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[192048_at] dipeptidyl aminopeptidase like

Description C27C12.7 /REP_DB=WormBase Gene ID /WP=CE05324 /TR=Q18253 /GB=CAA93743.1 /SUBMIT=HINXTON /CHR=X /FEA=Sanger Annotation /DEF=dipeptidyl aminopeptidase like
Cluster 6grp_highest_10_10 > 34      6grp_high1_10_10 > 43      4grp_high_8_8 > 44      6grp_highest_nonorm > 90      6grp_total > 21      4grp_total > 51      6grp_highest_sub > 02_03      6grp_cgc > 44      6grp_high1_sub > 02      6grp_cgc_sub > 02      6grp_total_sub > Hat      

Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 95
1 2 3 4 range
A 111.2
(0.2)
P 		155.5
(3)
P 		83.2
(-1.6)
P 		60.2
(-3)
A 		95
B 106.7
(0.3)
P 		125.9
(3)
P 		114.4
(1.4)
P 		83.9
(-3)
P 		42
C 120.3
(-1.5)
P 		120.9
(-1.3)
P 		140.3
(3)
P 		113.5
(-3)
P 		27
avr 112.7
(0.3) 		134.1
(3) 		112.6
(0.3) 		85.9
(-3) 		48

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 110
1 2 3 4 5 6 range
A 108.9
(-1.2)
P 		156.6
(2.3)
P 		163.9
(2.8)
P 		83.4
(-3)
P 		166.8
(3)
P 		101.8
(-1.7)
P 		83
B 124.3
(1.7)
P 		126.8
(2.2)
P 		125.2
(1.9)
P 		114.9
(-0.1)
P 		100.2
(-3)
P 		130.8
(3)
P 		31
C 138.5
(-0.1)
P 		193
(3)
P 		168.7
(1.6)
P 		149.5
(0.5)
P 		86.6
(-3)
P 		115.3
(-1.4)
P 		106
avr 123.9
(-1.9) 		158.8
(3) 		152.6
(2.1) 		115.9
(-3) 		117.9
(-2.7) 		116
(-3) 		43
No Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 40
1 2 3 4 range
A 40.5
(3)
P 		33.7
(1.7)
P 		21.7
(-0.6)
P 		8.8
(-3)
A 		32
B 34
(3)
P 		31.1
(1.9)
P 		26.5
(0.2)
P 		17.9
(-3)
P 		16
C 39.8
(1.2)
P 		34.8
(0.2)
P 		48.9
(3)
P 		19.1
(-3)
P 		30
avr 38.1
(3) 		33.2
(1.7) 		32.4
(1.5) 		15.3
(-3) 		23

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 39
1 2 3 4 5 6 range
A 20.1
(-3)
P 		55.7
(3)
P 		35.7
(-0.4)
P 		21.2
(-2.8)
P 		50.3
(2.1)
P 		24.8
(-2.2)
P 		36
B 43.2
(1.2)
P 		42.2
(0.8)
P 		30.4
(-3)
P 		30.4
(-3)
P 		40.7
(0.4)
P 		48.8
(3)
P 		18
C 51.3
(1.5)
P 		58.9
(3)
P 		42.9
(-0.1)
P 		30.1
(-2.6)
P 		28
(-3)
P 		38.6
(-0.9)
P 		31
avr 38.2
(-0.4) 		52.3
(3) 		36.3
(-0.8) 		27.2
(-3) 		39.7
(-0) 		37.4
(-0.6) 		25
NetAffx Links Cluster Members
Consensus/Exemplar
GeneChip Array Information
Probe Set ID 192048_at
GeneChip Array C. elegans Genome Array
Organism Common Name Nematode
Probe Design Information
Transcript ID(Array Design) affy.Ce.18027
Sequence Type Exemplar sequence
Representative Public ID C27C12.7 NCBI
Target Description C27C12.7 /REP_DB=WormBase Gene ID /WP=CE05324 /TR=Q18253 /GB=CAA93743.1 /SUBMIT=HINXTON /CHR=X /FEA=Sanger Annotation /DEF=dipeptidyl aminopeptidase like
Cluster Evidence This cluster is supported by a Sanger Annotation.
Annotation Method Description
Annotation Description This probe set was annotated using the Matching Probes based pipeline to a RefSeq identifier using 1 transcript(s).
Annotation Grade This is a grade A annotation.
Annotation Transcript Cluster (# of Matching Probes) NM_078060(11)
Transcript Assignments
Representative
Transcript		 Description Matching Probes Related Probesets by Grade
NM_078060 NCBI Caenorhabditis elegans Dipeptidyl Peptidase Four (IV) family member (dpf-2) (dpf-2) mRNA, complete cds. 11/11 None
GENEFINDER00000037263 ENSEMBL cdna:GeneFinder chromosome:CEL140:X:14830885:14838065:1 11/11 None
SNAP00000037254 ENSEMBL cdna:SNAP chromosome:CEL140:X:14833295:14838034:1 11/11 None
C27C12.7 ENSEMBL cdna:known chromosome:CEL140:X:14831742:14838100:1 gene:C27C12.7 11/11 None
Annotation Notes
There are no noteworthy cross hybridizing mRNAs found for this probe set.
Genomic Alignment of Consensus/Exemplar Sequence
Assembly Wormbase March 2004
Alignment(s)
Position Identity Coverage Cytoband
chrX:14831771-14838065(+) 100.0 100.0
Public Domain and Genome References
Gene Title dipeptidyl aminopeptidase like
Gene Symbol dpf-2
Ensembl C27C12.7
Entrez Gene 181579 Entrez gene
SwissProt Q18253 EMBL-EBI
WormBase CE05324 Wormbase
Functional Annotations
Ortholog
ID Title Organism
CANINE_2:CFA.19079.1.S1_S_AT similar to fibroblast activation protein, alpha subunit cfa
CANINE_2:CFAAFFX.16274.1.S1_AT similar to fibroblast activation protein, alpha subunit cfa
DROSOPHILA_2:1640918_AT omega dm
DROSGENOME1:154049_AT omega dm
CHICKEN:GGA.10098.1.S1_S_AT fibroblast activation protein, alpha gga
CHICKEN:GGAAFFX.23453.2.S1_S_AT fibroblast activation protein, alpha gga
HG-U133_PLUS_2:209955_S_AT fibroblast activation protein, alpha hs
HG-U133A:209955_S_AT fibroblast activation protein, alpha hs
HG-FOCUS:209955_S_AT fibroblast activation protein, alpha hs
HG-U133A_2:209955_S_AT fibroblast activation protein, alpha hs
HU35KSUBD:RC_AA405569_S_AT fibroblast activation protein, alpha hs
HU35KSUBD:RC_AA436611_S_AT fibroblast activation protein, alpha hs
HUGENEFL:U09278_AT fibroblast activation protein, alpha hs
U133_X3P:G1924981_3P_A_AT fibroblast activation protein, alpha hs
HG-U95AV2:39945_AT fibroblast activation protein, alpha hs
HG-U95C:52989_AT Fibroblast activation protein, alpha hs
HG-U95D:84780_AT Fibroblast activation protein, alpha hs
MOUSE430_2:1417552_AT fibroblast activation protein mm
MOE430A:1417552_AT fibroblast activation protein mm
MOUSE430A_2:1417552_AT fibroblast activation protein mm
MG-U74AV2:92441_AT fibroblast activation protein mm
RAE230A:1369422_AT fibroblast activation protein rn
RAT230_2:1369422_AT fibroblast activation protein rn
Gene Ontology
GO Biological Process (view graph)
ID Description Evidence Links
6508 proteolysis inferred from electronic annotation QuickGO AmiGO
GO Cellular Component (view graph)
ID Description Evidence Links
16020 membrane inferred from electronic annotation QuickGO AmiGO
GO Molecular Function (view graph)
ID Description Evidence Links
3824 catalytic activity inferred from electronic annotation QuickGO AmiGO
4274 dipeptidyl-peptidase IV activity inferred from electronic annotation QuickGO AmiGO
8236 serine-type peptidase activity inferred from electronic annotation QuickGO AmiGO
Protein Similarities
Method ID Description E-Value
blast CAA93743 Hypothetical protein C27C12.7 [Caenorhabditis elegans] ref|NP_510461.1| Dipeptidyl Peptidase Four (IV) family member (dpf-2) [Caenorhabditis elegans] 0.0
blast CAE63236 Hypothetical protein CBG07598 [Caenorhabditis briggsae] 0.0
blast CAE56836 Hypothetical protein CBG24661 [Caenorhabditis briggsae] 1.0E-79
Protein Domains
Database ID Description E-Value
Pfam IPR001375 EMBL-EBI Peptidase S9, prolyl oligopeptidase active site region 5.0E-12
Pfam IPR002469 EMBL-EBI Peptidase S9B, dipeptidylpeptidase IV N-terminal 1.0E-126
Pfam IPR001375 EMBL-EBI Peptidase S9, prolyl oligopeptidase active site region 5.0E-12
Pfam IPR002469 EMBL-EBI Peptidase S9B, dipeptidylpeptidase IV N-terminal 1.0E-126
Pfam IPR001375 EMBL-EBI Peptidase S9, prolyl oligopeptidase active site region 5.0E-12
Pfam IPR002469 EMBL-EBI Peptidase S9B, dipeptidylpeptidase IV N-terminal 1.0E-126
Trans Membrane
ID Number Of Domains Domain Boundaries
NP_510461.1 1 21-43
C27C12.7 1 21-43
GENEFINDER00000037263 1 74-96
Sequence
Target Sequence 
>C. ELEGANS:192048_AT
gcaagaattgacgttcgtggaactggaggacgaggttgggatgtgaaagaagcggtgtat
cgaaagctaggtgatgctgaggttgttgacactctggatatgattagagcatttattaat
actttcgggtttattgacgaagatcggatagcagtcatgggatggtcgtacggtggcttt
ttgacgtcgaaaattgctatcaaagatcaaggagaattggtaaaatgtgcgatatcaatt
gcaccagtcactgatttcaaatactatgactctgcctacaccgaaagatacct

BLASTn GenBank NR
Probe Info
Probe Sequence(5'-3') Probe X Probe Y Probe Interrogation
Position 		Strandedness
GCAAGAATTGACGTTCGTGGAACTG 213 315 1918 Antisense
ACTGGAGGACGAGGTTGGGATGTGA 666 95 1939 Antisense
GCTAGGTGATGCTGAGGTTGTTGAC 140 303 1983 Antisense
GGTTGTTGACACTCTGGATATGATT 257 507 1998 Antisense
GAGCATTTATTAATACTTTCGGGTT 35 387 2024 Antisense
CGAAGATCGGATAGCAGTCATGGGA 396 251 2055 Antisense
AGTCATGGGATGGTCGTACGGTGGC 353 59 2070 Antisense
TCGTACGGTGGCTTTTTGACGTCGA 54 599 2083 Antisense
GCGATATCAATTGCACCAGTCACTG 65 291 2146 Antisense
GCACCAGTCACTGATTTCAAATACT 299 313 2158 Antisense
ACTCTGCCTACACCGAAAGATACCT 495 99 2186 Antisense
Sequence Source Affymetrix Proprietary Database