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[192151_at] human 100 kDa activator protein

Description F10G7.2 /REP_DB=WormBase Gene ID /WP=CE02626 /TR=Q19328 /GB=AAA81130.1 /SUBMIT=ST.LOUIS /CHR=2 /FEA=Sanger Annotation /DEF=human 100 kDa activator protein
Cluster 6grp_highest_10_10 > 10      6grp_high1_10_10 > 14      4grp_highest_8_8 > 09      4grp_high_8_8 > 53      6grp_highest_nonorm > 70      6grp_total > 04      4grp_total > 58      6grp_cgc > 41      4grp_rule_based > L3      

Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 404
1 2 3 4 range
A 377.4
(-1.1)
P 		618.6
(3)
P 		608.7
(2.8)
P 		263
(-3)
P 		356
B 420.3
(0.5)
P 		537.9
(2.5)
P 		569
(3)
P 		214.5
(-3)
P 		355
C 321.9
(-1.8)
P 		595.4
(3)
P 		578
(2.7)
P 		250.9
(-3)
P 		345
avr 373.2
(-0.7) 		584
(3) 		585.2
(3) 		242.8
(-3) 		342

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 252
1 2 3 4 5 6 range
A 428.4
(3)
P 		322.1
(0.5)
P 		267.1
(-0.8)
P 		259.1
(-1)
P 		303.2
(0)
P 		176.5
(-3)
P 		252
B 409.6
(3)
P 		349.3
(1.3)
P 		232
(-2.1)
P 		346.9
(1.2)
P 		235
(-2)
P 		200.1
(-3)
P 		210
C 304
(1.6)
P 		337.7
(3)
P 		304
(1.6)
P 		305.1
(1.6)
P 		231.5
(-1.5)
P 		197.4
(-3)
P 		140
avr 380.7
(3) 		336.4
(1.6) 		267.7
(-0.6) 		303.7
(0.6) 		256.6
(-0.9) 		191.3
(-3) 		189
No Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 163
1 2 3 4 range
A 137.4
(1.9)
P 		134.3
(1.8)
P 		159.1
(3)
P 		38.5
(-3)
P 		121
B 134
(3)
P 		132.9
(2.9)
P 		131.8
(2.9)
P 		45.7
(-3)
P 		88
C 106.6
(-0.6)
P 		171.2
(1.9)
P 		201.5
(3)
P 		42.3
(-3)
P 		159
avr 126
(1.1) 		146.1
(2.1) 		164.1
(3) 		42.2
(-3) 		122

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 100
1 2 3 4 5 6 range
A 79
(0)
P 		114.6
(3)
P 		58.2
(-1.7)
P 		65.7
(-1.1)
P 		91.5
(1.1)
P 		43
(-3)
P 		72
B 142.5
(3)
P 		116.3
(1.2)
P 		56.3
(-3)
P 		91.9
(-0.5)
P 		95.5
(-0.3)
P 		74.6
(-1.7)
P 		86
C 112.7
(3)
P 		103
(1.9)
P 		77.4
(-1.1)
P 		61.4
(-3)
P 		74.9
(-1.4)
P 		66.1
(-2.5)
P 		51
avr 111.4
(3) 		111.3
(3) 		64
(-2.7) 		73
(-1.6) 		87.3
(0.1) 		61.2
(-3) 		50
NetAffx Links Cluster Members
Consensus/Exemplar
GeneChip Array Information
Probe Set ID 192151_at
GeneChip Array C. elegans Genome Array
Organism Common Name Nematode
Probe Design Information
Transcript ID(Array Design) affy.Ce.4662
Sequence Type Exemplar sequence
Representative Public ID F10G7.2 NCBI
Target Description F10G7.2 /REP_DB=WormBase Gene ID /WP=CE02626 /TR=Q19328 /GB=AAA81130.1 /SUBMIT=ST.LOUIS /CHR=2 /FEA=Sanger Annotation /DEF=human 100 kDa activator protein
Cluster Evidence This cluster is supported by a Sanger Annotation.
Annotation Method Description
Annotation Description This probe set was annotated using the Matching Probes based pipeline to a RefSeq identifier using 1 transcript(s).
Annotation Grade This is a grade A annotation.
Annotation Transcript Cluster (# of Matching Probes) NM_062438(11)
Transcript Assignments
Representative
Transcript		 Description Matching Probes Related Probesets by Grade
NM_062438 NCBI Caenorhabditis elegans Tudor Staphylococcal Nuclease homolog family member (tsn-1) (tsn-1) mRNA, complete cds. 11/11 None
SNAP00000005197 ENSEMBL cdna:SNAP chromosome:CEL140:II:4706831:4709761:1 11/11 None
GENEFINDER00000005215 ENSEMBL cdna:GeneFinder chromosome:CEL140:II:4706831:4709761:1 11/11 None
F10G7.2.3 ENSEMBL cdna:known chromosome:CEL140:II:4706800:4710148:1 gene:F10G7.2 11/11 None
F10G7.2.2 ENSEMBL cdna:known chromosome:CEL140:II:4706800:4710148:1 gene:F10G7.2 11/11 None
F10G7.2.1 ENSEMBL cdna:known chromosome:CEL140:II:4706808:4710148:1 gene:F10G7.2 11/11 None
Annotation Notes
There are no noteworthy cross hybridizing mRNAs found for this probe set.
Genomic Alignment of Consensus/Exemplar Sequence
Assembly Wormbase March 2004
Alignment(s)
Position Identity Coverage Cytoband
chrII:4706829-4709760(+) 100.0 100.0
Public Domain and Genome References
Gene Title human 100 kDa activator protein
Gene Symbol tsn-1
Ensembl F10G7.2
Entrez Gene 173811 Entrez gene
SwissProt Q19328 EMBL-EBI
WormBase CE02626 Wormbase
Functional Annotations
Ortholog
ID Title Organism
ATH1-121501:250626_AT tudor domain-containing protein / nuclease family protein at
CANINE:1595173_AT similar to Staphylococcal nuclease domain containing protein 1 (p100 co-activator) (100 kDa coactivator) (EBNA2 coactivator p100) cfa
CANINE:1594188_S_AT similar to Staphylococcal nuclease domain containing protein 1 (p100 co-activator) (100 kDa coactivator) (EBNA2 coactivator p100) cfa
CANINE_2:CFA.21606.1.S1_S_AT similar to Staphylococcal nuclease domain containing protein 1 (p100 co-activator) (100 kDa coactivator) (EBNA2 coactivator p100) cfa
CANINE_2:CFA.7948.1.A1_A_AT similar to Staphylococcal nuclease domain containing protein 1 (p100 co-activator) (100 kDa coactivator) (EBNA2 coactivator p100) cfa
CANINE_2:CFA.7948.2.A1_A_AT similar to Staphylococcal nuclease domain containing protein 1 (p100 co-activator) (100 kDa coactivator) (EBNA2 coactivator p100) cfa
CANINE_2:CFA.7948.2.A1_S_AT similar to Staphylococcal nuclease domain containing protein 1 (p100 co-activator) (100 kDa coactivator) (EBNA2 coactivator p100) cfa
DROSOPHILA_2:1640241_AT dm
DROSGENOME1:153578_AT dm
HU35KSUBD:RC_AA429621_AT staphylococcal nuclease domain containing 1 hs
HUGENEFL:U22055_AT staphylococcal nuclease domain containing 1 hs
HG-U133A:201622_AT staphylococcal nuclease domain containing 1 hs
HG-U133_PLUS_2:201622_AT staphylococcal nuclease domain containing 1 hs
HG-FOCUS:201622_AT staphylococcal nuclease domain containing 1 hs
HG-U133A_2:201622_AT staphylococcal nuclease domain containing 1 hs
U133_X3P:G7657430_3P_X_AT staphylococcal nuclease domain containing 1 hs
U133_X3P:G7657430_3P_AT staphylococcal nuclease domain containing 1 hs
HG-U95AV2:37730_AT staphylococcal nuclease domain containing 1 hs
HU35KSUBB:RC_H08778_AT Staphylococcal nuclease domain containing 1 hs
HU35KSUBC:RC_AA405838_AT Staphylococcal nuclease domain containing 1 hs
U133_X3P:HS.40507.0.A1_3P_AT Staphylococcal nuclease domain containing 1 hs
U133_X3P:HS.189282.0.S1_3P_AT Staphylococcal nuclease domain containing 1 hs
U133_X3P:HS.133521.0.A1_3P_AT Staphylococcal nuclease domain containing 1 hs
HG-U133_PLUS_2:228271_AT Staphylococcal nuclease domain containing 1 hs
HG-U133B:228271_AT Staphylococcal nuclease domain containing 1 hs
HG-U133_PLUS_2:232525_AT Staphylococcal nuclease domain containing 1 hs
HG-U133B:232525_AT Staphylococcal nuclease domain containing 1 hs
HG-U133_PLUS_2:242506_AT Staphylococcal nuclease domain containing 1 hs
HG-U133B:242506_AT Staphylococcal nuclease domain containing 1 hs
HG-U95B:47495_AT Staphylococcal nuclease domain containing 1 hs
HG-U95B:50992_AT Staphylococcal nuclease domain containing 1 hs
HG-U95E:68045_AT Staphylococcal nuclease domain containing 1 hs
HG-U133_PLUS_2:243486_AT Staphylococcal nuclease domain containing 1 hs
HG-U133B:243486_AT Staphylococcal nuclease domain containing 1 hs
HG-U133_PLUS_2:244218_AT Staphylococcal nuclease domain containing 1 hs
HG-U133B:244218_AT Staphylococcal nuclease domain containing 1 hs
HG-U95B:51400_AT Staphylococcal nuclease domain containing 1 hs
HG-U95C:65200_AT Staphylococcal nuclease domain containing 1 hs
HG-U95E:70439_AT Staphylococcal nuclease domain containing 1 hs
HG-U95D:71589_R_AT Staphylococcal nuclease domain containing 1 hs
HG-U95D:71599_AT Staphylococcal nuclease domain containing 1 hs
HG-U95D:76498_AT Staphylococcal nuclease domain containing 1 hs
HG-U95D:78498_AT Staphylococcal nuclease domain containing 1 hs
HG-U95D:86346_AT Staphylococcal nuclease domain containing 1 hs
U133_X3P:HS.122523.0.S1_3P_AT Staphylococcal nuclease domain containing 1 hs
HU35KSUBB:RC_R12581_AT Staphylococcal nuclease domain containing 1 hs
HU35KSUBD:RC_N58185_AT Staphylococcal nuclease domain containing 1 hs
U133_X3P:HS.133552.0.A1_3P_AT Staphylococcal nuclease domain containing 1 hs
MOUSE430A_2:1416038_AT expressed sequence AL033314 mm
MOUSE430_2:1416038_AT expressed sequence AL033314 mm
MOE430A:1416038_AT expressed sequence AL033314 mm
MU11KSUBA:AA244816_S_AT expressed sequence AL033314 mm
MG-U74AV2:96260_AT expressed sequence AL033314 mm
MOE430A:1437037_X_AT expressed sequence AL033314 mm
MOUSE430A_2:1437037_X_AT expressed sequence AL033314 mm
MOUSE430_2:1437037_X_AT expressed sequence AL033314 mm
MG-U74CV2:137340_AT Expressed sequence AL033314, mRNA (cDNA clone MGC:5677 IMAGE:3592548) mm
MOUSE430A_2:1437036_AT Expressed sequence AL033314, mRNA (cDNA clone MGC:5677 IMAGE:3592548) mm
MOE430A:1437036_AT Expressed sequence AL033314, mRNA (cDNA clone MGC:5677 IMAGE:3592548) mm
MOUSE430_2:1437036_AT Expressed sequence AL033314, mRNA (cDNA clone MGC:5677 IMAGE:3592548) mm
MOE430B:1441067_AT Expressed sequence AL033314, mRNA (cDNA clone MGC:5677 IMAGE:3592548) mm
MOUSE430_2:1441067_AT Expressed sequence AL033314, mRNA (cDNA clone MGC:5677 IMAGE:3592548) mm
MOE430B:1441244_AT Expressed sequence AL033314, mRNA (cDNA clone MGC:5677 IMAGE:3592548) mm
MOUSE430_2:1441244_AT Expressed sequence AL033314, mRNA (cDNA clone MGC:5677 IMAGE:3592548) mm
MOE430B:1442910_AT Expressed sequence AL033314, mRNA (cDNA clone MGC:5677 IMAGE:3592548) mm
MOUSE430_2:1442910_AT Expressed sequence AL033314, mRNA (cDNA clone MGC:5677 IMAGE:3592548) mm
MOE430B:1444538_AT Expressed sequence AL033314, mRNA (cDNA clone MGC:5677 IMAGE:3592548) mm
MOUSE430_2:1444538_AT Expressed sequence AL033314, mRNA (cDNA clone MGC:5677 IMAGE:3592548) mm
MOE430B:1447167_AT Expressed sequence AL033314, mRNA (cDNA clone MGC:5677 IMAGE:3592548) mm
MOUSE430_2:1447167_AT Expressed sequence AL033314, mRNA (cDNA clone MGC:5677 IMAGE:3592548) mm
MU19KSUBC:TC40590_AT Expressed sequence AL033314, mRNA (cDNA clone MGC:5677 IMAGE:3592548) mm
RG-U34A:U83883_G_AT staphylococcal nuclease domain containing 1 rn
RG-U34A:U83883_AT staphylococcal nuclease domain containing 1 rn
RAE230A:1367790_AT staphylococcal nuclease domain containing 1 rn
RAT230_2:1367790_AT staphylococcal nuclease domain containing 1 rn
RAE230B:1385754_S_AT Staphylococcal nuclease domain containing 1 rn
RAT230_2:1385754_S_AT Staphylococcal nuclease domain containing 1 rn
RAE230B:1386677_AT Staphylococcal nuclease domain containing 1 rn
RAT230_2:1386677_AT Staphylococcal nuclease domain containing 1 rn
Gene Ontology
GO Molecular Function (view graph)
ID Description Evidence Links
3676 nucleic acid binding inferred from electronic annotation QuickGO AmiGO
4518 nuclease activity inferred from electronic annotation QuickGO AmiGO
Protein Similarities
Method ID Description E-Value
blast NP_494839 Tudor Staphylococcal Nuclease homolog family member (tsn-1) [Caenorhabditis elegans] gb|AAA81130.1| Tudor staphylococcal nuclease homolog protein 1 [Caenorhabditis elegans] 0.0
blast CAE60646 Hypothetical protein CBG04292 [Caenorhabditis briggsae] 0.0
blast NP_001027905 4SNc-Tudor domain protein [Takifugu rubripes] dbj|BAD32626.1| 4SNc-Tudor domain protein [Takifugu rubripes] 0.0
Protein Domains
Database ID Description E-Value
Pfam IPR008191 EMBL-EBI Maternal tudor protein 6.3E-33
Pfam IPR006021 EMBL-EBI Staphylococcus nuclease (SNase-like) 8.2E-6
Pfam IPR006021 EMBL-EBI Staphylococcus nuclease (SNase-like) 3.0E-16
Pfam IPR006021 EMBL-EBI Staphylococcus nuclease (SNase-like) 8.8E-7
Pfam IPR006021 EMBL-EBI Staphylococcus nuclease (SNase-like) 2.7E-53
Pfam IPR006021 EMBL-EBI Staphylococcus nuclease (SNase-like) 1.0E-4
Sequence
Target Sequence 
>C. ELEGANS:192151_AT
tgagacaagctcttgccgaacatccaccactcgctggatcttataccaccaagcgtggag
atttgtgcgttgccaagttctctcaggatggacaatggtaccgttgcaaggtcgagagcg
ttcgtgctgggcaagcagagattgtttacattgattacggaaatcgtgagacaattgagg
ctgtcaagcttgctcaaattccagcaggatttgccaatttcccagctggagttagagaat
ataaccttgctcttgctaagcttccaaacgaggattacgtccaactcacttctgatgctt
tcgcccagtacttgtttggtcactcttcggtattcattaacagtgagtacaaggtcggaa
cttcagaatatgtaactgtttattacgacagtggaaacaagaaggtcgacatcggtaaat
ctcttattgctgagggactcgctcttgc

BLASTn GenBank NR
Probe Info
Probe Sequence(5'-3') Probe X Probe Y Probe Interrogation
Position 		Strandedness
TGAGACAAGCTCTTGCCGAACATCC 78 569 2186 Antisense
CACTCGCTGGATCTTATACCACCAA 310 197 2213 Antisense
AGATTTGTGCGTTGCCAAGTTCTCT 366 65 2244 Antisense
CAAGGTCGAGAGCGTTCGTGCTGGG 88 183 2292 Antisense
GAGGCTGTCAAGCTTGCTCAAATTC 593 405 2362 Antisense
AGCAGGATTTGCCAATTTCCCAGCT 55 79 2388 Antisense
TAACCTTGCTCTTGCTAAGCTTCCA 650 637 2427 Antisense
CGAGGATTACGTCCAACTCACTTCT 356 249 2454 Antisense
TTCGCCCAGTACTTGTTTGGTCACT 537 695 2485 Antisense
TTTGGTCACTCTTCGGTATTCATTA 194 667 2500 Antisense
TTATTGCTGAGGGACTCGCTCTTGC 272 679 2609 Antisense
Sequence Source Affymetrix Proprietary Database