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[191926_s_at] myosin heavy chain

Description F11C3.3 /REP_DB=WormBase Gene ID /WP=CE09349 /GEN=unc-54 /TR=O02244 /GB=CAB05505.1 /SUBMIT=HINXTON /CHR=1 /FEA=Sanger Annotation /DEF=myosin heavy chain
Cluster 6grp_highest_10_10 > 30      6grp_high1_10_10 > 04      4grp_highest_8_8 > 32      4grp_high_8_8 > 51      6grp_highest_nonorm > 06      6grp_total > 24      4grp_total > 52      6grp_highest_sub > De      6grp_cgc > 21      6grp_high1_sub > De      6grp_cgc_sub > De      6grp_total_sub > Decrease      4grp_rule_based > L2      

Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 13270
1 2 3 4 range
A 13813
(2.7)
P 		14561.5
(3)
P 		11084
(1.4)
P 		1496.4
(-3)
P 		13065
B 11939.4
(3)
P 		10873.6
(2.4)
P 		10650.1
(2.3)
P 		1361.6
(-3)
P 		10578
C 10306.5
(2.6)
P 		10871.6
(3)
P 		10300.8
(2.6)
P 		1291.7
(-3)
P 		9580
avr 12019.6
(3) 		12102.2
(3) 		10678.3
(2.2) 		1383.2
(-3) 		10719

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 9913
1 2 3 4 5 6 range
A 14372.3
(3)
P 		12149.7
(0.8)
P 		8226.5
(-3)
P 		9589
(-1.7)
P 		9074
(-2.2)
P 		8556.3
(-2.7)
P 		6146
B 13562.8
(3)
P 		11044.6
(1)
P 		12049.5
(1.8)
P 		8825.2
(-0.7)
P 		6898
(-2.2)
P 		5881
(-3)
P 		7682
C 13616
(2.6)
P 		11114.3
(1.1)
P 		14183.9
(3)
P 		7371.9
(-1.2)
P 		11773.9
(1.5)
P 		4459
(-3)
P 		9725
avr 13850.4
(3) 		11436.2
(1.1) 		11486.6
(1.1) 		8595.4
(-1.2) 		9248.6
(-0.7) 		6298.8
(-3) 		7552
No Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 4812
1 2 3 4 range
A 5029.3
(3)
P 		3160.9
(0.7)
P 		2897.6
(0.3)
P 		219
(-3)
P 		4810
B 3807.4
(3)
P 		2685.5
(1.1)
P 		2467.9
(0.7)
P 		290.2
(-3)
P 		3517
C 3411.7
(2.7)
P 		3125.6
(2.2)
P 		3590.1
(3)
P 		217.8
(-3)
P 		3372
avr 4082.8
(3) 		2990.7
(1.3) 		2985.2
(1.3) 		242.3
(-3) 		3841

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 3564
1 2 3 4 5 6 range
A 2649.4
(-1)
P 		4321
(3)
P 		1791.6
(-3)
P 		2432
(-1.5)
P 		2738.2
(-0.8)
P 		2083.2
(-2.3)
P 		2529
B 4719.2
(3)
P 		3676.3
(0.5)
P 		2926
(-1.3)
P 		2337.5
(-2.7)
P 		2802.6
(-1.6)
P 		2193
(-3)
P 		2526
C 5046.9
(3)
P 		3391.3
(0.2)
P 		3610.1
(0.6)
P 		1482.5
(-3)
P 		3809.9
(0.9)
P 		1492.7
(-3)
P 		3564
avr 4138.5
(3) 		3796.2
(2.1) 		2775.9
(-0.7) 		2084
(-2.6) 		3116.9
(0.2) 		1923
(-3) 		2216
NetAffx Links Cluster Members
Consensus/Exemplar
Group Members
GeneChip Array Information
Probe Set ID 191926_s_at
GeneChip Array C. elegans Genome Array
Organism Common Name Nematode
Probe Design Information
Transcript ID(Array Design) affy.Ce.1834
Sequence Type Exemplar sequence
Representative Public ID F11C3.3 NCBI
Target Description F11C3.3 /REP_DB=WormBase Gene ID /WP=CE09349 /GEN=unc-54 /TR=O02244 /GB=CAB05505.1 /SUBMIT=HINXTON /CHR=1 /FEA=Sanger Annotation /DEF=myosin heavy chain
Cluster Evidence This cluster is supported by a Sanger Annotation.
Annotation Method Description
Annotation Description This probe set was annotated using the Matching Probes based pipeline to a RefSeq identifier using 1 transcript(s).
Annotation Grade This is a grade A annotation.
Annotation Transcript Cluster (# of Matching Probes) NM_061195(11)
Transcript Assignments
Representative
Transcript		 Description Matching Probes Related Probesets by Grade
NM_061195 NCBI Caenorhabditis elegans UNCoordinated family member (unc-54) (unc-54) mRNA, complete cds. 11/11 None
F11C3.3.1 ENSEMBL cdna:known chromosome:CEL140:I:14860624:14871658:-1 gene:F11C3.3 11/11 None
F11C3.3.3 ENSEMBL cdna:known chromosome:CEL140:I:14863346:14871647:-1 gene:F11C3.3 11/11 None
F11C3.3.4 ENSEMBL cdna:known chromosome:CEL140:I:14863909:14871568:-1 gene:F11C3.3 11/11 None
F11C3.3.2 ENSEMBL cdna:known chromosome:CEL140:I:14863981:14871658:-1 gene:F11C3.3 11/11 None
F11C3.3.5 ENSEMBL cdna:known chromosome:CEL140:I:14864114:14871568:-1 gene:F11C3.3 11/11 None
Annotation Notes
There are no noteworthy cross hybridizing mRNAs found for this probe set.
Genomic Alignment of Consensus/Exemplar Sequence
Assembly Wormbase March 2004
Alignment(s)
Position Identity Coverage Cytoband
chrI:14864229-14871499(-) 100.0 100.0
Public Domain and Genome References
Gene Title myosin heavy chain
Gene Symbol unc-54
Ensembl F11C3.3
Entrez Gene 259839 Entrez gene
SwissProt P02566 EMBL-EBI
WormBase CE09349 Wormbase
Functional Annotations
Ortholog
ID Title Organism
DROSOPHILA_2:1635460_A_AT Myosin heavy chain dm
DROSGENOME1:143263_AT Myosin heavy chain dm
CHICKEN:GGA.5135.1.S1_S_AT myosin, heavy polypeptide 7, cardiac muscle, beta gga
HG-U133A:204737_S_AT myosin, heavy polypeptide 7, cardiac muscle, beta hs
HG-FOCUS:204737_S_AT myosin, heavy polypeptide 7, cardiac muscle, beta hs
HG-U133_PLUS_2:204737_S_AT myosin, heavy polypeptide 7, cardiac muscle, beta hs
HG-U133A_2:204737_S_AT myosin, heavy polypeptide 7, cardiac muscle, beta hs
HG-U133_PLUS_2:216265_X_AT myosin, heavy polypeptide 7, cardiac muscle, beta hs
HG-U133A_2:216265_X_AT myosin, heavy polypeptide 7, cardiac muscle, beta hs
HG-U133A:216265_X_AT myosin, heavy polypeptide 7, cardiac muscle, beta hs
HG-U95AV2:39095_AT myosin, heavy polypeptide 7, cardiac muscle, beta hs
HUGENEFL:Z20656_RNA1_S_AT myosin, heavy polypeptide 7, cardiac muscle, beta hs
HUGENEFL:X52889_AT myosin, heavy polypeptide 7, cardiac muscle, beta hs
HUGENEFL:M21665_S_AT myosin, heavy polypeptide 7, cardiac muscle, beta hs
U133_X3P:G4557772_3P_AT myosin, heavy polypeptide 7, cardiac muscle, beta hs
U133_X3P:HS.929.1.S1_3P_AT myosin, heavy polypeptide 7, cardiac muscle, beta hs
MU11KSUBB:MSA.28941.0_S_AT myosin, heavy polypeptide 7, cardiac muscle, beta mm
MG-U74AV2:98616_F_AT myosin, heavy polypeptide 7, cardiac muscle, beta mm
MOE430A:1448553_AT myosin, heavy polypeptide 7, cardiac muscle, beta mm
MOUSE430A_2:1448553_AT myosin, heavy polypeptide 7, cardiac muscle, beta mm
MOUSE430_2:1448553_AT myosin, heavy polypeptide 7, cardiac muscle, beta mm
MOE430A:1448827_S_AT myosin, heavy polypeptide 7, cardiac muscle, beta mm
MOUSE430A_2:1448827_S_AT myosin, heavy polypeptide 7, cardiac muscle, beta mm
MOUSE430_2:1448827_S_AT myosin, heavy polypeptide 7, cardiac muscle, beta mm
MU11KSUBA:M74752_RC_AT Myosin, heavy polypeptide 7, cardiac muscle, beta (Myh7), mRNA mm
MU11KSUBB:MSA.37917.0_F_AT Myosin, heavy polypeptide 7, cardiac muscle, beta (Myh7), mRNA mm
MOE430B:1458850_AT Myosin, heavy polypeptide 7, cardiac muscle, beta (Myh7), mRNA mm
MOUSE430_2:1458850_AT Myosin, heavy polypeptide 7, cardiac muscle, beta (Myh7), mRNA mm
MU11KSUBB:MSA.33688.0_S_AT Myosin, heavy polypeptide 7, cardiac muscle, beta (Myh7), mRNA mm
RG-U34A:X15939_F_AT myosin, heavy polypeptide 7, cardiac muscle, beta rn
RG-U34A:X15939_I_AT myosin, heavy polypeptide 7, cardiac muscle, beta rn
RG-U34A:X15939_R_AT myosin, heavy polypeptide 7, cardiac muscle, beta rn
RAE230A:1367928_AT myosin, heavy polypeptide 7, cardiac muscle, beta rn
RAT230_2:1367928_AT myosin, heavy polypeptide 7, cardiac muscle, beta rn
RAE230A:1398248_S_AT myosin, heavy polypeptide 7, cardiac muscle, beta rn
RAT230_2:1398248_S_AT myosin, heavy polypeptide 7, cardiac muscle, beta rn
RAE230A:1386993_AT myosin, heavy polypeptide 7, cardiac muscle, beta rn
RAT230_2:1386993_AT myosin, heavy polypeptide 7, cardiac muscle, beta rn
RAE230B:1381787_AT Myosin, heavy polypeptide 7, cardiac muscle, beta rn
RAT230_2:1381787_AT Myosin, heavy polypeptide 7, cardiac muscle, beta rn
RAE230B:1392401_S_AT Myosin, heavy polypeptide 7, cardiac muscle, beta rn
RAT230_2:1392401_S_AT Myosin, heavy polypeptide 7, cardiac muscle, beta rn
Gene Ontology
GO Cellular Component (view graph)
ID Description Evidence Links
16459 myosin inferred from electronic annotation QuickGO AmiGO
GO Molecular Function (view graph)
ID Description Evidence Links
3774 motor activity inferred from electronic annotation QuickGO AmiGO
5524 ATP binding inferred from electronic annotation QuickGO AmiGO
Protein Similarities
Method ID Description E-Value
blast CAB05505 Hypothetical protein F11C3.3 [Caenorhabditis elegans] emb|CAB04089.1| Hypothetical protein F11C3.3 [Caenorhabditis elegans] ref|NP_493596.1| UNCoordinated family member (unc-54) [Caenorhabditis elegans] 0.0
blast AAA28124 myosin heavy chain [Caenorhabditis elegans] sp|P02566|MYO4_CAEEL Myosin-4 (Myosin heavy chain B) (MHC B) (Uncoordinated protein 54) 0.0
blast CAE72546 Hypothetical protein CBG19730 [Caenorhabditis briggsae] 0.0
Protein Domains
Database ID Description E-Value
Pfam IPR004009 EMBL-EBI Myosin N-terminal SH3-like domain 1.0E-22
Pfam IPR001609 EMBL-EBI Myosin head (motor domain) 1.0E-126
Pfam IPR002928 EMBL-EBI Myosin tail 1.0E-126
Sequence
Target Sequence 
>C. ELEGANS:191926_S_AT
tacaaggccgctgaggagcgctccaagaaggctattgctgatgccaccagactcgcagag
gagctccgtcaagaacaagaacactctcagcacgttgaccgtcttcgcaagggacttgag
caacagctcaaggagatccaagtccgtcttgatgaggccgaggctgctgctcttaaggga
ggaaagaaggttatcgccaagctcgaacaacgcgtgcgtgagctcgaatctgaattggac
ggagaacaacgccgcttccaggatgccaacaagaacctcggacgcgccgatagacgtgtt
cgtgagcttcaattccaggttgatgaggacaagaagaacttcgaacgtctccaagatctc
attgacaagctccaacagaagttgaagacccagaagaagcaggttgaggaagctgaggaa
ctcgccaacttgaacctccagaagtacaagcaactcacccaccaacttgaagatgctgag
gagcgcgccgatcaagccgaaaactccctctcaaagatgcgat

BLASTn GenBank NR
Probe Info
Probe Sequence(5'-3') Probe X Probe Y Probe Interrogation
Position 		Strandedness
TACAAGGCCGCTGAGGAGCGCTCCA 641 639 5281 Antisense
GGCTATTGCTGATGCCACCAGACTC 164 539 5310 Antisense
ACAAGAACACTCTCAGCACGTTGAC 568 113 5355 Antisense
TTGACCGTCTTCGCAAGGGACTTGA 569 521 5375 Antisense
GGTTATCGCCAAGCTCGAACAACGC 46 505 5469 Antisense
CGCGTGCGTGAGCTCGAATCTGAAT 488 253 5491 Antisense
GGATGCCAACAAGAACCTCGGACGC 207 511 5541 Antisense
GAACTTCGAACGTCTCCAAGATCTC 208 349 5616 Antisense
GAGGAACTCGCCAACTTGAACCTCC 397 403 5695 Antisense
AACTCACCCACCAACTTGAAGATGC 80 141 5732 Antisense
GAAAACTCCCTCTCAAAGATGCGAT 328 355 5779 Antisense
Sequence Source Affymetrix Proprietary Database