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[192049_at] NADH-ubiquinone oxidoreductase

Description C09H10.3 /REP_DB=WormBase Gene ID /WP=CE02132 /TR=Q17880 /GB=CAA90435.1 /SUBMIT=HINXTON /CHR=2 /FEA=Sanger Annotation /DEF=NADH-ubiquinone oxidoreductase
Cluster 6grp_highest_10_10 > 05      6grp_high1_10_10 > 10      4grp_highest_8_8 > 01      4grp_high_8_8 > 54      6grp_highest_nonorm > 46      6grp_total > 41      4grp_total > 58      6grp_highest_sub > 03_04      6grp_cgc > 60      6grp_total_sub > Hat      

Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 1698
1 2 3 4 range
A 3058.7
(-2)
P 		4233.5
(3)
P 		3782.9
(1.1)
P 		2830.1
(-3)
P 		1403
B 3103.5
(-2.1)
P 		3561.3
(-0.5)
P 		4528.2
(3)
P 		2854.2
(-3)
P 		1674
C 3381.1
(-1)
P 		3805.8
(3)
P 		3176.2
(-3)
P 		3199.7
(-2.8)
P 		630
avr 3181.1
(-1.5) 		3866.9
(3) 		3829.1
(2.7) 		2961.3
(-3) 		906

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 2676
1 2 3 4 5 6 range
A 3176.6
(0.2)
P 		3959.2
(3)
P 		3538
(1.5)
P 		3729.9
(2.2)
P 		2280.8
(-3)
P 		2823.7
(-1.1)
P 		1678
B 2425.1
(-0.8)
P 		2464.7
(-0.6)
P 		2483
(-0.5)
P 		3157
(3)
P 		2630.7
(0.3)
P 		2002.1
(-3)
P 		1155
C 4289
(2.5)
P 		2614.8
(-1.3)
P 		4520
(3)
P 		3158.9
(-0.1)
P 		2973.8
(-0.5)
P 		1844.3
(-3)
P 		2676
avr 3296.9
(2) 		3012.9
(0.7) 		3513.7
(3) 		3348.6
(2.2) 		2628.4
(-1.1) 		2223.4
(-3) 		1290
No Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 705
1 2 3 4 range
A 1113.7
(3)
P 		919
(1.3)
P 		988.9
(1.9)
P 		414.3
(-3)
P 		699
B 989.7
(2.2)
P 		879.6
(0.7)
P 		1049.3
(3)
P 		608.2
(-3)
P 		441
C 1119.2
(3)
P 		1094.2
(2.7)
P 		1107
(2.9)
P 		539.5
(-3)
P 		580
avr 1074.2
(3) 		964.3
(1.8) 		1048.4
(2.7) 		520.7
(-3) 		554

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 1004
1 2 3 4 5 6 range
A 585.6
(-3)
P 		1408.1
(3)
P 		770.5
(-1.7)
P 		946
(-0.4)
P 		688.3
(-2.3)
P 		687.5
(-2.3)
P 		823
B 843.8
(0.1)
P 		820.4
(-0.2)
P 		602.9
(-3)
P 		836.2
(0)
P 		1068.8
(3)
P 		746.6
(-1.1)
P 		466
C 1589.7
(3)
P 		797.8
(-1.9)
P 		1150.4
(0.3)
P 		635.3
(-2.9)
P 		962.3
(-0.9)
P 		617.4
(-3)
P 		972
avr 1006.4
(3) 		1008.8
(3) 		841.3
(-0.1) 		805.8
(-0.7) 		906.5
(1.1) 		683.8
(-3) 		325
NetAffx Links Cluster Members
Consensus/Exemplar
GeneChip Array Information
Probe Set ID 192049_at
GeneChip Array C. elegans Genome Array
Organism Common Name Nematode
Probe Design Information
Transcript ID(Array Design) affy.Ce.3482
Sequence Type Exemplar sequence
Representative Public ID C09H10.3 NCBI
Target Description C09H10.3 /REP_DB=WormBase Gene ID /WP=CE02132 /TR=Q17880 /GB=CAA90435.1 /SUBMIT=HINXTON /CHR=2 /FEA=Sanger Annotation /DEF=NADH-ubiquinone oxidoreductase
Cluster Evidence This cluster is supported by a Sanger Annotation.
Annotation Method Description
Annotation Description This probe set was annotated using the Matching Probes based pipeline to a RefSeq identifier using 1 transcript(s).
Annotation Grade This is a grade A annotation.
Annotation Transcript Cluster (# of Matching Probes) NM_063975(11)
Transcript Assignments
Representative
Transcript		 Description Matching Probes Related Probesets by Grade
NM_063975 NCBI Caenorhabditis elegans NADH Ubiquinone Oxidoreductase family member (nuo-1) (nuo-1) mRNA, complete cds. 11/11 None
SNAP00000010330 ENSEMBL cdna:SNAP chromosome:CEL140:II:11097758:11100375:1 9/11 None
GENEFINDER00000010342 ENSEMBL cdna:GeneFinder chromosome:CEL140:II:11097758:11099902:1 11/11 None
C09H10.3 ENSEMBL cdna:known chromosome:CEL140:II:11097758:11100231:1 gene:C09H10.3 11/11 None
Annotation Notes
Cross Hybridizing mRNA Matched Probes Nature of Assignment Related Probesets by Grade
Genomic Alignment of Consensus/Exemplar Sequence
Assembly Wormbase March 2004
Alignment(s)
Position Identity Coverage Cytoband
chrII:11097754-11099899(+) 100.0 100.0
Public Domain and Genome References
Gene Title NADH-ubiquinone oxidoreductase
Gene Symbol nuo-1
Ensembl C09H10.3
Entrez Gene 174696 Entrez gene
SwissProt Q17880 EMBL-EBI
WormBase CE02132 Wormbase
Functional Annotations
Ortholog
ID Title Organism
ATH1-121501:250534_AT NADH-ubiquinone oxidoreductase 51 kDa subunit, mitochondrial, putative at
CANINE:1583119_AT similar to NADH dehydrogenase (ubiquinone) flavoprotein 1, 51kDa cfa
CANINE:1603659_AT similar to NADH dehydrogenase (ubiquinone) flavoprotein 1, 51kDa cfa
CANINE_2:CFAAFFX.17348.1.S1_AT similar to NADH dehydrogenase (ubiquinone) flavoprotein 1, 51kDa cfa
CANINE_2:CFAAFFX.17348.1.S1_S_AT similar to NADH dehydrogenase (ubiquinone) flavoprotein 1, 51kDa cfa
DROSOPHILA_2:1633269_AT dm
DROSGENOME1:153326_AT dm
CHICKEN:GGA.8488.1.S1_S_AT NADH dehydrogenase (ubiquinone) flavoprotein 1, 51kDa gga
HG-U133_PLUS_2:208714_AT NADH dehydrogenase (ubiquinone) flavoprotein 1, 51kDa hs
HG-U133A:208714_AT NADH dehydrogenase (ubiquinone) flavoprotein 1, 51kDa hs
HG-FOCUS:208714_AT NADH dehydrogenase (ubiquinone) flavoprotein 1, 51kDa hs
HG-U133A_2:208714_AT NADH dehydrogenase (ubiquinone) flavoprotein 1, 51kDa hs
HU35KSUBA:RC_AA421781_AT NADH dehydrogenase (ubiquinone) flavoprotein 1, 51kDa hs
HU35KSUBA:HUM_ALU_AT NADH dehydrogenase (ubiquinone) flavoprotein 1, 51kDa hs
HU35KSUBB:HUM_ALU_AT NADH dehydrogenase (ubiquinone) flavoprotein 1, 51kDa hs
HU35KSUBC:HUM_ALU_AT NADH dehydrogenase (ubiquinone) flavoprotein 1, 51kDa hs
HU35KSUBD:HUM_ALU_AT NADH dehydrogenase (ubiquinone) flavoprotein 1, 51kDa hs
HUGENEFL:HUM_ALU_AT NADH dehydrogenase (ubiquinone) flavoprotein 1, 51kDa hs
HC-G110:HUM_ALU_AT NADH dehydrogenase (ubiquinone) flavoprotein 1, 51kDa hs
U133_X3P:G5138911_3P_AT NADH dehydrogenase (ubiquinone) flavoprotein 1, 51kDa hs
HG-U95AV2:37329_AT NADH dehydrogenase (ubiquinone) flavoprotein 1, 51kDa hs
HG-U133_PLUS_2:227795_AT NADH dehydrogenase (ubiquinone) flavoprotein 1, 51kDa hs
HG-U133B:227795_AT NADH dehydrogenase (ubiquinone) flavoprotein 1, 51kDa hs
HG-U95E:91569_AT NADH dehydrogenase (ubiquinone) flavoprotein 1, 51kDa hs
U133_X3P:HS.324151.0.A1_3P_AT NADH dehydrogenase (ubiquinone) flavoprotein 1, 51kDa hs
MOE430A:1415967_AT NADH dehydrogenase (ubiquinone) flavoprotein 1 mm
MOUSE430A_2:1415967_AT NADH dehydrogenase (ubiquinone) flavoprotein 1 mm
MOUSE430_2:1415967_AT NADH dehydrogenase (ubiquinone) flavoprotein 1 mm
MOE430A:1415966_A_AT NADH dehydrogenase (ubiquinone) flavoprotein 1 mm
MOUSE430A_2:1415966_A_AT NADH dehydrogenase (ubiquinone) flavoprotein 1 mm
MOUSE430_2:1415966_A_AT NADH dehydrogenase (ubiquinone) flavoprotein 1 mm
MU11KSUBB:Z31109_S_AT NADH dehydrogenase (ubiquinone) flavoprotein 1 mm
MG-U74AV2:96267_AT NADH dehydrogenase (ubiquinone) flavoprotein 1 mm
MOE430A:1456015_X_AT NADH dehydrogenase (ubiquinone) flavoprotein 1 mm
MOUSE430A_2:1456015_X_AT NADH dehydrogenase (ubiquinone) flavoprotein 1 mm
MOUSE430_2:1456015_X_AT NADH dehydrogenase (ubiquinone) flavoprotein 1 mm
MU19KSUBB:TC33346_AT NADH dehydrogenase (ubiquinone) flavoprotein 1 (Ndufv1), mRNA mm
MU19KSUBB:TC33346_G_AT NADH dehydrogenase (ubiquinone) flavoprotein 1 (Ndufv1), mRNA mm
MU19KSUBB:TC33347_AT NADH dehydrogenase (ubiquinone) flavoprotein 1 (Ndufv1), mRNA mm
RG-U34B:RC_AA901223_S_AT NADH dehydrogenase (ubiquinone) flavoprotein 1, 51kDa rn
RG-U34B:RC_AA901223_I_AT NADH dehydrogenase (ubiquinone) flavoprotein 1, 51kDa rn
RG-U34C:RC_AI103960_AT NADH dehydrogenase (ubiquinone) flavoprotein 1, 51kDa rn
RAE230A:1371416_AT NADH dehydrogenase (ubiquinone) flavoprotein 1, 51kDa rn
RAT230_2:1371416_AT NADH dehydrogenase (ubiquinone) flavoprotein 1, 51kDa rn
Gene Ontology
GO Biological Process (view graph)
ID Description Evidence Links
6120 mitochondrial electron transport, NADH to ubiquinone inferred from electronic annotation QuickGO AmiGO
GO Molecular Function (view graph)
ID Description Evidence Links
8137 NADH dehydrogenase (ubiquinone) activity inferred from electronic annotation QuickGO AmiGO
Protein Similarities
Method ID Description E-Value
blast CAA90435 Hypothetical protein C09H10.3 [Caenorhabditis elegans] ref|NP_496376.1| NADH Ubiquinone Oxidoreductase family member (nuo-1) [Caenorhabditis elegans] 0.0
blast CAE59572 Hypothetical protein CBG02970 [Caenorhabditis briggsae] 0.0
blast AAA30661 NADH dehydrogenase 0.0
blast XP_864381 PREDICTED: similar to NADH dehydrogenase (ubiquinone) flavoprotein 1, 51kDa isoform 7 [Canis familiaris] 0.0
Protein Domains
Database ID Description E-Value
Pfam IPR001949 EMBL-EBI Respiratory-chain NADH dehydrogenase, 51 kDa subunit 1.0E-126
Sequence
Target Sequence 
>C. ELEGANS:192049_AT
atcgcggaaccaagcttttctgcatctccggtcaagtcaacaatccatgcacggtcgaag
aagagatgtccgttccattgaaagatcttatcgagcgtcattgtggtggagtcatcggtg
gatgggataaccttcttgccatcattccaggaggatcttctgtcccacttatgccaaaga
acgtttgcgacacagttctcatggatttcgatgccctggttgctgctcaatctggtcttg
gaaccgccgcggttattgtgatgaacaagcaaactgatatcgttaaatgcatcgcccgat
tgtcacttttctataaacacgaatcttgcggacagtgtactccatgccgtgagggatgca
attggttgaacaagatgatgtggcgtttcgttgatggaaaagccaagccatcggagatcg
atatgatgtgggaacttagtaaacagatcgagggacacactatttgtgctcttggagacg
ctgctgcatggccagttcagggactcattcgccacttccgaccagaactcgaacgccgaa

BLASTn GenBank NR
Probe Info
Probe Sequence(5'-3') Probe X Probe Y Probe Interrogation
Position 		Strandedness
ATCGCGGAACCAAGCTTTTCTGCAT 442 37 854 Antisense
GCATCTCCGGTCAAGTCAACAATCC 645 309 875 Antisense
CATTCCAGGAGGATCTTCTGTCCCA 597 215 996 Antisense
AACGTTTGCGACACAGTTCTCATGG 230 145 1033 Antisense
TTCTCATGGATTTCGATGCCCTGGT 295 691 1049 Antisense
TGCTGCTCAATCTGGTCTTGGAACC 645 579 1074 Antisense
AAATGCATCGCCCGATTGTCACTTT 16 121 1138 Antisense
TTGCGGACAGTGTACTCCATGCCGT 710 699 1179 Antisense
ATTTGTGCTCTTGGAGACGCTGCTG 491 17 1315 Antisense
TGGCCAGTTCAGGGACTCATTCGCC 705 543 1342 Antisense
TTCCGACCAGAACTCGAACGCCGAA 480 695 1369 Antisense
Sequence Source Affymetrix Proprietary Database