[Home] | [Total List]

[192237_s_at] acetylcholinesterase

Description Y48B6A.7 /REP_DB=WormBase Gene ID /WP=CE26734 /GEN=ace-4 /TR=Q9U2A4 /GB=CAB54444.2 /SUBMIT=HINXTON /CHR=2 /FEA=Sanger Annotation /DEF=acetylcholinesterase
Cluster 6grp_total > 16      4grp_total > 54      6grp_cgc > 13      6grp_cgc_sub > De      6grp_total_sub > Decrease      6grp_rule_based > S1      

Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 69
1 2 3 4 range
A 113.5
(3)
P 		90.2
(0.8)
P 		93
(1.1)
M 		49.1
(-3)
A 		64
B 82.2
(0.9)
P 		54.4
(-3)
A 		73.6
(-0.3)
P 		96.8
(3)
A 		42
C 79.4
(3)
P 		69.3
(1.2)
P 		44.8
(-3)
P 		46.2
(-2.8)
A 		35
avr 91.7
(3) 		71.3
(-1.4) 		70.5
(-1.6) 		64
(-3) 		28

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 115
1 2 3 4 5 6 range
A 148
(3)
P 		75.4
(-1.1)
P 		41.9
(-3)
A 		48.5
(-2.6)
A 		98.6
(0.2)
A 		73.7
(-1.2)
A 		106
B 104.6
(3)
P 		92.4
(2)
P 		64.6
(-0.4)
P 		67.7
(-0.1)
A 		33.9
(-3)
A 		49.5
(-1.7)
A 		71
C 96.8
(3)
P 		94.6
(2.8)
P 		51
(-1.3)
A 		32.8
(-3)
A 		41.9
(-2.1)
A 		46.3
(-1.7)
P 		64
avr 116.5
(3) 		87.5
(0.4) 		52.5
(-2.7) 		49.7
(-3) 		58.1
(-2.2) 		56.5
(-2.4) 		67
No Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 34
1 2 3 4 range
A 41.3
(3)
P 		19.6
(-0.8)
P 		24.3
(0)
M 		7.2
(-3)
A 		34
B 26.2
(3)
P 		13.4
(-3)
A 		17.1
(-1.3)
P 		20.6
(0.4)
A 		13
C 26.3
(3)
P 		19.9
(0.9)
P 		15.6
(-0.5)
P 		7.8
(-3)
A 		19
avr 31.3
(3) 		17.6
(-1.2) 		19
(-0.8) 		11.9
(-3) 		19

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 30
1 2 3 4 5 6 range
A 27.3
(2.3)
P 		26.8
(2.1)
P 		9.1
(-3)
A 		12.3
(-2.1)
A 		29.8
(3)
A 		17.9
(-0.4)
A 		21
B 36.4
(3)
P 		30.8
(1.5)
P 		15.7
(-2.5)
P 		17.9
(-1.9)
A 		13.8
(-3)
A 		18.5
(-1.8)
A 		23
C 35.9
(3)
P 		28.9
(1.6)
P 		13
(-1.7)
A 		6.6
(-3)
A 		13.6
(-1.6)
A 		15.5
(-1.2)
P 		29
avr 33.2
(3) 		28.8
(1.7) 		12.6
(-2.9) 		12.3
(-3) 		19.1
(-1) 		17.3
(-1.6) 		21
NetAffx Links Cluster Members
Consensus/Exemplar
Group Members
GeneChip Array Information
Probe Set ID 192237_s_at
GeneChip Array C. elegans Genome Array
Organism Common Name Nematode
Probe Design Information
Transcript ID(Array Design) affy.Ce.3652
Sequence Type Exemplar sequence
Representative Public ID Y48B6A.7 NCBI
Target Description Y48B6A.7 /REP_DB=WormBase Gene ID /WP=CE26734 /GEN=ace-4 /TR=Q9U2A4 /GB=CAB54444.2 /SUBMIT=HINXTON /CHR=2 /FEA=Sanger Annotation /DEF=acetylcholinesterase
Cluster Evidence This cluster is supported by a Sanger Annotation.
Annotation Method Description
Annotation Description This probe set was annotated using the Matching Probes based pipeline to a RefSeq identifier using 1 transcript(s).
Annotation Grade This is a grade A annotation.
Annotation Transcript Cluster (# of Matching Probes) NM_064561(11)
Transcript Assignments
Representative
Transcript		 Description Matching Probes Related Probesets by Grade
NM_064561 NCBI Caenorhabditis elegans Y48B6A.7 (acetylcholinesterase) mRNA, complete cds. 11/11 A 
GENEFINDER00000022987 ENSEMBL cdna:GeneFinder chromosome:CEL140:II:14200641:14205356:1 11/11 None
Y48B6A.7 ENSEMBL cdna:known chromosome:CEL140:II:14197937:14205344:1 gene:Y48B6A.7 11/11 A 
Annotation Notes
Cross Hybridizing mRNA Matched Probes Nature of Assignment Related Probesets by Grade
SNAP00000022963 5/11 Cross Hyb Matching Probes None
Genomic Alignment of Consensus/Exemplar Sequence
Assembly Wormbase March 2004
Alignment(s)
Position Identity Coverage Cytoband
chrII:14200637-14205353(+) 99.88 100.0
Public Domain and Genome References
Gene Title acetylcholinesterase
Gene Symbol ace-4
Ensembl Y48B6A.7
Entrez Gene 175074 Entrez gene
SwissProt O61372 EMBL-EBI
WormBase CE26734 Wormbase
Functional Annotations
Gene Ontology
GO Molecular Function (view graph)
ID Description Evidence Links
4104 cholinesterase activity inferred from electronic annotation QuickGO AmiGO
Protein Similarities
Method ID Description E-Value
blast CAB54444 Hypothetical protein Y48B6A.7 [Caenorhabditis elegans] ref|NP_496962.1| Y48B6A.7 [Caenorhabditis elegans] gb|AAC14017.1| acetylcholinesterase [Caenorhabditis elegans] 0.0
blast AAF80378 acetylcholinesterase [Caenorhabditis briggsae] sp|Q9NDG8|ACE4_CAEBR Acetylcholinesterase 4 precursor (AChE 4) 0.0
blast CAE59451 Hypothetical protein CBG02827 [Caenorhabditis briggsae] 0.0
blast CAB54444 Hypothetical protein Y48B6A.7 [Caenorhabditis elegans] ref|NP_496962.1| Y48B6A.7 [Caenorhabditis elegans] gb|AAC14017.1| acetylcholinesterase [Caenorhabditis elegans] 1.0E-98
blast AAF80378 acetylcholinesterase [Caenorhabditis briggsae] sp|Q9NDG8|ACE4_CAEBR Acetylcholinesterase 4 precursor (AChE 4) 4.0E-82
blast CAE59451 Hypothetical protein CBG02827 [Caenorhabditis briggsae] 2.0E-81
Protein Domains
Database ID Description E-Value
Pfam IPR002018 EMBL-EBI Carboxylesterase, type B 1.0E-126
Pfam IPR002018 EMBL-EBI Carboxylesterase, type B 2.7E-58
Pfam IPR002018 EMBL-EBI Carboxylesterase, type B 9.1E-26
Trans Membrane
ID Number Of Domains Domain Boundaries
NP_496962.1 1 7-29
Y48B6A.7 1 7-29
Sequence
Target Sequence 
>C. ELEGANS:192237_S_AT
tcgagttcgccacagaggaaacccgggaaagtttttgtgtatcattttacacagtcttcg
agcgcaaacccttggccaaaatggactggcgcaatgcatggatacgaaatcgaatatgtt
ttcggaattccgttaagttattcaaagaattataagcgaagagaacagatattctctcga
aaaattatgcagttttgggcgagttttgccaaaaatggaactccaaagctgcgtgttcta
aaaaatagcgaacattggccagagttcaacgagcagaatcattatcggttcttggatgca
gctccgcagtggctcaaatattcgaccgataaaaccgaaaaagcaagtggaatgccagtt
ttggagaagagtcaaggatacagagtacacggcatacttgacacaagaatactcatcaag
ctccttgacaacatattcctattggctactactctatattccattattcattttccaaat
tttctgaaatcatttctttccacccctgatctactagtccgaaaactccccccccccccc
cagtttcagttcaatttgcgggcttgtttcttttttgatctcttt

BLASTn GenBank NR
Probe Info
Probe Sequence(5'-3') Probe X Probe Y Probe Interrogation
Position 		Strandedness
TCGAGTTCGCCACAGAGGAAACCCG 166 597 1018 Antisense
TTACACAGTCTTCGAGCGCAAACCC 562 681 1064 Antisense
CGCAAACCCTTGGCCAAAATGGACT 79 253 1080 Antisense
GGAACTCCAAAGCTGCGTGTTCTAA 555 527 1234 Antisense
GCTCCGCAGTGGCTCAAATATTCGA 205 299 1318 Antisense
CAAGCTCCTTGACAACATATTCCTA 518 185 1434 Antisense
ATATTCCTATTGGCTACTACTCTAT 613 17 1450 Antisense
TTCTGAAATCATTTCTTTCCACCCC 669 693 1499 Antisense
TGATCTACTAGTCCGAAAACTCCCC 323 417 1524 Antisense
CCCCCAGTTTCAGTTCAATTTGCGG 156 259 1554 Antisense
GGCTTGTTTCTTTTTTGATCTCTTT 590 537 1578 Antisense
Sequence Source Affymetrix Proprietary Database