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[192040_s_at] myosin heavy chain C

Description T18D3.4 /REP_DB=WormBase Gene ID /WP=CE03665 /GEN=myo-2 /TR=Q20439 /GB=CAA92197.1 /SUBMIT=HINXTON /CHR=X /FEA=Sanger Annotation /DEF=myosin heavy chain C
Cluster 6grp_highest_10_10 > 51      6grp_high1_10_10 > 16      4grp_highest_8_8 > 58      4grp_high_8_8 > 33      6grp_highest_nonorm > 02      6grp_total > 16      4grp_total > 46      6grp_highest_sub > De      6grp_cgc > 22      6grp_high1_sub > De      6grp_cgc_sub > De      6grp_total_sub > Decrease      6grp_rule_based > S1      4grp_rule_based > L1      

Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 5685
1 2 3 4 range
A 6693
(3)
P 		2741.5
(-1.2)
P 		1007.6
(-3)
P 		1520.5
(-2.5)
P 		5685
B 6626.4
(3)
P 		2467.2
(-1.5)
P 		1074.2
(-3)
P 		1918.9
(-2.1)
P 		5552
C 5842.2
(3)
P 		2209.2
(-1.7)
P 		1215.1
(-3)
P 		1400.7
(-2.8)
P 		4627
avr 6387.2
(3) 		2472.6
(-1.4) 		1099
(-3) 		1613.4
(-2.4) 		5288

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 4860
1 2 3 4 5 6 range
A 5144.7
(3)
P 		4277.9
(1.8)
P 		1289.9
(-2.1)
P 		894.3
(-2.6)
P 		656.1
(-3)
P 		631
(-3)
P 		4514
B 5279
(3)
P 		3766.5
(1)
P 		1536.4
(-1.9)
P 		960
(-2.7)
P 		890.7
(-2.8)
P 		704.3
(-3)
P 		4575
C 5491.1
(3)
P 		3548.7
(0.6)
P 		2253.8
(-1)
P 		1239
(-2.3)
P 		1318.1
(-2.2)
P 		645.5
(-3)
P 		4846
avr 5304.9
(3) 		3864.4
(1.1) 		1693.4
(-1.7) 		1031.1
(-2.5) 		955
(-2.6) 		660.3
(-3) 		4645
No Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 2214
1 2 3 4 range
A 2436.9
(3)
P 		595.1
(-2)
P 		263.4
(-2.9)
P 		222.6
(-3)
P 		2214
B 2113.1
(3)
P 		609.3
(-1.8)
P 		248.9
(-3)
P 		408.9
(-2.5)
P 		1864
C 1933.9
(3)
P 		635.1
(-1.6)
P 		423.5
(-2.3)
P 		236.2
(-3)
P 		1698
avr 2161.3
(3) 		613.2
(-2) 		311.9
(-2.9) 		289.2
(-3) 		1872

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 1882
1 2 3 4 5 6 range
A 948.4
(0.5)
P 		1521.4
(3)
P 		280.9
(-2.4)
P 		226.8
(-2.7)
P 		198
(-2.8)
P 		153.6
(-3)
P 		1368
B 1836.8
(3)
P 		1253.7
(0.8)
P 		373.1
(-2.5)
P 		254.3
(-3)
P 		361.9
(-2.6)
P 		262.6
(-3)
P 		1583
C 2035.3
(3)
P 		1082.8
(-0.1)
P 		573.6
(-1.8)
P 		249.2
(-2.9)
P 		426.5
(-2.3)
P 		216.1
(-3)
P 		1819
avr 1606.8
(3) 		1286
(1.6) 		409.2
(-2.1) 		243.4
(-2.9) 		328.8
(-2.5) 		210.8
(-3) 		1396
NetAffx Links Cluster Members
Consensus/Exemplar
Group Members
GeneChip Array Information
Probe Set ID 192040_s_at
GeneChip Array C. elegans Genome Array
Organism Common Name Nematode
Probe Design Information
Transcript ID(Array Design) affy.Ce.16883
Sequence Type Exemplar sequence
Representative Public ID T18D3.4 NCBI
Target Description T18D3.4 /REP_DB=WormBase Gene ID /WP=CE03665 /GEN=myo-2 /TR=Q20439 /GB=CAA92197.1 /SUBMIT=HINXTON /CHR=X /FEA=Sanger Annotation /DEF=myosin heavy chain C
Cluster Evidence This cluster is supported by a Sanger Annotation.
Annotation Method Description
Annotation Description This probe set was annotated using the Genome Target Overlap based pipeline to a RefSeq identifier using 1 transcript(s).
Annotation Grade This is a grade B annotation.
Annotation Transcript Cluster (# of Matching Probes) NM_077691
Transcript Assignments
Representative
Transcript		 Description Matching Probes Related Probesets by Grade
T18D3.4 ENSEMBL cdna:known chromosome:CEL140:X:12467982:12475262:1 gene:T18D3.4 None
SNAP00000017820 ENSEMBL cdna:SNAP chromosome:CEL140:X:12470340:12474867:1 None
NM_077691 NCBI Caenorhabditis elegans MYOsin heavy chain structural genes family member (myo-2) (myo-2) mRNA, complete cds. None
GENEFINDER00000017828 ENSEMBL cdna:GeneFinder chromosome:CEL140:X:12470400:12474867:1 None
Annotation Notes
There are no noteworthy cross hybridizing mRNAs found for this probe set.
Genomic Alignment of Consensus/Exemplar Sequence
Assembly Wormbase March 2004
Alignment(s)
Position Identity Coverage Cytoband
chrX:12468069-12474867(+) 100.0 100.0
Public Domain and Genome References
Gene Title myosin heavy chain C
Gene Symbol myo-2
Ensembl T18D3.4
Entrez Gene 181404 Entrez gene
SwissProt P12845 EMBL-EBI
WormBase CE31619 Wormbase
Functional Annotations
Ortholog
ID Title Organism
CANINE:1605998_AT myosin, heavy polypeptide 6, cardiac muscle, alpha (cardiomyopathy, hypertrophic 1) cfa
CANINE:1605929_AT myosin, heavy polypeptide 6, cardiac muscle, alpha (cardiomyopathy, hypertrophic 1) cfa
CANINE:1604415_S_AT myosin, heavy polypeptide 6, cardiac muscle, alpha (cardiomyopathy, hypertrophic 1) cfa
CANINE:1604094_AT myosin, heavy polypeptide 6, cardiac muscle, alpha (cardiomyopathy, hypertrophic 1) cfa
CANINE:1599597_AT myosin, heavy polypeptide 6, cardiac muscle, alpha (cardiomyopathy, hypertrophic 1) cfa
CANINE:1592346_S_AT myosin, heavy polypeptide 6, cardiac muscle, alpha (cardiomyopathy, hypertrophic 1) cfa
CANINE:1591548_AT myosin, heavy polypeptide 6, cardiac muscle, alpha (cardiomyopathy, hypertrophic 1) cfa
CANINE_2:CFA.3668.1.S1_S_AT myosin, heavy polypeptide 6, cardiac muscle, alpha (cardiomyopathy, hypertrophic 1) cfa
CANINE_2:CFA.4486.1.S1_AT myosin, heavy polypeptide 6, cardiac muscle, alpha (cardiomyopathy, hypertrophic 1) cfa
CANINE_2:CFAAFFX.18058.1.S1_AT myosin, heavy polypeptide 6, cardiac muscle, alpha (cardiomyopathy, hypertrophic 1) cfa
CANINE_2:CFAAFFX.18058.1.S1_S_AT myosin, heavy polypeptide 6, cardiac muscle, alpha (cardiomyopathy, hypertrophic 1) cfa
CANINE_2:CFAAFFX.18065.1.S1_S_AT myosin, heavy polypeptide 6, cardiac muscle, alpha (cardiomyopathy, hypertrophic 1) cfa
CANINE:1593934_AT Slow myosin heavy chain cfa
CHICKEN:GGA.2617.1.S1_AT myosin, heavy polypeptide 6, cardiac muscle, alpha (cardiomyopathy, hypertrophic 1) gga
HG-U133A:204737_S_AT myosin, heavy polypeptide 6, cardiac muscle, alpha (cardiomyopathy, hypertrophic 1) hs
HG-FOCUS:204737_S_AT myosin, heavy polypeptide 6, cardiac muscle, alpha (cardiomyopathy, hypertrophic 1) hs
HG-U133_PLUS_2:204737_S_AT myosin, heavy polypeptide 6, cardiac muscle, alpha (cardiomyopathy, hypertrophic 1) hs
HG-U133A_2:204737_S_AT myosin, heavy polypeptide 6, cardiac muscle, alpha (cardiomyopathy, hypertrophic 1) hs
HG-U133_PLUS_2:214468_AT myosin, heavy polypeptide 6, cardiac muscle, alpha (cardiomyopathy, hypertrophic 1) hs
HG-U133A_2:214468_AT myosin, heavy polypeptide 6, cardiac muscle, alpha (cardiomyopathy, hypertrophic 1) hs
HG-U133A:214468_AT myosin, heavy polypeptide 6, cardiac muscle, alpha (cardiomyopathy, hypertrophic 1) hs
HG-U95AV2:38602_AT myosin, heavy polypeptide 6, cardiac muscle, alpha (cardiomyopathy, hypertrophic 1) hs
HUGENEFL:Z20656_RNA1_S_AT myosin, heavy polypeptide 6, cardiac muscle, alpha (cardiomyopathy, hypertrophic 1) hs
U133_X3P:HS.278432.0.S1_3P_AT myosin, heavy polypeptide 6, cardiac muscle, alpha (cardiomyopathy, hypertrophic 1) hs
MU11KSUBA:M76601_F_AT myosin, heavy polypeptide 6, cardiac muscle, alpha mm
MU11KSUBB:MSA.400.0_F_AT myosin, heavy polypeptide 6, cardiac muscle, alpha mm
MG-U74AV2:101071_AT myosin, heavy polypeptide 6, cardiac muscle, alpha mm
MOE430A:1448554_S_AT myosin, heavy polypeptide 6, cardiac muscle, alpha mm
MOUSE430A_2:1448554_S_AT myosin, heavy polypeptide 6, cardiac muscle, alpha mm
MOUSE430_2:1448554_S_AT myosin, heavy polypeptide 6, cardiac muscle, alpha mm
MOE430A:1448827_S_AT myosin, heavy polypeptide 6, cardiac muscle, alpha mm
MOUSE430A_2:1448827_S_AT myosin, heavy polypeptide 6, cardiac muscle, alpha mm
MOUSE430_2:1448827_S_AT myosin, heavy polypeptide 6, cardiac muscle, alpha mm
MOE430A:1448826_AT myosin, heavy polypeptide 6, cardiac muscle, alpha mm
MOUSE430A_2:1448826_AT myosin, heavy polypeptide 6, cardiac muscle, alpha mm
MOUSE430_2:1448826_AT myosin, heavy polypeptide 6, cardiac muscle, alpha mm
MOE430A:1417729_AT myosin, heavy polypeptide 6, cardiac muscle, alpha mm
MOUSE430A_2:1417729_AT myosin, heavy polypeptide 6, cardiac muscle, alpha mm
MOUSE430_2:1417729_AT myosin, heavy polypeptide 6, cardiac muscle, alpha mm
MU19KSUBA:TC16074_AT Myosin, heavy polypeptide 6, cardiac muscle, alpha (Myh6), mRNA mm
MU19KSUBA:TC16659_S_AT Myosin, heavy polypeptide 6, cardiac muscle, alpha (Myh6), mRNA mm
MU19KSUBA:TC24908_AT Myosin, heavy polypeptide 6, cardiac muscle, alpha (Myh6), mRNA mm
MU19KSUBA:TC25362_AT Myosin, heavy polypeptide 6, cardiac muscle, alpha (Myh6), mRNA mm
MU19KSUBC:TC38654_S_AT Myosin, heavy polypeptide 6, cardiac muscle, alpha (Myh6), mRNA mm
MU19KSUBC:TC40847_F_AT Myosin, heavy polypeptide 6, cardiac muscle, alpha (Myh6), mRNA mm
RG-U34A:X15939_R_AT myosin heavy chain, polypeptide 6 rn
RG-U34A:RC_AI103920_F_AT myosin heavy chain, polypeptide 6 rn
RG-U34A:RC_AI104924_F_AT myosin heavy chain, polypeptide 6 rn
RG-U34A:RC_AA891522_F_AT myosin heavy chain, polypeptide 6 rn
RG-U34C:RC_AA819464_AT myosin heavy chain, polypeptide 6 rn
RG-U34C:RC_AI232024_F_AT myosin heavy chain, polypeptide 6 rn
RAE230A:1387049_AT myosin heavy chain, polypeptide 6 rn
RAT230_2:1387049_AT myosin heavy chain, polypeptide 6 rn
RAE230A:1368093_AT myosin heavy chain, polypeptide 6 rn
RAT230_2:1368093_AT myosin heavy chain, polypeptide 6 rn
RAE230A:1398248_S_AT myosin heavy chain, polypeptide 6 rn
RAT230_2:1398248_S_AT myosin heavy chain, polypeptide 6 rn
RAE230B:1393540_AT Myosin heavy chain, polypeptide 6 rn
RAT230_2:1393540_AT Myosin heavy chain, polypeptide 6 rn
RAE230B:1396165_AT Myosin heavy chain, polypeptide 6 rn
RAT230_2:1396165_AT Myosin heavy chain, polypeptide 6 rn
RG-U34B:RC_AA924346_AT Myosin heavy chain, polypeptide 6 rn
RG-U34B:RC_AI009388_AT Myosin heavy chain, polypeptide 6 rn
Gene Ontology
GO Biological Process (view graph)
ID Description Evidence Links
6508 proteolysis inferred from electronic annotation QuickGO AmiGO
GO Cellular Component (view graph)
ID Description Evidence Links
16459 myosin inferred from electronic annotation QuickGO AmiGO
16460 myosin II inferred from sequence similarity QuickGO AmiGO
GO Molecular Function (view graph)
ID Description Evidence Links
3774 motor activity inferred from electronic annotation QuickGO AmiGO
4289 subtilase activity inferred from electronic annotation QuickGO AmiGO
5524 ATP binding inferred from electronic annotation QuickGO AmiGO
Protein Similarities
Method ID Description E-Value
blast CAA92183 Hypothetical protein T18D3.4 [Caenorhabditis elegans] emb|CAA92197.2| Hypothetical protein T18D3.4 [Caenorhabditis elegans] ref|NP_510092.2| MYOsin heavy chain structural genes family member (myo-2) [Caenorhabditis elegans] sp|P12845|MYO2_CAEEL Myosin-2 (Myosin heavy chain C) (MHC C) 0.0
blast CAA30855 myosin heavy chain 2 [Caenorhabditis elegans] 0.0
blast CAE57242 Hypothetical protein CBG00120 [Caenorhabditis briggsae] 0.0
Protein Domains
Database ID Description E-Value
scop a.2.7.Methicillin resistance protein FemA probable tRNA-binding arm All alpha proteins; Long alpha-hairpin; tRNA-binding arm; Methicillin resistance protein FemA probable tRNA-binding arm 3.40000009536743
Pfam IPR004009 EMBL-EBI Myosin N-terminal SH3-like domain 1.1E-18
Pfam IPR001609 EMBL-EBI Myosin head (motor domain) 1.0E-126
Pfam IPR002928 EMBL-EBI Myosin tail 1.0E-126
Pfam IPR001609 EMBL-EBI Myosin head (motor domain) 5.1E-102
Pfam IPR002928 EMBL-EBI Myosin tail 1.0E-126
Pfam IPR001609 EMBL-EBI Myosin head (motor domain) 2.2E-93
Pfam IPR002928 EMBL-EBI Myosin tail 1.0E-126
Sequence
Target Sequence 
>C. ELEGANS:192040_S_AT
atccgaagaccgtggacgtcgtgctgccagcgacgccgccaaacttgctgaggacctccg
ccacgagcaagagcaatctcaacaacttgagagattcaagaaacaacttgaaagcgctgt
caagagtgtgcatcttttcccaccgtcgcaactacttatccttttgcgcgtcacagattt
aaagattgatctccaagagcgtgccgacgccgctgaggcagctgtcatgaagggaggagc
caaggcaatccagaaggctgagcaacgtctgaaagccttccagagtgacttggaaaccga
gagccgtcgcgccggagaagcatccaagacccttgctcgtgctgaccgcaaggtccgcga
gttcgagttccaggttgctgaggacaagaagaactacgataagctccaagaattagttga
gaaactcacagccaagctcaagctccagaagaagcaactcgaggaagctgaggagcaagc
taacagccatcttagcaagtacagaaccgtccaactttcccttgaaaccgctgaagagag
agccgattccgctgagcaatgtc

BLASTn GenBank NR
Probe Info
Probe Sequence(5'-3') Probe X Probe Y Probe Interrogation
Position 		Strandedness
ATCCGAAGACCGTGGACGTCGTGCT 75 3 5310 Antisense
CCTCCGCCACGAGCAAGAGCAATCT 502 267 5364 Antisense
CCGTCGCAACTACTTATCCTTTTGC 507 265 5452 Antisense
TATCCTTTTGCGCGTCACAGATTTA 316 657 5466 Antisense
GATTGATCTCCAAGAGCGTGCCGAC 525 433 5493 Antisense
CTGAGCAACGTCTGAAAGCCTTCCA 235 227 5567 Antisense
TGACCGCAAGGTCCGCGAGTTCGAG 578 553 5652 Antisense
CGAGTTCGAGTTCCAGGTTGCTGAG 122 243 5667 Antisense
GAAACTCACAGCCAAGCTCAAGCTC 462 357 5730 Antisense
CAACTTTCCCTTGAAACCGCTGAAG 673 93 5821 Antisense
AGAGCCGATTCCGCTGAGCAATGTC 106 71 5848 Antisense
Sequence Source Affymetrix Proprietary Database