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[192003_s_at] mitochondrial 2-oxoglutartae

Description K11G12.5 /REP_DB=WormBase Gene ID /WP=CE02827 /TR=Q27322 /GB=AAC46570.1 /SUBMIT=ST.LOUIS /CHR=X /FEA=Sanger Annotation /DEF=mitochondrial 2-oxoglutartae
Cluster 6grp_highest_10_10 > 34      6grp_high1_10_10 > 32      4grp_highest_8_8 > 33      4grp_high_8_8 > 50      6grp_highest_nonorm > 24      6grp_total > 31      4grp_total > 61      6grp_highest_sub > 02_03      6grp_high1_sub > 02_03      6grp_total_sub > Hat      6grp_rule_based > S3      4grp_rule_based > L1      

Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 3608
1 2 3 4 range
A 4010.9
(3)
P 		3291.9
(1.8)
P 		2890.7
(1.1)
P 		402.9
(-3)
P 		3608
B 3949.8
(3)
P 		2908.7
(1.2)
P 		3034.9
(1.4)
P 		426.4
(-3)
P 		3523
C 3377.5
(3)
P 		2962.1
(2.1)
P 		2854
(1.9)
P 		511.2
(-3)
P 		2866
avr 3779.4
(3) 		3054.2
(1.7) 		2926.5
(1.5) 		446.8
(-3) 		3333

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 2120
1 2 3 4 5 6 range
A 2612
(0.4)
P 		3405.7
(3)
P 		3118.9
(2.1)
P 		2670.2
(0.6)
P 		2041.4
(-1.4)
P 		1565.6
(-3)
P 		1840
B 2525.7
(0.2)
P 		3220.6
(2.7)
P 		3301.8
(3)
P 		2812.8
(1.3)
P 		2121
(-1.2)
P 		1610.9
(-3)
P 		1691
C 2557.3
(-0.5)
P 		3078.3
(1.1)
P 		3685.7
(3)
P 		3131.4
(1.3)
P 		2146.6
(-1.8)
P 		1774.3
(-3)
P 		1911
avr 2565
(0.2) 		3234.9
(2.5) 		3368.8
(3) 		2871.5
(1.3) 		2103
(-1.4) 		1650.3
(-3) 		1719
No Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 1401
1 2 3 4 range
A 1460.4
(3)
P 		714.6
(-0.2)
P 		755.7
(-0)
P 		59
(-3)
P 		1401
B 1259.6
(3)
P 		718.4
(0.2)
P 		703.3
(0.1)
P 		90.9
(-3)
P 		1169
C 1118
(3)
P 		851.6
(1.5)
P 		994.7
(2.3)
P 		86.2
(-3)
P 		1032
avr 1279.3
(3) 		761.5
(0.4) 		817.9
(0.7) 		78.7
(-3) 		1201

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 830
1 2 3 4 5 6 range
A 481.5
(-2.3)
P 		1211.2
(3)
P 		679.2
(-0.8)
P 		677.2
(-0.9)
P 		616
(-1.3)
P 		381.2
(-3)
P 		830
B 878.8
(0.5)
P 		1072
(3)
P 		801.8
(-0.4)
P 		745
(-1.2)
P 		861.7
(0.3)
P 		600.7
(-3)
P 		471
C 947.9
(3)
P 		939.3
(2.9)
P 		938.1
(2.8)
P 		629.7
(-2.4)
P 		694.6
(-1.3)
P 		594
(-3)
P 		354
avr 769.4
(-0.3) 		1074.2
(3) 		806.4
(0.1) 		684
(-1.3) 		724.1
(-0.8) 		525.3
(-3) 		549
NetAffx Links Cluster Members
Consensus/Exemplar
Group Members
GeneChip Array Information
Probe Set ID 192003_s_at
GeneChip Array C. elegans Genome Array
Organism Common Name Nematode
Probe Design Information
Transcript ID(Array Design) affy.Ce.17237
Sequence Type Exemplar sequence
Representative Public ID K11G12.5 NCBI
Target Description K11G12.5 /REP_DB=WormBase Gene ID /WP=CE02827 /TR=Q27322 /GB=AAC46570.1 /SUBMIT=ST.LOUIS /CHR=X /FEA=Sanger Annotation /DEF=mitochondrial 2-oxoglutartae
Cluster Evidence This cluster is supported by a Sanger Annotation.
Annotation Method Description
Annotation Description This probe set was annotated using the Matching Probes based pipeline to a RefSeq,GenBank identifier using 1 transcript(s).
Annotation Grade This is a grade A annotation.
Annotation Transcript Cluster (# of Matching Probes) NM_076732(11), X76114(11)
Transcript Assignments
Representative
Transcript		 Description Matching Probes Related Probesets by Grade
NM_076732 NCBI Caenorhabditis elegans K11G12.5 (K11G12.5) mRNA, complete cds. 11/11 None
X76114 NCBI C.elegans mRNA for Oxoglutarate/malate carrier protein. 11/11 None
SNAP00000013742 ENSEMBL cdna:SNAP chromosome:CEL140:X:6723945:6729610:-1 11/11 None
GENEFINDER00000013744 ENSEMBL cdna:GeneFinder chromosome:CEL140:X:6723945:6729610:-1 11/11 None
K11G12.5 ENSEMBL cdna:known chromosome:CEL140:X:6723453:6725621:-1 gene:K11G12.5 11/11 None
Annotation Notes
There are no noteworthy cross hybridizing mRNAs found for this probe set.
Genomic Alignment of Consensus/Exemplar Sequence
Assembly Wormbase March 2004
Alignment(s)
Position Identity Coverage Cytoband
chrX:6723944-6725613(-) 100.0 100.0
Public Domain and Genome References
Gene Title mitochondrial 2-oxoglutartae
Ensembl K11G12.5
Entrez Gene 180940 Entrez gene
SwissProt Q27322 EMBL-EBI
WormBase CE02827 Wormbase
Functional Annotations
Ortholog
ID Title Organism
ATH1-121501:245882_AT mitochondrial substrate carrier family protein at
DROSOPHILA_2:1635808_S_AT dm
DROSGENOME1:151853_AT dm
HU35KSUBC:RC_AA285019_AT solute carrier family 25 (mitochondrial carrier; dicarboxylate transporter), member 10 hs
HG-U133A:218275_AT solute carrier family 25 (mitochondrial carrier; dicarboxylate transporter), member 10 hs
HG-U133_PLUS_2:218275_AT solute carrier family 25 (mitochondrial carrier; dicarboxylate transporter), member 10 hs
HG-FOCUS:218275_AT solute carrier family 25 (mitochondrial carrier; dicarboxylate transporter), member 10 hs
HG-U133A_2:218275_AT solute carrier family 25 (mitochondrial carrier; dicarboxylate transporter), member 10 hs
U133_X3P:G6912333_3P_AT solute carrier family 25 (mitochondrial carrier; dicarboxylate transporter), member 10 hs
HG-U95C:64446_AT solute carrier family 25 (mitochondrial carrier; dicarboxylate transporter), member 10 hs
HG-U95D:74242_AT Solute carrier family 25 (mitochondrial carrier; dicarboxylate transporter), member 10 hs
HG-U95D:74244_R_AT Solute carrier family 25 (mitochondrial carrier; dicarboxylate transporter), member 10 hs
MG-U74BV2:108883_AT solute carrier family 25 (mitochondrial carrier, dicarboxylate transporter), member 10 mm
MU11KSUBA:AA213312_S_AT solute carrier family 25 (mitochondrial carrier, dicarboxylate transporter), member 10 mm
MG-U74AV2:99112_AT solute carrier family 25 (mitochondrial carrier, dicarboxylate transporter), member 10 mm
MOE430A:1416954_AT solute carrier family 25 (mitochondrial carrier, dicarboxylate transporter), member 10 mm
MOUSE430A_2:1416954_AT solute carrier family 25 (mitochondrial carrier, dicarboxylate transporter), member 10 mm
MOUSE430_2:1416954_AT solute carrier family 25 (mitochondrial carrier, dicarboxylate transporter), member 10 mm
MOE430A:1416955_AT solute carrier family 25 (mitochondrial carrier, dicarboxylate transporter), member 10 mm
MOUSE430A_2:1416955_AT solute carrier family 25 (mitochondrial carrier, dicarboxylate transporter), member 10 mm
MOUSE430_2:1416955_AT solute carrier family 25 (mitochondrial carrier, dicarboxylate transporter), member 10 mm
MU19KSUBA:TC16194_I_AT Solute carrier family 25 (mitochondrial carrier, dicarboxylate transporter), member 10, mRNA (cDNA clone MGC:7207 IMAGE:3482316) mm
RG-U34A:RC_AA859666_I_AT solute carrier family 25 (mitochondrial carrier; dicarboxylate transporter), member 10 rn
RG-U34A:AJ223355_G_AT solute carrier family 25 (mitochondrial carrier; dicarboxylate transporter), member 10 rn
RG-U34A:AJ223355_AT solute carrier family 25 (mitochondrial carrier; dicarboxylate transporter), member 10 rn
RAE230A:1370020_AT solute carrier family 25 (mitochondrial carrier; dicarboxylate transporter), member 10 rn
RAT230_2:1370020_AT solute carrier family 25 (mitochondrial carrier; dicarboxylate transporter), member 10 rn
YEAST_2:1774282_AT Mitochondrial dicarboxylate carrier, integral membrane protein, catalyzes a dicarboxylate-phosphate exchange across the inner mitochondrial membrane, transports cytoplasmic dicarboxylates into the mitochondrial matrix Sc
Gene Ontology
GO Biological Process (view graph)
ID Description Evidence Links
6810 transport inferred from electronic annotation QuickGO AmiGO
GO Cellular Component (view graph)
ID Description Evidence Links
5743 mitochondrial inner membrane inferred from electronic annotation QuickGO AmiGO
16020 membrane inferred from electronic annotation QuickGO AmiGO
GO Molecular Function (view graph)
ID Description Evidence Links
5488 binding inferred from electronic annotation QuickGO AmiGO
Protein Similarities
Method ID Description E-Value
blast AAC46571 Hypothetical protein K11G12.6 [Caenorhabditis elegans] ref|NP_509134.2| K11G12.6 [Caenorhabditis elegans] 0.0
blast CAE65782 Hypothetical protein CBG10877 [Caenorhabditis briggsae] 0.0
blast AAC46570 Hypothetical protein K11G12.5 [Caenorhabditis elegans] ref|NP_509133.1| K11G12.5 [Caenorhabditis elegans] emb|CAA53720.1| Oxoglutarate/malate carrier protein [Caenorhabditis elegans] 1.0E-151
blast CAE65781 Hypothetical protein CBG10876 [Caenorhabditis briggsae] 1.0E-144
Protein Domains
Database ID Description E-Value
Pfam IPR001993 EMBL-EBI Mitochondrial substrate carrier 1.9E-27
Pfam IPR001993 EMBL-EBI Mitochondrial substrate carrier 1.5E-23
Pfam IPR001993 EMBL-EBI Mitochondrial substrate carrier 1.5E-24
Pfam IPR001993 EMBL-EBI Mitochondrial substrate carrier 1.7E-14
Pfam IPR001993 EMBL-EBI Mitochondrial substrate carrier 1.5E-23
Pfam IPR001993 EMBL-EBI Mitochondrial substrate carrier 1.5E-24
Pfam IPR009613 EMBL-EBI Protein of unknown function DUF1222 2.5E-42
Pfam IPR001993 EMBL-EBI Mitochondrial substrate carrier 1.7E-14
Pfam IPR001993 EMBL-EBI Mitochondrial substrate carrier 1.5E-23
Pfam IPR001993 EMBL-EBI Mitochondrial substrate carrier 1.5E-24
Pfam IPR009613 EMBL-EBI Protein of unknown function DUF1222 2.5E-42
Trans Membrane
ID Number Of Domains Domain Boundaries
SNAP00000013742 9 13-35,78-100,113-135,155-174,226-248,258-280,287-306,337-359,372-394
GENEFINDER00000013744 9 13-35,69-91,104-126,146-165,217-239,249-271,278-297,328-350,363-385
Sequence
Target Sequence 
>C. ELEGANS:192003_S_AT
taccaaaaggcgcttctcgccggttttgctggagcatgcggtggaatggttggaacacct
ggagatttggttaacgttagaatgcagaacgattctaagcttcccctagaacagcgcaga
aactacaaacacgctttggacggattggtgaggattactagagaagagggattcatgaag
atgttcaatggagctactatggcgacatctcgtgctattctcatgaccattggtcagttg
tcattctatgatcaaattaagcagactcttatctcttctggagttgccgaggacaaccta
caaactcactttgccagttcgatcagtgcggctagtgtggctactgtcatgactcaacca
ttggacgtgatgaagaccagaatgatgaacgccgcccctggcgagtttaagggaattctc
gactgcttcatgttcaccgccaagctcggtccaatgggcttctttaagggattcattccg
gcttgggctcgtcttgccccacacaccgttcttacattcatcttttt

BLASTn GenBank NR
Probe Info
Probe Sequence(5'-3') Probe X Probe Y Probe Interrogation
Position 		Strandedness
TACCAAAAGGCGCTTCTCGCCGGTT 632 639 310 Antisense
AGCTACTATGGCGACATCTCGTGCT 454 79 501 Antisense
TCGTGCTATTCTCATGACCATTGGT 435 603 519 Antisense
GACTCTTATCTCTTCTGGAGTTGCC 442 373 573 Antisense
AACTCACTTTGCCAGTTCGATCAGT 168 141 612 Antisense
CGATCAGTGCGGCTAGTGTGGCTAC 308 249 629 Antisense
GTGTGGCTACTGTCATGACTCAACC 592 487 644 Antisense
GAATTCTCGACTGCTTCATGTTCAC 214 325 722 Antisense
GCTCGGTCCAATGGGCTTCTTTAAG 149 299 753 Antisense
TAAGGGATTCATTCCGGCTTGGGCT 408 637 774 Antisense
ACACCGTTCTTACATTCATCTTTTT 355 107 812 Antisense
Sequence Source Affymetrix Proprietary Database