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[192166_s_at] homeobox protein

Description C10G8.6 /REP_DB=WormBase Gene ID /WP=CE20496 /GEN=ceh-34 /TR=SW:Q94165 /GB=AAB09173.2 /SUBMIT=ST.LOUIS /CHR=5 /FEA=Sanger Annotation /DEF=homeobox protein
Cluster 6grp_highest_10_10 > 31      6grp_high1_10_10 > 03      4grp_highest_8_8 > 57      4grp_high_8_8 > 34      6grp_highest_nonorm > 60      6grp_total > 24      4grp_total > 45      6grp_highest_sub > De      6grp_cgc > 31      6grp_high1_sub > De      6grp_cgc_sub > De      6grp_total_sub > Decrease      6grp_rule_based > S1      4grp_rule_based > L1      

Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 370
1 2 3 4 range
A 548.5
(3)
P 		448.7
(0.4)
P 		316.1
(-3)
P 		329.5
(-2.7)
P 		232
B 549.2
(3)
P 		412.3
(-0.2)
P 		299.4
(-2.9)
P 		295
(-3)
P 		254
C 641.5
(3)
P 		470.9
(0.2)
P 		339.3
(-1.9)
P 		271.3
(-3)
P 		370
avr 579.7
(3) 		444
(0.1) 		318.3
(-2.6) 		298.6
(-3) 		281

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 409
1 2 3 4 5 6 range
A 563.8
(3)
P 		529.7
(2.4)
P 		253.9
(-2.1)
P 		296.8
(-1.4)
P 		197.9
(-3)
P 		243.6
(-2.3)
P 		366
B 499.6
(3)
P 		415.8
(1.5)
P 		343.1
(0.3)
P 		239.2
(-1.5)
P 		154.9
(-3)
P 		166.6
(-2.8)
P 		345
C 526.8
(3)
P 		402.3
(0.8)
P 		448.1
(1.6)
P 		309.8
(-0.9)
P 		196.3
(-2.9)
P 		191.2
(-3)
P 		336
avr 530.1
(3) 		449.3
(1.6) 		348.4
(-0.1) 		281.9
(-1.3) 		183
(-3) 		200.5
(-2.7) 		347
No Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 167
1 2 3 4 range
A 199.7
(3)
P 		97.4
(-1.1)
P 		82.6
(-1.6)
P 		48.2
(-3)
P 		152
B 175.1
(3)
P 		101.8
(-0.9)
P 		69.4
(-2.7)
P 		62.9
(-3)
P 		112
C 212.4
(3)
P 		135.4
(0.2)
P 		118.3
(-0.4)
P 		45.7
(-3)
P 		167
avr 195.7
(3) 		111.5
(-0.5) 		90.1
(-1.4) 		52.3
(-3) 		143

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 140
1 2 3 4 5 6 range
A 103.9
(-0.8)
P 		188.4
(3)
P 		55.3
(-3)
P 		75.3
(-2.1)
P 		59.7
(-2.8)
P 		59.3
(-2.8)
P 		133
B 173.8
(3)
P 		138.4
(1.1)
P 		83.3
(-1.9)
P 		63.4
(-2.9)
P 		62.9
(-3)
P 		62.1
(-3)
P 		112
C 195.3
(3)
P 		122.7
(-0.3)
P 		114
(-0.7)
P 		62.3
(-3)
P 		63.5
(-2.9)
P 		64
(-2.9)
P 		133
avr 157.7
(3) 		149.8
(2.5) 		84.2
(-1.6) 		67
(-2.7) 		62
(-3) 		61.8
(-3) 		96
NetAffx Links Cluster Members
Consensus/Exemplar
Group Members
GeneChip Array Information
Probe Set ID 192166_s_at
GeneChip Array C. elegans Genome Array
Organism Common Name Nematode
Probe Design Information
Transcript ID(Array Design) affy.Ce.11448
Sequence Type Exemplar sequence
Representative Public ID C10G8.6 NCBI
Target Description C10G8.6 /REP_DB=WormBase Gene ID /WP=CE20496 /GEN=ceh-34 /TR=SW:Q94165 /GB=AAB09173.2 /SUBMIT=ST.LOUIS /CHR=5 /FEA=Sanger Annotation /DEF=homeobox protein
Cluster Evidence This cluster is supported by a Sanger Annotation.
Annotation Method Description
Annotation Description This probe set was annotated using the Matching Probes based pipeline to a RefSeq identifier using 1 transcript(s).
Annotation Grade This is a grade A annotation.
Annotation Transcript Cluster (# of Matching Probes) NM_072018(11)
Transcript Assignments
Representative
Transcript		 Description Matching Probes Related Probesets by Grade
NM_072018 NCBI Caenorhabditis elegans C.Elegans Homeobox family member (ceh-34) (ceh-34) mRNA, complete cds. 11/11 None
SNAP00000038003 ENSEMBL cdna:SNAP chromosome:CEL140:V:5315506:5317330:-1 10/11 None
C10G8.6 ENSEMBL cdna:known chromosome:CEL140:V:5315506:5319363:-1 gene:C10G8.6 11/11 None
Annotation Notes
Cross Hybridizing mRNA Matched Probes Nature of Assignment Related Probesets by Grade
GENEFINDER00000038009 6/11 Cross Hyb Matching Probes None
Genomic Alignment of Consensus/Exemplar Sequence
Assembly Wormbase March 2004
Alignment(s)
Position Identity Coverage Cytoband
chrV:5315505-5319248(-) 100.0 100.0
Public Domain and Genome References
Gene Title homeobox protein
Gene Symbol ceh-34
Ensembl C10G8.6
Entrez Gene 178919 Entrez gene
SwissProt Q94165 EMBL-EBI
WormBase CE20496 Wormbase
Functional Annotations
Gene Ontology
GO Biological Process (view graph)
ID Description Evidence Links
6355 regulation of transcription, DNA-dependent inferred from electronic annotation QuickGO AmiGO
GO Cellular Component (view graph)
ID Description Evidence Links
5634 nucleus inferred from electronic annotation QuickGO AmiGO
GO Molecular Function (view graph)
ID Description Evidence Links
3677 DNA binding inferred from electronic annotation QuickGO AmiGO
3700 transcription factor activity inferred from electronic annotation QuickGO AmiGO
Protein Similarities
Method ID Description E-Value
blast AAB09173 C.elegans homeobox protein 34 [Caenorhabditis elegans] ref|NP_504419.1| C.Elegans Homeobox family member (ceh-34) [Caenorhabditis elegans] sp|Q94165|HM34_CAEEL Homeobox protein ceh-34 1.0E-141
blast F89046 protein C10G8.6 [imported] - Caenorhabditis elegans 1.0E-134
blast CAE62635 Hypothetical protein CBG06765 [Caenorhabditis briggsae] 1.0E-120
blast AAB09173 C.elegans homeobox protein 34 [Caenorhabditis elegans] ref|NP_504419.1| C.Elegans Homeobox family member (ceh-34) [Caenorhabditis elegans] sp|Q94165|HM34_CAEEL Homeobox protein ceh-34 1.0E-108
blast F89046 protein C10G8.6 [imported] - Caenorhabditis elegans 1.0E-108
blast CAE62635 Hypothetical protein CBG06765 [Caenorhabditis briggsae] 4.0E-90
Protein Domains
Database ID Description E-Value
scop a.4.1.Homeodomain All alpha proteins; DNA/RNA-binding 3-helical bundle; Homeodomain-like; Homeodomain 9.99999997475243E-7
scop a.4.1.Homeodomain All alpha proteins; DNA/RNA-binding 3-helical bundle; Homeodomain-like; Homeodomain 1.99999999495049E-6
Pfam IPR001356 EMBL-EBI Homeobox 4.7E-9
Pfam IPR001356 EMBL-EBI Homeobox 4.7E-9
Sequence
Target Sequence 
>C. ELEGANS:192166_S_AT
aaccttccacaatgctaccaagtaatggaatcagttttaaaagcacaagctcttgtgtat
tttacaacacaaaactggaagatgctctacaagttactggaatgcagcaagttttcccca
cataatcacacagttctacaaaatttgtggcttgatgcacattataaagaggctgcgaaa
acaaaggatcgggagctaggagcggtttgcaaataccggatccgaaagaagaacccattt
ccaaacacaatttgggatggagaagagacaaattattgctttaagtcgaaatctcgaaat
gttcttcgggatgcttacaagaaatgccagtacccatcagtagaagataaaagacgatta
gctcaacaaactgaattatcaattattcaagtgtccaactggttcaaaaacaagaggcaa
cgtgagagggcagctggtcaactcgatagaagctccgccagatccaacgacagtgacgat
ggatcatctggctgtgaatcaaaacctccgatgaatattgacagccctgcgcctccgcca
ttaccaacttcatttgatctacaaccctattatccatcaccttacacatttgct

BLASTn GenBank NR
Probe Info
Probe Sequence(5'-3') Probe X Probe Y Probe Interrogation
Position 		Strandedness
AACCTTCCACAATGCTACCAAGTAA 435 145 154 Antisense
TGGAATGCAGCAAGTTTTCCCCACA 598 545 251 Antisense
TTTCCCCACATAATCACACAGTTCT 672 669 266 Antisense
GAAATGCCAGTACCCATCAGTAGAA 262 361 474 Antisense
GTGAGAGGGCAGCTGGTCAACTCGA 460 481 575 Antisense
GGTCAACTCGATAGAAGCTCCGCCA 347 501 589 Antisense
CCGCCAGATCCAACGACAGTGACGA 670 261 608 Antisense
CGATGAATATTGACAGCCCTGCGCC 1 249 662 Antisense
TCCGCCATTACCAACTTCATTTGAT 519 595 687 Antisense
GATCTACAACCCTATTATCCATCAC 580 419 709 Antisense
TTATCCATCACCTTACACATTTGCT 25 681 723 Antisense
Sequence Source Affymetrix Proprietary Database