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[191927_at] mitochondrial carrier protein

Description R07B7.10 /REP_DB=WormBase Gene ID /WP=CE06272 /TR=Q21800 /GB=CAB00119.1 /SUBMIT=HINXTON /CHR=5 /FEA=Sanger Annotation /DEF=mitochondrial carrier protein
Cluster 6grp_highest_10_10 > 36      6grp_high1_10_10 > 62      4grp_highest_8_8 > 18      4grp_high_8_8 > 63      6grp_highest_nonorm > 90      6grp_total > 62      4grp_total > 48      6grp_highest_sub > 03      6grp_high1_sub > 03      6grp_total_sub > Hat      6grp_rule_based > S3      4grp_rule_based > L3      

Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 183
1 2 3 4 range
A 108.6
(-0.4)
P 		125.6
(0.4)
P 		178.7
(3)
P 		56.3
(-3)
P 		122
B 117.5
(-3)
P 		163.4
(0.9)
P 		188.7
(3)
P 		121.9
(-2.6)
P 		71
C 118
(-3)
P 		171.2
(-0.4)
P 		238.8
(3)
P 		131.3
(-2.3)
P 		121
avr 114.7
(-2.3) 		153.4
(0) 		202.1
(3) 		103.2
(-3) 		99

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 164
1 2 3 4 5 6 range
A 72.6
(-3)
P 		112.5
(-0.8)
P 		182.7
(3)
P 		180.9
(2.9)
P 		105.3
(-1.2)
P 		105.1
(-1.2)
P 		110
B 79.9
(-3)
P 		140.9
(-0.7)
P 		236.4
(3)
P 		170
(0.5)
P 		122.1
(-1.4)
P 		106.1
(-2)
P 		157
C 112
(-3)
P 		154.7
(-0.5)
P 		213.3
(3)
P 		164
(0.1)
P 		150.2
(-0.7)
P 		116.8
(-2.7)
P 		101
avr 88.2
(-3) 		136
(-0.7) 		210.8
(3) 		171.6
(1.1) 		125.9
(-1.2) 		109.3
(-2) 		123
No Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 75
1 2 3 4 range
A 39.5
(1.9)
P 		27.3
(-0)
P 		46.7
(3)
P 		8.2
(-3)
P 		39
B 37.5
(0.9)
P 		40.4
(1.9)
P 		43.7
(3)
P 		26
(-3)
P 		18
C 39.1
(-1.3)
P 		49.2
(-0.3)
P 		83.2
(3)
P 		22.1
(-3)
P 		61
avr 38.7
(0.1) 		39
(0.1) 		57.9
(3) 		18.8
(-3) 		39

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 44
1 2 3 4 5 6 range
A 13.4
(-3)
P 		40
(1.9)
P 		39.8
(1.9)
P 		45.9
(3)
P 		31.8
(0.4)
P 		25.6
(-0.7)
P 		33
B 27.8
(-3)
P 		46.9
(0.9)
P 		57.4
(3)
P 		45
(0.5)
P 		49.6
(1.4)
P 		39.6
(-0.6)
P 		30
C 41.5
(-0.6)
P 		47.2
(1)
P 		54.3
(3)
P 		33
(-3)
P 		48.6
(1.4)
P 		39.1
(-1.3)
P 		21
avr 27.6
(-3) 		44.7
(1.5) 		50.5
(3) 		41.3
(0.6) 		43.3
(1.1) 		34.8
(-1.1) 		23
NetAffx Links Cluster Members
Consensus/Exemplar
GeneChip Array Information
Probe Set ID 191927_at
GeneChip Array C. elegans Genome Array
Organism Common Name Nematode
Probe Design Information
Transcript ID(Array Design) affy.Ce.12776
Sequence Type Exemplar sequence
Representative Public ID R07B7.10 NCBI
Target Description R07B7.10 /REP_DB=WormBase Gene ID /WP=CE06272 /TR=Q21800 /GB=CAB00119.1 /SUBMIT=HINXTON /CHR=5 /FEA=Sanger Annotation /DEF=mitochondrial carrier protein
Cluster Evidence This cluster is supported by a Sanger Annotation.
Annotation Method Description
Annotation Description This probe set was annotated using the Matching Probes based pipeline to a RefSeq identifier using 1 transcript(s).
Annotation Grade This is a grade A annotation.
Annotation Transcript Cluster (# of Matching Probes) NM_073629(11)
Transcript Assignments
Representative
Transcript		 Description Matching Probes Related Probesets by Grade
NM_073629 NCBI Caenorhabditis elegans R07B7.10 (R07B7.10) mRNA, complete cds. 11/11 None
SNAP00000027091 ENSEMBL cdna:SNAP chromosome:CEL140:V:12087014:12088888:1 11/11 None
GENEFINDER00000027104 ENSEMBL cdna:GeneFinder chromosome:CEL140:V:12087014:12088888:1 11/11 None
R07B7.10 ENSEMBL cdna:known chromosome:CEL140:V:12087014:12088888:1 gene:R07B7.10 11/11 None
Annotation Notes
There are no noteworthy cross hybridizing mRNAs found for this probe set.
Genomic Alignment of Consensus/Exemplar Sequence
Assembly Wormbase March 2004
Alignment(s)
Position Identity Coverage Cytoband
chrV:12087013-12088888(+) 100.0 100.0
Public Domain and Genome References
Gene Title mitochondrial carrier protein
Ensembl R07B7.10
Entrez Gene 187658 Entrez gene
SwissProt Q21800 EMBL-EBI
WormBase CE35596 Wormbase
Functional Annotations
Ortholog
ID Title Organism
CANINE_2:CFAAFFX.21042.1.S1_AT similar to mitochondrial hepatocellular carcinoma-downregulated carrier protein cfa
MOE430A:1426883_AT expressed sequence AW491445 mm
MOUSE430A_2:1426883_AT expressed sequence AW491445 mm
MOUSE430_2:1426883_AT expressed sequence AW491445 mm
MG-U74AV2:161640_AT expressed sequence AW491445 mm
MU19KSUBB:TC28804_AT Expressed sequence AW491445 (AW491445), mRNA mm
MU11KSUBA:D17966_RC_AT Expressed sequence AW491445 (AW491445), mRNA mm
Gene Ontology
GO Biological Process (view graph)
ID Description Evidence Links
6810 transport inferred from electronic annotation QuickGO AmiGO
GO Cellular Component (view graph)
ID Description Evidence Links
5743 mitochondrial inner membrane inferred from electronic annotation QuickGO AmiGO
16020 membrane inferred from electronic annotation QuickGO AmiGO
GO Molecular Function (view graph)
ID Description Evidence Links
5215 transporter activity inferred from electronic annotation QuickGO AmiGO
5488 binding inferred from electronic annotation QuickGO AmiGO
Protein Similarities
Method ID Description E-Value
blast CAB00119 Hypothetical protein R07B7.10 [Caenorhabditis elegans] ref|NP_506030.2| R07B7.10 [Caenorhabditis elegans] 1.0E-158
blast CAE75385 Hypothetical protein CBG23372 [Caenorhabditis briggsae] 1.0E-150
blast CAE75385 Hypothetical protein CBG23372 [Caenorhabditis briggsae] 1.0E-149
blast NP_598915 hypothetical protein LOC107375 [Mus musculus] gb|AAH37680.1| Expressed sequence AW491445 [Mus musculus] dbj|BAE33419.1| unnamed protein product [Mus musculus] dbj|BAE41428.1| unnamed protein product [Mus musculus] 1.0E-42
blast NP_598915 hypothetical protein LOC107375 [Mus musculus] gb|AAH37680.1| Expressed sequence AW491445 [Mus musculus] dbj|BAE33419.1| unnamed protein product [Mus musculus] dbj|BAE41428.1| unnamed protein product [Mus musculus] 2.0E-41
Protein Domains
Database ID Description E-Value
Pfam IPR001993 EMBL-EBI Mitochondrial substrate carrier 1.0E-20
Pfam IPR001993 EMBL-EBI Mitochondrial substrate carrier 1.2E-12
Pfam IPR001993 EMBL-EBI Mitochondrial substrate carrier 3.3E-22
Pfam IPR001993 EMBL-EBI Mitochondrial substrate carrier 2.0E-16
Pfam IPR001993 EMBL-EBI Mitochondrial substrate carrier 1.2E-12
Pfam IPR001993 EMBL-EBI Mitochondrial substrate carrier 3.3E-22
Trans Membrane
ID Number Of Domains Domain Boundaries
NP_506030.2 4 5-22,51-73,100-122,255-277
R07B7.10 4 5-22,51-73,100-122,255-277
SNAP00000027091 4 5-22,51-73,100-122,255-277
GENEFINDER00000027104 4 5-27,103-125,152-174,307-329
Sequence
Target Sequence 
>C. ELEGANS:191927_AT
aagtcggaccagttattcctgtggaattgttaaagaccaagcttcaggttcaaagagaaa
acattggtcatttctcaaaacactcaagaaatctctacgctggtccattagagtgtgctc
gggagactgttcgtgctgaaggagtgcgtggattattcaaaggaggaagtgttgtttttt
gccgagataatattggatacctcttctacattccagtatatgaaggacttagccgttact
ttagaagccataatttagagaatacatggacgcagctttttgctggaggttgtgctggag
tcagtggatggatttctgtgtgcccgttggaagttgtgaaaaaccggattcaagctgata
aaagccataaaacattatccccaaaagaaatgactctaaaaatctatcgagaagacggtc
tccgagcattttatcgtggtggatgggcgatttcactccg

BLASTn GenBank NR
Probe Info
Probe Sequence(5'-3') Probe X Probe Y Probe Interrogation
Position 		Strandedness
AAGTCGGACCAGTTATTCCTGTGGA 487 157 503 Antisense
ACTCAAGAAATCTCTACGCTGGTCC 415 99 584 Antisense
ACGCTGGTCCATTAGAGTGTGCTCG 538 91 599 Antisense
CTCGGGAGACTGTTCGTGCTGAAGG 624 231 620 Antisense
GAGGAAGTGTTGTTTTTTGCCGAGA 647 403 665 Antisense
GATACCTCTTCTACATTCCAGTATA 387 425 698 Antisense
GAGAATACATGGACGCAGCTTTTTG 509 391 760 Antisense
TTTGCTGGAGGTTGTGCTGGAGTCA 480 667 781 Antisense
AGTGGATGGATTTCTGTGTGCCCGT 518 59 805 Antisense
GACGGTCTCCGAGCATTTTATCGTG 19 377 916 Antisense
GTGGTGGATGGGCGATTTCACTCCG 9 489 938 Antisense
Sequence Source Affymetrix Proprietary Database