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[191984_at] protein-tyrosine phosphatase

Description R06B10.1 /REP_DB=WormBase Gene ID /WP=CE17200 /TR=O44875 /GB=AAK21448.1 /SUBMIT=ST.LOUIS /CHR=3 /FEA=Sanger Annotation /DEF=protein-tyrosine phosphatase
Cluster 6grp_total > 69      4grp_total > 10      6grp_total_sub > Cup      

Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 73
1 2 3 4 range
A 45.7
(-1.1)
A 		28.3
(-3)
A 		47.6
(-0.9)
A 		83.1
(3)
M 		55
B 38.2
(0.7)
A 		54.5
(3)
A 		11.7
(-3)
A 		47.4
(2)
A 		43
C 10.1
(-3)
A 		21
(-1.8)
A 		34.6
(-0.4)
A 		66.8
(3)
A 		57
avr 31.3
(-3) 		34.6
(-2.4) 		31.3
(-3) 		65.8
(3) 		35

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 71
1 2 3 4 5 6 range
A 48.8
(1)
A 		2
(-3)
A 		11
(-2.2)
A 		41.7
(0.4)
A 		29.7
(-0.6)
A 		72.6
(3)
A 		71
B 32.3
(-0.7)
A 		39
(0)
A 		9.6
(-3)
A 		19.7
(-2)
A 		34.5
(-0.5)
A 		68.3
(3)
P 		59
C 27.2
(-1.2)
A 		71.6
(3)
M 		7.8
(-3)
A 		36.9
(-0.3)
A 		48.6
(0.8)
A 		38.1
(-0.2)
A 		64
avr 36.1
(0.2) 		37.5
(0.3) 		9.5
(-3) 		32.8
(-0.2) 		37.6
(0.4) 		59.7
(3) 		50
No Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 14
1 2 3 4 range
A 16.6
(3)
A 		6.1
(-3)
A 		12.4
(0.6)
A 		12.2
(0.5)
M 		11
B 12.2
(2.3)
A 		13.5
(3)
A 		2.7
(-3)
A 		10.1
(1.1)
A 		11
C 3.4
(-3)
A 		6
(-1.2)
A 		12.1
(3)
A 		11.3
(2.4)
A 		9
avr 10.7
(1.9) 		8.5
(-3) 		9.1
(-1.7) 		11.2
(3) 		3

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 25
1 2 3 4 5 6 range
A 9
(-0.1)
A 		0.7
(-3)
A 		2.4
(-2.4)
A 		10.6
(0.5)
A 		9
(-0.1)
A 		17.7
(3)
A 		17
B 11.2
(-0.7)
A 		13
(-0.2)
A 		2.3
(-3)
A 		5.2
(-2.3)
A 		14
(0)
A 		25.5
(3)
P 		23
C 10.1
(-0.5)
A 		21.8
(3)
M 		2
(-3)
A 		7.4
(-1.4)
A 		15.7
(1.2)
A 		12.7
(0.2)
A 		20
avr 10.1
(-0.1) 		11.8
(0.5) 		2.2
(-3) 		7.7
(-1) 		12.9
(0.9) 		18.6
(3) 		16
NetAffx Links Cluster Members
Consensus/Exemplar
GeneChip Array Information
Probe Set ID 191984_at
GeneChip Array C. elegans Genome Array
Organism Common Name Nematode
Probe Design Information
Transcript ID(Array Design) affy.Ce.8292
Sequence Type Exemplar sequence
Representative Public ID R06B10.1 NCBI
Target Description R06B10.1 /REP_DB=WormBase Gene ID /WP=CE17200 /TR=O44875 /GB=AAK21448.1 /SUBMIT=ST.LOUIS /CHR=3 /FEA=Sanger Annotation /DEF=protein-tyrosine phosphatase
Cluster Evidence This cluster is supported by a Sanger Annotation.
Annotation Method Description
Annotation Description This probe set was annotated using the Matching Probes based pipeline to a RefSeq identifier using 1 transcript(s).
Annotation Grade This is a grade A annotation.
Annotation Transcript Cluster (# of Matching Probes) NM_064907(11)
Transcript Assignments
Representative
Transcript		 Description Matching Probes Related Probesets by Grade
NM_064907 NCBI Caenorhabditis elegans R06B10.1 (R06B10.1) mRNA, complete cds. 11/11 None
GENEFINDER00000022075 ENSEMBL cdna:GeneFinder chromosome:CEL140:III:966641:974487:-1 11/11 None
SNAP00000022056 ENSEMBL cdna:SNAP chromosome:CEL140:III:966663:971057:-1 11/11 None
R06B10.1 ENSEMBL cdna:known chromosome:CEL140:III:966641:972012:-1 gene:R06B10.1 11/11 None
Annotation Notes
There are no noteworthy cross hybridizing mRNAs found for this probe set.
Genomic Alignment of Consensus/Exemplar Sequence
Assembly Wormbase March 2004
Alignment(s)
Position Identity Coverage Cytoband
chrIII:966640-972012(-) 100.0 100.0
Public Domain and Genome References
Gene Title protein-tyrosine phosphatase
Ensembl R06B10.1
Entrez Gene 187637 Entrez gene
SwissProt O44875 EMBL-EBI
WormBase CE17200 Wormbase
Functional Annotations
Gene Ontology
GO Biological Process (view graph)
ID Description Evidence Links
6470 protein amino acid dephosphorylation inferred from electronic annotation QuickGO AmiGO
GO Molecular Function (view graph)
ID Description Evidence Links
4721 phosphoprotein phosphatase activity inferred from electronic annotation QuickGO AmiGO
4725 protein tyrosine phosphatase activity inferred from electronic annotation QuickGO AmiGO
Protein Similarities
Method ID Description E-Value
blast AAK21448 Hypothetical protein R06B10.1 [Caenorhabditis elegans] ref|NP_497308.1| R06B10.1 [Caenorhabditis elegans] 0.0
blast AAK29876 Hypothetical protein Y22D7AR.12 [Caenorhabditis elegans] ref|NP_497451.1| Y22D7AR.12 [Caenorhabditis elegans] 0.0
blast AAK29876 Hypothetical protein Y22D7AR.12 [Caenorhabditis elegans] ref|NP_497451.1| Y22D7AR.12 [Caenorhabditis elegans] 1.0E-163
blast AAB54270 Hypothetical protein R155.4 [Caenorhabditis elegans] ref|NP_497486.2| R155.4 [Caenorhabditis elegans] 1.0E-107
blast AAB54270 Hypothetical protein R155.4 [Caenorhabditis elegans] ref|NP_497486.2| R155.4 [Caenorhabditis elegans] 1.0E-105
Protein Domains
Database ID Description E-Value
Pfam IPR003125 EMBL-EBI Protein of unknown function WSN 5.8E-29
Pfam IPR000242 EMBL-EBI Tyrosine specific protein phosphatase 4.7E-57
Pfam IPR003125 EMBL-EBI Protein of unknown function WSN 5.8E-29
Pfam IPR000242 EMBL-EBI Tyrosine specific protein phosphatase 3.4E-34
Pfam IPR000242 EMBL-EBI Tyrosine specific protein phosphatase 8.5E-54
Pfam IPR003125 EMBL-EBI Protein of unknown function WSN 5.8E-29
Pfam IPR000242 EMBL-EBI Tyrosine specific protein phosphatase 4.7E-57
Trans Membrane
ID Number Of Domains Domain Boundaries
NP_497308.1 4 24-43,793-815,1169-1191,1215-1234
R06B10.1 4 24-43,793-815,1169-1191,1215-1234
GENEFINDER00000022075 4 293-312,1082-1104,1478-1500,1524-1543
SNAP00000022056 1 732-754
Sequence
Target Sequence 
>C. ELEGANS:191984_AT
acacgacgccagtcattgttcactgcaaaaatggaatctcaaagtcggcttgttttgcat
atatcgaactcgcgtgccaaatgattcccggactgaccagcgaccaatcggaccgtgaca
ttctttacgttcttttgcgaatgcgtgccgagtgtttcccgaattatcaactatactcgt
tcgcgttgtacggcgtattcatgcgtctaatggaggttggtttttttgaagaagcctcta
agaaaaagccacgtgcagaaaggagtacgactattattgcggcatcttcaatgattggta
ttcggctacaaatactgctcgcgttgaccatatggctagcagagacgggcgccgcatcaa
agagaaaaaacctgagaagtctcttcatgaatttgacgaaaatggaaaaccaaatagatc
cattcttgtctatcctaaacttggcctcg

BLASTn GenBank NR
Probe Info
Probe Sequence(5'-3') Probe X Probe Y Probe Interrogation
Position 		Strandedness
ACACGACGCCAGTCATTGTTCACTG 539 109 3245 Antisense
GTGCCAAATGATTCCCGGACTGACC 700 477 3318 Antisense
GGACCGTGACATTCTTTACGTTCTT 64 523 3354 Antisense
TTCTTTTGCGAATGCGTGCCGAGTG 59 689 3374 Antisense
GCCGAGTGTTTCCCGAATTATCAAC 47 285 3391 Antisense
ACTATACTCGTTCGCGTTGTACGGC 49 103 3414 Antisense
GTTGTACGGCGTATTCATGCGTCTA 130 437 3429 Antisense
GTACGACTATTATTGCGGCATCTTC 372 459 3509 Antisense
CTGCTCGCGTTGACCATATGGCTAG 551 237 3559 Antisense
TATGGCTAGCAGAGACGGGCGCCGC 659 653 3575 Antisense
CTTGTCTATCCTAAACTTGGCCTCG 291 217 3669 Antisense
Sequence Source Affymetrix Proprietary Database