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[192169_s_at] T-complex protein

Description K01C8.10 /REP_DB=WormBase Gene ID /WP=CE02262 /GEN=cct-4 /TR=SW:P47208 /GB=CAA88861.1 /SUBMIT=HINXTON /CHR=2 /FEA=Sanger Annotation /DEF=T-complex protein
Cluster 6grp_highest_10_10 > 55      6grp_high1_10_10 > 45      4grp_highest_8_8 > 22      4grp_high_8_8 > 14      6grp_highest_nonorm > 38      6grp_total > 46      4grp_total > 09      6grp_cgc > 35      6grp_cgc_sub > Cu      4grp_rule_based > L4      

Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 15693
1 2 3 4 range
A 6427
(-3)
P 		8089.9
(-2.3)
P 		8572.9
(-2.2)
P 		21666
(3)
P 		15239
B 6471.3
(-3)
P 		7236
(-2.7)
P 		8326.4
(-2.2)
P 		20183.1
(3)
P 		13712
C 5973
(-3)
P 		6641.3
(-2.7)
P 		7850.5
(-2.3)
P 		21237.9
(3)
P 		15265
avr 6290.4
(-3) 		7322.4
(-2.6) 		8249.9
(-2.2) 		21029
(3) 		14739

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 3184
1 2 3 4 5 6 range
A 6714
(0.9)
P 		7393.9
(3)
P 		5507.7
(-2.9)
P 		5974.7
(-1.4)
P 		5468.1
(-3)
P 		7010
(1.8)
P 		1926
B 5600.2
(-0)
P 		7019
(3)
P 		7037.1
(3)
P 		6556.4
(2)
P 		4210
(-3)
P 		6270
(1.4)
P 		2827
C 5767.1
(-1)
P 		6757.4
(1.9)
P 		7116.4
(3)
P 		6935.7
(2.5)
P 		5102.1
(-3)
P 		6290.5
(0.5)
P 		2014
avr 6027.1
(0.1) 		7056.8
(3) 		6553.7
(1.6) 		6488.9
(1.4) 		4926.7
(-3) 		6523.5
(1.5) 		2130
No Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 2545
1 2 3 4 range
A 2340.1
(-0.5)
P 		1756.1
(-3)
P 		2241.1
(-0.9)
P 		3171.5
(3)
P 		1415
B 2063.6
(-2.3)
P 		1787.1
(-3)
P 		1929.4
(-2.7)
P 		4301
(3)
P 		2514
C 1977.2
(-2.8)
P 		1909.4
(-3)
P 		2736.1
(-0)
P 		3581
(3)
P 		1672
avr 2127
(-2) 		1817.5
(-3) 		2302.2
(-1.4) 		3684.5
(3) 		1867

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 1430
1 2 3 4 5 6 range
A 1237.7
(-2.8)
P 		2629.6
(3)
P 		1199.5
(-3)
P 		1515.3
(-1.7)
P 		1650
(-1.1)
P 		1706.7
(-0.9)
P 		1430
B 1948.6
(-0.7)
P 		2336.3
(3)
P 		1708.8
(-3)
P 		1736.6
(-2.7)
P 		1710.5
(-3)
P 		2338
(3)
P 		629
C 2137.6
(3)
P 		2061.9
(2.4)
P 		1811.3
(0.4)
P 		1394.8
(-3)
P 		1651
(-0.9)
P 		2105.8
(2.7)
P 		743
avr 1774.6
(-1.3) 		2342.6
(3) 		1573.2
(-2.8) 		1548.9
(-3) 		1670.5
(-2.1) 		2050.2
(0.8) 		794
NetAffx Links Cluster Members
Consensus/Exemplar
Group Members
GeneChip Array Information
Probe Set ID 192169_s_at
GeneChip Array C. elegans Genome Array
Organism Common Name Nematode
Probe Design Information
Transcript ID(Array Design) affy.Ce.3786
Sequence Type Exemplar sequence
Representative Public ID K01C8.10 NCBI
Target Description K01C8.10 /REP_DB=WormBase Gene ID /WP=CE02262 /GEN=cct-4 /TR=SW:P47208 /GB=CAA88861.1 /SUBMIT=HINXTON /CHR=2 /FEA=Sanger Annotation /DEF=T-complex protein
Cluster Evidence This cluster is supported by a Sanger Annotation.
Annotation Method Description
Annotation Description This probe set was annotated using the Matching Probes based pipeline to a RefSeq identifier using 1 transcript(s).
Annotation Grade This is a grade A annotation.
Annotation Transcript Cluster (# of Matching Probes) NM_063349(11)
Transcript Assignments
Representative
Transcript		 Description Matching Probes Related Probesets by Grade
NM_063349 NCBI Caenorhabditis elegans Chaperonin Containing TCP-1 family member (cct-4) (cct-4) mRNA, complete cds. 11/11 None
SNAP00000019063 ENSEMBL cdna:SNAP chromosome:CEL140:II:8283591:8285404:1 11/11 None
GENEFINDER00000019064 ENSEMBL cdna:GeneFinder chromosome:CEL140:II:8283591:8285339:1 11/11 None
K01C8.10.4 ENSEMBL cdna:known chromosome:CEL140:II:8283582:8285625:1 gene:K01C8.10 11/11 None
K01C8.10.2 ENSEMBL cdna:known chromosome:CEL140:II:8283584:8285634:1 gene:K01C8.10 11/11 None
K01C8.10.6 ENSEMBL cdna:known chromosome:CEL140:II:8283584:8285859:1 gene:K01C8.10 11/11 None
K01C8.10.3 ENSEMBL cdna:known chromosome:CEL140:II:8283590:8285634:1 gene:K01C8.10 11/11 None
K01C8.10.1 ENSEMBL cdna:known chromosome:CEL140:II:8283591:8285634:1 gene:K01C8.10 11/11 None
K01C8.10.5 ENSEMBL cdna:known chromosome:CEL140:II:8283591:8285693:1 gene:K01C8.10 11/11 None
Annotation Notes
There are no noteworthy cross hybridizing mRNAs found for this probe set.
Genomic Alignment of Consensus/Exemplar Sequence
Assembly Wormbase March 2004
Alignment(s)
Position Identity Coverage Cytoband
chrII:8283587-8285401(+) 100.0 100.0
Public Domain and Genome References
Gene Title T-complex protein
Gene Symbol cct-4
Ensembl K01C8.10
Entrez Gene 174330 Entrez gene
SwissProt P47208 EMBL-EBI
WormBase CE02262 Wormbase
Functional Annotations
Ortholog
ID Title Organism
ATH1-121501:258152_AT chaperonin, putative at
CANINE:1604073_AT similar to T-complex protein 1, delta subunit (TCP-1-delta) (CCT-delta) (A45) cfa
CANINE_2:CFA.1588.1.S1_AT similar to T-complex protein 1, delta subunit (TCP-1-delta) (CCT-delta) (A45) cfa
CANINE_2:CFAAFFX.5572.1.S1_AT similar to T-complex protein 1, delta subunit (TCP-1-delta) (CCT-delta) (A45) cfa
CANINE_2:CFAAFFX.5572.1.S1_S_AT similar to T-complex protein 1, delta subunit (TCP-1-delta) (CCT-delta) (A45) cfa
DROSOPHILA_2:1629752_AT dm
DROSGENOME1:143000_AT dm
CHICKEN:GGA.3302.1.S1_A_AT chaperonin containing TCP1, subunit 4 (delta) gga
CHICKEN:GGAAFFX.11524.1.S1_S_AT chaperonin containing TCP1, subunit 4 (delta) gga
HG-U133_PLUS_2:200877_AT chaperonin containing TCP1, subunit 4 (delta) hs
HG-U133A_2:200877_AT chaperonin containing TCP1, subunit 4 (delta) hs
HG-U133A:200877_AT chaperonin containing TCP1, subunit 4 (delta) hs
HG-FOCUS:200877_AT chaperonin containing TCP1, subunit 4 (delta) hs
HG-U95AV2:32594_AT chaperonin containing TCP1, subunit 4 (delta) hs
HU35KSUBD:RC_R37755_S_AT chaperonin containing TCP1, subunit 4 (delta) hs
HUGENEFL:U38846_AT chaperonin containing TCP1, subunit 4 (delta) hs
U133_X3P:G5453604_3P_S_AT chaperonin containing TCP1, subunit 4 (delta) hs
HG-U95D:69637_R_AT Chaperonin containing TCP1, subunit 4 (delta) hs
HG-U95D:72253_AT Chaperonin containing TCP1, subunit 4 (delta) hs
HU35KSUBA:N35467_AT Chaperonin containing TCP1, subunit 4 (delta) hs
MOE430A:1415867_AT chaperonin subunit 4 (delta) mm
MOUSE430_2:1415867_AT chaperonin subunit 4 (delta) mm
MOUSE430A_2:1415867_AT chaperonin subunit 4 (delta) mm
MOUSE430_2:1456572_X_AT chaperonin subunit 4 (delta) mm
MOE430A:1456572_X_AT chaperonin subunit 4 (delta) mm
MOUSE430A_2:1456572_X_AT chaperonin subunit 4 (delta) mm
MOUSE430_2:1430034_AT chaperonin subunit 4 (delta) mm
MOE430B:1430034_AT chaperonin subunit 4 (delta) mm
MOE430A:1415868_AT chaperonin subunit 4 (delta) mm
MOUSE430A_2:1415868_AT chaperonin subunit 4 (delta) mm
MOUSE430_2:1415868_AT chaperonin subunit 4 (delta) mm
MOUSE430A_2:1438560_X_AT chaperonin subunit 4 (delta) mm
MOE430A:1438560_X_AT chaperonin subunit 4 (delta) mm
MOUSE430_2:1438560_X_AT chaperonin subunit 4 (delta) mm
MU11KSUBA:L25913_F_AT chaperonin subunit 4 (delta) mm
MU11KSUBB:MSA.534.0_F_AT chaperonin subunit 4 (delta) mm
MG-U74AV2:101011_AT chaperonin subunit 4 (delta) mm
MOE430A:1433447_X_AT chaperonin subunit 4 (delta) mm
MOUSE430A_2:1433447_X_AT chaperonin subunit 4 (delta) mm
MOUSE430_2:1433447_X_AT chaperonin subunit 4 (delta) mm
MOE430A:1456082_X_AT chaperonin subunit 4 (delta) mm
MOUSE430A_2:1456082_X_AT chaperonin subunit 4 (delta) mm
MOUSE430_2:1456082_X_AT chaperonin subunit 4 (delta) mm
MG-U74BV2:115988_AT chaperonin subunit 4 (delta) mm
MG-U74AV2:101687_R_AT Chaperonin subunit 4 (delta) (Cct4), mRNA mm
MOE430B:1442569_AT Chaperonin subunit 4 (delta) (Cct4), mRNA mm
MOUSE430_2:1442569_AT Chaperonin subunit 4 (delta) (Cct4), mRNA mm
MU19KSUBA:TC24484_S_AT Chaperonin subunit 4 (delta) (Cct4), mRNA mm
MU19KSUBB:TC33395_F_AT Chaperonin subunit 4 (delta) (Cct4), mRNA mm
MU11KSUBA:C79518_RC_AT Chaperonin subunit 4 (delta) (Cct4), mRNA mm
RG-U34B:RC_AA899051_S_AT chaperonin subunit 4 (delta) rn
RG-U34C:RC_AI177482_AT chaperonin subunit 4 (delta) rn
RAE230A:1371656_AT chaperonin subunit 4 (delta) rn
RAT230_2:1371656_AT chaperonin subunit 4 (delta) rn
YEAST_2:1778428_AT Subunit of the cytosolic chaperonin Cct ring complex, related to Tcp1p, required for the assembly of actin and tubulins in vivo Sc
Gene Ontology
GO Biological Process (view graph)
ID Description Evidence Links
6457 protein folding inferred from sequence similarity QuickGO AmiGO
GO Molecular Function (view graph)
ID Description Evidence Links
51082 unfolded protein binding inferred from sequence similarity QuickGO AmiGO
Protein Similarities
Method ID Description E-Value
blast CAA88861 Hypothetical protein K01C8.10 [Caenorhabditis elegans] ref|NP_495750.1| Chaperonin Containing TCP-1 family member (cct-4) [Caenorhabditis elegans] sp|P47208|TCPD_CAEEL T-complex protein 1, delta subunit (TCP-1-delta) (CCT-delta) gb|AAA92842.1| CCT-4 0.0
blast CAE57680 Hypothetical protein CBG00674 [Caenorhabditis briggsae] 0.0
blast XP_623672 PREDICTED: similar to putative chaperonin containing t-complex polypeptide 1 CCT delta subunit [Apis mellifera] 0.0
Protein Domains
Database ID Description E-Value
Pfam IPR002423 EMBL-EBI Chaperonin Cpn60/TCP-1 1.0E-126
Pfam IPR002423 EMBL-EBI Chaperonin Cpn60/TCP-1 1.0E-126
Sequence
Target Sequence 
>C. ELEGANS:192169_S_AT
gaattctcggttgccgaccagttgcctctgtcgatcattttaatgctgatgcactcggat
atgctgatcttgtggaagagattccaactggaggagatggaaaggtcatcaaggtgactg
gtgttcaaaatccaggacatgctgtctctattcttcttcgtggatcaaacaagttggtgc
ttgaggaggctgacagatctatccacgatgctctttgtgtgattcgatgcctggttaaga
agaaggctttgttgccaggaggtggagctccagagatggaaatcgctgtaaaactccgaa
atctggcacaaacccaacacggagctacgcaatactgctggagagcatttgctgatgcac
ttgagctcattccatacacacttgccgaaaacgcaggattgtcaccaattcacactgtta
cggagttgagaaacaaccatgctaatggaaacagttcctatggagtaaacgtacgcaagg
gatatgtcacagatatggttgaagaagatgttgtgcagccacttcttgttacagcatcag
ct

BLASTn GenBank NR
Probe Info
Probe Sequence(5'-3') Probe X Probe Y Probe Interrogation
Position 		Strandedness
GAATTCTCGGTTGCCGACCAGTTGC 250 323 1025 Antisense
AGTTGCCTCTGTCGATCATTTTAAT 375 63 1044 Antisense
GATGCACTCGGATATGCTGATCTTG 432 413 1072 Antisense
AGGACATGCTGTCTCTATTCTTCTT 482 55 1158 Antisense
GTTGGTGCTTGAGGAGGCTGACAGA 307 437 1197 Antisense
ACAGATCTATCCACGATGCTCTTTG 165 109 1217 Antisense
GCTCTTTGTGTGATTCGATGCCTGG 184 301 1234 Antisense
AACCCAACACGGAGCTACGCAATAC 99 97 1335 Antisense
TTCCATACACACTTGCCGAAAACGC 90 701 1394 Antisense
GAAGATGTTGTGCAGCCACTTCTTG 686 335 1528 Antisense
GCCACTTCTTGTTACAGCATCAGCT 382 279 1542 Antisense
Sequence Source Affymetrix Proprietary Database