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[192006_s_at]

Description E01H11.1 /REP_DB=WormBase Gene ID /WP=CE02586 /GEN=kin-11 /TR=Q19025 /GB=AAA68710.1 /SUBMIT=ST.LOUIS /CHR=X /FEA=Sanger Annotation /DEF=Protein kinase C
Cluster 6grp_highest_10_10 > 99      6grp_high1_10_10 > 99      4grp_highest_8_8 > 19      4grp_high_8_8 > 63      6grp_highest_nonorm > 91      6grp_total > 95      4grp_total > 56      6grp_cgc > 78      6grp_cgc_sub > In      6grp_total_sub > Increase      4grp_rule_based > L3      

Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 216
1 2 3 4 range
A 270.3
(1.8)
P
204.3
(-3)
P
286.2
(3)
P
212
(-2.4)
P
82
B 175.4
(-3)
P
263.3
(-0.1)
P
357.6
(3)
P
207.4
(-1.9)
P
182
C 142.1
(-3)
P
216.6
(-0.5)
P
323.5
(3)
P
147.2
(-2.8)
P
181
avr 195.9
(-2.7)
228.1
(-1.2)
322.4
(3)
188.9
(-3)
134

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 223
1 2 3 4 5 6 range
A 226.4
(-1.2)
P
172.1
(-3)
P
250
(-0.5)
P
214.3
(-1.6)
P
357.4
(3)
P
312.2
(1.5)
P
185
B 134.5
(-3)
P
143.6
(-2.7)
P
196.9
(-0.8)
P
207.8
(-0.4)
P
242.9
(0.9)
P
302.5
(3)
P
168
C 227.7
(1)
P
191.5
(-0.6)
P
138.9
(-3)
P
243.5
(1.8)
P
270.9
(3)
P
208.8
(0.2)
P
132
avr 196.2
(-1.7)
169.1
(-3)
195.3
(-1.7)
221.9
(-0.4)
290.4
(3)
274.5
(2.2)
121
No Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 88
1 2 3 4 range
A 98.4
(3)
P
44.3
(-1.8)
P
74.8
(0.9)
P
31
(-3)
P
67
B 55.9
(-1.2)
P
65
(0.2)
P
82.9
(3)
P
44.2
(-3)
P
39
C 47
(-1.5)
P
62.3
(-0.4)
P
112.8
(3)
P
24.8
(-3)
P
88
avr 67.1
(0.6)
57.2
(-0.5)
90.2
(3)
33.3
(-3)
57

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 78
1 2 3 4 5 6 range
A 41.7
(-3)
P
61.2
(-1.2)
P
54.4
(-1.8)
P
54.4
(-1.8)
P
107.8
(3)
P
76
(0.1)
P
66
B 46.8
(-3)
P
47.8
(-2.9)
P
47.8
(-2.9)
P
55
(-2.3)
P
98.7
(1.7)
P
112.8
(3)
P
66
C 84.4
(2.6)
P
58.4
(-0.4)
P
35.3
(-3)
P
49
(-1.4)
P
87.7
(3)
P
69.9
(1)
P
52
avr 57.6
(-1.6)
55.8
(-1.9)
45.8
(-3)
52.8
(-2.2)
98.1
(3)
86.2
(1.6)
52
NetAffx Links Cluster Members
Consensus/Exemplar
Group Members
GeneChip Array Information
Probe Set ID 192006_s_at
GeneChip Array C. elegans Genome Array
Organism Common Name Nematode
Probe Design Information
Transcript ID(Array Design) affy.Ce.16119
Sequence Type Exemplar sequence
Representative Public ID E01H11.1 NCBI
Target Description E01H11.1 /REP_DB=WormBase Gene ID /WP=CE02586 /GEN=kin-11 /TR=Q19025 /GB=AAA68710.1 /SUBMIT=ST.LOUIS /CHR=X /FEA=Sanger Annotation /DEF=Protein kinase C
Cluster Evidence This cluster is supported by a Sanger Annotation.
Annotation Method Description
Annotation Description This probe set was annotated using the Matching Probes based pipeline to a RefSeq identifier using 1 transcript(s).
Annotation Grade This is a grade A annotation.
Annotation Transcript Cluster (# of Matching Probes) NM_001029346(11), NM_001029347(11)
Transcript Assignments
Representative
Transcript
Description Matching Probes Related Probesets by Grade
NM_001029346 NCBI Caenorhabditis elegans Protein Kinase C family member (pkc-2) (pkc-2) mRNA, complete cds. 11/11 None
NM_001029347 NCBI Caenorhabditis elegans Protein Kinase C family member (pkc-2) (pkc-2) mRNA, complete cds. 11/11 None
GENEFINDER00000040113 ENSEMBL cdna:GeneFinder chromosome:CEL140:X:9376488:9383554:1 11/11 None
SNAP00000040111 ENSEMBL cdna:SNAP chromosome:CEL140:X:9379963:9383554:1 11/11 None
E01H11.1b ENSEMBL cdna:known chromosome:CEL140:X:9371060:9383841:1 gene:E01H11.1 11/11 A 
E01H11.1c ENSEMBL cdna:known chromosome:CEL140:X:9376201:9385656:1 gene:E01H11.1 11/11 A 
Annotation Notes
There are no noteworthy cross hybridizing mRNAs found for this probe set.
Splice Variants
Entrez Total Refseq Isoforms Total Detected By This Probeset Refseq Probesets
181166 3 2 NM_001029345 175780_at (11), 175781_s_at (11)
NM_001029346 175779_at (11), 192006_s_at (11)
NM_001029347 175781_s_at (11), 186204_at (11), 192005_at (11), 192006_s_at (11)
Genomic Alignment of Consensus/Exemplar Sequence
Assembly Wormbase March 2004
Alignment(s)
Position Identity Coverage Cytoband
chrX:9378798-9385656(+) 100.0 100.0
Public Domain and Genome References
Ensembl E01H11.1
Functional Annotations
Protein Similarities
Method ID Description E-Value
blast AAM51504 Protein kinase c protein 2, isoform b [Caenorhabditis elegans] ref|NP_001024517.1| Protein Kinase C family member (pkc-2) [Caenorhabditis elegans] sp|P90980|KPC2_CAEEL Protein kinase C-like 2 (PKC2) 0.0
blast AAB40869 protein kinase C2 B isoform [Caenorhabditis elegans] 0.0
blast T15903 protein kinase C homolog - Caenorhabditis elegans 0.0
blast AAA68709 Protein kinase c protein 2, isoform c [Caenorhabditis elegans] ref|NP_001024518.1| Protein Kinase C family member (pkc-2) [Caenorhabditis elegans] 0.0
blast CAE69829 Hypothetical protein CBG16150 [Caenorhabditis briggsae] 0.0
Protein Families
Method ID Description E-Value
ec A2S7_HUMAN (Q96Q40) Serine/threonine-protein kinase ALS2CR7 (EC 2.7.1.37) (Amyotrophic lateral sclerosis 2 chromosomal region candidate gene protein 7) 1.0E-65
ec A2S7_HUMAN (Q96Q40) Serine/threonine-protein kinase ALS2CR7 (EC 2.7.1.37) (Amyotrophic lateral sclerosis 2 chromosomal region candidate gene protein 7) 2.0E-68
hanks 1.2.3 AGC group; AGC I Diacylglycerol-activated/phospholipid-dependent protein kinase C (PKC) family; DPKC53b 1.0E-122
hanks 1.2.3 AGC group; AGC I Diacylglycerol-activated/phospholipid-dependent protein kinase C (PKC) family; DPKC53b 1.0E-125
hanks 1.2.3 AGC group; AGC I Diacylglycerol-activated/phospholipid-dependent protein kinase C (PKC) family; DPKC53b 1.0E-126
Protein Domains
Database ID Description E-Value
Pfam IPR000008 EMBL-EBI C2 domain 1.6E-37
Pfam IPR002219 EMBL-EBI Protein kinase C, phorbol ester/diacylglycerol binding 2.0E-24
Pfam IPR002219 EMBL-EBI Protein kinase C, phorbol ester/diacylglycerol binding 6.2E-24
Pfam IPR000719 EMBL-EBI Protein kinase 3.0E-81
Pfam IPR000961 EMBL-EBI Protein kinase C-terminal domain 2.7E-21
Pfam IPR000008 EMBL-EBI C2 domain 1.6E-37
Pfam IPR002219 EMBL-EBI Protein kinase C, phorbol ester/diacylglycerol binding 2.0E-24
Pfam IPR002219 EMBL-EBI Protein kinase C, phorbol ester/diacylglycerol binding 6.2E-24
Pfam IPR000719 EMBL-EBI Protein kinase 3.0E-81
Pfam IPR000961 EMBL-EBI Protein kinase C-terminal domain 2.7E-21
Pfam IPR000961 EMBL-EBI Protein kinase C-terminal domain 7.5E-21
Pfam IPR000008 EMBL-EBI C2 domain 1.6E-37
Pfam IPR002219 EMBL-EBI Protein kinase C, phorbol ester/diacylglycerol binding 2.0E-24
Pfam IPR002219 EMBL-EBI Protein kinase C, phorbol ester/diacylglycerol binding 6.2E-24
Pfam IPR000719 EMBL-EBI Protein kinase 3.6E-79
Pfam IPR000961 EMBL-EBI Protein kinase C-terminal domain 2.7E-21
Pfam IPR000008 EMBL-EBI C2 domain 1.6E-37
Pfam IPR002219 EMBL-EBI Protein kinase C, phorbol ester/diacylglycerol binding 2.0E-24
Pfam IPR002219 EMBL-EBI Protein kinase C, phorbol ester/diacylglycerol binding 6.2E-24
Pfam IPR000719 EMBL-EBI Protein kinase 3.0E-81
Pfam IPR000961 EMBL-EBI Protein kinase C-terminal domain 2.7E-21
Trans Membrane
ID Number Of Domains Domain Boundaries
NP_001024518.1 3 588-610,824-843,848-870
E01H11.1c 3 588-610,824-843,848-870
Sequence
Target Sequence
>C. ELEGANS:192006_S_AT
agccaaaactgaagaccgataggtcaacggaaaactttgaccattcgttcctcaaattgc
ccaccaaaatgacaccgccggattgggaagttttggaaaatctcaagggcgacgagttca
gcaacttttcatttgtcaacccgttttatgtcaaagatg


BLASTn GenBank NR
Probe Info
Probe Sequence(5'-3') Probe X Probe Y Probe Interrogation
Position
Strandedness
AGCCAAAACTGAAGACCGATAGGTC 459 81 2087 Antisense
GAAAACTTTGACCATTCGTTCCTCA 697 353 2116 Antisense
TTGACCATTCGTTCCTCAAATTGCC 162 703 2123 Antisense
AAATTGCCCACCAAAATGACACCGC 505 113 2140 Antisense
ACCAAAATGACACCGCCGGATTGGG 318 83 2149 Antisense
GACACCGCCGGATTGGGAAGTTTTG 303 351 2157 Antisense
TGGAAAATCTCAAGGGCGACGAGTT 281 531 2180 Antisense
GGGCGACGAGTTCAGCAACTTTTCA 647 489 2193 Antisense
GTTCAGCAACTTTTCATTTGTCAAC 172 445 2202 Antisense
TTCATTTGTCAACCCGTTTTATGTC 257 689 2214 Antisense
GTCAACCCGTTTTATGTCAAAGATG 545 461 2221 Antisense
Sequence Source Affymetrix Proprietary Database