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[191985_at] protein-tyrosine phosphatase

Description F40G12.10 /REP_DB=WormBase Gene ID /WP=CE10194 /TR=Q20252 /GB=CAB01189.1 /SUBMIT=HINXTON /CHR=5 /FEA=Sanger Annotation /DEF=protein-tyrosine phosphatase
Cluster 6grp_total > 98      4grp_total > 07      6grp_total_sub > Increase      6grp_rule_based > S6      

Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 18
1 2 3 4 range
A 10.7
(-1.4)
A 		6.6
(-3)
A 		18.3
(1.6)
A 		21.8
(3)
A 		15
B 21
(3)
A 		12.5
(-0.2)
A 		5
(-3)
A 		9.3
(-1.4)
A 		16
C 16.1
(1.3)
A 		3.5
(-3)
A 		21.2
(3)
A 		10.2
(-0.7)
A 		18
avr 15.9
(3) 		7.5
(-3) 		14.8
(2.2) 		13.8
(1.5) 		8

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 182
1 2 3 4 5 6 range
A 6.8
(-2.9)
A 		4.2
(-2.9)
A 		2.4
(-3)
A 		33
(-2)
A 		122.5
(1)
P 		184
(3)
P 		182
B 3.5
(-3)
A 		5.9
(-2.9)
A 		2.9
(-3)
A 		9.1
(-2.7)
A 		112
(1.5)
P 		148.9
(3)
P 		146
C 11
(-2.9)
A 		21.2
(-2.4)
A 		22.3
(-2.3)
A 		9.1
(-3)
A 		94.2
(1.4)
P 		124.4
(3)
P 		115
avr 7.1
(-3) 		10.4
(-2.9) 		9.2
(-2.9) 		17.1
(-2.6) 		109.6
(1.2) 		152.4
(3) 		145
No Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 6
1 2 3 4 range
A 3.9
(1.4)
A 		1.4
(-3)
A 		4.8
(3)
A 		3.2
(0.2)
A 		3
B 6.7
(3)
A 		3.1
(-0.9)
A 		1.2
(-3)
A 		2
(-2.1)
A 		6
C 5.3
(1)
A 		1
(-3)
A 		7.4
(3)
A 		1.7
(-2.3)
A 		6
avr 5.3
(3) 		1.8
(-3) 		4.5
(1.6) 		2.3
(-2.1) 		4

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 55
1 2 3 4 5 6 range
A 1.3
(-2.9)
A 		1.5
(-2.9)
A 		0.5
(-3)
A 		8.4
(-1.9)
A 		37
(1.9)
P 		44.8
(3)
P 		44
B 1.2
(-2.9)
A 		2
(-2.9)
A 		0.7
(-3)
A 		2.4
(-2.8)
A 		45.5
(1.9)
P 		55.5
(3)
P 		55
C 4.1
(-2.7)
A 		6.5
(-2.3)
A 		5.7
(-2.4)
A 		1.8
(-3)
A 		30.5
(1.3)
P 		41.7
(3)
P 		40
avr 2.2
(-3) 		3.3
(-2.9) 		2.3
(-3) 		4.2
(-2.7) 		37.7
(1.7) 		47.3
(3) 		45
NetAffx Links Cluster Members
Consensus/Exemplar
GeneChip Array Information
Probe Set ID 191985_at
GeneChip Array C. elegans Genome Array
Organism Common Name Nematode
Probe Design Information
Transcript ID(Array Design) affy.Ce.14127
Sequence Type Exemplar sequence
Representative Public ID F40G12.10 NCBI
Target Description F40G12.10 /REP_DB=WormBase Gene ID /WP=CE10194 /TR=Q20252 /GB=CAB01189.1 /SUBMIT=HINXTON /CHR=5 /FEA=Sanger Annotation /DEF=protein-tyrosine phosphatase
Cluster Evidence This cluster is supported by a Sanger Annotation.
Annotation Method Description
Annotation Description This probe set was annotated using the Matching Probes based pipeline to a RefSeq identifier using 1 transcript(s).
Annotation Grade This is a grade A annotation.
Annotation Transcript Cluster (# of Matching Probes) NM_074136(11)
Transcript Assignments
Representative
Transcript		 Description Matching Probes Related Probesets by Grade
NM_074136 NCBI Caenorhabditis elegans F40G12.10 (F40G12.10) mRNA, complete cds. 11/11 None
SNAP00000026736 ENSEMBL cdna:SNAP chromosome:CEL140:V:14286157:14287875:1 11/11 None
GENEFINDER00000026760 ENSEMBL cdna:GeneFinder chromosome:CEL140:V:14286343:14289922:1 11/11 None
F40G12.10 ENSEMBL cdna:known chromosome:CEL140:V:14286157:14287875:1 gene:F40G12.10 11/11 None
Annotation Notes
There are no noteworthy cross hybridizing mRNAs found for this probe set.
Genomic Alignment of Consensus/Exemplar Sequence
Assembly Wormbase March 2004
Alignment(s)
Position Identity Coverage Cytoband
chrV:14286156-14287875(+) 100.0 100.0
Public Domain and Genome References
Gene Title protein-tyrosine phosphatase
Ensembl F40G12.10
Entrez Gene 179927 Entrez gene
SwissProt Q20252 EMBL-EBI
WormBase CE10194 Wormbase
Functional Annotations
Gene Ontology
GO Biological Process (view graph)
ID Description Evidence Links
6470 protein amino acid dephosphorylation inferred from electronic annotation QuickGO AmiGO
GO Molecular Function (view graph)
ID Description Evidence Links
4725 protein tyrosine phosphatase activity inferred from electronic annotation QuickGO AmiGO
Protein Similarities
Method ID Description E-Value
blast CAB01189 Hypothetical protein F40G12.10 [Caenorhabditis elegans] ref|NP_506537.1| F40G12.10 [Caenorhabditis elegans] 0.0
blast T15305 hypothetical protein B0280.11 - Caenorhabditis elegans 1.0E-156
blast T15305 hypothetical protein B0280.11 - Caenorhabditis elegans 1.0E-155
blast AAA19089 Hypothetical protein B0280.11 [Caenorhabditis elegans] ref|NP_498560.1| B0280.11 [Caenorhabditis elegans] sp|P42083|YKCA_CAEEL Hypothetical protein B0280.11 in chromosome III 1.0E-145
Protein Domains
Database ID Description E-Value
Pfam IPR000242 EMBL-EBI Tyrosine specific protein phosphatase 4.1E-30
Pfam IPR000242 EMBL-EBI Tyrosine specific protein phosphatase 4.1E-30
Sequence
Target Sequence 
>C. ELEGANS:191985_AT
caaagactcttcattcttcttggcgaagaagaactcgataaacctactctgagcgagtac
tttccagaagacttcaaagagttcaagacgattcgtgtgaacaatcggaagactgtgccg
aagactgaagagcaagcaaacactcaattgtactatgaagttgtgccaaaggattgtgca
gaagctccatttgcaatgattgagatttgcgatttttggcctgatgcgaagattccaacg
atgggttataacagaattgctgcaactgctgcaagcgtgtttgaatctgatattgattgt
gatgcttcttgtgctattgtgagcaattacggagccggtagagcaggatcattttttgtg
gcagttttggctattgagaagttgcaggcaggagaagccccaaatatcaaagaaatcgct
ctctcagttcgctcgcaacgtcctgctgctatcgaaacattgtctcaatacatgttcact
tatgtgattgctctgacttatggactgaagcatgtcaaggatccggctctg

BLASTn GenBank NR
Probe Info
Probe Sequence(5'-3') Probe X Probe Y Probe Interrogation
Position 		Strandedness
CAAAGACTCTTCATTCTTCTTGGCG 182 193 709 Antisense
GAACTCGATAAACCTACTCTGAGCG 594 349 739 Antisense
GAGCGAGTACTTTCCAGAAGACTTC 282 385 759 Antisense
GATTTGCGATTTTTGGCCTGATGCG 618 427 912 Antisense
GAATTGCTGCAACTGCTGCAAGCGT 233 323 962 Antisense
GATTGTGATGCTTCTTGTGCTATTG 544 435 1003 Antisense
ACGGAGCCGGTAGAGCAGGATCATT 599 91 1037 Antisense
CAAAGAAATCGCTCTCTCAGTTCGC 77 193 1116 Antisense
CAACGTCCTGCTGCTATCGAAACAT 391 187 1144 Antisense
GTGATTGCTCTGACTTATGGACTGA 556 483 1192 Antisense
GAAGCATGTCAAGGATCCGGCTCTG 468 341 1215 Antisense
Sequence Source Affymetrix Proprietary Database