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[192032_s_at] protein disulfide-isomerase

Description B0403.4 /REP_DB=WormBase Gene ID /WP=CE03880 /TR=SW:Q11067 /GB=AAC47065.1 /SUBMIT=ST.LOUIS /CHR=X /FEA=Sanger Annotation /DEF=protein disulfide-isomerase
Cluster 6grp_highest_10_10 > 02      6grp_high1_10_10 > 11      4grp_highest_8_8 > 09      4grp_high_8_8 > 54      6grp_highest_nonorm > 05      6grp_total > 23      4grp_total > 58      6grp_cgc > 70      6grp_high1_sub > De      6grp_total_sub > Decrease      4grp_rule_based > L3      

Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 7497
1 2 3 4 range
A 5536.7
(-1)
P 		9156.5
(2)
P 		10357.2
(3)
P 		3153.7
(-3)
P 		7204
B 5213.4
(-1.5)
P 		9486.7
(2.1)
P 		10572.2
(3)
P 		3458.2
(-3)
P 		7114
C 5435
(-0.6)
P 		8987.6
(3)
P 		8863.2
(2.9)
P 		3075.2
(-3)
P 		5912
avr 5395
(-1.1) 		9210.3
(2.4) 		9930.9
(3) 		3229
(-3) 		6702

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 7078
1 2 3 4 5 6 range
A 10055.7
(3)
P 		7232.5
(0.2)
P 		6642.6
(-0.4)
P 		6031.5
(-1)
P 		5120.4
(-1.9)
P 		4060.8
(-3)
P 		5995
B 8833.1
(3)
P 		7283
(1.3)
P 		8490.1
(2.6)
P 		6214
(0.2)
P 		5018.7
(-1.1)
P 		3289.3
(-3)
P 		5544
C 8145.5
(3)
P 		7064.8
(1.7)
P 		7789.7
(2.6)
P 		6351.2
(0.9)
P 		5150
(-0.5)
P 		2977.3
(-3)
P 		5168
avr 9011.4
(3) 		7193.4
(1) 		7640.8
(1.5) 		6198.9
(-0) 		5096.4
(-1.2) 		3442.5
(-3) 		5569
No Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 2628
1 2 3 4 range
A 2015.9
(1.2)
P 		1987.6
(1.1)
P 		2707.6
(3)
P 		461.6
(-3)
P 		2246
B 1662.5
(0.2)
P 		2343
(2.6)
P 		2449.8
(3)
P 		736.9
(-3)
P 		1713
C 1799.1
(-0)
P 		2584
(1.8)
P 		3089.1
(3)
P 		518.5
(-3)
P 		2571
avr 1825.8
(0.5) 		2304.9
(1.8) 		2748.8
(3) 		572.3
(-3) 		2177

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 2085
1 2 3 4 5 6 range
A 1853.7
(0.3)
P 		2572.2
(3)
P 		1446.6
(-1.3)
P 		1529.7
(-1)
P 		1545.1
(-0.9)
P 		988.7
(-3)
P 		1584
B 3073.5
(3)
P 		2424.2
(0.9)
P 		2061.6
(-0.3)
P 		1645.9
(-1.6)
P 		2039
(-0.4)
P 		1226.6
(-3)
P 		1847
C 3019.2
(3)
P 		2155.7
(0.4)
P 		1982.6
(-0.1)
P 		1277.2
(-2.2)
P 		1666.5
(-1)
P 		996.7
(-3)
P 		2023
avr 2648.8
(3) 		2384
(2) 		1830.3
(-0.1) 		1484.3
(-1.4) 		1750.2
(-0.4) 		1070.7
(-3) 		1578
NetAffx Links Cluster Members
Consensus/Exemplar
Group Members
GeneChip Array Information
Probe Set ID 192032_s_at
GeneChip Array C. elegans Genome Array
Organism Common Name Nematode
Probe Design Information
Transcript ID(Array Design) affy.Ce.16873
Sequence Type Exemplar sequence
Representative Public ID B0403.4 NCBI
Target Description B0403.4 /REP_DB=WormBase Gene ID /WP=CE03880 /TR=SW:Q11067 /GB=AAC47065.1 /SUBMIT=ST.LOUIS /CHR=X /FEA=Sanger Annotation /DEF=protein disulfide-isomerase
Cluster Evidence This cluster is supported by a Sanger Annotation.
Annotation Method Description
Annotation Description This probe set was annotated using the Matching Probes based pipeline to a RefSeq identifier using 1 transcript(s).
Annotation Grade This is a grade A annotation.
Annotation Transcript Cluster (# of Matching Probes) NM_076789(11)
Transcript Assignments
Representative
Transcript		 Description Matching Probes Related Probesets by Grade
NM_076789 NCBI Caenorhabditis elegans Temporarily Assigned Gene name family member (tag-320) (tag-320) mRNA, complete cds. 11/11 None
SNAP00000026986 ENSEMBL cdna:SNAP chromosome:CEL140:X:7066486:7068387:-1 11/11 None
GENEFINDER00000026992 ENSEMBL cdna:GeneFinder chromosome:CEL140:X:7066486:7068387:-1 11/11 None
B0403.4 ENSEMBL cdna:known chromosome:CEL140:X:7066292:7068510:-1 gene:B0403.4 11/11 A 
Annotation Notes
There are no noteworthy cross hybridizing mRNAs found for this probe set.
Genomic Alignment of Consensus/Exemplar Sequence
Assembly Wormbase March 2004
Alignment(s)
Position Identity Coverage Cytoband
chrX:7066484-7068386(-) 100.0 100.0
Public Domain and Genome References
Gene Title protein disulfide-isomerase
Gene Symbol tag-320
Ensembl B0403.4
Entrez Gene 180974 Entrez gene
SwissProt Q11067 EMBL-EBI
WormBase CE03880 Wormbase
Functional Annotations
Ortholog
ID Title Organism
ATH1-121501:261167_AT thioredoxin family protein at
CANINE:1583126_AT similar to Protein disulfide-isomerase A6 precursor (Thioredoxin domain containing protein 7) cfa
CANINE_2:CFA.20823.1.S1_S_AT similar to Protein disulfide-isomerase A6 precursor (Thioredoxin domain containing protein 7) cfa
CANINE_2:CFA.5563.1.A1_S_AT similar to Protein disulfide-isomerase A6 precursor (Thioredoxin domain containing protein 7) cfa
CANINE_2:CFAAFFX.6163.1.S1_AT similar to Protein disulfide-isomerase A6 precursor (Thioredoxin domain containing protein 7) cfa
CANINE_2:CFAAFFX.6163.1.S1_S_AT similar to Protein disulfide-isomerase A6 precursor (Thioredoxin domain containing protein 7) cfa
DROSOPHILA_2:1626196_AT dm
DROSGENOME1:154419_AT dm
CHICKEN:GGAAFFX.24959.1.S1_AT protein disulfide isomerase family A, member 6 gga
HG-U133_PLUS_2:208639_X_AT protein disulfide isomerase family A, member 6 hs
HG-U133A:208639_X_AT protein disulfide isomerase family A, member 6 hs
HG-U133A_2:208639_X_AT protein disulfide isomerase family A, member 6 hs
HG-U133_PLUS_2:200915_X_AT protein disulfide isomerase family A, member 6 hs
HG-U133A:200915_X_AT protein disulfide isomerase family A, member 6 hs
HG-U133A_2:200915_X_AT protein disulfide isomerase family A, member 6 hs
HG-U133_PLUS_2:214709_S_AT protein disulfide isomerase family A, member 6 hs
HG-U133A_2:214709_S_AT protein disulfide isomerase family A, member 6 hs
HG-FOCUS:214709_S_AT protein disulfide isomerase family A, member 6 hs
HG-U133A:214709_S_AT protein disulfide isomerase family A, member 6 hs
HG-U133_PLUS_2:207668_X_AT protein disulfide isomerase family A, member 6 hs
HG-U133A:207668_X_AT protein disulfide isomerase family A, member 6 hs
HG-U133A_2:207668_X_AT protein disulfide isomerase family A, member 6 hs
HG-U133_PLUS_2:208638_AT protein disulfide isomerase family A, member 6 hs
HG-U133A_2:208638_AT protein disulfide isomerase family A, member 6 hs
HG-FOCUS:208638_AT protein disulfide isomerase family A, member 6 hs
HG-U133A:208638_AT protein disulfide isomerase family A, member 6 hs
HUGENEFL:Z22551_AT protein disulfide isomerase family A, member 6 hs
HUGENEFL:D49489_AT protein disulfide isomerase family A, member 6 hs
U133_X3P:G4826813_3P_X_AT protein disulfide isomerase family A, member 6 hs
U133_X3P:G4826813_3P_A_AT protein disulfide isomerase family A, member 6 hs
U133_X3P:HS.211577.1.S1_3P_A_AT protein disulfide isomerase family A, member 6 hs
U133_X3P:HS.182429.2.S1_3P_A_AT protein disulfide isomerase family A, member 6 hs
U133_X3P:HS.182429.1.S2_3P_AT protein disulfide isomerase family A, member 6 hs
HG-U133A_2:216640_S_AT protein disulfide isomerase family A, member 6 hs
HG-U133_PLUS_2:216640_S_AT protein disulfide isomerase family A, member 6 hs
HG-U133A:216640_S_AT protein disulfide isomerase family A, member 6 hs
HG-U95AV2:32846_S_AT protein disulfide isomerase family A, member 6 hs
HG-U95AV2:41750_AT protein disulfide isomerase family A, member 6 hs
HG-U95D:74808_S_AT protein disulfide isomerase family A, member 6 hs
HG-U95AV2:41751_AT protein disulfide isomerase family A, member 6 hs
HG-U95D:79104_R_AT Protein disulfide isomerase family A, member 6 hs
MOUSE430_2:1423648_AT protein disulfide isomerase associated 6 mm
MOUSE430A_2:1423648_AT protein disulfide isomerase associated 6 mm
MOE430A:1423648_AT protein disulfide isomerase associated 6 mm
MU11KSUBA:AA103744_F_AT protein disulfide isomerase associated 6 mm
MG-U74AV2:94207_AT protein disulfide isomerase associated 6 mm
MG-U74AV2:94209_G_AT protein disulfide isomerase associated 6 mm
MG-U74AV2:94208_AT protein disulfide isomerase associated 6 mm
MOE430A:1430983_AT protein disulfide isomerase associated 6 mm
MOUSE430A_2:1430983_AT protein disulfide isomerase associated 6 mm
MOUSE430_2:1430983_AT protein disulfide isomerase associated 6 mm
MU19KSUBA:TC18649_AT Protein disulfide isomerase associated 6, mRNA (cDNA clone MGC:6472 IMAGE:2645183) mm
MU19KSUBB:TC32907_S_AT Protein disulfide isomerase associated 6, mRNA (cDNA clone MGC:6472 IMAGE:2645183) mm
MU19KSUBC:TC41849_AT Protein disulfide isomerase associated 6, mRNA (cDNA clone MGC:6472 IMAGE:2645183) mm
RT-U34:RC_AA892532_AT thioredoxin domain containing 7 rn
RG-U34A:RC_AA892532_AT thioredoxin domain containing 7 rn
RAE230A:1370859_AT thioredoxin domain containing 7 rn
RAT230_2:1370859_AT thioredoxin domain containing 7 rn
Gene Ontology
GO Biological Process (view graph)
ID Description Evidence Links
6118 electron transport inferred from electronic annotation QuickGO AmiGO
GO Molecular Function (view graph)
ID Description Evidence Links
5489 electron transporter activity inferred from electronic annotation QuickGO AmiGO
16853 isomerase activity inferred from electronic annotation QuickGO AmiGO
Protein Similarities
Method ID Description E-Value
blast AAC47065 Temporarily assigned gene name protein 320 [Caenorhabditis elegans] ref|NP_509190.1| Temporarily Assigned Gene name family member (tag-320) [Caenorhabditis elegans] sp|Q11067|PDIA6_CAEEL Probable protein disulfide-isomerase A6 precursor 0.0
blast CAE65837 Hypothetical protein CBG10962 [Caenorhabditis briggsae] 0.0
blast AAF53532 CG5809-PA [Drosophila melanogaster] ref|NP_609792.1| CG5809-PA [Drosophila melanogaster] gb|AAL28897.1| LD28038p [Drosophila melanogaster] gb|AAF45013.1| symbol=BG:DS09218.4; cDNA=method:''sim4'', score:''1000.0'', desc:''LD05503 LD Drosophila melanogaster embryo BlueScript Drosophila melanogaster cDNA clone, full length mRNA sequence from BDGP''; match=method:''BLASTX'', version:''2.0a19MP-WashU [05-Feb-1998] [Build sol2.5-ultra 01:47:30 05-Feb-1998]'', score:''1420.0'', desc:''SwissProt::Q11067:PROBABLE PROTEIN DISULFIDE ISOMERASE P5 PRECURSOR (EC 5.3.4.1). organism:CAENORHABDITIS ELEGANS. dbxref:EMBL; U40411; g1065461; -. WORMPEP; B0403.4; CE03880. PROS> 1.0E-140
Protein Domains
Database ID Description E-Value
Pfam IPR006662 EMBL-EBI Thioredoxin type domain 1.1E-39
Pfam IPR006662 EMBL-EBI Thioredoxin type domain 6.1E-44
Sequence
Target Sequence 
>C. ELEGANS:192032_S_AT
cattcgtggattcccaaccatcaagtatttcgctccaggatctgatgtttctgacgctca
agactacgatggaggacgtcaatcttctgacatcgttgcctgggcttcagctcgtgctca
agaaaacatgccagctccagaggtctttgaaggaatcaaccaacaagtcgtagaggatgc
atgcaaggagaaacagctttgcatttttgccttcctcccacacattcttgactgccaatc
ggagtgcagaaacaattatttggctatgctcaaggagcaatccgagaaattcaagaagaa
cctttggggatggatttgggttgaaggagccgctcagccagctcttgaggagtccttcga
agttggaggttttggatatccagccatgactgctttgaacttccgcaagaacaagtacgc
cgtgctcaagggatccttcggaaaagatggaatccacgagttcctccgtgatctctcgta
tggaaagggacgcacttcttcccttcgaggagatgga

BLASTn GenBank NR
Probe Info
Probe Sequence(5'-3') Probe X Probe Y Probe Interrogation
Position 		Strandedness
CATTCGTGGATTCCCAACCATCAAG 599 215 711 Antisense
AACCATCAAGTATTTCGCTCCAGGA 557 147 726 Antisense
GGATCTGATGTTTCTGACGCTCAAG 134 513 748 Antisense
GTCAATCTTCTGACATCGTTGCCTG 681 463 788 Antisense
AAACATGCCAGCTCCAGAGGTCTTT 585 127 834 Antisense
AACAGCTTTGCATTTTTGCCTTCCT 381 135 902 Antisense
CACACATTCTTGACTGCCAATCGGA 423 195 929 Antisense
CTCAGCCAGCTCTTGAGGAGTCCTT 551 227 1043 Antisense
GCCATGACTGCTTTGAACTTCCGCA 630 279 1093 Antisense
AGATGGAATCCACGAGTTCCTCCGT 671 65 1155 Antisense
CACTTCTTCCCTTCGAGGAGATGGA 196 197 1203 Antisense
Sequence Source Affymetrix Proprietary Database