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[191935_s_at]

Description T10A3.1 /REP_DB=WormBase Gene ID /WP=CE04931 /TR=Q22366 /GB=AAB37028.1 /SUBMIT=ST.LOUIS /CHR=X /FEA=Sanger Annotation /DEF=C2 domain of protein kinase C
Cluster 6grp_high1_10_10 > 15      6grp_total > 15      4grp_total > 47      6grp_cgc > 23      6grp_high1_sub > De      6grp_cgc_sub > De      6grp_total_sub > Decrease      4grp_rule_based > L1      

Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 499
1 2 3 4 range
A 725.3
(3)
P 		294
(-2.3)
A 		238.3
(-3)
A 		335.2
(-1.8)
A 		487
B 704.2
(3)
P 		359
(-1.5)
A 		247.8
(-3)
A 		318.1
(-2.1)
A 		456
C 737.7
(3)
P 		272.8
(-2.8)
A 		255.5
(-3)
A 		297.2
(-2.5)
A 		482
avr 722.4
(3) 		308.6
(-2.2) 		247.2
(-3) 		316.8
(-2.1) 		475

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 437
1 2 3 4 5 6 range
A 702.5
(3)
P 		570.7
(1.1)
P 		339.6
(-2.2)
M 		281.4
(-3)
A 		317.2
(-2.5)
P 		315.7
(-2.5)
A 		421
B 704.9
(3)
P 		609.9
(1.6)
P 		382.8
(-1.9)
P 		448.1
(-0.9)
P 		316.1
(-2.9)
P 		310
(-3)
P 		395
C 600.8
(2.2)
P 		652.9
(3)
P 		347.6
(-1.8)
A 		438.9
(-0.3)
P 		267.6
(-3)
A 		317.1
(-2.2)
P 		385
avr 669.4
(3) 		611.2
(2.1) 		356.7
(-2.1) 		389.5
(-1.5) 		300.3
(-3) 		314.3
(-2.8) 		369
No Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 215
1 2 3 4 range
A 264.1
(3)
P 		63.8
(-2.6)
A 		62.3
(-2.6)
A 		49.1
(-3)
A 		215
B 224.6
(3)
P 		88.7
(-1.9)
A 		57.4
(-3)
A 		67.8
(-2.6)
A 		167
C 244.2
(3)
P 		78.4
(-2.1)
A 		89
(-1.8)
A 		50.1
(-3)
A 		194
avr 244.3
(3) 		77
(-2.3) 		69.6
(-2.6) 		55.7
(-3) 		189

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 174
1 2 3 4 5 6 range
A 129.5
(-0.4)
P 		203
(3)
P 		74
(-2.9)
M 		71.4
(-3)
A 		95.7
(-1.9)
P 		76.9
(-2.7)
A 		132
B 245.3
(3)
P 		203
(1.3)
P 		93
(-3)
P 		118.7
(-2)
P 		128.4
(-1.6)
P 		115.6
(-2.1)
P 		152
C 222.7
(3)
P 		199.2
(2)
P 		88.5
(-2.9)
A 		88.3
(-2.9)
P 		86.6
(-3)
A 		106.1
(-2.1)
P 		136
avr 199.2
(2.9) 		201.7
(3) 		85.2
(-3) 		92.8
(-2.6) 		103.6
(-2.1) 		99.5
(-2.3) 		117
NetAffx Links Cluster Members
Consensus/Exemplar
Group Members
GeneChip Array Information
Probe Set ID 191935_s_at
GeneChip Array C. elegans Genome Array
Organism Common Name Nematode
Probe Design Information
Transcript ID(Array Design) affy.Ce.16168
Sequence Type Exemplar sequence
Representative Public ID T10A3.1 NCBI
Target Description T10A3.1 /REP_DB=WormBase Gene ID /WP=CE04931 /TR=Q22366 /GB=AAB37028.1 /SUBMIT=ST.LOUIS /CHR=X /FEA=Sanger Annotation /DEF=C2 domain of protein kinase C
Cluster Evidence This cluster is supported by a Sanger Annotation.
Annotation Method Description
Annotation Description This probe set was annotated using the Matching Probes based pipeline to a RefSeq identifier using 1 transcript(s).
Annotation Grade This is a grade A annotation.
Annotation Transcript Cluster (# of Matching Probes) NM_001029730(10), NM_171720(10)
Transcript Assignments
Representative
Transcript		 Description Matching Probes Related Probesets by Grade
NM_001029730 NCBI Caenorhabditis elegans UNCoordinated family member (unc-10) (unc-10) mRNA, complete cds. 10/11 None
NM_171720 NCBI Caenorhabditis elegans UNCoordinated family member (unc-10) (unc-10) mRNA, complete cds. 10/11 A 
T10A3.1b ENSEMBL cdna:known chromosome:CEL140:X:7272283:7280247:-1 gene:T10A3.1 10/11 A 
T10A3.1a ENSEMBL cdna:known chromosome:CEL140:X:7272494:7280247:-1 gene:T10A3.1 10/11 A 
Annotation Notes
There are no noteworthy cross hybridizing mRNAs found for this probe set.
Genomic Alignment of Consensus/Exemplar Sequence
Assembly Wormbase March 2004
Alignment(s)
Position Identity Coverage Cytoband
chrX:7272492-7276512(-) 100.0 100.0
Public Domain and Genome References
Ensembl T10A3.1
Functional Annotations
Protein Similarities
Method ID Description E-Value
blast AAM69088 Uncoordinated protein 10, isoform b [Caenorhabditis elegans] ref|NP_001024901.1| UNCoordinated family member (unc-10) [Caenorhabditis elegans] 0.0
blast AAB37028 Uncoordinated protein 10, isoform a [Caenorhabditis elegans] ref|NP_741831.1| UNCoordinated family member (unc-10) [Caenorhabditis elegans] gb|AAK49331.1| Rab3-interacting molecule UNC-10 [Caenorhabditis elegans] sp|Q22366|RIM_CAEEL Rab-3 interacting molecule unc-10 (Rim) (Uncoordinated protein 10) 0.0
blast CAE65866 Hypothetical protein CBG11009 [Caenorhabditis briggsae] 0.0
Protein Domains
Database ID Description E-Value
Pfam IPR001478 EMBL-EBI PDZ/DHR/GLGF domain 4.9E-9
Pfam IPR000008 EMBL-EBI C2 domain 1.1E-26
Pfam IPR000008 EMBL-EBI C2 domain 9.3E-16
Sequence
Target Sequence 
>C. ELEGANS:191935_S_AT
ttgtcttcagatcggctcaccgaacccactcctccctttctgaagcaagccagcaaggaa
agcactgattctgctcactcagacaattggcttccagtgctcgctgatggtcctcttggt
acatttgtcgacaatcttggtccgggtcaggttgtcggtcgtcaagtgcttgcctcaccg
gtgctaggagagattcagatcgctttaatggccggtagaagcggcattgacgtcgaaatt
atcaaagctaaaaatctggtagtaaaaccgggagtgaaacttactttttcagctccctat
gtaaaagtgtatcttatggagggcaaacaatgcattgccaaagcaaagacaaacgccgcc
actaaaacaactagtccattattccagcaacatttaatatttaatgatagtccaaagaaa
aaaacgcttcaggtaacagtgcttggtgattacggtcgtatggaaagaaaagtattcatg
gggatttcgcaaatccgattagaagacctcgaactcggatctcaaccactaatagggtgg
tataaactgtttcatagttcttcgcttgct

BLASTn GenBank NR
Probe Info
Probe Sequence(5'-3') Probe X Probe Y Probe Interrogation
Position 		Strandedness
TTGTCTTCAGATCGGCTCACCGAAC 602 703 1948 Antisense
GAAAGCACTGATTCTGCTCACTCAG 660 359 2005 Antisense
GATGGTCCTCTTGGTACATTTGTCG 62 409 2053 Antisense
CAATCTTGGTCCGGGTCAGGTTGTC 548 179 2079 Antisense
TCAGGTTGTCGGTCGTCAAGTGCTT 262 621 2094 Antisense
CTTGCCTCACCGGTGCTAGGAGAGA 63 219 2116 Antisense
CTTACTTTTTCAGCTCCCTATGTAA 124 223 2227 Antisense
AACAACTAGTCCATTATTCCAGCAA 298 135 2313 Antisense
AACGCTTCAGGTAACAGTGCTTGGT 188 145 2370 Antisense
GAAGACCTCGAACTCGGATCTCAAC 544 339 2449 Antisense
ACTGTTTCATAGTTCTTCGCTTGCT 433 97 2493 Antisense
Sequence Source Affymetrix Proprietary Database