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[192057_at] Mitochondrial carrier family

Description K11H3.3 /REP_DB=WormBase Gene ID /WP=CE00474 /TR=SW:P34519 /GB=CAA80178.1 /SUBMIT=HINXTON /CHR=3 /FEA=Sanger Annotation /DEF=Mitochondrial carrier family
Cluster 6grp_highest_10_10 > 23      6grp_high1_10_10 > 02      4grp_highest_8_8 > 34      4grp_high_8_8 > 57      6grp_highest_nonorm > 70      6grp_total > 34      4grp_total > 62      6grp_highest_sub > 01_02_03      6grp_high1_sub > De      6grp_total_sub > Decrease      

Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 183
1 2 3 4 range
A 377.3
(3)
P 		223.2
(-2.8)
P 		327
(1.1)
P 		216.7
(-3)
P 		161
B 363.6
(3)
P 		266.2
(-1.3)
P 		300.3
(0.2)
P 		226.4
(-3)
P 		137
C 379.2
(3)
P 		306.5
(0.6)
P 		327.9
(1.3)
P 		196.7
(-3)
P 		183
avr 373.4
(3) 		265.3
(-1.1) 		318.4
(0.9) 		213.3
(-3) 		160

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 278
1 2 3 4 5 6 range
A 378.1
(1.9)
P 		359.2
(1.5)
P 		428.8
(3)
P 		239.1
(-1.2)
P 		158.3
(-3)
P 		236.6
(-1.3)
P 		271
B 436
(3)
P 		360.9
(1.3)
P 		396.2
(2.1)
P 		265.7
(-0.9)
P 		176.3
(-3)
P 		244.2
(-1.4)
P 		260
C 355.9
(2.3)
P 		379.5
(3)
P 		376.2
(2.9)
P 		247.2
(-1.2)
P 		189.8
(-3)
P 		192
(-2.9)
P 		190
avr 390
(2.7) 		366.5
(2.1) 		400.4
(3) 		250.7
(-1) 		174.8
(-3) 		224.3
(-1.7) 		226
No Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 106
1 2 3 4 range
A 137.4
(3)
P 		48.5
(-2)
P 		85.5
(0.1)
P 		31.7
(-3)
P 		106
B 116
(3)
P 		65.8
(-1.4)
P 		69.6
(-1.1)
P 		48.2
(-3)
P 		68
C 125.5
(3)
P 		88.1
(0.6)
P 		114.3
(2.3)
P 		33.2
(-3)
P 		92
avr 126.3
(3) 		67.5
(-1) 		89.8
(0.5) 		37.7
(-3) 		89

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 104
1 2 3 4 5 6 range
A 69.7
(-1.4)
P 		127.8
(3)
P 		93.4
(0.4)
P 		60.6
(-2)
P 		47.8
(-3)
P 		57.6
(-2.3)
P 		80
B 151.7
(3)
P 		120.1
(0.7)
P 		96.2
(-1.1)
P 		70.4
(-3)
P 		71.6
(-2.9)
P 		91
(-1.5)
P 		81
C 131.9
(3)
P 		115.8
(1.8)
P 		95.7
(0.4)
P 		49.7
(-3)
P 		61.4
(-2.1)
P 		64.3
(-1.9)
P 		82
avr 117.8
(2.7) 		121.2
(3) 		95.1
(0.4) 		60.2
(-3) 		60.3
(-3) 		71
(-1.9) 		61
NetAffx Links Cluster Members
Consensus/Exemplar
GeneChip Array Information
Probe Set ID 192057_at
GeneChip Array C. elegans Genome Array
Organism Common Name Nematode
Probe Design Information
Transcript ID(Array Design) affy.Ce.5999
Sequence Type Exemplar sequence
Representative Public ID K11H3.3 NCBI
Target Description K11H3.3 /REP_DB=WormBase Gene ID /WP=CE00474 /TR=SW:P34519 /GB=CAA80178.1 /SUBMIT=HINXTON /CHR=3 /FEA=Sanger Annotation /DEF=Mitochondrial carrier family
Cluster Evidence This cluster is supported by a Sanger Annotation.
Annotation Method Description
Annotation Description This probe set was annotated using the Matching Probes based pipeline to a RefSeq identifier using 1 transcript(s).
Annotation Grade This is a grade A annotation.
Annotation Transcript Cluster (# of Matching Probes) NM_066786(11)
Transcript Assignments
Representative
Transcript		 Description Matching Probes Related Probesets by Grade
NM_066786 NCBI Caenorhabditis elegans K11H3.3 (K11H3.3) mRNA, complete cds. 11/11 None
SNAP00000008461 ENSEMBL cdna:SNAP chromosome:CEL140:III:9851781:9853160:1 11/11 None
GENEFINDER00000008473 ENSEMBL cdna:GeneFinder chromosome:CEL140:III:9851781:9853160:1 11/11 None
K11H3.3 ENSEMBL cdna:known chromosome:CEL140:III:9851748:9853716:1 gene:K11H3.3 11/11 None
Annotation Notes
Cross Hybridizing mRNA Matched Probes Nature of Assignment Related Probesets by Grade
NM_065848 2/11 Cross Hyb Matching Probes None
GENEFINDER00000019671 2/11 Cross Hyb Matching Probes None
SNAP00000019669 2/11 Cross Hyb Matching Probes None
Y37B11A.3 2/11 Cross Hyb Matching Probes None
Genomic Alignment of Consensus/Exemplar Sequence
Assembly Wormbase March 2004
Alignment(s)
Position Identity Coverage Cytoband
chrIII:9851776-9853156(+) 100.0 100.0
Public Domain and Genome References
Gene Title Mitochondrial carrier family
Ensembl K11H3.3
Entrez Gene 176398 Entrez gene
SwissProt P34519 EMBL-EBI
WormBase CE00474 Wormbase
Functional Annotations
Ortholog
ID Title Organism
CANINE_2:CFA.20154.1.S1_AT similar to Tricarboxylate transport protein, mitochondrial precursor (Citrate transport protein) (CTP) (Tricarboxylate carrier protein) cfa
CANINE_2:CFAAFFX.22616.1.S1_S_AT similar to Tricarboxylate transport protein, mitochondrial precursor (Citrate transport protein) (CTP) (Tricarboxylate carrier protein) cfa
CHICKEN:GGA.5522.1.S1_AT similar to Hypothetical protein MGC76218 gga
CHICKEN:GGA.5522.2.S1_A_AT similar to Hypothetical protein MGC76218 gga
HG-U133_PLUS_2:210010_S_AT solute carrier family 25 (mitochondrial carrier; citrate transporter), member 1 hs
HG-U133A:210010_S_AT solute carrier family 25 (mitochondrial carrier; citrate transporter), member 1 hs
HG-U133A_2:210010_S_AT solute carrier family 25 (mitochondrial carrier; citrate transporter), member 1 hs
HU35KSUBC:RC_AA147471_F_AT solute carrier family 25 (mitochondrial carrier; citrate transporter), member 1 hs
HU35KSUBC:RC_AA079758_F_AT solute carrier family 25 (mitochondrial carrier; citrate transporter), member 1 hs
HU35KSUBD:RC_AA435777_F_AT solute carrier family 25 (mitochondrial carrier; citrate transporter), member 1 hs
HU35KSUBD:RC_W86850_F_AT solute carrier family 25 (mitochondrial carrier; citrate transporter), member 1 hs
HUGENEFL:X96924_RNA1_AT solute carrier family 25 (mitochondrial carrier; citrate transporter), member 1 hs
HUGENEFL:L77567_S_AT solute carrier family 25 (mitochondrial carrier; citrate transporter), member 1 hs
U133_X3P:G950003_3P_S_AT solute carrier family 25 (mitochondrial carrier; citrate transporter), member 1 hs
HG-U95AV2:38997_AT solute carrier family 25 (mitochondrial carrier; citrate transporter), member 1 hs
HG-U95AV2:38998_G_AT solute carrier family 25 (mitochondrial carrier; citrate transporter), member 1 hs
HG-U95AV2:39825_AT solute carrier family 25 (mitochondrial carrier; citrate transporter), member 1 hs
HG-U95C:64493_AT solute carrier family 25 (mitochondrial carrier; citrate transporter), member 1 hs
MU11KSUBA:C77781_RC_AT solute carrier family 25 (mitochondrial carrier, citrate transporter), member 1 mm
MU11KSUBB:MSA.14686.0_S_AT solute carrier family 25 (mitochondrial carrier, citrate transporter), member 1 mm
MU11KSUBB:MSA.21393.0_S_AT solute carrier family 25 (mitochondrial carrier, citrate transporter), member 1 mm
MU11KSUBB:MSA.19850.0_F_AT solute carrier family 25 (mitochondrial carrier, citrate transporter), member 1 mm
MG-U74AV2:94807_AT solute carrier family 25 (mitochondrial carrier, citrate transporter), member 1 mm
MG-U74AV2:162358_I_AT solute carrier family 25 (mitochondrial carrier, citrate transporter), member 1 mm
MOE430B:1428190_AT solute carrier family 25 (mitochondrial carrier, citrate transporter), member 1 mm
MOUSE430_2:1428190_AT solute carrier family 25 (mitochondrial carrier, citrate transporter), member 1 mm
MU19KSUBB:TC26681_AT Solute carrier family 25 (mitochondrial carrier, citrate transporter), member 1 (Slc25a1), mRNA mm
RG-U34A:L12016_AT solute carrier family 25, member 1 rn
RG-U34B:RC_AA996851_F_AT solute carrier family 25, member 1 rn
RG-U34B:RC_AA996852_F_AT solute carrier family 25, member 1 rn
RAE230A:1367773_AT solute carrier family 25, member 1 rn
RAT230_2:1367773_AT solute carrier family 25, member 1 rn
Gene Ontology
GO Biological Process (view graph)
ID Description Evidence Links
6810 transport inferred from electronic annotation QuickGO AmiGO
GO Cellular Component (view graph)
ID Description Evidence Links
16020 membrane inferred from electronic annotation QuickGO AmiGO
GO Molecular Function (view graph)
ID Description Evidence Links
5488 binding inferred from electronic annotation QuickGO AmiGO
Protein Similarities
Method ID Description E-Value
blast S40756 hypothetical protein K11H3.3 - Caenorhabditis elegans 0.0
blast CAA80178 Hypothetical protein K11H3.3 [Caenorhabditis elegans] ref|NP_499187.1| K11H3.3 [Caenorhabditis elegans] sp|P34519|TXTP_CAEEL Putative tricarboxylate transport protein, mitochondrial precursor (Citrate transport protein) (CTP) 1.0E-170
blast CAE65099 Hypothetical protein CBG09959 [Caenorhabditis briggsae] 1.0E-165
blast S40756 hypothetical protein K11H3.3 - Caenorhabditis elegans 1.0E-156
Protein Domains
Database ID Description E-Value
Pfam IPR001993 EMBL-EBI Mitochondrial substrate carrier 1.4E-25
Pfam IPR001993 EMBL-EBI Mitochondrial substrate carrier 8.7E-29
Pfam IPR001993 EMBL-EBI Mitochondrial substrate carrier 4.2E-27
Pfam IPR001993 EMBL-EBI Mitochondrial substrate carrier 8.4E-23
Pfam IPR001993 EMBL-EBI Mitochondrial substrate carrier 8.7E-29
Pfam IPR001993 EMBL-EBI Mitochondrial substrate carrier 4.2E-27
Sequence
Target Sequence 
>C. ELEGANS:192057_AT
gaaatctatctccagtaatgcgacttctttgtggattgggagctggtctctctgaagccg
tatttgcagtaacacctatggaaactgtaaaagtgaaatttattcatgatcaaggacttg
ctcaaccaaaatacaaaggatttgtgcatggagttggatgtattgtaaaagcagaaggac
ttggtggtatatataaaggagttactgcaacaatggccaaacaaggatccaatcaagcga
ttcgattctttgtaatggaaactctcaaagattggtatcgtggtggtgacaatactcaac
cgatctcaaaaccaatcgtcggacttatgggagcagttgctggagctgcttctgtttatg
gaaatactccgattgatgtagtgaaaactcgtatgcaaggtctcgaagcgaaaaagtaca
agaatactttggattgtgcaatgcaaatttggaagaaagaaggattcttcgccttctaca
agggaacagtacctcgtctttctcgagtctgcctcgacgtcggaatcactttcatg

BLASTn GenBank NR
Probe Info
Probe Sequence(5'-3') Probe X Probe Y Probe Interrogation
Position 		Strandedness
GAAATCTATCTCCAGTAATGCGACT 591 361 362 Antisense
AATGCGACTTCTTTGTGGATTGGGA 326 167 378 Antisense
GATTGGGAGCTGGTCTCTCTGAAGC 593 435 395 Antisense
GAAGCCGTATTTGCAGTAACACCTA 93 345 415 Antisense
GGAGTTACTGCAACAATGGCCAAAC 244 517 559 Antisense
GGTGACAATACTCAACCGATCTCAA 402 499 646 Antisense
GATCTCAAAACCAATCGTCGGACTT 659 413 663 Antisense
GTTGCTGGAGCTGCTTCTGTTTATG 111 441 697 Antisense
GGATTCTTCGCCTTCTACAAGGGAA 55 509 823 Antisense
CAAGGGAACAGTACCTCGTCTTTCT 526 183 840 Antisense
CCTCGACGTCGGAATCACTTTCATG 706 265 873 Antisense
Sequence Source Affymetrix Proprietary Database