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[191947_at] seven transmembrane receptor

Description T22D1.12 /REP_DB=WormBase Gene ID /WP=CE17256 /TR=Q9GZG8 /GB=AAF98633.1 /SUBMIT=ST.LOUIS /CHR=4 /FEA=Sanger Annotation /DEF=seven transmembrane receptor
Cluster 6grp_highest_10_10 > 40      6grp_high1_10_10 > 05      4grp_highest_8_8 > 52      4grp_high_8_8 > 16      6grp_highest_nonorm > 50      6grp_total > 05      4grp_total > 31      6grp_highest_sub > De      6grp_high1_sub > De      

Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 461
1 2 3 4 range
A 798.6
(3)
P 		346.6
(-3)
P 		359.6
(-2.8)
P 		550.6
(-0.3)
P 		452
B 717.1
(3)
P 		343.1
(-3)
P 		352.7
(-2.8)
P 		469.9
(-1)
P 		374
C 652
(3)
P 		374.9
(-2.3)
P 		337.4
(-3)
P 		575.2
(1.5)
P 		315
avr 722.6
(3) 		354.9
(-2.9) 		349.9
(-3) 		531.9
(-0.1) 		373

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 491
1 2 3 4 5 6 range
A 808.9
(3)
P 		558.3
(-0.1)
P 		427.1
(-1.7)
P 		413.7
(-1.8)
P 		515.9
(-0.6)
P 		317.8
(-3)
P 		491
B 725.6
(3)
P 		651.7
(1.8)
P 		526.3
(-0.3)
P 		363.7
(-3)
P 		417.4
(-2.1)
P 		399
(-2.4)
P 		362
C 579.6
(3)
P 		572.8
(2.8)
P 		468.2
(-0)
P 		359.4
(-3)
P 		376.6
(-2.5)
P 		358.2
(-3)
P 		221
avr 704.7
(3) 		594.3
(1.1) 		473.9
(-1) 		378.9
(-2.6) 		436.6
(-1.6) 		358.3
(-3) 		346
No Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 216
1 2 3 4 range
A 290.8
(3)
P 		75.2
(-3)
P 		94
(-2.5)
P 		80.6
(-2.8)
P 		216
B 228.7
(3)
P 		84.7
(-2.9)
P 		81.7
(-3)
P 		100.1
(-2.2)
P 		147
C 215.8
(3)
P 		107.8
(-2.5)
P 		117.6
(-2)
P 		97
(-3)
P 		119
avr 245.1
(3) 		89.2
(-3) 		97.8
(-2.7) 		92.6
(-2.9) 		156

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 180
1 2 3 4 5 6 range
A 149.1
(0.6)
P 		198.5
(3)
P 		93
(-2.2)
P 		104.9
(-1.6)
P 		155.7
(0.9)
P 		77.4
(-3)
P 		121
B 252.5
(3)
P 		216.9
(1.6)
P 		127.8
(-1.8)
P 		96.3
(-3)
P 		169.6
(-0.2)
P 		148.8
(-1)
P 		156
C 214.8
(3)
P 		174.8
(1.3)
P 		119.2
(-1)
P 		72.3
(-3)
P 		121.9
(-0.9)
P 		119.9
(-1)
P 		143
avr 205.5
(3) 		196.7
(2.5) 		113.3
(-1.8) 		91.2
(-3) 		149.1
(0) 		115.4
(-1.7) 		114
NetAffx Links Cluster Members
Consensus/Exemplar
GeneChip Array Information
Probe Set ID 191947_at
GeneChip Array C. elegans Genome Array
Organism Common Name Nematode
Probe Design Information
Transcript ID(Array Design) affy.Ce.9463
Sequence Type Exemplar sequence
Representative Public ID T22D1.12 NCBI
Target Description T22D1.12 /REP_DB=WormBase Gene ID /WP=CE17256 /TR=Q9GZG8 /GB=AAF98633.1 /SUBMIT=ST.LOUIS /CHR=4 /FEA=Sanger Annotation /DEF=seven transmembrane receptor
Cluster Evidence This cluster is supported by a Sanger Annotation.
Annotation Method Description
Annotation Description This probe set was annotated using the Matching Probes based pipeline to a RefSeq identifier using 1 transcript(s).
Annotation Grade This is a grade A annotation.
Annotation Transcript Cluster (# of Matching Probes) NM_068670(11)
Transcript Assignments
Representative
Transcript		 Description Matching Probes Related Probesets by Grade
NM_068670 NCBI Caenorhabditis elegans T22D1.12 (T22D1.12) mRNA, complete cds. 11/11 None
T22D1.12 ENSEMBL cdna:known chromosome:CEL140:IV:6929072:6931102:-1 gene:T22D1.12 11/11 None
Annotation Notes
There are no noteworthy cross hybridizing mRNAs found for this probe set.
Genomic Alignment of Consensus/Exemplar Sequence
Assembly Wormbase March 2004
Alignment(s)
Position Identity Coverage Cytoband
chrIV:6929077-6931108(-) 100.0 100.0
Public Domain and Genome References
Gene Title seven transmembrane receptor
Ensembl T22D1.12
Entrez Gene 188742 Entrez gene
SwissProt Q9GZG8 EMBL-EBI
WormBase CE17256 Wormbase
Functional Annotations
Ortholog
ID Title Organism
CANINE_2:CFAAFFX.24701.1.S1_AT similar to Neuropeptide Y receptor type 4 (NPY4-R) (Pancreatic polypeptide receptor 1) (PP1) cfa
CHICKEN:GGAAFFX.3690.1.S1_AT pancreatic polypeptide receptor 1 gga
HG-U95AV2:34597_AT pancreatic polypeptide receptor 1 hs
HG-U133_PLUS_2:210956_AT pancreatic polypeptide receptor 1 hs
HG-U133A:210956_AT pancreatic polypeptide receptor 1 hs
HG-FOCUS:210956_AT pancreatic polypeptide receptor 1 hs
HG-U133A_2:210956_AT pancreatic polypeptide receptor 1 hs
HUGENEFL:U42387_AT pancreatic polypeptide receptor 1 hs
U133_X3P:G1314327_3P_AT pancreatic polypeptide receptor 1 hs
MOUSE430_2:1422271_AT pancreatic polypeptide receptor 1 mm
MOE430A:1422271_AT pancreatic polypeptide receptor 1 mm
MOUSE430A_2:1422271_AT pancreatic polypeptide receptor 1 mm
MU11KSUBB:MSA.1928.0_S_AT pancreatic polypeptide receptor 1 mm
MG-U74AV2:101736_AT pancreatic polypeptide receptor 1 mm
RG-U34A:U42388_AT pancreatic polypeptide receptor 1 rn
RAE230A:1369189_AT pancreatic polypeptide receptor 1 rn
RAT230_2:1369189_AT pancreatic polypeptide receptor 1 rn
Gene Ontology
GO Biological Process (view graph)
ID Description Evidence Links
7186 G-protein coupled receptor protein signaling pathway inferred from electronic annotation QuickGO AmiGO
GO Cellular Component (view graph)
ID Description Evidence Links
16021 integral to membrane inferred from electronic annotation QuickGO AmiGO
GO Molecular Function (view graph)
ID Description Evidence Links
1584 rhodopsin-like receptor activity inferred from electronic annotation QuickGO AmiGO
4983 neuropeptide Y receptor activity inferred from electronic annotation QuickGO AmiGO
Protein Similarities
Method ID Description E-Value
blast AAF98633 Hypothetical protein T22D1.12 [Caenorhabditis elegans] ref|NP_501071.1| T22D1.12 [Caenorhabditis elegans] 0.0
blast CAE61776 Hypothetical protein CBG05736 [Caenorhabditis briggsae] 0.0
blast AAA82357 Hypothetical protein C25G6.5 [Caenorhabditis elegans] ref|NP_508234.1| C25G6.5 [Caenorhabditis elegans] sp|Q18179|YXX5_CAEEL Putative neuropeptide Y receptor (NPY-R) 2.0E-42
Protein Domains
Database ID Description E-Value
Pfam IPR000276 EMBL-EBI Rhodopsin-like GPCR superfamily 1.2E-24
Pfam IPR000276 EMBL-EBI Rhodopsin-like GPCR superfamily 2.2E-24
Trans Membrane
ID Number Of Domains Domain Boundaries
NP_501071.1 7 38-60,73-95,110-129,150-172,218-240,271-293,308-330
T22D1.12 7 38-60,73-95,110-129,150-172,218-240,271-293,308-330
Sequence
Target Sequence 
>C. ELEGANS:191947_AT
gcaactcccaaaatgctaacctattgcaaccgtcaagtgccagaaatatgtgcagagatg
caagaagcctgggataatgcaattgtctcaaaaaccacgtacacatttgtagtacttggt
attcaatatattctaccacttgctgccttggcatatgcatatttccaaatcgggtcaaca
attcaaaaacgatcaaaagtatcacgtacagtggatacaacaagaagaatgcaaatgcaa
aatagaaatcgaagagctcttttgttgctctttttgttagtactcacatatgccgtgtgt
tgggctccaatgaatatttatcatgttttgaatggtctcgagattattaactattcacaa
aatatgtacatcttctgtcatttggtcggaatctcttcaacgtgtgttaatccaatagta
tatgcactggtcaatgaatcatttagaaatgctttacaatcaatgattcttcaattccgc
ccgtgttacgtcacaactaccggtacagcagccaccaacgtgtatgcatattctgcgact
tcga

BLASTn GenBank NR
Probe Info
Probe Sequence(5'-3') Probe X Probe Y Probe Interrogation
Position 		Strandedness
GCAACTCCCAAAATGCTAACCTATT 600 309 568 Antisense
AACCTATTGCAACCGTCAAGTGCCA 117 147 585 Antisense
CAATATATTCTACCACTTGCTGCCT 527 179 691 Antisense
GCTGCCTTGGCATATGCATATTTCC 28 299 709 Antisense
TGTTGCTCTTTTTGTTAGTACTCAC 537 563 830 Antisense
ATATGCCGTGTGTTGGGCTCCAATG 230 21 855 Antisense
CATCTTCTGTCATTTGGTCGGAATC 457 213 936 Antisense
GTCGGAATCTCTTCAACGTGTGTTA 487 471 952 Antisense
GTGTTACGTCACAACTACCGGTACA 454 485 1050 Antisense
ACAGCAGCCACCAACGTGTATGCAT 430 107 1072 Antisense
GTGTATGCATATTCTGCGACTTCGA 144 485 1087 Antisense
Sequence Source Affymetrix Proprietary Database