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[192232_at] serine/threonine-protein kinase

Description C49C8.1 /REP_DB=WormBase Gene ID /WP=CE08836 /TR=Q18707 /GB=AAB03128.1 /SUBMIT=ST.LOUIS /CHR=4 /FEA=Sanger Annotation /DEF=serine-threonine-protein kinase
Cluster 6grp_total > 66      4grp_total > 01      

Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 14
1 2 3 4 range
A 2.4
(-3)
A 		2.9
(-2.8)
A 		6.5
(-1.2)
A 		16.2
(3)
A 		14
B 6.1
(-1.3)
A 		4.1
(-2.5)
A 		3.2
(-3)
A 		13.4
(3)
A 		10
C 2.2
(-1.3)
A 		1.8
(-3)
A 		2.7
(0.9)
A 		3.2
(3)
A 		1
avr 3.6
(-2.5) 		2.9
(-3) 		4.1
(-2.1) 		10.9
(3) 		8

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 34
1 2 3 4 5 6 range
A 3.3
(-3)
A 		27.9
(1.4)
A 		4.6
(-2.8)
A 		3.9
(-2.9)
A 		5.9
(-2.5)
A 		36.7
(3)
A 		33
B 7
(-2.2)
A 		2.7
(-3)
A 		19
(-0)
A 		10.9
(-1.5)
A 		2.5
(-3)
A 		35.6
(3)
A 		33
C 2.3
(-3)
A 		6.4
(-1)
A 		7.1
(-0.7)
A 		2.9
(-2.7)
A 		4.5
(-2)
A 		14.9
(3)
A 		13
avr 4.2
(-3) 		12.3
(-1) 		10.2
(-1.6) 		5.9
(-2.6) 		4.3
(-3) 		29.1
(3) 		25
No Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 2
1 2 3 4 range
A 0.9
(-2)
A 		0.6
(-3)
A 		1.7
(0.7)
A 		2.4
(3)
A 		2
B 2
(0.7)
A 		1
(-2.1)
A 		0.7
(-3)
A 		2.8
(3)
A 		2
C 0.7
(-0)
A 		0.5
(-3)
A 		0.9
(3)
A 		0.5
(-3)
A 		0
avr 1.2
(-0.5) 		0.7
(-3) 		1.1
(-1) 		1.9
(3) 		1

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 13
1 2 3 4 5 6 range
A 0.6
(-3)
A 		9.9
(3)
A 		1
(-2.7)
A 		1
(-2.7)
A 		1.8
(-2.2)
A 		8.9
(2.4)
A 		9
B 2.4
(-2.3)
A 		0.9
(-3)
A 		4.6
(-1.2)
A 		2.9
(-2)
A 		1
(-3)
A 		13.3
(3)
A 		12
C 0.9
(-2.6)
A 		2
(-1.1)
A 		1.8
(-1.4)
A 		0.6
(-3)
A 		1.5
(-1.8)
A 		5
(3)
A 		4
avr 1.3
(-3) 		4.3
(-0.7) 		2.5
(-2.1) 		1.5
(-2.8) 		1.4
(-2.9) 		9.1
(3) 		8
NetAffx Links Cluster Members
Consensus/Exemplar
GeneChip Array Information
Probe Set ID 192232_at
GeneChip Array C. elegans Genome Array
Organism Common Name Nematode
Probe Design Information
Transcript ID(Array Design) affy.Ce.10258
Sequence Type Exemplar sequence
Representative Public ID C49C8.1 NCBI
Target Description C49C8.1 /REP_DB=WormBase Gene ID /WP=CE08836 /TR=Q18707 /GB=AAB03128.1 /SUBMIT=ST.LOUIS /CHR=4 /FEA=Sanger Annotation /DEF=serine-threonine-protein kinase
Cluster Evidence This cluster is supported by a Sanger Annotation.
Annotation Method Description
Annotation Description This probe set was annotated using the Matching Probes based pipeline to a RefSeq identifier using 1 transcript(s).
Annotation Grade This is a grade A annotation.
Annotation Transcript Cluster (# of Matching Probes) NM_069082(11)
Transcript Assignments
Representative
Transcript		 Description Matching Probes Related Probesets by Grade
NM_069082 NCBI Caenorhabditis elegans C49C8.1 (C49C8.1) mRNA, complete cds. 11/11 None
SNAP00000039875 ENSEMBL cdna:SNAP chromosome:CEL140:IV:8654586:8656788:1 10/11 None
GENEFINDER00000039879 ENSEMBL cdna:GeneFinder chromosome:CEL140:IV:8654586:8656762:1 10/11 None
C49C8.1 ENSEMBL cdna:known chromosome:CEL140:IV:8654586:8656788:1 gene:C49C8.1 11/11 None
Annotation Notes
There are no noteworthy cross hybridizing mRNAs found for this probe set.
Genomic Alignment of Consensus/Exemplar Sequence
Assembly Wormbase March 2004
Alignment(s)
Position Identity Coverage Cytoband
chrIV:8654591-8656794(+) 100.0 100.0
Public Domain and Genome References
Gene Title serine/threonine-protein kinase
Ensembl C49C8.1
Entrez Gene 177670 Entrez gene
SwissProt Q18707 EMBL-EBI
WormBase CE08836 Wormbase
Functional Annotations
Gene Ontology
GO Biological Process (view graph)
ID Description Evidence Links
6468 protein amino acid phosphorylation inferred from electronic annotation QuickGO AmiGO
GO Cellular Component (view graph)
ID Description Evidence Links
5634 nucleus inferred from electronic annotation QuickGO AmiGO
GO Molecular Function (view graph)
ID Description Evidence Links
3677 DNA binding inferred from electronic annotation QuickGO AmiGO
4672 protein kinase activity inferred from electronic annotation QuickGO AmiGO
4674 protein serine/threonine kinase activity inferred from electronic annotation QuickGO AmiGO
5524 ATP binding inferred from electronic annotation QuickGO AmiGO
Protein Similarities
Method ID Description E-Value
blast AAB03128 Hypothetical protein C49C8.1 [Caenorhabditis elegans] ref|NP_501483.1| C49C8.1 [Caenorhabditis elegans] 0.0
blast CAE59468 Hypothetical protein CBG02852 [Caenorhabditis briggsae] 1.0E-159
blast CAE59468 Hypothetical protein CBG02852 [Caenorhabditis briggsae] 1.0E-158
blast CAE59468 Hypothetical protein CBG02852 [Caenorhabditis briggsae] 1.0E-155
blast AAF36003 Hypothetical protein Y71F9AL.2 [Caenorhabditis elegans] ref|NP_491074.1| Y71F9AL.2 [Caenorhabditis elegans] 1.0E-149
blast AAF36003 Hypothetical protein Y71F9AL.2 [Caenorhabditis elegans] ref|NP_491074.1| Y71F9AL.2 [Caenorhabditis elegans] 1.0E-148
Protein Domains
Database ID Description E-Value
Pfam IPR000719 EMBL-EBI Protein kinase 2.7E-8
Sequence
Target Sequence 
>C. ELEGANS:192232_AT
tggagctaccctggacgagcaatgaggaaattgcactggaagaactaaaaaatcagtcga
gcattctgcgcttgttttctgacggtaagaatattgtatcaagctggattcatgatagaa
tattttcagacaaaaacccgtcccgattgacacccgaaatgcgtggtcaactggatgaaa
ttgataagaacctcaaatcatgcaactattatagtagtccaaagtatgatatcgtctatc
aatttttcaaagattcgatgacaaaggcaaaggttacctggacgacaccatatgattggg
agacaattggaaaatcgtcggaagatttttcgaagaaatccaacggaaaacgagcggttt
gggagaatcctggcgcctttttcaagaaagggcgctgggatgcacttcctctgccacttc
aatctccacatatttcgatcaggaaatcgtcgtcgaaacatccgaaaccatcagccaaag
gatccaagaaagccgttcaagcgagaattcagaatttcagtaaagaagattcggtggaag
ctgacgaggctccaacacc

BLASTn GenBank NR
Probe Info
Probe Sequence(5'-3') Probe X Probe Y Probe Interrogation
Position 		Strandedness
TGGAGCTACCCTGGACGAGCAATGA 698 545 938 Antisense
AATCAGTCGAGCATTCTGCGCTTGT 147 171 988 Antisense
TTCTGCGCTTGTTTTCTGACGGTAA 455 691 1001 Antisense
GACACCCGAAATGCGTGGTCAACTG 87 367 1086 Antisense
AAGAACCTCAAATCATGCAACTATT 510 151 1123 Antisense
AAGGTTACCTGGACGACACCATATG 160 159 1207 Antisense
GCGGTTTGGGAGAATCCTGGCGCCT 316 285 1291 Antisense
AAGAAAGGGCGCTGGGATGCACTTC 655 151 1321 Antisense
CCACTTCAATCTCCACATATTTCGA 489 275 1351 Antisense
AAACATCCGAAACCATCAGCCAAAG 207 129 1393 Antisense
TGGAAGCTGACGAGGCTCCAACACC 426 547 1472 Antisense
Sequence Source Affymetrix Proprietary Database