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[192065_at] G-protein coupled receptor

Description C52B11.3 /REP_DB=WormBase Gene ID /WP=CE04259 /TR=SW:Q18775 /GB=AAA82470.1 /SUBMIT=ST.LOUIS /CHR=X /FEA=Sanger Annotation /DEF=G-protein coupled receptor
Cluster 6grp_high1_10_10 > 29      4grp_high_8_8 > 03      6grp_total > 38      4grp_total > 13      6grp_high1_sub > Cu      6grp_total_sub > Cup      

Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 126
1 2 3 4 range
A 149.4
(0.7)
P 		91
(-3)
P 		126.8
(-0.7)
P 		185.7
(3)
P 		95
B 110.3
(0.6)
P 		72.4
(-2.1)
A 		60.1
(-3)
P 		144.8
(3)
P 		85
C 106.3
(-0.5)
P 		82.5
(-1.9)
A 		64.4
(-3)
P 		164
(3)
P 		100
avr 122
(-0.1) 		82
(-3) 		83.8
(-2.9) 		164.8
(3) 		83

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 123
1 2 3 4 5 6 range
A 165.4
(3)
P 		97.2
(-1.5)
P 		74.3
(-3)
P 		83
(-2.4)
M 		115.8
(-0.3)
P 		120.2
(0)
P 		91
B 133.4
(2.1)
P 		145.8
(3)
P 		59.5
(-3)
P 		65.6
(-2.6)
P 		79.7
(-1.6)
P 		94.7
(-0.6)
P 		86
C 112
(2.6)
P 		116.4
(3)
P 		42.6
(-3)
A 		111.3
(2.6)
P 		78.5
(-0.1)
P 		107.2
(2.3)
P 		74
avr 136.9
(3) 		119.8
(1.7) 		58.8
(-3) 		86.6
(-0.9) 		91.3
(-0.5) 		107.4
(0.7) 		78
No Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 41
1 2 3 4 range
A 54.4
(3)
P 		19.7
(-3)
P 		33.1
(-0.7)
P 		27.2
(-1.7)
P 		35
B 35.2
(3)
P 		17.9
(-1.9)
A 		13.9
(-3)
P 		30.9
(1.8)
P 		21
C 35.2
(3)
P 		23.7
(-2.4)
A 		22.5
(-3)
P 		27.7
(-0.5)
P 		13
avr 41.6
(3) 		20.4
(-3) 		23.2
(-2.2) 		28.6
(-0.7) 		21

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 38
1 2 3 4 5 6 range
A 30.5
(1.6)
P 		34.6
(2.9)
P 		16.2
(-3)
P 		21.1
(-1.4)
M 		34.9
(3)
P 		29.3
(1.2)
P 		19
B 46.4
(2.6)
P 		48.5
(3)
P 		14.5
(-3)
P 		17.4
(-2.5)
P 		32.4
(0.2)
P 		35.3
(0.7)
P 		34
C 41.5
(3)
P 		35.5
(1.8)
P 		10.8
(-3)
A 		22.4
(-0.7)
P 		25.4
(-0.1)
P 		35.9
(1.9)
P 		31
avr 39.5
(3) 		39.5
(3) 		13.8
(-3) 		20.3
(-1.5) 		30.9
(1) 		33.5
(1.6) 		26
NetAffx Links Cluster Members
Consensus/Exemplar
GeneChip Array Information
Probe Set ID 192065_at
GeneChip Array C. elegans Genome Array
Organism Common Name Nematode
Probe Design Information
Transcript ID(Array Design) affy.Ce.18576
Sequence Type Exemplar sequence
Representative Public ID C52B11.3 NCBI
Target Description C52B11.3 /REP_DB=WormBase Gene ID /WP=CE04259 /TR=SW:Q18775 /GB=AAA82470.1 /SUBMIT=ST.LOUIS /CHR=X /FEA=Sanger Annotation /DEF=G-protein coupled receptor
Cluster Evidence This cluster is supported by a Sanger Annotation.
Annotation Method Description
Annotation Description This probe set was annotated using the Matching Probes based pipeline to a RefSeq identifier using 1 transcript(s).
Annotation Grade This is a grade A annotation.
Annotation Transcript Cluster (# of Matching Probes) NM_075837(11)
Transcript Assignments
Representative
Transcript		 Description Matching Probes Related Probesets by Grade
NM_075837 NCBI Caenorhabditis elegans C52B11.3 (C52B11.3) mRNA, complete cds. 11/11 None
GENEFINDER00000006105 ENSEMBL cdna:GeneFinder chromosome:CEL140:X:1294888:1309365:1 9/11 None
C52B11.3 ENSEMBL cdna:known chromosome:CEL140:X:1294888:1300402:1 gene:C52B11.3 11/11 None
Annotation Notes
Cross Hybridizing mRNA Matched Probes Nature of Assignment Related Probesets by Grade
SNAP00000006101 8/11 Cross Hyb Matching Probes None
Genomic Alignment of Consensus/Exemplar Sequence
Assembly Wormbase March 2004
Alignment(s)
Position Identity Coverage Cytoband
chrX:1294887-1300402(+) 96.92 100.0
Public Domain and Genome References
Gene Title G-protein coupled receptor
Ensembl C52B11.3
Entrez Gene 183715 Entrez gene
SwissProt Q18775 EMBL-EBI
WormBase CE04259 Wormbase
Functional Annotations
Gene Ontology
GO Biological Process (view graph)
ID Description Evidence Links
7186 G-protein coupled receptor protein signaling pathway inferred from electronic annotation QuickGO AmiGO
GO Cellular Component (view graph)
ID Description Evidence Links
16021 integral to membrane inferred from electronic annotation QuickGO AmiGO
GO Molecular Function (view graph)
ID Description Evidence Links
1584 rhodopsin-like receptor activity inferred from electronic annotation QuickGO AmiGO
Protein Similarities
Method ID Description E-Value
blast NP_508238 C52B11.3 [Caenorhabditis elegans] sp|Q18775|YYI3_CAEEL Probable G-protein coupled receptor C52B11.3 0.0
blast AAA82470 Hypothetical protein C52B11.3 [Caenorhabditis elegans] 0.0
blast CAE63568 Hypothetical protein CBG08056 [Caenorhabditis briggsae] 0.0
Protein Domains
Database ID Description E-Value
Pfam IPR000276 EMBL-EBI Rhodopsin-like GPCR superfamily 2.3E-84
Pfam IPR003131 EMBL-EBI K+ channel tetramerisation 1.4E-35
Pfam IPR000276 EMBL-EBI Rhodopsin-like GPCR superfamily 2.0E-96
Trans Membrane
ID Number Of Domains Domain Boundaries
NP_508238.1 8 115-137,200-222,242-264,285-307,335-357,532-554,569-591,666-688
C52B11.3 8 115-137,200-222,242-264,285-307,335-357,532-554,569-591,666-688
GENEFINDER00000006105 6 115-137,150-172,187-209,230-252,280-302,476-498
Sequence
Target Sequence 
>C. ELEGANS:192065_AT
tgatcagccggatcgtatgtcgctctcctccaactcccaaatggtgatgacatctccctt
atcaacgcgtcgaaaattgaatgttcgagaaaaatcgcgccaaatgatgcgctacgtcca
cgagcaacgtgcagctcggacactttccattgtggtcggagcatttattctctgctggac
accatttttcgtgttcactccgctcaccgcgttctgtgaaagttgtttctccaacaaaga
gaccatcttcacattcgtcacatgggccggtcacctaaactcaatgctcaacccgctcat
ctactcgcgcttctcgcgagatttcagacgggcattcaagcaaattctcacgtgtcaacg
ccagcaaaaggtgaaaaccgcatttaaaacgccactgtcactcgtgttcactcaactcat
ctcggtcacccaaatggcaccgagattttcttcattagctgagatttcctttcgtcggc

BLASTn GenBank NR
Probe Info
Probe Sequence(5'-3') Probe X Probe Y Probe Interrogation
Position 		Strandedness
TGATCAGCCGGATCGTATGTCGCTC 481 565 1473 Antisense
GCTACGTCCACGAGCAACGTGCAGC 72 303 1583 Antisense
CAGCTCGGACACTTTCCATTGTGGT 29 205 1604 Antisense
ATTTATTCTCTGCTGGACACCATTT 668 13 1635 Antisense
AAGAGACCATCTTCACATTCGTCAC 252 155 1709 Antisense
GTCACCTAAACTCAATGCTCAACCC 420 461 1742 Antisense
GCTTCTCGCGAGATTTCAGACGGGC 93 307 1781 Antisense
AAGCAAATTCTCACGTGTCAACGCC 242 151 1810 Antisense
TTAAAACGCCACTGTCACTCGTGTT 91 681 1856 Antisense
GGCACCGAGATTTTCTTCATTAGCT 81 537 1908 Antisense
TTAGCTGAGATTTCCTTTCGTCGGC 309 681 1927 Antisense
Sequence Source Affymetrix Proprietary Database