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[192178_s_at] importin alpha, nuclear transport factor

Description T19B10.7 /REP_DB=WormBase Gene ID /WP=CE06461 /TR=Q22560 /GB=CAA98540.1 /SUBMIT=HINXTON /CHR=5 /FEA=Sanger Annotation /DEF=nucleoprotein interactor 1 like
Cluster 6grp_highest_10_10 > 77      6grp_high1_10_10 > 86      4grp_highest_8_8 > 53      4grp_high_8_8 > 17      6grp_highest_nonorm > 93      6grp_total > 77      4grp_total > 31      6grp_highest_sub > Da      6grp_cgc > 58      6grp_high1_sub > In      6grp_cgc_sub > In      6grp_total_sub > Increase      6grp_rule_based > S6      

Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 202
1 2 3 4 range
A 333.7
(3)
P 		188.9
(-3)
P 		232.8
(-1.2)
P 		287.3
(1.1)
P 		145
B 318.2
(3)
P 		264.9
(-0.7)
P 		232.5
(-3)
P 		285.9
(0.7)
P 		86
C 391.1
(3)
P 		255.6
(-2.1)
P 		232.3
(-3)
P 		319.7
(0.3)
P 		159
avr 347.7
(3) 		236.5
(-2.8) 		232.5
(-3) 		297.6
(0.4) 		115

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 634
1 2 3 4 5 6 range
A 325
(-2.8)
P 		312.5
(-3)
P 		420.1
(-1.3)
P 		314.3
(-3)
P 		522.2
(0.3)
P 		688.8
(3)
P 		376
B 294.3
(-3)
P 		310.4
(-2.8)
P 		453.8
(-1.4)
P 		352.3
(-2.4)
P 		534.2
(-0.6)
P 		889.8
(3)
P 		596
C 255.4
(-3)
P 		310.9
(-2.5)
P 		273.8
(-2.8)
P 		311.1
(-2.5)
P 		400.6
(-1.6)
P 		887.9
(3)
P 		633
avr 291.6
(-3) 		311.3
(-2.8) 		382.6
(-2) 		325.9
(-2.6) 		485.7
(-0.8) 		822.2
(3) 		531
No Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 89
1 2 3 4 range
A 121.5
(3)
P 		41
(-3)
P 		60.9
(-1.5)
P 		42.1
(-2.9)
P 		81
B 101.5
(3)
P 		65.4
(-1.6)
P 		53.9
(-3)
P 		60.9
(-2.1)
P 		48
C 129.5
(3)
P 		73.5
(-1.4)
P 		81
(-0.8)
P 		53.9
(-3)
P 		76
avr 117.5
(3) 		60
(-2.3) 		65.3
(-1.8) 		52.3
(-3) 		65

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 272
1 2 3 4 5 6 range
A 59.9
(-3)
P 		111.1
(-0.2)
P 		91.5
(-1.2)
P 		79.7
(-1.9)
P 		157.6
(2.4)
P 		167.7
(3)
P 		108
B 102.4
(-2.8)
P 		103.3
(-2.7)
P 		110.2
(-2.6)
P 		93.3
(-3)
P 		217
(0.1)
P 		331.8
(3)
P 		239
C 94.7
(-2.2)
P 		94.9
(-2.2)
P 		69.7
(-2.8)
P 		62.6
(-3)
P 		129.6
(-1.3)
P 		297.2
(3)
P 		235
avr 85.7
(-2.8) 		103.1
(-2.2) 		90.5
(-2.6) 		78.5
(-3) 		168.1
(-0.1) 		265.6
(3) 		187
NetAffx Links Cluster Members
Consensus/Exemplar
Group Members
GeneChip Array Information
Probe Set ID 192178_s_at
GeneChip Array C. elegans Genome Array
Organism Common Name Nematode
Probe Design Information
Transcript ID(Array Design) affy.Ce.13254
Sequence Type Exemplar sequence
Representative Public ID T19B10.7 NCBI
Target Description T19B10.7 /REP_DB=WormBase Gene ID /WP=CE06461 /TR=Q22560 /GB=CAA98540.1 /SUBMIT=HINXTON /CHR=5 /FEA=Sanger Annotation /DEF=nucleoprotein interactor 1 like
Cluster Evidence This cluster is supported by a Sanger Annotation.
Annotation Method Description
Annotation Description This probe set was annotated using the Matching Probes based pipeline to a RefSeq identifier using 1 transcript(s).
Annotation Grade This is a grade A annotation.
Annotation Transcript Cluster (# of Matching Probes) NM_073453(11)
Transcript Assignments
Representative
Transcript		 Description Matching Probes Related Probesets by Grade
NM_073453 NCBI Caenorhabditis elegans IMportin Alpha family member (ima-1) (ima-1) mRNA, complete cds. 11/11 A 
SNAP00000024748 ENSEMBL cdna:SNAP chromosome:CEL140:V:11242294:11244057:1 11/11 None
GENEFINDER00000024760 ENSEMBL cdna:GeneFinder chromosome:CEL140:V:11242294:11244057:1 11/11 None
T19B10.7.2 ENSEMBL cdna:known chromosome:CEL140:V:11242263:11244356:1 gene:T19B10.7 11/11 None
T19B10.7.1 ENSEMBL cdna:known chromosome:CEL140:V:11242293:11244368:1 gene:T19B10.7 11/11 None
Annotation Notes
There are no noteworthy cross hybridizing mRNAs found for this probe set.
Genomic Alignment of Consensus/Exemplar Sequence
Assembly Wormbase March 2004
Alignment(s)
Position Identity Coverage Cytoband
chrV:11242293-11244057(+) 100.0 100.0
Public Domain and Genome References
Gene Title importin alpha, nuclear transport factor
Gene Symbol ima-1
Ensembl T19B10.7
Entrez Gene 179555 Entrez gene
SwissProt Q22560 EMBL-EBI
WormBase CE06461 Wormbase
Functional Annotations
Gene Ontology
GO Biological Process (view graph)
ID Description Evidence Links
6606 protein import into nucleus inferred from electronic annotation QuickGO AmiGO
6886 intracellular protein transport inferred from electronic annotation QuickGO AmiGO
GO Molecular Function (view graph)
ID Description Evidence Links
8565 protein transporter activity inferred from electronic annotation QuickGO AmiGO
Protein Similarities
Method ID Description E-Value
blast CAA98540 Hypothetical protein T19B10.7 [Caenorhabditis elegans] ref|NP_505854.1| IMportin Alpha family member (ima-1) [Caenorhabditis elegans] sp|Q22560|IMA1_CAEEL Importin alpha-1 subunit (Karyopherin alpha-1 subunit) 0.0
blast AAB97173 importin alpha 1 [Caenorhabditis elegans] pir||T42404 importin alpha 3 - Caenorhabditis elegans 0.0
blast CAE75198 Hypothetical protein CBG23145 [Caenorhabditis briggsae] 0.0
Protein Domains
Database ID Description E-Value
Pfam IPR002652 EMBL-EBI Importin alpha-like protein, beta-binding region 1.7E-31
Sequence
Target Sequence 
>C. ELEGANS:192178_S_AT
gaagtatgctttatcatctccaatatttgcgtcgaaggcgagcaaacaatcgataaatta
atttcatctggagtgttacgagaagttgctcgagtcatggaagcttccgaatatcgttct
cggcgagaagctgcgtttgtcatttgccattgttgcgcttcagcaaaccagaaacatctc
gaatatgttgttgaattgggaatgctctctgcatttacagatttactgacgtgtatggat
gtctctctcgtttcctatattcttgatgcaatttacttacttcttcaatttggtgagatg
cgtttattacctgataattcgaatccggttgcaataaaattggaggaaataggatgtcgt
gaaaagctggaattcttatgtgaaagtcaaagtgtagatattcatgctcgagcatatacc
attattgataggttctatgtagacgacgatgctccactaaatgatgatccctttgctggt
tatc

BLASTn GenBank NR
Probe Info
Probe Sequence(5'-3') Probe X Probe Y Probe Interrogation
Position 		Strandedness
GAAGTATGCTTTATCATCTCCAATA 398 337 1030 Antisense
GTTGCTCGAGTCATGGAAGCTTCCG 148 439 1114 Antisense
GAAGCTTCCGAATATCGTTCTCGGC 473 341 1129 Antisense
TCTCGGCGAGAAGCTGCGTTTGTCA 208 611 1147 Antisense
TGTCATTTGCCATTGTTGCGCTTCA 367 559 1167 Antisense
GTTGAATTGGGAATGCTCTCTGCAT 128 439 1219 Antisense
GACGTGTATGGATGTCTCTCTCGTT 591 377 1257 Antisense
GATGCAATTTACTTACTTCTTCAAT 340 409 1294 Antisense
AGTGTAGATATTCATGCTCGAGCAT 482 59 1420 Antisense
GACGACGATGCTCCACTAAATGATG 205 379 1471 Antisense
AATGATGATCCCTTTGCTGGTTATC 626 163 1489 Antisense
Sequence Source Affymetrix Proprietary Database