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[191966_at] perinuclear binding protein

Description Y57G11C.22 /REP_DB=WormBase Gene ID /WP=CE14968 /TR=O18246 /GB=CAB16523.1 /SUBMIT=HINXTON /CHR=4 /FEA=Sanger Annotation /DEF=perinuclear binding protein
Cluster 6grp_highest_10_10 > 06      6grp_high1_10_10 > 20      4grp_highest_8_8 > 51      4grp_high_8_8 > 32      6grp_highest_nonorm > 42      6grp_total > 50      4grp_total > 47      6grp_highest_sub > 04      6grp_total_sub > Hat      6grp_rule_based > S4      4grp_rule_based > L1      

Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 328
1 2 3 4 range
A 767.5
(3)
P 		693.2
(0.9)
P 		558.2
(-3)
P 		632.9
(-0.9)
P 		209
B 798.5
(3)
P 		526.3
(-2.4)
P 		503.1
(-2.9)
P 		496.9
(-3)
P 		302
C 735.3
(3)
P 		470.7
(-3)
P 		602.1
(-0)
P 		580.2
(-0.5)
P 		265
avr 767.1
(3) 		563.4
(-2.7) 		554.5
(-3) 		570
(-2.6) 		213

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 665
1 2 3 4 5 6 range
A 1104.6
(3)
P 		770.4
(-1)
P 		830.4
(-0.3)
P 		860.9
(0.1)
P 		635.2
(-2.7)
P 		606.7
(-3)
P 		498
B 659.5
(-2.2)
P 		701.3
(-1.3)
P 		799.3
(1)
P 		887.6
(3)
P 		626.2
(-3)
P 		630.1
(-2.9)
P 		261
C 711.5
(-0.5)
P 		970.8
(1.8)
P 		966.5
(1.8)
P 		1101.8
(3)
P 		439.2
(-3)
P 		663.4
(-1)
P 		663
avr 825.2
(1) 		814.2
(0.9) 		865.4
(1.7) 		950.1
(3) 		566.9
(-3) 		633.4
(-2) 		383
No Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 187
1 2 3 4 range
A 279.4
(3)
P 		150.5
(-1.1)
P 		145.9
(-1.3)
P 		92.7
(-3)
P 		187
B 254.6
(3)
P 		130
(-2)
P 		116.6
(-2.6)
P 		105.9
(-3)
P 		149
C 243.4
(3)
P 		135.3
(-1.5)
P 		209.9
(1.6)
P 		97.8
(-3)
P 		146
avr 259.1
(3) 		138.6
(-1.5) 		157.5
(-0.8) 		98.8
(-3) 		160

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 154
1 2 3 4 5 6 range
A 203.6
(-0.3)
P 		274
(3)
P 		180.9
(-1.4)
P 		218.3
(0.4)
P 		191.7
(-0.9)
P 		147.7
(-3)
P 		126
B 229.5
(0.5)
P 		233.4
(0.9)
P 		194.1
(-3)
P 		235.1
(1.1)
P 		254.4
(3)
P 		235
(1.1)
P 		60
C 263.7
(1.7)
P 		296.2
(3)
P 		246
(1)
P 		221.6
(0.1)
P 		142.1
(-3)
P 		222.1
(0.1)
P 		154
avr 232.3
(0) 		267.9
(3) 		207
(-2.1) 		225
(-0.6) 		196.1
(-3) 		201.6
(-2.5) 		72
NetAffx Links Cluster Members
Consensus/Exemplar
GeneChip Array Information
Probe Set ID 191966_at
GeneChip Array C. elegans Genome Array
Organism Common Name Nematode
Probe Design Information
Transcript ID(Array Design) affy.Ce.8924
Sequence Type Exemplar sequence
Representative Public ID Y57G11C.22 NCBI
Target Description Y57G11C.22 /REP_DB=WormBase Gene ID /WP=CE14968 /TR=O18246 /GB=CAB16523.1 /SUBMIT=HINXTON /CHR=4 /FEA=Sanger Annotation /DEF=perinuclear binding protein
Cluster Evidence This cluster is supported by a Sanger Annotation.
Annotation Method Description
Annotation Description This probe set was annotated using the Matching Probes based pipeline to a RefSeq identifier using 1 transcript(s).
Annotation Grade This is a grade A annotation.
Annotation Transcript Cluster (# of Matching Probes) NM_070395(11)
Transcript Assignments
Representative
Transcript		 Description Matching Probes Related Probesets by Grade
NM_070395 NCBI Caenorhabditis elegans Y57G11C.22 (Y57G11C.22) mRNA, complete cds. 11/11 None
GENEFINDER00000003608 ENSEMBL cdna:GeneFinder chromosome:CEL140:IV:14846410:14853566:1 11/11 None
Y57G11C.22 ENSEMBL cdna:known chromosome:CEL140:IV:14837128:14853589:1 gene:Y57G11C.22 11/11 None
Annotation Notes
Cross Hybridizing mRNA Matched Probes Nature of Assignment Related Probesets by Grade
SNAP00000003497 3/11 Cross Hyb Matching Probes None
SNAP00000003498 7/11 Cross Hyb Matching Probes None
Genomic Alignment of Consensus/Exemplar Sequence
Assembly Wormbase March 2004
Alignment(s)
Position Identity Coverage Cytoband
chrIV:14837803-14853572(+) 99.55 99.55
Public Domain and Genome References
Gene Title perinuclear binding protein
Ensembl Y57G11C.22
Entrez Gene 178409 Entrez gene
SwissProt O18246 EMBL-EBI
WormBase CE14968 Wormbase
Functional Annotations
Ortholog
ID Title Organism
CANINE_2:CFAAFFX.3042.1.S1_AT similar to PRKCA-binding protein (Protein kinase C-alpha binding protein) (Protein interacting with C kinase 1) cfa
DROSOPHILA_2:1623746_A_AT dm
DROSGENOME1:146297_AT dm
CHICKEN:GGA.10043.1.S1_AT similar to protein that interacts with C kinase 1; protein kinase C, alpha binding protein; protein kinase C alpha binding protein gga
HG-U95AV2:35853_AT protein kinase C, alpha binding protein hs
HG-U133A:204746_S_AT protein kinase C, alpha binding protein hs
HG-U133_PLUS_2:204746_S_AT protein kinase C, alpha binding protein hs
HG-FOCUS:204746_S_AT protein kinase C, alpha binding protein hs
HG-U133A_2:204746_S_AT protein kinase C, alpha binding protein hs
U133_X3P:G7110696_3P_A_AT protein kinase C, alpha binding protein hs
MU11KSUBB:Z46720_S_AT protein kinase C, alpha binding protein mm
MG-U74AV2:97684_AT protein kinase C, alpha binding protein mm
MG-U74AV2:161638_F_AT protein kinase C, alpha binding protein mm
MOE430A:1419384_AT protein kinase C, alpha binding protein mm
MOUSE430A_2:1419384_AT protein kinase C, alpha binding protein mm
MOUSE430_2:1419384_AT protein kinase C, alpha binding protein mm
MU19KSUBA:TC21989_S_AT Protein kinase C, alpha binding protein (Prkcabp), mRNA mm
RG-U34C:RC_AI233722_AT protein kinase C, alpha binding protein rn
RAE230A:1368169_AT protein kinase C, alpha binding protein rn
RAT230_2:1368169_AT protein kinase C, alpha binding protein rn
Gene Ontology
GO Molecular Function (view graph)
ID Description Evidence Links
5515 protein binding inferred from electronic annotation QuickGO AmiGO
Protein Similarities
Method ID Description E-Value
blast CAB16523 Hypothetical protein Y57G11C.22 [Caenorhabditis elegans] ref|NP_502796.1| Y57G11C.22 [Caenorhabditis elegans] 0.0
blast CAE73898 Hypothetical protein CBG21499 [Caenorhabditis briggsae] 0.0
blast CAB16522 Hypothetical protein Y57G11C.21 [Caenorhabditis elegans] ref|NP_502800.1| Y57G11C.21 [Caenorhabditis elegans] 1.0E-103
blast XP_613239 PREDICTED: similar to PRKCA-binding protein (Protein kinase C-alpha binding protein) (Protein interacting with C kinase 1) isoform 1 [Bos taurus] ref|XP_884154.1| PREDICTED: similar to PRKCA-binding protein (Protein kinase C-alpha binding protein) (Protein interacting with C kinase 1) isoform 11 [Bos taurus] ref|XP_871748.1| PREDICTED: similar to PRKCA-binding protein (Protein kinase C-alpha binding protein) (Protein interacting with C kinase 1) isoform 3 [Bos taurus] 2.0E-94
Protein Domains
Database ID Description E-Value
Pfam IPR001478 EMBL-EBI PDZ/DHR/GLGF domain 4.5E-9
Pfam IPR010504 EMBL-EBI Arfaptin-like 1.0E-126
Pfam IPR001478 EMBL-EBI PDZ/DHR/GLGF domain 8.2E-6
Pfam IPR010504 EMBL-EBI Arfaptin-like 1.0E-126
Sequence
Target Sequence 
>C. ELEGANS:191966_AT
ttgtaccggacactcgtttgacgattaaaaaatatttggatgtgaaatatgaatatttgt
cgtattgcttgaaactgaaagaaatggatgacgaggaagtggaatttgtggcaattcagg
agccgctgtatcgagttgaaactggaaattatgaatatagagtaatgctccgttgccgtc
aagagtgccgtgctcggtttatgaaaatgcgtgatgacgtcatggtgaaaatcgagctgc
tcgatcaaaaacacgtcagagatattgctcaacacctagcgatctttgcaaaaactatgg
caaaatgtcaacaggaatgtgcagaaatactgaaagaacggattgatgtaccaattgaaa
ttgatttggaacagttgaatttaaatatgaatacaagtgatggaaaagcaaatggagaag
aggaaatgggacaagatgcaatagttttgaatgataatccattggaaggcgatctgattg
atgtgaatgacataggatcatctacagaattcaatgaacctcgaatatctctccgccgtg
attctcaaaacgacacttctcagccactattgggagcaccggattcaccattg

BLASTn GenBank NR
Probe Info
Probe Sequence(5'-3') Probe X Probe Y Probe Interrogation
Position 		Strandedness
TTGTACCGGACACTCGTTTGACGAT 151 697 725 Antisense
AATTTGTGGCAATTCAGGAGCCGCT 193 175 827 Antisense
GGAGCCGCTGTATCGAGTTGAAACT 442 521 843 Antisense
TAATGCTCCGTTGCCGTCAAGAGTG 254 631 887 Antisense
GTCAAGAGTGCCGTGCTCGGTTTAT 406 463 902 Antisense
AGCTGCTCGATCAAAAACACGTCAG 534 79 959 Antisense
TGCTCAACACCTAGCGATCTTTGCA 261 581 990 Antisense
CAATGAACCTCGAATATCTCTCCGC 368 183 1236 Antisense
TCTCCGCCGTGATTCTCAAAACGAC 66 611 1254 Antisense
ACACTTCTCAGCCACTATTGGGAGC 34 111 1277 Antisense
ATTGGGAGCACCGGATTCACCATTG 196 3 1293 Antisense
Sequence Source Affymetrix Proprietary Database