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[192103_s_at] endopeptidase

Description Y110A7A.14 /REP_DB=WormBase Gene ID /WP=CE23243 /GEN=pas-3 /TR=SW:Q9N599 /GB=AAF60416.1 /SUBMIT=ST.LOUIS /CHR=1 /FEA=Sanger Annotation /DEF=endopeptidase
Cluster 6grp_highest_10_10 > 39      6grp_high1_10_10 > 82      4grp_highest_8_8 > 14      4grp_high_8_8 > 22      6grp_highest_nonorm > 36      6grp_total > 73      4grp_total > 16      6grp_highest_sub > 04      6grp_cgc > 76      6grp_high1_sub > 04      6grp_cgc_sub > 03_04      6grp_total_sub > Hat      6grp_rule_based > S4      4grp_rule_based > L4      

Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 5581
1 2 3 4 range
A 3454.9
(-3)
P 		4293.4
(-1.7)
P 		5258.7
(-0.2)
P 		7286.1
(3)
P 		3831
B 3434.2
(-3)
P 		4967.1
(-1.3)
P 		5264.5
(-1)
P 		8802.2
(3)
P 		5368
C 3221.5
(-3)
P 		4210.4
(-1.8)
P 		5228.4
(-0.6)
P 		8302.9
(3)
P 		5081
avr 3370.2
(-3) 		4490.3
(-1.6) 		5250.5
(-0.6) 		8130.4
(3) 		4760

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 2725
1 2 3 4 5 6 range
A 2711
(-3)
P 		3201.5
(-1.9)
P 		3729.3
(-0.8)
P 		5435.6
(3)
P 		3923.8
(-0.3)
P 		3435.9
(-1.4)
P 		2725
B 3005.6
(-3)
P 		3377.1
(-1.9)
P 		3570
(-1.3)
P 		4953.8
(3)
P 		4448.2
(1.4)
P 		3762
(-0.7)
P 		1948
C 3007.8
(-3)
P 		3541
(-0.3)
P 		4191.9
(3)
P 		3637.3
(0.2)
P 		3967.8
(1.9)
P 		4112.6
(2.6)
P 		1184
avr 2908.1
(-3) 		3373.2
(-1.4) 		3830.4
(0.1) 		4675.6
(3) 		4113.3
(1.1) 		3770.2
(-0.1) 		1768
No Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 944
1 2 3 4 range
A 1257.9
(1.4)
P 		932
(-3)
P 		1374.7
(3)
P 		1066.5
(-1.2)
P 		443
B 1095.1
(-3)
P 		1226.8
(-2)
P 		1219.9
(-2)
P 		1875.7
(3)
P 		781
C 1066.4
(-3)
P 		1210.5
(-1.9)
P 		1822.3
(3)
P 		1400
(-0.4)
P 		756
avr 1139.8
(-2.7) 		1123.1
(-3) 		1472.3
(3) 		1447.4
(2.6) 		349

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 1308
1 2 3 4 5 6 range
A 499.7
(-3)
P 		1138.6
(1.4)
P 		812.2
(-0.9)
P 		1378.6
(3)
P 		1184
(1.7)
P 		836.5
(-0.7)
P 		879
B 1045.8
(-1.9)
P 		1124.1
(-1.4)
P 		866.9
(-3)
P 		1312.1
(-0.2)
P 		1807.3
(3)
P 		1402.8
(0.4)
P 		940
C 1114.9
(0.6)
P 		1080.5
(0.2)
P 		1066.9
(0.1)
P 		731.5
(-3)
P 		1283.9
(2.1)
P 		1376.7
(3)
P 		645
avr 886.8
(-3) 		1114.4
(-0.5) 		915.3
(-2.7) 		1140.7
(-0.2) 		1425.1
(3) 		1205.3
(0.6) 		538
NetAffx Links Cluster Members
Consensus/Exemplar
Group Members
GeneChip Array Information
Probe Set ID 192103_s_at
GeneChip Array C. elegans Genome Array
Organism Common Name Nematode
Probe Design Information
Transcript ID(Array Design) affy.Ce.1229
Sequence Type Exemplar sequence
Representative Public ID Y110A7A.14 NCBI
Target Description Y110A7A.14 /REP_DB=WormBase Gene ID /WP=CE23243 /GEN=pas-3 /TR=SW:Q9N599 /GB=AAF60416.1 /SUBMIT=ST.LOUIS /CHR=1 /FEA=Sanger Annotation /DEF=endopeptidase
Cluster Evidence This cluster is supported by a Sanger Annotation.
Annotation Method Description
Annotation Description This probe set was annotated using the Matching Probes based pipeline to a RefSeq identifier using 1 transcript(s).
Annotation Grade This is a grade A annotation.
Annotation Transcript Cluster (# of Matching Probes) NM_059119(11)
Transcript Assignments
Representative
Transcript		 Description Matching Probes Related Probesets by Grade
NM_059119 NCBI Caenorhabditis elegans Y110A7A.14 (endopeptidase) mRNA, complete cds. 11/11 None
SNAP00000029203 ENSEMBL cdna:SNAP chromosome:CEL140:I:5105250:5106048:-1 11/11 None
GENEFINDER00000029223 ENSEMBL cdna:GeneFinder chromosome:CEL140:I:5105250:5106048:-1 11/11 None
Y110A7A.14.1 ENSEMBL cdna:known chromosome:CEL140:I:5104812:5106207:-1 gene:Y110A7A.14 11/11 None
Y110A7A.14.2 ENSEMBL cdna:known chromosome:CEL140:I:5105250:5106051:-1 gene:Y110A7A.14 11/11 None
Annotation Notes
There are no noteworthy cross hybridizing mRNAs found for this probe set.
Genomic Alignment of Consensus/Exemplar Sequence
Assembly Wormbase March 2004
Alignment(s)
Position Identity Coverage Cytoband
chrI:5105249-5106200(-) 100.0 100.0
Public Domain and Genome References
Gene Title endopeptidase
Gene Symbol pas-3
Ensembl Y110A7A.14
Entrez Gene 172139 Entrez gene
WormBase CE30307 Wormbase
Functional Annotations
Ortholog
ID Title Organism
ATH1-121501:256795_AT 20S proteasome alpha subunit C (PAC1) (PRC9) at
CANINE:1597269_S_AT similar to Proteasome subunit alpha type 4 (Proteasome component C9) (Macropain subunit C9) (Multicatalytic endopeptidase complex subunit C9) (Proteasome subunit L) cfa
CANINE:1590352_X_AT similar to Proteasome subunit alpha type 4 (Proteasome component C9) (Macropain subunit C9) (Multicatalytic endopeptidase complex subunit C9) (Proteasome subunit L) cfa
CANINE_2:CFA.10406.1.S1_AT similar to Proteasome subunit alpha type 4 (Proteasome component C9) (Macropain subunit C9) (Multicatalytic endopeptidase complex subunit C9) (Proteasome subunit L) cfa
CANINE_2:CFAAFFX.3522.1.S1_S_AT similar to Proteasome subunit alpha type 4 (Proteasome component C9) (Macropain subunit C9) (Multicatalytic endopeptidase complex subunit C9) (Proteasome subunit L) cfa
DROSOPHILA_2:1634820_AT Proteasome 29kD subunit dm
DROSGENOME1:143313_AT Proteasome 29kD subunit dm
CHICKEN:GGA.4858.1.S1_AT proteasome (prosome, macropain) subunit, alpha type, 4 gga
HG-U95AV2:1449_AT proteasome (prosome, macropain) subunit, alpha type, 4 hs
HC-G110:1449_AT proteasome (prosome, macropain) subunit, alpha type, 4 hs
HUGENEFL:D00763_AT proteasome (prosome, macropain) subunit, alpha type, 4 hs
HG-U133_PLUS_2:203396_AT proteasome (prosome, macropain) subunit, alpha type, 4 hs
HG-U133A:203396_AT proteasome (prosome, macropain) subunit, alpha type, 4 hs
HG-FOCUS:203396_AT proteasome (prosome, macropain) subunit, alpha type, 4 hs
HG-U133A_2:203396_AT proteasome (prosome, macropain) subunit, alpha type, 4 hs
HU35KSUBD:RC_AA206497_S_AT proteasome (prosome, macropain) subunit, alpha type, 4 hs
HG-U95AV2:1450_G_AT proteasome (prosome, macropain) subunit, alpha type, 4 hs
HC-G110:1450_G_AT proteasome (prosome, macropain) subunit, alpha type, 4 hs
U133_X3P:G4506184_3P_AT proteasome (prosome, macropain) subunit, alpha type, 4 hs
MU11KSUBA:AA107734_F_AT proteasome (prosome, macropain) subunit, alpha type 4 mm
MU11KSUBA:AA008321_S_AT proteasome (prosome, macropain) subunit, alpha type 4 mm
MG-U74AV2:97459_AT proteasome (prosome, macropain) subunit, alpha type 4 mm
MG-U74CV2:170225_F_AT proteasome (prosome, macropain) subunit, alpha type 4 mm
MOE430A:1460339_AT proteasome (prosome, macropain) subunit, alpha type 4 mm
MOUSE430A_2:1460339_AT proteasome (prosome, macropain) subunit, alpha type 4 mm
MOUSE430_2:1460339_AT proteasome (prosome, macropain) subunit, alpha type 4 mm
MU19KSUBB:TC33979_AT Proteasome (prosome, macropain) subunit, alpha type 4, mRNA (cDNA clone MGC:5640 IMAGE:3592024) mm
MU19KSUBB:TC33980_AT Proteasome (prosome, macropain) subunit, alpha type 4, mRNA (cDNA clone MGC:5640 IMAGE:3592024) mm
RG-U34A:X55986MRNA_S_AT proteasome (prosome, macropain) subunit, alpha type 4 rn
RAE230A:1367837_AT proteasome (prosome, macropain) subunit, alpha type 4 rn
RAT230_2:1367837_AT proteasome (prosome, macropain) subunit, alpha type 4 rn
YEAST_2:1775007_AT 20S proteasome beta-type subunit; the only nonessential 20S subunit Sc
Gene Ontology
GO Biological Process (view graph)
ID Description Evidence Links
6511 ubiquitin-dependent protein catabolism inferred from electronic annotation QuickGO AmiGO
GO Cellular Component (view graph)
ID Description Evidence Links
5839 proteasome core complex (sensu Eukaryota) inferred from electronic annotation QuickGO AmiGO
GO Molecular Function (view graph)
ID Description Evidence Links
4175 endopeptidase activity inferred from electronic annotation QuickGO AmiGO
Protein Similarities
Method ID Description E-Value
blast AAF60416 Proteasome alpha subunit protein 3 [Caenorhabditis elegans] ref|NP_491520.2| Y110A7A.14 [Caenorhabditis elegans] sp|Q9N599|PSA4_CAEEL Proteasome subunit alpha type 4 (Proteasome subunit alpha 3) 1.0E-132
blast CAE65730 Hypothetical protein CBG10813 [Caenorhabditis briggsae] 1.0E-128
Protein Domains
Database ID Description E-Value
Pfam IPR001353 EMBL-EBI Peptidase T1, 20S proteasome 7.6E-66
Sequence
Target Sequence 
>C. ELEGANS:192103_S_AT
ggtctaccgtctttcggacaacatctcgtgcactgtcgctggtatcaccgccgacgcgaa
catcctcatcaaccacttgagatggtgggctgccagctatcgtaacagttacggagagga
aatgccagttgagcagctcgtccagaatctttgcaatgaaaagcagagatacacgcagat
tggaggaaagagaccgttcggagtgtcacttctctatatcggatgggataagcactacgg
atatcaactttaccaatctgatccttccggaaactacactggatggaaggcaacctgcat
cggaagcaaccaccaggctgccgtaaccttgttgaaacaggagtacaaatccccaaatct
tgaagaagcaaagcagttggctatcaaggttctctggaagactttggatgtgaagctcgc
ttccgagaaagttgagatggctgttttgactcgtcgtgatggaaagactgtgctcgaaga
gctcaccaccaaggaagtcgatgctctgattgctga

BLASTn GenBank NR
Probe Info
Probe Sequence(5'-3') Probe X Probe Y Probe Interrogation
Position 		Strandedness
GGTCTACCGTCTTTCGGACAACATC 202 501 303 Antisense
GAGATGGTGGGCTGCCAGCTATCGT 588 395 381 Antisense
GAAATGCCAGTTGAGCAGCTCGTCC 291 361 421 Antisense
CAGCTCGTCCAGAATCTTTGCAATG 59 205 436 Antisense
AGAGACCGTTCGGAGTGTCACTTCT 616 67 491 Antisense
GTGTCACTTCTCTATATCGGATGGG 680 485 505 Antisense
TTTACCAATCTGATCCTTCCGGAAA 349 673 551 Antisense
CCAGGCTGCCGTAACCTTGTTGAAA 25 269 615 Antisense
GAGATGGCTGTTTTGACTCGTCGTG 45 397 736 Antisense
GACTGTGCTCGAAGAGCTCACCACC 684 375 768 Antisense
AGGAAGTCGATGCTCTGATTGCTGA 416 53 794 Antisense
Sequence Source Affymetrix Proprietary Database