:222011_S_AT t-complex 1 hs
HG-FOCUS:222011_S_AT t-complex 1 hs
HG-U133_PLUS_2:222011_S_AT t-complex 1 hs
HG-U133A:222011_S_AT t-complex 1 hs
MOE430A:1448122_AT t-complex protein 1 mm
MOUSE430_2:1448122_AT t-complex protein 1 mm
MOUSE430A_2:1448122_AT t-complex protein 1 mm
MU11KSUBA:D90344_S_AT t-complex protein 1 mm
MG-U74AV2:94218_AT t-complex protein 1 mm
MG-U74AV2:162443_AT t-complex protein 1 mm
MU19KSUBA:TC19010_AT T-complex protein 1, mRNA (cDNA clone MGC:6094 IMAGE:3599670) mm
MU19KSUBA:TC24361_AT T-complex protein 1, mRNA (cDNA clone MGC:6094 IMAGE:3599670) mm
MU19KSUBC:TC39454_AT T-complex protein 1, mRNA (cDNA clone MGC:6094 IMAGE:3599670) mm
MU19KSUBC:TC39454_G_AT T-complex protein 1, mRNA (cDNA clone MGC:6094 IMAGE:3599670) mm
RG-U34A:RC_AA875054_AT t-complex protein 1 rn
RAE230A:1368049_AT t-complex protein 1 rn
RAT230_2:1368049_AT t-complex protein 1 rn
YEAST_2:1779318_AT Alpha subunit of chaperonin-containing T-complex, which mediates protein folding in the cytosol; involved in maintenance of actin cytoskeleton; homolog to Drosophila melanogaster and mouse tailless complex polypeptide Sc
Protein Similarities
Method ID Description E-Value
blast CAA91308 Hypothetical protein T05C12.7 [Caenorhabditis elegans] ref|NP_495722.1| Chaperonin Containing TCP-1 family member (cct-1) [Caenorhabditis elegans] 0.0
blast P41988 T-complex protein 1, alpha subunit (TCP-1-alpha) (CCT-alpha) gb|AAB05072.1| CCT-1 0.0
blast CAE57713 Hypothetical protein CBG00721 [Caenorhabditis briggsae] 0.0
Protein Domains
Database ID Description E-Value
Pfam IPR002423 EMBL-EBI Chaperonin Cpn60/TCP-1 1.0E-126
Sequence
Target Sequence 
>C. ELEGANS:192243_AT
agtgacgacgagctcattctcatcaagggaccgaaatctcgtactgccagcagcattatc
ctccgtggagcgaacgatgtgatgctcgatgaaatggagagatcggttcacgactcactc
tgtgttgttcgtagagttctggaaagcaagaaacttgtggctggaggaggtgctgttgag
acttctctcagtcttttccttgaaacttatgcacaaaccttgtcttctcgcgagcagctt
gctgttgctgaattcgcttcagcgcttctcatcattccgaaggttttggcaagcaatgct
gcaagagattctactgatttagtgacaaaactccgcgcgtaccactccaaagctcaattg
atcccacaacttcaacacctcaagtgggctggtttggatctcgaaga

BLASTn GenBank NR
Probe Info
Probe Sequence(5'-3') Probe X Probe Y Probe Interrogation
Position 		Strandedness
AGTGACGACGAGCTCATTCTCATCA 106 61 1090 Antisense
CGAAATCTCGTACTGCCAGCAGCAT 292 253 1121 Antisense
GGAGAGATCGGTTCACGACTCACTC 57 519 1185 Antisense
CGACTCACTCTGTGTTGTTCGTAGA 611 249 1200 Antisense
AGGAGGTGCTGTTGAGACTTCTCTC 674 55 1254 Antisense
TTCTCTCAGTCTTTTCCTTGAAACT 194 691 1272 Antisense
TTATGCACAAACCTTGTCTTCTCGC 467 681 1296 Antisense
CTCGCGAGCAGCTTGCTGTTGCTGA 387 233 1316 Antisense
AGCGCTTCTCATCATTCCGAAGGTT 705 81 1350 Antisense
AAGCTCAATTGATCCCACAACTTCA 114 151 1439 Antisense
AGTGGGCTGGTTTGGATCTCGAAGA 633 57 1472 Antisense
Sequence Source Affymetrix Proprietary Database