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[192206_at] zinc-finger DNA-binding protein

Description F53B1.8 /REP_DB=WormBase Gene ID /WP=CE04648 /TR=Q20702 /GB=AAB52651.1 /SUBMIT=ST.LOUIS /CHR=X /FEA=Sanger Annotation /DEF=zinc-finger DNA-binding protein
Cluster 6grp_highest_10_10 > 71      6grp_high1_10_10 > 18      4grp_highest_8_8 > 59      4grp_high_8_8 > 25      6grp_highest_nonorm > 90      6grp_total > 17      4grp_total > 38      6grp_highest_sub > De      6grp_total_sub > Decrease      6grp_rule_based > S1      4grp_rule_based > L1      

Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 177
1 2 3 4 range
A 292.3
(3)
P 		115.4
(-3)
P 		121.2
(-2.8)
P 		175.3
(-1)
P 		177
B 205.1
(3)
P 		175.7
(0.5)
P 		133.9
(-3)
P 		138.2
(-2.6)
P 		71
C 246.2
(3)
P 		183.5
(-1.4)
P 		160
(-3)
P 		165.9
(-2.6)
P 		86
avr 247.9
(3) 		158.2
(-1.9) 		138.4
(-3) 		159.8
(-1.8) 		110

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 234
1 2 3 4 5 6 range
A 201.7
(3)
P 		186.5
(2.2)
P 		92.6
(-3)
P 		142.4
(-0.3)
P 		142.9
(-0.2)
P 		192.1
(2.5)
P 		109
B 227.1
(3)
P 		165.7
(-0.1)
P 		107.6
(-3)
P 		158.3
(-0.5)
P 		129.7
(-1.9)
P 		140.9
(-1.3)
P 		120
C 326.3
(3)
P 		190.6
(-0.6)
P 		165.9
(-1.3)
P 		112.1
(-2.7)
P 		139.4
(-2)
P 		100.7
(-3)
P 		226
avr 251.7
(3) 		180.9
(-0.3) 		122
(-3) 		137.6
(-2.3) 		137.3
(-2.3) 		144.6
(-2) 		130
No Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 81
1 2 3 4 range
A 106.4
(3)
P 		25.1
(-3)
P 		31.7
(-2.5)
P 		25.7
(-3)
P 		81
B 65.4
(3)
P 		43.4
(-0.7)
P 		31
(-2.7)
P 		29.5
(-3)
P 		36
C 81.5
(3)
P 		52.7
(-0.2)
P 		55.8
(0.1)
P 		28
(-3)
P 		54
avr 84.4
(3) 		40.4
(-1.7) 		39.5
(-1.8) 		27.7
(-3) 		57

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 101
1 2 3 4 5 6 range
A 37.2
(-0.8)
P 		66.3
(3)
P 		20.2
(-3)
P 		36.1
(-0.9)
P 		43.1
(-0)
P 		46.8
(0.5)
P 		46
B 79
(3)
P 		55.2
(0.3)
P 		26.1
(-3)
P 		41.9
(-1.2)
P 		52.7
(0)
P 		52.5
(-0)
P 		53
C 121
(3)
P 		58.2
(-0.8)
P 		42.2
(-1.8)
P 		22.5
(-3)
P 		45.1
(-1.6)
P 		33.7
(-2.3)
P 		99
avr 79.1
(3) 		59.9
(0.7) 		29.5
(-3) 		33.5
(-2.5) 		47
(-0.9) 		44.3
(-1.2) 		50
NetAffx Links Cluster Members
Consensus/Exemplar
GeneChip Array Information
Probe Set ID 192206_at
GeneChip Array C. elegans Genome Array
Organism Common Name Nematode
Probe Design Information
Transcript ID(Array Design) affy.Ce.18539
Sequence Type Exemplar sequence
Representative Public ID F53B1.8 NCBI
Target Description F53B1.8 /REP_DB=WormBase Gene ID /WP=CE04648 /TR=Q20702 /GB=AAB52651.1 /SUBMIT=ST.LOUIS /CHR=X /FEA=Sanger Annotation /DEF=zinc-finger DNA-binding protein
Cluster Evidence This cluster is supported by a Sanger Annotation.
Annotation Method Description
Annotation Description This probe set was annotated using the Matching Probes based pipeline to a RefSeq identifier using 1 transcript(s).
Annotation Grade This is a grade A annotation.
Annotation Transcript Cluster (# of Matching Probes) NM_075993(11)
Transcript Assignments
Representative
Transcript		 Description Matching Probes Related Probesets by Grade
NM_075993 NCBI Caenorhabditis elegans F53B1.8 (F53B1.8) mRNA, complete cds. 11/11 None
SNAP00000022995 ENSEMBL cdna:SNAP chromosome:CEL140:X:2124105:2130183:-1 11/11 None
GENEFINDER00000023002 ENSEMBL cdna:GeneFinder chromosome:CEL140:X:2124105:2130183:-1 11/11 None
F53B1.8 ENSEMBL cdna:known chromosome:CEL140:X:2123411:2130235:-1 gene:F53B1.8 11/11 None
Annotation Notes
There are no noteworthy cross hybridizing mRNAs found for this probe set.
Genomic Alignment of Consensus/Exemplar Sequence
Assembly Wormbase March 2004
Alignment(s)
Position Identity Coverage Cytoband
chrX:2124982-2130183(-) 97.86 100.0
Public Domain and Genome References
Gene Title zinc-finger DNA-binding protein
Ensembl F53B1.8
Entrez Gene 180528 Entrez gene
SwissProt Q20702 EMBL-EBI
WormBase CE04648 Wormbase
Functional Annotations
Ortholog
ID Title Organism
HG-U133_PLUS_2:222071_S_AT solute carrier organic anion transporter family, member 4C1 hs
HG-U133A_2:222071_S_AT solute carrier organic anion transporter family, member 4C1 hs
HG-U133A:222071_S_AT solute carrier organic anion transporter family, member 4C1 hs
U133_X3P:HS.127648.1.S1_3P_A_AT solute carrier organic anion transporter family, member 4C1 hs
HG-U95E:88921_AT solute carrier organic anion transporter family, member 4C1 hs
MG-U74BV2:115022_AT solute carrier organic anion transporter family, member 4C1 mm
MOE430B:1437870_AT solute carrier organic anion transporter family, member 4C1 mm
MOUSE430_2:1437870_AT solute carrier organic anion transporter family, member 4C1 mm
MOE430B:1460616_AT solute carrier organic anion transporter family, member 4C1 mm
MOUSE430_2:1460616_AT solute carrier organic anion transporter family, member 4C1 mm
MOE430B:1458804_AT Solute carrier organic anion transporter family, member 4C1 (Slco4c1), mRNA mm
MOUSE430_2:1458804_AT Solute carrier organic anion transporter family, member 4C1 (Slco4c1), mRNA mm
Gene Ontology
GO Biological Process (view graph)
ID Description Evidence Links
6810 transport inferred from electronic annotation QuickGO AmiGO
GO Cellular Component (view graph)
ID Description Evidence Links
16020 membrane inferred from electronic annotation QuickGO AmiGO
GO Molecular Function (view graph)
ID Description Evidence Links
5215 transporter activity inferred from electronic annotation QuickGO AmiGO
Protein Similarities
Method ID Description E-Value
blast AAB52651 Hypothetical protein F53B1.8 [Caenorhabditis elegans] ref|NP_508394.1| F53B1.8 [Caenorhabditis elegans] 0.0
blast CAE68348 Hypothetical protein CBG14081 [Caenorhabditis briggsae] 0.0
blast XP_611249 PREDICTED: similar to Solute carrier organic anion transporter family member 4A1 (Solute carrier family 21 member 12) (Sodium-independent organic anion transporter E) (Organic anion transporting polypeptide E) (OATP-E) (Colon organic anion transporter) (Organ... [Bos taurus] 8.0E-94
Protein Domains
Database ID Description E-Value
Pfam IPR004157 EMBL-EBI Organic anion transporter polypeptide (OATP), C-terminal 1.0E-126
Pfam IPR004157 EMBL-EBI Organic anion transporter polypeptide (OATP), C-terminal 1.0E-126
Trans Membrane
ID Number Of Domains Domain Boundaries
NP_508394.1 12 106-128,143-165,172-194,244-266,279-301,334-356,468-490,510-532,545-567,678-700,713-735,766-788
F53B1.8 12 106-128,143-165,172-194,244-266,279-301,334-356,468-490,510-532,545-567,678-700,713-735,766-788
SNAP00000022995 12 106-128,143-165,172-194,244-266,279-301,334-356,441-463,483-505,518-540,651-673,686-708,739-761
GENEFINDER00000023002 12 106-128,143-165,172-194,244-266,279-301,334-356,441-463,483-505,518-540,651-673,686-708,739-761
Sequence
Target Sequence 
>C. ELEGANS:192206_AT
gacggtcgacaattcacgtactactcaccttgttatgctggatgctccgaaacatattcg
gcatcattgaaggagtacaccgaatgcagttgcgtgccgacgaatactaaaaaccgacca
cgtattgtgaaaaaaggtgtttgcgagccacagtgcactgaattgctttggttccttctg
ctcttcgcaccactttccttctgtacgttcgcaattgctgttccgatcatctctgtcatc
ctgagaactgtcgattacaacgagcgatcatttgcattgggaattcagtggatcatgatc
agagtgattggtacgattcctgcgccagttctttttggatggatgttcgatgtctcgtgt
ataaagtatcaatcggactcttgtggaagctcgagtggcggatgcctgatgtattcgaat
caataccttgccaacttgtttttgacatttacaatcagcgggcaaatcatcacattggca
attcttattgtggttctgatgattttcggagcagccctcaatgatgatgcca

BLASTn GenBank NR
Probe Info
Probe Sequence(5'-3') Probe X Probe Y Probe Interrogation
Position 		Strandedness
GACGGTCGACAATTCACGTACTACT 585 375 1870 Antisense
GTACTACTCACCTTGTTATGCTGGA 481 459 1887 Antisense
GTACACCGAATGCAGTTGCGTGCCG 340 461 1944 Antisense
GTTTGCGAGCCACAGTGCACTGAAT 514 451 2008 Antisense
GCACTGAATTGCTTTGGTTCCTTCT 661 315 2024 Antisense
CTTTCCTTCTGTACGTTCGCAATTG 217 223 2062 Antisense
TCGCAATTGCTGTTCCGATCATCTC 350 601 2078 Antisense
TCCGATCATCTCTGTCATCCTGAGA 159 595 2091 Antisense
TTCCTGCGCCAGTTCTTTTTGGATG 470 699 2186 Antisense
GTGGCGGATGCCTGATGTATTCGAA 293 491 2264 Antisense
GGAGCAGCCCTCAATGATGATGCCA 645 519 2377 Antisense
Sequence Source Affymetrix Proprietary Database