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[191925_at] guanylate cyclase

Description C54E4.3 /REP_DB=WormBase Gene ID /WP=CE16945 /GEN=gcy-37 /TR=O44468 /GB=AAK29797.1 /SUBMIT=ST.LOUIS /CHR=4 /FEA=Sanger Annotation /DEF=guanylate cyclase
Cluster 6grp_total > 25      4grp_total > 37      6grp_cgc > 33      6grp_cgc_sub > De      6grp_total_sub > Decrease      6grp_rule_based > S2      

Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 114
1 2 3 4 range
A 122.5
(3)
P 		98.1
(0.6)
A 		61.4
(-3)
A 		68.9
(-2.3)
M 		61
B 103.3
(3)
A 		87.3
(2)
A 		9
(-3)
A 		96.1
(2.5)
P 		94
C 114.6
(3)
P 		80.4
(-0.4)
A 		54.8
(-3)
A 		63.8
(-2.1)
P 		60
avr 113.5
(3) 		88.6
(0.9) 		41.7
(-3) 		76.3
(-0.1) 		72

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 69
1 2 3 4 5 6 range
A 69.1
(-0)
A 		95.2
(3)
P 		81.9
(1.5)
A 		51.3
(-2.1)
A 		43.4
(-3)
A 		65.7
(-0.4)
A 		52
B 79.3
(3)
M 		78.4
(2.9)
A 		42
(-2.6)
A 		41.6
(-2.7)
A 		49.1
(-1.6)
A 		39.5
(-3)
A 		40
C 108.3
(3)
P 		107.7
(2.9)
M 		100.7
(2.2)
A 		62.1
(-1.6)
A 		60.3
(-1.8)
A 		47.8
(-3)
A 		61
avr 85.6
(1.9) 		93.8
(3) 		74.9
(0.4) 		51.7
(-2.9) 		50.9
(-3) 		51
(-3) 		43
No Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 43
1 2 3 4 range
A 44.6
(3)
P 		21.3
(-1.1)
A 		16.1
(-2)
A 		10.1
(-3)
M 		35
B 32.9
(3)
A 		21.6
(0.8)
A 		2.1
(-3)
A 		20.5
(0.6)
P 		31
C 37.9
(3)
P 		23.1
(-0.3)
A 		19.1
(-1.2)
A 		10.8
(-3)
P 		27
avr 38.5
(3) 		22
(-0.8) 		12.4
(-3) 		13.8
(-2.7) 		26

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 30
1 2 3 4 5 6 range
A 12.7
(-3)
A 		33.9
(3)
P 		17.8
(-1.6)
A 		13
(-2.9)
A 		13.1
(-2.9)
A 		16
(-2.1)
A 		21
B 27.6
(3)
M 		26.1
(2.5)
A 		10.2
(-3)
A 		11
(-2.7)
A 		20
(0.4)
A 		14.7
(-1.4)
A 		17
C 40.1
(3)
P 		32.9
(1.4)
M 		25.6
(-0.2)
A 		12.5
(-3)
A 		19.5
(-1.5)
A 		16
(-2.2)
A 		28
avr 26.8
(1.7) 		31
(3) 		17.9
(-1.2) 		12.2
(-3) 		17.5
(-1.3) 		15.6
(-1.9) 		19
NetAffx Links Cluster Members
Consensus/Exemplar
GeneChip Array Information
Probe Set ID 191925_at
GeneChip Array C. elegans Genome Array
Organism Common Name Nematode
Probe Design Information
Transcript ID(Array Design) affy.Ce.11017
Sequence Type Exemplar sequence
Representative Public ID C54E4.3 NCBI
Target Description C54E4.3 /REP_DB=WormBase Gene ID /WP=CE16945 /GEN=gcy-37 /TR=O44468 /GB=AAK29797.1 /SUBMIT=ST.LOUIS /CHR=4 /FEA=Sanger Annotation /DEF=guanylate cyclase
Cluster Evidence This cluster is supported by a Sanger Annotation.
Annotation Method Description
Annotation Description This probe set was annotated using the Matching Probes based pipeline to a RefSeq identifier using 1 transcript(s).
Annotation Grade This is a grade A annotation.
Annotation Transcript Cluster (# of Matching Probes) NM_067770(11)
Transcript Assignments
Representative
Transcript		 Description Matching Probes Related Probesets by Grade
NM_067770 NCBI Caenorhabditis elegans Guanylyl CYclase family member (gcy-37) (gcy-37) mRNA, complete cds. 11/11 None
C54E4.3 ENSEMBL cdna:known chromosome:CEL140:IV:2150649:2159161:-1 gene:C54E4.3 11/11 None
Annotation Notes
Cross Hybridizing mRNA Matched Probes Nature of Assignment Related Probesets by Grade
GENEFINDER00000038608 8/11 Cross Hyb Matching Probes None
Genomic Alignment of Consensus/Exemplar Sequence
Assembly Wormbase March 2004
Alignment(s)
Position Identity Coverage Cytoband
chrIV:2152343-2158360(-) 96.69 96.69
Public Domain and Genome References
Gene Title guanylate cyclase
Gene Symbol gcy-37
Ensembl C54E4.3
Entrez Gene 191658 Entrez gene
SwissProt Q6DNF3 EMBL-EBI
WormBase CE37494 Wormbase
Functional Annotations
Gene Ontology
GO Biological Process (view graph)
ID Description Evidence Links
7242 intracellular signaling cascade inferred from electronic annotation QuickGO AmiGO
GO Molecular Function (view graph)
ID Description Evidence Links
4383 guanylate cyclase activity inferred from electronic annotation QuickGO AmiGO
Protein Similarities
Method ID Description E-Value
blast AAU87824 Guanylyl cyclase protein 37 [Caenorhabditis elegans] gb|AAT73713.1| guanylate cyclase-like protein [Caenorhabditis elegans] ref|NP_500171.2| Guanylyl CYclase family member (gcy-37) [Caenorhabditis elegans] sp|Q6DNF3|GCY37_CAEEL Soluble guanylate cyclase gcy-37 0.0
blast CAE68208 Hypothetical protein CBG13876 [Caenorhabditis briggsae] 0.0
blast CAB03288 Hypothetical protein T04D3.4 [Caenorhabditis elegans] gb|AAT73711.1| guanylate cyclase-like protein [Caenorhabditis elegans] ref|NP_493344.2| Guanylyl CYclase family member (gcy-35) [Caenorhabditis elegans] sp|O02298|GCY35_CAEEL Soluble guanylate cyclase gcy-35 1.0E-132
Protein Domains
Database ID Description E-Value
Pfam IPR001054 EMBL-EBI Guanylate cyclase 3.0E-43
Sequence
Target Sequence 
>C. ELEGANS:191925_AT
aaaaatcgcagaccgacaggctcctcttcgagtttgtgccgcccgtgattgccgaggctc
tgcgagccgcaaaaactgtcccagcactaatgcaaaaacgaatcagtattgatttttcag
aagaattctccgattgttccgtgatattcacagatatcccagactttttcacaatcagcg
taaattgctcaccaacagaaatcatcacagtggtcactgatctcttccacagatttgaca
gaataatcgaaaagcacaagggatacaaggtgctgtctctgatggacagttacctgattg
tcggcggtgttccaaatgctaatcaatatcactgcgaagattctttgaatcttgctctcg
gacttttattcgaggctaaacaggtcgtggtgccgaaattggagcgaagtgttcggctga
gaattggtgtgcattgtgggcctgttgttgctggaattgttagtcagcaaaagccaagat
tctgcgtcctcggcaacactgtaaacgtcactaaatcaatctgctcacacagttcacct

BLASTn GenBank NR
Probe Info
Probe Sequence(5'-3') Probe X Probe Y Probe Interrogation
Position 		Strandedness
AAAAATCGCAGACCGACAGGCTCCT 483 129 1190 Antisense
TCTGCGAGCCGCAAAAACTGTCCCA 706 609 1248 Antisense
ATTCTCCGATTGTTCCGTGATATTC 364 11 1314 Antisense
ATCCCAGACTTTTTCACAATCAGCG 141 39 1345 Antisense
ACAGTGGTCACTGATCTCTTCCACA 654 107 1396 Antisense
GATTGTCGGCGGTGTTCCAAATGCT 425 435 1485 Antisense
ATTCTTTGAATCTTGCTCTCGGACT 502 11 1529 Antisense
CATTGTGGGCCTGTTGTTGCTGGAA 708 217 1621 Antisense
CAAAAGCCAAGATTCTGCGTCCTCG 665 189 1657 Antisense
CGTCCTCGGCAACACTGTAAACGTC 316 243 1674 Antisense
ATCAATCTGCTCACACAGTTCACCT 232 27 1704 Antisense
Sequence Source Affymetrix Proprietary Database