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[192165_s_at] serine/threonine-protein kinase

Description K11C4.1 /REP_DB=WormBase Gene ID /WP=CE12108 /TR=Q94277 /GB=AAB18314.1 /SUBMIT=ST.LOUIS /CHR=5 /FEA=Sanger Annotation /DEF=serine-threonine-protein kinase
Cluster 6grp_total > 87      4grp_total > 24      6grp_total_sub > Increase      6grp_rule_based > S6      

Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 39
1 2 3 4 range
A 37
(3)
A 		28.1
(-3)
A 		31.2
(-0.9)
A 		34.8
(1.5)
A 		9
B 3.6
(-3)
A 		19.8
(1.6)
A 		24.6
(3)
A 		12
(-0.6)
A 		21
C 2.9
(-3)
A 		2.7
(-3)
A 		12.7
(-1.4)
A 		41.3
(3)
A 		39
avr 14.5
(-3) 		16.9
(-2) 		22.8
(0.3) 		29.4
(3) 		15

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 168
1 2 3 4 5 6 range
A 4
(-3)
A 		19.5
(-2.4)
A 		17.5
(-2.5)
A 		46.4
(-1.5)
P 		75.8
(-0.4)
P 		168.9
(3)
P 		165
B 9.2
(-2.7)
A 		2.5
(-3)
A 		20.2
(-2.2)
A 		33.3
(-1.6)
A 		55.5
(-0.5)
P 		131.1
(3)
P 		129
C 1.4
(-3)
A 		5.5
(-2.8)
A 		2.8
(-2.9)
A 		1.6
(-3)
A 		68.9
(-0)
P 		136.6
(3)
P 		135
avr 4.9
(-3) 		9.2
(-2.8) 		13.5
(-2.6) 		27.1
(-2.1) 		66.7
(-0.4) 		145.5
(3) 		141
No Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 13
1 2 3 4 range
A 13.5
(3)
A 		6.1
(-2.3)
A 		8.2
(-0.8)
A 		5.1
(-3)
A 		8
B 1.1
(-3)
A 		4.9
(2)
A 		5.7
(3)
A 		2.6
(-1)
A 		5
C 1
(-2.8)
A 		0.8
(-3)
A 		4.4
(0.5)
A 		7
(3)
A 		6
avr 5.2
(0.5) 		3.9
(-3) 		6.1
(3) 		4.9
(-0.3) 		2

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 49
1 2 3 4 5 6 range
A 0.7
(-3)
A 		6.9
(-2.1)
A 		3.8
(-2.5)
A 		11.8
(-1.4)
P 		22.9
(0.3)
P 		41.1
(3)
P 		40
B 3.2
(-2.7)
A 		0.8
(-3)
A 		4.9
(-2.5)
A 		8.8
(-2)
A 		22.5
(-0.3)
P 		48.9
(3)
P 		48
C 0.5
(-3)
A 		1.7
(-2.8)
A 		0.7
(-2.9)
A 		0.3
(-3)
A 		22.3
(-0.1)
P 		45.7
(3)
P 		45
avr 1.5
(-3) 		3.1
(-2.8) 		3.1
(-2.8) 		7
(-2.2) 		22.6
(-0.1) 		45.2
(3) 		44
NetAffx Links Cluster Members
Consensus/Exemplar
Group Members
GeneChip Array Information
Probe Set ID 192165_s_at
GeneChip Array C. elegans Genome Array
Organism Common Name Nematode
Probe Design Information
Transcript ID(Array Design) affy.Ce.11447
Sequence Type Exemplar sequence
Representative Public ID K11C4.1 NCBI
Target Description K11C4.1 /REP_DB=WormBase Gene ID /WP=CE12108 /TR=Q94277 /GB=AAB18314.1 /SUBMIT=ST.LOUIS /CHR=5 /FEA=Sanger Annotation /DEF=serine-threonine-protein kinase
Cluster Evidence This cluster is supported by a Sanger Annotation.
Annotation Method Description
Annotation Description This probe set was annotated using the Matching Probes based pipeline to a RefSeq identifier using 1 transcript(s).
Annotation Grade This is a grade A annotation.
Annotation Transcript Cluster (# of Matching Probes) NM_072350(11)
Transcript Assignments
Representative
Transcript		 Description Matching Probes Related Probesets by Grade
NM_072350 NCBI Caenorhabditis elegans K11C4.1 (K11C4.1) mRNA, complete cds. 11/11 A 
SNAP00000040595 ENSEMBL cdna:SNAP chromosome:CEL140:V:6900719:6901049:1 9/11 None
GENEFINDER00000040640 ENSEMBL cdna:GeneFinder chromosome:CEL140:V:6899618:6901049:1 11/11 None
K11C4.1 ENSEMBL cdna:known chromosome:CEL140:V:6899618:6901049:1 gene:K11C4.1 11/11 A 
Annotation Notes
There are no noteworthy cross hybridizing mRNAs found for this probe set.
Genomic Alignment of Consensus/Exemplar Sequence
Assembly Wormbase March 2004
Alignment(s)
Position Identity Coverage Cytoband
chrV:6899618-6901050(+) 100.0 100.0
Public Domain and Genome References
Gene Title serine/threonine-protein kinase
Ensembl K11C4.1
Entrez Gene 179078 Entrez gene
SwissProt Q94277 EMBL-EBI
WormBase CE12108 Wormbase
Functional Annotations
Gene Ontology
GO Biological Process (view graph)
ID Description Evidence Links
6468 protein amino acid phosphorylation inferred from electronic annotation QuickGO AmiGO
GO Molecular Function (view graph)
ID Description Evidence Links
4672 protein kinase activity inferred from electronic annotation QuickGO AmiGO
4674 protein serine/threonine kinase activity inferred from electronic annotation QuickGO AmiGO
5524 ATP binding inferred from electronic annotation QuickGO AmiGO
Protein Similarities
Method ID Description E-Value
blast AAB18314 Hypothetical protein K11C4.1 [Caenorhabditis elegans] ref|NP_504751.1| K11C4.1 [Caenorhabditis elegans] 1.0E-180
blast CAE67695 Hypothetical protein CBG13263 [Caenorhabditis briggsae] 1.0E-150
blast CAE64559 Hypothetical protein CBG09309 [Caenorhabditis briggsae] 1.0E-149
blast AAB18314 Hypothetical protein K11C4.1 [Caenorhabditis elegans] ref|NP_504751.1| K11C4.1 [Caenorhabditis elegans] 6.0E-50
Protein Domains
Database ID Description E-Value
Pfam IPR000719 EMBL-EBI Protein kinase 1.1E-11
Sequence
Target Sequence 
>C. ELEGANS:192165_S_AT
gatgacgtcgaaagctggttctatatgctcgtcgactttaccaatgcagctcttccttgg
aaagttgtgaatgagatcccacaggttggtgaaatgaagaagaactctcgttttgatcca
ctcgtgactcaattattggctggatgtccggtagatgagtatcgcctgatcatgaaccat
atcgatggtctttcattcttcatggagccc

BLASTn GenBank NR
Probe Info
Probe Sequence(5'-3') Probe X Probe Y Probe Interrogation
Position 		Strandedness
GATGACGTCGAAAGCTGGTTCTATA 385 411 631 Antisense
AGCTGGTTCTATATGCTCGTCGACT 585 79 643 Antisense
TGCTCGTCGACTTTACCAATGCAGC 371 579 656 Antisense
GAATGAGATCCCACAGGTTGGTGAA 45 331 699 Antisense
AGAAGAACTCTCGTTTTGATCCACT 574 73 728 Antisense
GTTTTGATCCACTCGTGACTCAATT 35 449 740 Antisense
TCAATTATTGGCTGGATGTCCGGTA 465 629 759 Antisense
ATGTCCGGTAGATGAGTATCGCCTG 487 47 774 Antisense
GTATCGCCTGATCATGAACCATATC 19 455 789 Antisense
CCATATCGATGGTCTTTCATTCTTC 354 271 807 Antisense
TGGTCTTTCATTCTTCATGGAGCCC 248 553 816 Antisense
Sequence Source Affymetrix Proprietary Database