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[192067_at] phosphatidylinositol 4-kinase

Description F35H12.4 /REP_DB=WormBase Gene ID /WP=CE04513 /TR=Q20077 /GB=AAK39229.1 /SUBMIT=ST.LOUIS /CHR=X /FEA=Sanger Annotation /DEF=phosphatidylinositol 4-kinase
Cluster 6grp_highest_10_10 > 49      6grp_high1_10_10 > 83      4grp_highest_8_8 > 05      4grp_high_8_8 > 30      6grp_highest_nonorm > 81      6grp_total > 74      4grp_total > 24      6grp_highest_sub > 04_05_06      6grp_high1_sub > 04      

Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 150
1 2 3 4 range
A 184.5
(-2.8)
P 		182.6
(-3)
P 		239
(3)
P 		210.1
(-0.1)
P 		56
B 180.9
(-2.7)
P 		220.5
(-1.1)
P 		172.8
(-3)
P 		322.9
(3)
P 		150
C 178
(-3)
P 		248
(1.7)
P 		266.8
(3)
P 		188.7
(-2.3)
P 		89
avr 181.1
(-3) 		217
(0.6) 		226.2
(1.5) 		240.6
(3) 		60

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 157
1 2 3 4 5 6 range
A 163.8
(-3)
P 		250.6
(0.3)
P 		276.7
(1.3)
P 		320.7
(3)
P 		232.7
(-0.4)
P 		244.6
(0.1)
P 		157
B 262.7
(-0.1)
P 		239.7
(-1.8)
P 		223.2
(-3)
P 		232.1
(-2.3)
P 		305.3
(3)
P 		285.1
(1.5)
P 		82
C 201.7
(-3)
P 		216.3
(-2.1)
P 		296.4
(2.6)
P 		261.8
(0.6)
P 		302.3
(3)
P 		273.5
(1.3)
P 		101
avr 209.4
(-3) 		235.5
(-0.8) 		265.4
(1.8) 		271.5
(2.3) 		280.1
(3) 		267.7
(1.9) 		71
No Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 62
1 2 3 4 range
A 67.2
(3)
P 		39.6
(-1.5)
P 		62.5
(2.2)
P 		30.8
(-3)
P 		36
B 57.7
(0.7)
P 		54.5
(0)
P 		40
(-3)
P 		68.8
(3)
P 		29
C 58.9
(-0.3)
P 		71.3
(0.9)
P 		93
(3)
P 		31.8
(-3)
P 		61
avr 61.3
(1.9) 		55.1
(0.2) 		65.2
(3) 		43.8
(-3) 		21

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 94
1 2 3 4 5 6 range
A 30.2
(-3)
P 		89.1
(3)
P 		60.3
(0.1)
P 		81.3
(2.2)
P 		70.2
(1.1)
P 		59.6
(-0)
P 		59
B 91.4
(0.2)
P 		79.8
(-0.8)
P 		54.2
(-3)
P 		61.5
(-2.4)
P 		124.1
(3)
P 		106.3
(1.5)
P 		70
C 74.8
(-0.1)
P 		66
(-1.2)
P 		75.4
(0)
P 		52.6
(-3)
P 		97.8
(3)
P 		91.6
(2.2)
P 		45
avr 65.5
(-2.6) 		78.3
(-0.4) 		63.3
(-3) 		65.1
(-2.7) 		97.4
(3) 		85.8
(1) 		34
NetAffx Links Cluster Members
Consensus/Exemplar
GeneChip Array Information
Probe Set ID 192067_at
GeneChip Array C. elegans Genome Array
Organism Common Name Nematode
Probe Design Information
Transcript ID(Array Design) affy.Ce.18466
Sequence Type Exemplar sequence
Representative Public ID F35H12.4 NCBI
Target Description F35H12.4 /REP_DB=WormBase Gene ID /WP=CE04513 /TR=Q20077 /GB=AAK39229.1 /SUBMIT=ST.LOUIS /CHR=X /FEA=Sanger Annotation /DEF=phosphatidylinositol 4-kinase
Cluster Evidence This cluster is supported by a Sanger Annotation.
Annotation Method Description
Annotation Description This probe set was annotated using the Matching Probes based pipeline to a RefSeq identifier using 1 transcript(s).
Annotation Grade This is a grade A annotation.
Annotation Transcript Cluster (# of Matching Probes) NM_075776(11)
Transcript Assignments
Representative
Transcript		 Description Matching Probes Related Probesets by Grade
NM_075776 NCBI Caenorhabditis elegans F35H12.4 (F35H12.4) mRNA, complete cds. 11/11 None
GENEFINDER00000028616 ENSEMBL cdna:GeneFinder chromosome:CEL140:X:920305:924507:-1 11/11 None
F35H12.4 ENSEMBL cdna:known chromosome:CEL140:X:920252:924436:-1 gene:F35H12.4 11/11 None
Annotation Notes
Cross Hybridizing mRNA Matched Probes Nature of Assignment Related Probesets by Grade
SNAP00000028609 8/11 Cross Hyb Matching Probes None
Genomic Alignment of Consensus/Exemplar Sequence
Assembly Wormbase March 2004
Alignment(s)
Position Identity Coverage Cytoband
chrX:920304-923893(-) 100.0 100.0
Public Domain and Genome References
Gene Title phosphatidylinositol 4-kinase
Ensembl F35H12.4
Entrez Gene 180443 Entrez gene
SwissProt Q20077 EMBL-EBI
WormBase CE04513 Wormbase
Functional Annotations
Ortholog
ID Title Organism
CANINE_2:CFA.16299.1.S1_AT similar to phosphatidylinositol 4-kinase, catalytic, beta polypeptide cfa
CANINE_2:CFAAFFX.19593.1.S1_S_AT similar to phosphatidylinositol 4-kinase, catalytic, beta polypeptide cfa
DROSOPHILA_2:1634509_S_AT four wheel drive dm
DROSGENOME1:141383_AT four wheel drive dm
CHICKEN:GGAAFFX.551.1.S1_S_AT similar to PIK4CB protein gga
HG-U133_PLUS_2:206139_AT phosphatidylinositol 4-kinase, catalytic, beta polypeptide hs
HG-U133A:206139_AT phosphatidylinositol 4-kinase, catalytic, beta polypeptide hs
HG-FOCUS:206139_AT phosphatidylinositol 4-kinase, catalytic, beta polypeptide hs
HG-U133A_2:206139_AT phosphatidylinositol 4-kinase, catalytic, beta polypeptide hs
HG-U133_PLUS_2:206138_S_AT phosphatidylinositol 4-kinase, catalytic, beta polypeptide hs
HG-U133A:206138_S_AT phosphatidylinositol 4-kinase, catalytic, beta polypeptide hs
HG-U133A_2:206138_S_AT phosphatidylinositol 4-kinase, catalytic, beta polypeptide hs
HG-U95AV2:146_AT phosphatidylinositol 4-kinase, catalytic, beta polypeptide hs
HC-G110:146_AT phosphatidylinositol 4-kinase, catalytic, beta polypeptide hs
HG-U133_PLUS_2:210417_S_AT phosphatidylinositol 4-kinase, catalytic, beta polypeptide hs
HG-U133A:210417_S_AT phosphatidylinositol 4-kinase, catalytic, beta polypeptide hs
HG-U133A_2:210417_S_AT phosphatidylinositol 4-kinase, catalytic, beta polypeptide hs
HU35KSUBA:HUM_ALU_AT phosphatidylinositol 4-kinase, catalytic, beta polypeptide hs
HU35KSUBB:HUM_ALU_AT phosphatidylinositol 4-kinase, catalytic, beta polypeptide hs
HU35KSUBC:HUM_ALU_AT phosphatidylinositol 4-kinase, catalytic, beta polypeptide hs
HU35KSUBD:HUM_ALU_AT phosphatidylinositol 4-kinase, catalytic, beta polypeptide hs
HUGENEFL:HUM_ALU_AT phosphatidylinositol 4-kinase, catalytic, beta polypeptide hs
HC-G110:HUM_ALU_AT phosphatidylinositol 4-kinase, catalytic, beta polypeptide hs
HUGENEFL:U81802_AT phosphatidylinositol 4-kinase, catalytic, beta polypeptide hs
U133_X3P:G4505808_3P_AT phosphatidylinositol 4-kinase, catalytic, beta polypeptide hs
U133_X3P:G4505808_3P_A_AT phosphatidylinositol 4-kinase, catalytic, beta polypeptide hs
U133_X3P:G1894946_3P_A_AT phosphatidylinositol 4-kinase, catalytic, beta polypeptide hs
HG-U95AV2:40253_AT phosphatidylinositol 4-kinase, catalytic, beta polypeptide hs
HG-U95E:71609_AT phosphatidylinositol 4-kinase, catalytic, beta polypeptide hs
HU35KSUBA:AA227592_AT Phosphatidylinositol 4-kinase, catalytic, beta polypeptide hs
MU11KSUBB:MSA.32602.0_S_AT phosphatidylinositol 4-kinase, catalytic, beta polypeptide mm
MOE430B:1439197_AT phosphatidylinositol 4-kinase, catalytic, beta polypeptide mm
MOUSE430_2:1439197_AT phosphatidylinositol 4-kinase, catalytic, beta polypeptide mm
MU19KSUBC:TC37928_AT Phosphatidylinositol 4-kinase, catalytic, beta polypeptide, mRNA (cDNA clone MGC:100291 IMAGE:5707855) mm
RG-U34A:D84667_AT phosphatidylinositol 4-kinase, catalytic, beta polypeptide rn
RT-U34:D84667_AT phosphatidylinositol 4-kinase, catalytic, beta polypeptide rn
RT-U34:D84667_G_AT phosphatidylinositol 4-kinase, catalytic, beta polypeptide rn
RG-U34A:D84667_G_AT phosphatidylinositol 4-kinase, catalytic, beta polypeptide rn
RG-U34A:RC_AI102103_AT phosphatidylinositol 4-kinase, catalytic, beta polypeptide rn
RG-U34A:RC_AI102103_G_AT phosphatidylinositol 4-kinase, catalytic, beta polypeptide rn
RG-U34B:RC_AI029581_AT phosphatidylinositol 4-kinase, catalytic, beta polypeptide rn
RG-U34C:R46930_S_AT phosphatidylinositol 4-kinase, catalytic, beta polypeptide rn
RAE230A:1374689_AT phosphatidylinositol 4-kinase, catalytic, beta polypeptide rn
RAT230_2:1374689_AT phosphatidylinositol 4-kinase, catalytic, beta polypeptide rn
RAE230A:1369039_AT phosphatidylinositol 4-kinase, catalytic, beta polypeptide rn
RAT230_2:1369039_AT phosphatidylinositol 4-kinase, catalytic, beta polypeptide rn
RAE230B:1382414_AT Phosphatidylinositol 4-kinase, catalytic, beta polypeptide rn
RAT230_2:1382414_AT Phosphatidylinositol 4-kinase, catalytic, beta polypeptide rn
RAE230B:1384062_AT Phosphatidylinositol 4-kinase, catalytic, beta polypeptide rn
RAT230_2:1384062_AT Phosphatidylinositol 4-kinase, catalytic, beta polypeptide rn
RG-U34B:RC_AI043787_AT Phosphatidylinositol 4-kinase, catalytic, beta polypeptide rn
RG-U34C:RC_AI072443_AT Phosphatidylinositol 4-kinase, catalytic, beta polypeptide rn
RG-U34C:RC_AI172576_AT Phosphatidylinositol 4-kinase, catalytic, beta polypeptide rn
Gene Ontology
GO Molecular Function (view graph)
ID Description Evidence Links
16773 phosphotransferase activity, alcohol group as acceptor inferred from electronic annotation QuickGO AmiGO
Protein Similarities
Method ID Description E-Value
blast AAK39229 Hypothetical protein F35H12.4 [Caenorhabditis elegans] ref|NP_508177.1| F35H12.4 [Caenorhabditis elegans] 0.0
blast CAE63599 Hypothetical protein CBG08090 [Caenorhabditis briggsae] 0.0
blast XP_691728 PREDICTED: similar to phosphatidylinositol 4-kinase b [Danio rerio] 1.0E-120
blast XP_691728 PREDICTED: similar to phosphatidylinositol 4-kinase b [Danio rerio] 1.0E-117
Protein Domains
Database ID Description E-Value
Pfam IPR000403 EMBL-EBI Phosphatidylinositol 3- and 4-kinase 4.3E-36
Pfam IPR000403 EMBL-EBI Phosphatidylinositol 3- and 4-kinase 4.3E-36
Sequence
Target Sequence 
>C. ELEGANS:192067_AT
gacaccatcgctgaaacatcactttgaaaatgtatttggacctgtgaatagtgaaactta
tgtgaatgctcagaaaaacttcattcaaagcacagcggcctatagccttgtcagttatta
tctgcaattgaaagaccgccacaatggaaacattttattggatatggacggtcacttgat
ccatattgattatggttttttgctttcctcgtctcctagaaatttgggttttgaaacagc
gccatttaaattgacaactgaaattattgatgtgatgggtgggatcgacagcgacatgtt
tctgtatttcaaaagtttgctactccgtggattaatggcagcgagaaaacaccaccgacg
gattgtatcgctcgctgaaattatgtctgcaggatcaaaaatgcaatgcttccgtgctgg
cgcagagactgttcgagctctagaagctagattccatgtaagcagcactgacgagcagct
ccaacaactcgtcgacacgcttgtag

BLASTn GenBank NR
Probe Info
Probe Sequence(5'-3') Probe X Probe Y Probe Interrogation
Position 		Strandedness
GACACCATCGCTGAAACATCACTTT 676 367 1251 Antisense
CACAGCGGCCTATAGCCTTGTCAGT 539 195 1341 Antisense
GGACGGTCACTTGATCCATATTGAT 555 523 1416 Antisense
GATTATGGTTTTTTGCTTTCCTCGT 63 431 1438 Antisense
GTGGGATCGACAGCGACATGTTTCT 387 487 1529 Antisense
ACACCACCGACGGATTGTATCGCTC 46 107 1599 Antisense
GTATCGCTCGCTGAAATTATGTCTG 358 455 1615 Antisense
AAAAATGCAATGCTTCCGTGCTGGC 217 129 1647 Antisense
GTGCTGGCGCAGAGACTGTTCGAGC 18 477 1664 Antisense
TAAGCAGCACTGACGAGCAGCTCCA 708 635 1709 Antisense
CAACAACTCGTCGACACGCTTGTAG 706 189 1732 Antisense
Sequence Source Affymetrix Proprietary Database