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[191965_at] endoplasmin precursor (GRP94)

Description T05E11.3 /REP_DB=WormBase Gene ID /WP=CE06362 /TR=Q22235 /GB=CAA92973.1 /SUBMIT=HINXTON /CHR=4 /FEA=Sanger Annotation /DEF=endoplasmin precursor (GRP94)
Cluster 6grp_highest_10_10 > 02      6grp_high1_10_10 > 11      4grp_highest_8_8 > 11      4grp_high_8_8 > 47      6grp_highest_nonorm > 06      6grp_total > 23      4grp_total > 40      6grp_high1_sub > De      6grp_total_sub > Decrease      6grp_rule_based > S1      4grp_rule_based > L3      

Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 5194
1 2 3 4 range
A 7746.6
(-3)
P 		10609.1
(0.6)
P 		12507.7
(3)
P 		9723.4
(-0.5)
P 		4761
B 7729.3
(-3)
P 		11741.3
(1.8)
P 		12709.1
(3)
P 		9934.9
(-0.3)
P 		4980
C 7515.2
(-3)
P 		10602.3
(1.5)
P 		11597
(3)
P 		9048.9
(-0.7)
P 		4082
avr 7663.7
(-3) 		10984.2
(1.3) 		12271.3
(3) 		9569.1
(-0.5) 		4608

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 5989
1 2 3 4 5 6 range
A 12299.6
(3)
P 		12059.8
(2.7)
P 		9241.5
(-0.9)
P 		10947.5
(1.3)
P 		7614.5
(-3)
P 		7666.7
(-2.9)
P 		4685
B 11507
(3)
P 		10076.9
(1.2)
P 		9896.4
(0.9)
P 		10039.2
(1.1)
P 		7831.5
(-1.7)
P 		6807.7
(-3)
P 		4699
C 11609.9
(1.6)
P 		10184.5
(0)
P 		12797.1
(3)
P 		10380.3
(0.2)
P 		9227.3
(-1.1)
P 		7545.7
(-3)
P 		5251
avr 11805.5
(3) 		10773.7
(1.6) 		10645
(1.4) 		10455.7
(1.2) 		8224.4
(-1.8) 		7340
(-3) 		4466
No Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 2619
1 2 3 4 range
A 2820.6
(1.5)
P 		2303
(-0.1)
P 		3269.8
(3)
P 		1423.3
(-3)
P 		1847
B 2464.8
(-0.5)
P 		2899.8
(2.7)
P 		2945
(3)
P 		2117.1
(-3)
P 		828
C 2487.7
(-0.7)
P 		3048.2
(0.6)
P 		4041.9
(3)
P 		1525.8
(-3)
P 		2516
avr 2591
(0.1) 		2750.3
(0.7) 		3418.9
(3) 		1688.7
(-3) 		1730

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 2437
1 2 3 4 5 6 range
A 2267.3
(-2)
P 		4289
(3)
P 		2012.6
(-2.6)
P 		2776.5
(-0.7)
P 		2297.7
(-1.9)
P 		1866.6
(-3)
P 		2422
B 4003.9
(3)
P 		3354.2
(0.6)
P 		2403.1
(-3)
P 		2659
(-2)
P 		3181.9
(-0.1)
P 		2538.6
(-2.5)
P 		1601
C 4303.3
(3)
P 		3107.6
(-0.2)
P 		3257.1
(0.2)
P 		2087.5
(-3)
P 		2985.8
(-0.6)
P 		2526
(-1.8)
P 		2216
avr 3524.8
(2.7) 		3583.6
(3) 		2557.6
(-1.8) 		2507.7
(-2.1) 		2821.8
(-0.6) 		2310.4
(-3) 		1273
NetAffx Links Cluster Members
Consensus/Exemplar
GeneChip Array Information
Probe Set ID 191965_at
GeneChip Array C. elegans Genome Array
Organism Common Name Nematode
Probe Design Information
Transcript ID(Array Design) affy.Ce.9189
Sequence Type Exemplar sequence
Representative Public ID T05E11.3 NCBI
Target Description T05E11.3 /REP_DB=WormBase Gene ID /WP=CE06362 /TR=Q22235 /GB=CAA92973.1 /SUBMIT=HINXTON /CHR=4 /FEA=Sanger Annotation /DEF=endoplasmin precursor (GRP94)
Cluster Evidence This cluster is supported by a Sanger Annotation.
Annotation Method Description
Annotation Description This probe set was annotated using the Matching Probes based pipeline to a RefSeq identifier using 1 transcript(s).
Annotation Grade This is a grade A annotation.
Annotation Transcript Cluster (# of Matching Probes) NM_069679(11)
Transcript Assignments
Representative
Transcript		 Description Matching Probes Related Probesets by Grade
NM_069679 NCBI Caenorhabditis elegans T05E11.3 (T05E11.3) mRNA, complete cds. 11/11 None
SNAP00000031863 ENSEMBL cdna:SNAP chromosome:CEL140:IV:11119423:11122910:1 11/11 None
GENEFINDER00000031874 ENSEMBL cdna:GeneFinder chromosome:CEL140:IV:11119423:11122910:1 11/11 None
T05E11.3.1 ENSEMBL cdna:known chromosome:CEL140:IV:11119333:11123126:1 gene:T05E11.3 11/11 None
T05E11.3.2 ENSEMBL cdna:known chromosome:CEL140:IV:11119347:11123097:1 gene:T05E11.3 11/11 None
Annotation Notes
There are no noteworthy cross hybridizing mRNAs found for this probe set.
Genomic Alignment of Consensus/Exemplar Sequence
Assembly Wormbase March 2004
Alignment(s)
Position Identity Coverage Cytoband
chrIV:11119428-11122916(+) 100.0 100.0
Public Domain and Genome References
Gene Title endoplasmin precursor (GRP94)
Ensembl T05E11.3
Entrez Gene 178014 Entrez gene
SwissProt Q22235 EMBL-EBI
WormBase CE06362 Wormbase
Functional Annotations
Ortholog
ID Title Organism
ATGENOME1:16448_G_AT shepherd protein (SHD) / clavata formation protein, putative at
ATGENOME1:16447_AT shepherd protein (SHD) / clavata formation protein, putative at
ATH1-121501:254166_AT shepherd protein (SHD) / clavata formation protein, putative at
CANINE:1582369_AT tumor rejection antigen (gp96) 1 cfa
CANINE_2:CFA.3896.1.S1_S_AT tumor rejection antigen (gp96) 1 cfa
CANINE_2:CFAAFFX.12023.1.S1_AT tumor rejection antigen (gp96) 1 cfa
DROSOPHILA_2:1636528_AT Glycoprotein 93 dm
DROSGENOME1:154182_AT Glycoprotein 93 dm
CHICKEN:GGA.4724.1.S1_AT tumor rejection antigen (gp96) 1 gga
CHICKEN:GGA.4724.1.S2_AT tumor rejection antigen (gp96) 1 gga
HG-U133_PLUS_2:200599_S_AT tumor rejection antigen (gp96) 1 hs
HG-U133A:200599_S_AT tumor rejection antigen (gp96) 1 hs
HG-FOCUS:200599_S_AT tumor rejection antigen (gp96) 1 hs
HG-U133A_2:200599_S_AT tumor rejection antigen (gp96) 1 hs
HG-U95AV2:442_AT tumor rejection antigen (gp96) 1 hs
HC-G110:442_AT tumor rejection antigen (gp96) 1 hs
HG-U133_PLUS_2:200598_S_AT tumor rejection antigen (gp96) 1 hs
HG-U133A_2:200598_S_AT tumor rejection antigen (gp96) 1 hs
HG-U133A:200598_S_AT tumor rejection antigen (gp96) 1 hs
HU35KSUBA:RC_D51235_F_AT tumor rejection antigen (gp96) 1 hs
HU35KSUBC:RC_R20669_F_AT tumor rejection antigen (gp96) 1 hs
HU35KSUBC:RC_H99801_S_AT tumor rejection antigen (gp96) 1 hs
HUGENEFL:X15187_AT tumor rejection antigen (gp96) 1 hs
HG-U133_PLUS_2:216449_X_AT tumor rejection antigen (gp96) 1 hs
HG-U133A_2:216449_X_AT tumor rejection antigen (gp96) 1 hs
HG-U133A:216449_X_AT tumor rejection antigen (gp96) 1 hs
U133_X3P:G4507676_3P_A_AT tumor rejection antigen (gp96) 1 hs
U133_X3P:HS.82689.0.S1_3P_A_AT tumor rejection antigen (gp96) 1 hs
U133_X3P:HS.288528.0.S1_3P_S_AT tumor rejection antigen (gp96) 1 hs
U133_X3P:216449_3P_X_AT tumor rejection antigen (gp96) 1 hs
HG-U133_PLUS_2:216450_X_AT tumor rejection antigen (gp96) 1 hs
HG-U133A_2:216450_X_AT tumor rejection antigen (gp96) 1 hs
HG-U133A:216450_X_AT tumor rejection antigen (gp96) 1 hs
U133_X3P:HS.192374.0.S1_3P_AT Tumor rejection antigen (gp96) 1 hs
HG-U133_PLUS_2:239451_AT Tumor rejection antigen (gp96) 1 hs
HG-U133B:239451_AT Tumor rejection antigen (gp96) 1 hs
HG-U95E:68624_AT Tumor rejection antigen (gp96) 1 hs
MOUSE430_2:1415889_A_AT tumor rejection antigen gp96 mm
MOUSE430A_2:1415889_A_AT tumor rejection antigen gp96 mm
MOE430A:1415889_A_AT tumor rejection antigen gp96 mm
MOUSE430A_2:1438040_A_AT tumor rejection antigen gp96 mm
MOUSE430_2:1438040_A_AT tumor rejection antigen gp96 mm
MOE430A:1438040_A_AT tumor rejection antigen gp96 mm
MU11KSUBB:MSA.27657.0_F_AT tumor rejection antigen gp96 mm
MU11KSUBB:MSA.11833.0_F_AT tumor rejection antigen gp96 mm
MU11KSUBB:MSA.12687.0_S_AT tumor rejection antigen gp96 mm
MU11KSUBB:MSA.10652.0_F_AT tumor rejection antigen gp96 mm
MG-U74AV2:160499_AT tumor rejection antigen gp96 mm
MG-U74CV2:167108_R_AT Tumor rejection antigen gp96, mRNA (cDNA clone MGC:6208 IMAGE:3587178) mm
MU19KSUBA:TC15686_AT Tumor rejection antigen gp96, mRNA (cDNA clone MGC:6208 IMAGE:3587178) mm
MU19KSUBA:TC16545_AT Tumor rejection antigen gp96, mRNA (cDNA clone MGC:6208 IMAGE:3587178) mm
MU19KSUBA:TC16597_S_AT Tumor rejection antigen gp96, mRNA (cDNA clone MGC:6208 IMAGE:3587178) mm
MU19KSUBB:TC29664_S_AT Tumor rejection antigen gp96, mRNA (cDNA clone MGC:6208 IMAGE:3587178) mm
MU19KSUBB:TC33238_AT Tumor rejection antigen gp96, mRNA (cDNA clone MGC:6208 IMAGE:3587178) mm
RT-U34:AA685903_AT tumor rejection antigen gp96 (predicted) rn
RG-U34A:AA685903_AT tumor rejection antigen gp96 (predicted) rn
RG-U34A:S69316_S_AT tumor rejection antigen gp96 (predicted) rn
RG-U34A:S69315_AT tumor rejection antigen gp96 (predicted) rn
RG-U34B:RC_AA963782_AT tumor rejection antigen gp96 (predicted) rn
RG-U34C:RC_AI230121_AT tumor rejection antigen gp96 (predicted) rn
RAE230A:1388331_AT tumor rejection antigen gp96 (predicted) rn
RAT230_2:1388331_AT tumor rejection antigen gp96 (predicted) rn
RG-U34C:RC_AI101926_AT Tumor rejection antigen gp96 (predicted) rn
Gene Ontology
GO Biological Process (view graph)
ID Description Evidence Links
6457 protein folding inferred from electronic annotation QuickGO AmiGO
GO Molecular Function (view graph)
ID Description Evidence Links
5524 ATP binding inferred from electronic annotation QuickGO AmiGO
Protein Similarities
Method ID Description E-Value
blast CAA92973 Hypothetical protein T05E11.3 [Caenorhabditis elegans] ref|NP_502080.1| T05E11.3 [Caenorhabditis elegans] 0.0
blast CAE62006 Hypothetical protein CBG06014 [Caenorhabditis briggsae] 0.0
blast XP_576206 PREDICTED: tumor rejection antigen gp96 (predicted) [Rattus norvegicus] 0.0
Protein Domains
Database ID Description E-Value
Pfam IPR001404 EMBL-EBI Heat shock protein Hsp90 1.0E-126
Pfam IPR003594 EMBL-EBI ATP-binding region, ATPase-like 1.3E-13
Sequence
Target Sequence 
>C. ELEGANS:191965_AT
ggccaaggaagcccacaagggtcttgaagaggagttcaagccacttactgactggctcaa
ggaaactgcactcaaggatctgatcgagaaagcagttgtttctcaacgtcttgtcaaatc
accatctgcccttgttgcctcttcctacggatggtctggaaacatggagcgcattatgaa
gtcgcaagcttatgctaaggcaaaggatccaactcaagacttctatgctactcagaaaaa
gacattcgagattaacccacgccatccagttatcaaggagcttctcaagagagtcactgc
ttctgaagaagataccaccgctgcttctactgccaagcttctcttcgaaactgccactct
tcgttctggattctcacttcaagatcaagttggttttgctgatagaatcgaagctgtcct
tcgccaatcgctcgatgtttcccaagatgctcaagttgaaaccgaacagcatattgaaga
ggctgaaccagagccagaagccgctgaag

BLASTn GenBank NR
Probe Info
Probe Sequence(5'-3') Probe X Probe Y Probe Interrogation
Position 		Strandedness
GGCCAAGGAAGCCCACAAGGGTCTT 32 543 1752 Antisense
GAGGAGTTCAAGCCACTTACTGACT 641 403 1780 Antisense
GACTGGCTCAAGGAAACTGCACTCA 596 375 1801 Antisense
CAACGTCTTGTCAAATCACCATCTG 6 189 1855 Antisense
GGATCCAACTCAAGACTTCTATGCT 602 511 1956 Antisense
AGACATTCGAGATTAACCCACGCCA 640 69 1991 Antisense
CCCACGCCATCCAGTTATCAAGGAG 301 259 2007 Antisense
GCTTCTCAAGAGAGTCACTGCTTCT 11 307 2031 Antisense
AAGAAGATACCACCGCTGCTTCTAC 669 151 2057 Antisense
CTCGATGTTTCCCAAGATGCTCAAG 74 233 2182 Antisense
GAACCAGAGCCAGAAGCCGCTGAAG 350 345 2236 Antisense
Sequence Source Affymetrix Proprietary Database