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[192225_at] serine-pyruvate aminotransferase

Description T14D7.1 /REP_DB=WormBase Gene ID /WP=CE23985 /TR=Q94055 /GB=CAB03364.2 /SUBMIT=HINXTON /CHR=2 /FEA=Sanger Annotation /DEF=serine-pyruvate aminotransferase
Cluster 6grp_highest_10_10 > 03      6grp_high1_10_10 > 10      4grp_highest_8_8 > 10      4grp_high_8_8 > 54      6grp_highest_nonorm > 32      6grp_total > 32      4grp_total > 57      6grp_highest_sub > De      6grp_total_sub > Hat      4grp_rule_based > L3      

Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 767
1 2 3 4 range
A 748.1
(-2.2)
P 		1148.2
(2.2)
P 		1223.8
(3)
P 		671.4
(-3)
P 		552
B 862.2
(-1.8)
P 		1185.1
(1.7)
P 		1306.6
(3)
P 		750.8
(-3)
P 		556
C 670.2
(-2)
P 		1072
(1.1)
P 		1311.3
(3)
P 		543.9
(-3)
P 		767
avr 760.2
(-2) 		1135.1
(1.6) 		1280.6
(3) 		655.4
(-3) 		625

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 787
1 2 3 4 5 6 range
A 1566.4
(3)
P 		1203.5
(0.2)
P 		1233
(0.5)
P 		1192.6
(0.1)
P 		1143.7
(-0.2)
P 		779.5
(-3)
P 		787
B 1331.8
(2.6)
P 		1196.8
(1.2)
P 		1364.8
(3)
P 		1267.8
(2)
P 		1155.4
(0.8)
P 		800.8
(-3)
P 		564
C 1162.1
(2.1)
P 		1133.1
(1.6)
P 		1222
(3)
P 		1210.7
(2.8)
P 		949.9
(-1.2)
P 		829.1
(-3)
P 		393
avr 1353.4
(3) 		1177.8
(1.1) 		1273.3
(2.1) 		1223.7
(1.6) 		1083
(0.1) 		803.1
(-3) 		550
No Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 365
1 2 3 4 range
A 272.4
(1.7)
P 		249.2
(1.1)
P 		319.9
(3)
P 		98.3
(-3)
P 		222
B 275
(1.8)
P 		292.7
(2.6)
P 		302.8
(3)
P 		160
(-3)
P 		143
C 221.9
(-0.9)
P 		308.2
(0.6)
P 		457
(3)
P 		91.7
(-3)
P 		365
avr 256.4
(0.4) 		283.4
(1.1) 		359.9
(3) 		116.7
(-3) 		243

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 280
1 2 3 4 5 6 range
A 288.8
(-0.5)
P 		428
(3)
P 		268.5
(-1)
P 		302.5
(-0.2)
P 		345.1
(0.9)
P 		189.8
(-3)
P 		238
B 463.4
(2.8)
P 		398.4
(0.5)
P 		331.4
(-1.8)
P 		335.8
(-1.7)
P 		469.4
(3)
P 		298.6
(-3)
P 		171
C 430.7
(3)
P 		345.7
(0.3)
P 		311
(-0.8)
P 		243.5
(-3)
P 		307.4
(-1)
P 		277.6
(-1.9)
P 		187
avr 394.3
(3) 		390.7
(2.8) 		303.6
(-0.9) 		293.9
(-1.3) 		374
(2.1) 		255.3
(-3) 		139
NetAffx Links Cluster Members
Consensus/Exemplar
GeneChip Array Information
Probe Set ID 192225_at
GeneChip Array C. elegans Genome Array
Organism Common Name Nematode
Probe Design Information
Transcript ID(Array Design) affy.Ce.3532
Sequence Type Exemplar sequence
Representative Public ID T14D7.1 NCBI
Target Description T14D7.1 /REP_DB=WormBase Gene ID /WP=CE23985 /TR=Q94055 /GB=CAB03364.2 /SUBMIT=HINXTON /CHR=2 /FEA=Sanger Annotation /DEF=serine-pyruvate aminotransferase
Cluster Evidence This cluster is supported by a Sanger Annotation.
Annotation Method Description
Annotation Description This probe set was annotated using the Matching Probes based pipeline to a RefSeq identifier using 1 transcript(s).
Annotation Grade This is a grade A annotation.
Annotation Transcript Cluster (# of Matching Probes) NM_063484(11)
Transcript Assignments
Representative
Transcript		 Description Matching Probes Related Probesets by Grade
NM_063484 NCBI Caenorhabditis elegans T14D7.1 (T14D7.1) mRNA, complete cds. 11/11 None
SNAP00000027261 ENSEMBL cdna:SNAP chromosome:CEL140:II:8846980:8848633:1 11/11 None
GENEFINDER00000027264 ENSEMBL cdna:GeneFinder chromosome:CEL140:II:8846980:8848736:1 11/11 None
T14D7.1 ENSEMBL cdna:known chromosome:CEL140:II:8846236:8848814:1 gene:T14D7.1 11/11 None
Annotation Notes
There are no noteworthy cross hybridizing mRNAs found for this probe set.
Genomic Alignment of Consensus/Exemplar Sequence
Assembly Wormbase March 2004
Alignment(s)
Position Identity Coverage Cytoband
chrII:8846232-8848674(+) 100.0 100.0
Public Domain and Genome References
Gene Title serine-pyruvate aminotransferase
Ensembl T14D7.1
Entrez Gene 174414 Entrez gene
SwissProt Q94055 EMBL-EBI
WormBase CE23985 Wormbase
Functional Annotations
Ortholog
ID Title Organism
ATGENOME1:14737_S_AT serine-glyoxylate aminotransferase-related at
ATH1-121501:263350_AT serine-glyoxylate aminotransferase-related at
CANINE_2:CFA.20905.1.S1_AT similar to Serine--pyruvate aminotransferase (SPT) (Alanine--glyoxylate aminotransferase) (AGT) cfa
CANINE_2:CFA.20905.1.S1_X_AT similar to Serine--pyruvate aminotransferase (SPT) (Alanine--glyoxylate aminotransferase) (AGT) cfa
CANINE_2:CFAAFFX.19771.1.S1_S_AT similar to Serine--pyruvate aminotransferase (SPT) (Alanine--glyoxylate aminotransferase) (AGT) cfa
DROSOPHILA_2:1637872_AT Serine pyruvate aminotransferase dm
DROSGENOME1:153046_AT Serine pyruvate aminotransferase dm
HG-U133_PLUS_2:206957_AT alanine-glyoxylate aminotransferase (oxalosis I; hyperoxaluria I; glycolicaciduria; serine-pyruvate aminotransferase) hs
HG-U133A:206957_AT alanine-glyoxylate aminotransferase (oxalosis I; hyperoxaluria I; glycolicaciduria; serine-pyruvate aminotransferase) hs
HG-FOCUS:206957_AT alanine-glyoxylate aminotransferase (oxalosis I; hyperoxaluria I; glycolicaciduria; serine-pyruvate aminotransferase) hs
HG-U133A_2:206957_AT alanine-glyoxylate aminotransferase (oxalosis I; hyperoxaluria I; glycolicaciduria; serine-pyruvate aminotransferase) hs
HG-U133_PLUS_2:210327_S_AT alanine-glyoxylate aminotransferase (oxalosis I; hyperoxaluria I; glycolicaciduria; serine-pyruvate aminotransferase) hs
HG-U133A:210327_S_AT alanine-glyoxylate aminotransferase (oxalosis I; hyperoxaluria I; glycolicaciduria; serine-pyruvate aminotransferase) hs
HG-FOCUS:210327_S_AT alanine-glyoxylate aminotransferase (oxalosis I; hyperoxaluria I; glycolicaciduria; serine-pyruvate aminotransferase) hs
HG-U133A_2:210327_S_AT alanine-glyoxylate aminotransferase (oxalosis I; hyperoxaluria I; glycolicaciduria; serine-pyruvate aminotransferase) hs
HG-U133_PLUS_2:210326_AT alanine-glyoxylate aminotransferase (oxalosis I; hyperoxaluria I; glycolicaciduria; serine-pyruvate aminotransferase) hs
HG-U133A:210326_AT alanine-glyoxylate aminotransferase (oxalosis I; hyperoxaluria I; glycolicaciduria; serine-pyruvate aminotransferase) hs
HG-U133A_2:210326_AT alanine-glyoxylate aminotransferase (oxalosis I; hyperoxaluria I; glycolicaciduria; serine-pyruvate aminotransferase) hs
HU35KSUBC:RC_T73739_S_AT alanine-glyoxylate aminotransferase (oxalosis I; hyperoxaluria I; glycolicaciduria; serine-pyruvate aminotransferase) hs
HUGENEFL:X53414_AT alanine-glyoxylate aminotransferase (oxalosis I; hyperoxaluria I; glycolicaciduria; serine-pyruvate aminotransferase) hs
U133_X3P:G7706736_3P_AT alanine-glyoxylate aminotransferase (oxalosis I; hyperoxaluria I; glycolicaciduria; serine-pyruvate aminotransferase) hs
U133_X3P:G219432_3P_S_AT alanine-glyoxylate aminotransferase (oxalosis I; hyperoxaluria I; glycolicaciduria; serine-pyruvate aminotransferase) hs
HG-U95AV2:37880_AT alanine-glyoxylate aminotransferase (oxalosis I; hyperoxaluria I; glycolicaciduria; serine-pyruvate aminotransferase) hs
MU11KSUBA:AF027730_G_AT alanine-glyoxylate aminotransferase mm
MU11KSUBA:AF027730_AT alanine-glyoxylate aminotransferase mm
MG-U74AV2:93625_AT alanine-glyoxylate aminotransferase mm
MOE430A:1418833_AT alanine-glyoxylate aminotransferase mm
MOUSE430A_2:1418833_AT alanine-glyoxylate aminotransferase mm
MOUSE430_2:1418833_AT alanine-glyoxylate aminotransferase mm
MU19KSUBA:TC20536_S_AT Alanine-glyoxylate aminotransferase, mRNA (cDNA clone MGC:35967 IMAGE:5099627) mm
RG-U34A:M35270COMPLETE_SEQ_R_AT alanine-glyoxylate aminotransferase rn
RG-U34A:M35270COMPLETE_SEQ_I_AT alanine-glyoxylate aminotransferase rn
RG-U34A:E01050CDS_G_AT alanine-glyoxylate aminotransferase rn
RG-U34A:E01050CDS_AT alanine-glyoxylate aminotransferase rn
RG-U34A:D13667CDS_S_AT alanine-glyoxylate aminotransferase rn
RG-U34A:X06357CDS_S_AT alanine-glyoxylate aminotransferase rn
RG-U34C:RC_AI137065_G_AT alanine-glyoxylate aminotransferase rn
RAE230A:1387215_AT alanine-glyoxylate aminotransferase rn
RAT230_2:1387215_AT alanine-glyoxylate aminotransferase rn
YEAST_2:1770767_AT Alanine : glyoxylate aminotransferase, catalyzes the synthesis of glycine from glyoxylate, which is one of three pathways for glycine biosynthesis in yeast; has similarity to mammalian and plant alanine : glyoxylate aminotransferases Sc
Gene Ontology
GO Biological Process (view graph)
ID Description Evidence Links
8152 metabolism inferred from electronic annotation QuickGO AmiGO
GO Molecular Function (view graph)
ID Description Evidence Links
8483 transaminase activity inferred from electronic annotation QuickGO AmiGO
Protein Similarities
Method ID Description E-Value
blast CAB03364 Hypothetical protein T14D7.1 [Caenorhabditis elegans] ref|NP_495885.1| T14D7.1 [Caenorhabditis elegans] 0.0
blast CAE59750 Hypothetical protein CBG03195 [Caenorhabditis briggsae] 0.0
blast AAK26375 class V aminotransferase [Heterodera glycines] 1.0E-133
Protein Domains
Database ID Description E-Value
Pfam IPR000192 EMBL-EBI Aminotransferase, class V 8.2E-36
Pfam IPR000192 EMBL-EBI Aminotransferase, class V 8.2E-36
Pfam IPR000192 EMBL-EBI Aminotransferase, class V 2.0E-33
Sequence
Target Sequence 
>C. ELEGANS:192225_AT
ttccttgttgatacggtggcgtccctcggtggaactccatttgcagcagatgatctgaaa
gttgattgtgtctattcggcaacccagaaagttctcaacgctccaccaggacttgcgcct
atctcattctccgatcgagccatggaaaaaatccggaaccgaaaacaacgcgtcgcctcg
ttctactttgatgccatcgaattgggcaactattggggttgtgatggagaattgaaaaga
tatcaccacactgctccaatctccactgtatatgctcttcgtgcagcactttctgcaatt
gcaaaagaaggaattgatgaatcaatccaaagacataaagataatgctcaagtgttgtat
gctactctga

BLASTn GenBank NR
Probe Info
Probe Sequence(5'-3') Probe X Probe Y Probe Interrogation
Position 		Strandedness
TTCCTTGTTGATACGGTGGCGTCCC 177 687 601 Antisense
TCCCTCGGTGGAACTCCATTTGCAG 71 597 622 Antisense
GGAACTCCATTTGCAGCAGATGATC 589 529 631 Antisense
TTGATTGTGTCTATTCGGCAACCCA 22 705 662 Antisense
AACCCAGAAAGTTCTCAACGCTCCA 236 147 681 Antisense
TCTCATTCTCCGATCGAGCCATGGA 448 613 722 Antisense
CCTCGTTCTACTTTGATGCCATCGA 451 267 776 Antisense
TGAAAAGATATCACCACACTGCTCC 417 573 833 Antisense
CAATCTCCACTGTATATGCTCTTCG 488 181 857 Antisense
ATATGCTCTTCGTGCAGCACTTTCT 96 15 870 Antisense
GCTCAAGTGTTGTATGCTACTCTGA 588 301 946 Antisense
Sequence Source Affymetrix Proprietary Database