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[191920_at] thrombospondin like

Description F25H8.3 /REP_DB=WormBase Gene ID /WP=CE05729 /GEN=gon-1 /TR=Q19791 /GB=CAA93287.1 /SUBMIT=HINXTON /CHR=4 /FEA=Sanger Annotation /DEF=thrombospondin like
Cluster 6grp_total > 01      4grp_total > 32      6grp_cgc > 64      

Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 43
1 2 3 4 range
A 4.5
(-1.4)
A
2.7
(-3)
A
7.4
(1.3)
A
9.3
(3)
A
7
B 4.4
(-2.7)
A
8.8
(-2.1)
A
45.7
(3)
A
2.3
(-3)
A
43
C 6.9
(-2.4)
A
3.5
(-3)
A
30.3
(1.9)
A
36
(3)
A
33
avr 5.3
(-2.9)
5
(-3)
27.8
(3)
15.9
(-0.1)
23

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 32
1 2 3 4 5 6 range
A 4.3
(-1.5)
A
3.6
(-2.1)
A
4.8
(-1.1)
A
3.1
(-2.5)
A
10.1
(3)
A
2.4
(-3)
A
8
B 5.3
(-2.9)
A
11.1
(-0.6)
A
5.1
(-3)
A
19.9
(3)
A
19
(2.6)
A
5.4
(-2.9)
A
15
C 3.3
(-2.7)
A
34
(3)
A
8.9
(-1.6)
A
8.6
(-1.7)
A
4.4
(-2.5)
A
1.6
(-3)
A
32
avr 4.3
(-2.5)
16.2
(3)
6.3
(-1.5)
10.5
(0.4)
11.2
(0.7)
3.1
(-3)
13
No Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 10
1 2 3 4 range
A 1.6
(1.6)
A
0.6
(-3)
A
1.9
(3)
A
1.4
(0.7)
A
1
B 1.4
(-2.5)
A
2.2
(-2)
A
10.6
(3)
A
0.5
(-3)
A
10
C 2.3
(-2.2)
A
1
(-3)
A
10.5
(3)
A
6.1
(0.2)
A
10
avr 1.8
(-2.5)
1.3
(-3)
7.7
(3)
2.7
(-1.7)
6

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 10
1 2 3 4 5 6 range
A 0.8
(-2.5)
A
1.3
(-1.3)
A
1
(-2)
A
0.8
(-2.5)
A
3
(3)
A
0.6
(-3)
A
2
B 1.8
(-2.4)
A
3.7
(-0.7)
A
1.2
(-3)
A
5.3
(0.8)
A
7.7
(3)
A
2
(-2.3)
A
7
C 1.2
(-2.6)
A
10.4
(3)
A
2.3
(-1.9)
A
1.7
(-2.3)
A
1.4
(-2.5)
A
0.5
(-3)
A
10
avr 1.3
(-2.6)
5.1
(3)
1.5
(-2.3)
2.6
(-0.7)
4
(1.4)
1
(-3)
4
NetAffx Links Cluster Members
Consensus/Exemplar
GeneChip Array Information
Probe Set ID 191920_at
GeneChip Array C. elegans Genome Array
Organism Common Name Nematode
Probe Design Information
Transcript ID(Array Design) affy.Ce.9932
Sequence Type Exemplar sequence
Representative Public ID F25H8.3 NCBI
Target Description F25H8.3 /REP_DB=WormBase Gene ID /WP=CE05729 /GEN=gon-1 /TR=Q19791 /GB=CAA93287.1 /SUBMIT=HINXTON /CHR=4 /FEA=Sanger Annotation /DEF=thrombospondin like
Cluster Evidence This cluster is supported by a Sanger Annotation.
Annotation Method Description
Annotation Description This probe set was annotated using the Matching Probes based pipeline to a RefSeq identifier using 1 transcript(s).
Annotation Grade This is a grade A annotation.
Annotation Transcript Cluster (# of Matching Probes) NM_069391(11)
Transcript Assignments
Representative
Transcript
Description Matching Probes Related Probesets by Grade
NM_069391 NCBI Caenorhabditis elegans abnormal GONad development family member (gon-1) (gon-1) mRNA, complete cds. 11/11 None
SNAP00000013892 ENSEMBL cdna:SNAP chromosome:CEL140:IV:9935039:9937874:-1 11/11 None
GENEFINDER00000013896 ENSEMBL cdna:GeneFinder chromosome:CEL140:IV:9934275:9937412:-1 11/11 None
F25H8.3 ENSEMBL cdna:known chromosome:CEL140:IV:9935039:9945747:-1 gene:F25H8.3 11/11 None
Annotation Notes
There are no noteworthy cross hybridizing mRNAs found for this probe set.
Genomic Alignment of Consensus/Exemplar Sequence
Assembly Wormbase March 2004
Alignment(s)
Position Identity Coverage Cytoband
chrIV:9935044-9945753(-) 100.0 100.0
Public Domain and Genome References
Gene Title thrombospondin like
Gene Symbol gon-1
Ensembl F25H8.3
Entrez Gene 177850 Entrez gene
SwissProt Q19791 EMBL-EBI
WormBase CE05729 Wormbase
Functional Annotations
Ortholog
ID Title Organism
CANINE_2:CFAAFFX.11102.1.S1_AT similar to a disintegrin and metalloproteinase with thrombospondin motifs 9 preproprotein cfa
CANINE_2:CFAAFFX.11106.1.S1_S_AT similar to a disintegrin and metalloproteinase with thrombospondin motifs 9 preproprotein cfa
CHICKEN:GGAAFFX.22212.1.S1_AT similar to a disintegrin and metalloproteinase with thrombospondin motifs 9 isoform 1 preproprotein gga
CHICKEN:GGAAFFX.22234.2.S1_AT similar to a disintegrin and metalloproteinase with thrombospondin motifs 9 isoform 1 preproprotein gga
CHICKEN:GGAAFFX.22234.3.S1_S_AT similar to a disintegrin and metalloproteinase with thrombospondin motifs 9 isoform 1 preproprotein gga
CHICKEN:GGAAFFX.4600.2.S1_AT similar to a disintegrin and metalloproteinase with thrombospondin motifs 9 isoform 1 preproprotein gga
CHICKEN:GGAAFFX.4600.2.S1_S_AT similar to a disintegrin and metalloproteinase with thrombospondin motifs 9 isoform 1 preproprotein gga
CHICKEN:GGAAFFX.4600.5.S1_S_AT similar to a disintegrin and metalloproteinase with thrombospondin motifs 9 isoform 1 preproprotein gga
HG-U133_PLUS_2:226814_AT ADAM metallopeptidase with thrombospondin type 1 motif, 9 hs
HG-U133B:226814_AT ADAM metallopeptidase with thrombospondin type 1 motif, 9 hs
HG-U133_PLUS_2:233785_AT ADAM metallopeptidase with thrombospondin type 1 motif, 9 hs
HG-U133B:233785_AT ADAM metallopeptidase with thrombospondin type 1 motif, 9 hs
HG-U133_PLUS_2:220287_AT ADAM metallopeptidase with thrombospondin type 1 motif, 9 hs
HG-U133A:220287_AT ADAM metallopeptidase with thrombospondin type 1 motif, 9 hs
HG-FOCUS:220287_AT ADAM metallopeptidase with thrombospondin type 1 motif, 9 hs
HG-U133A_2:220287_AT ADAM metallopeptidase with thrombospondin type 1 motif, 9 hs
HU35KSUBA:RC_AA478778_AT ADAM metallopeptidase with thrombospondin type 1 motif, 9 hs
U133_X3P:G9910121_3P_AT ADAM metallopeptidase with thrombospondin type 1 motif, 9 hs
U133_X3P:HS2.126855.2.S1_3P_X_AT ADAM metallopeptidase with thrombospondin type 1 motif, 9 hs
U133_X3P:HS2.126855.2.S1_3P_AT ADAM metallopeptidase with thrombospondin type 1 motif, 9 hs
U133_X3P:HS.16450.0.A1_3P_AT ADAM metallopeptidase with thrombospondin type 1 motif, 9 hs
U133_X3P:HS.126855.1.S1_3P_AT ADAM metallopeptidase with thrombospondin type 1 motif, 9 hs
HG-U133_PLUS_2:1554697_AT ADAM metallopeptidase with thrombospondin type 1 motif, 9 hs
HG-U95C:65457_AT ADAM metallopeptidase with thrombospondin type 1 motif, 9 hs
HG-U133_PLUS_2:233928_AT ADAM metallopeptidase with thrombospondin type 1 motif, 9 hs
HG-U133B:233928_AT ADAM metallopeptidase with thrombospondin type 1 motif, 9 hs
U133_X3P:HS2.384621.1.S1_3P_AT ADAM metallopeptidase with thrombospondin type 1 motif, 9 hs
U133_X3P:HS2.196245.1.A1_3P_S_AT ADAM metallopeptidase with thrombospondin type 1 motif, 9 hs
U133_X3P:HS.127811.0.A1_3P_AT ADAM metallopeptidase with thrombospondin type 1 motif, 9 hs
U133_X3P:HS.126855.1.A1_3P_AT ADAM metallopeptidase with thrombospondin type 1 motif, 9 hs
HG-U133_PLUS_2:1556413_A_AT ADAM metallopeptidase with thrombospondin type 1 motif, 9 hs
HG-U133_PLUS_2:1556989_AT ADAM metallopeptidase with thrombospondin type 1 motif, 9 hs
HG-U133_PLUS_2:241369_AT ADAM metallopeptidase with thrombospondin type 1 motif, 9 hs
HG-U133B:241369_AT ADAM metallopeptidase with thrombospondin type 1 motif, 9 hs
HG-U95E:69228_AT ADAM metallopeptidase with thrombospondin type 1 motif, 9 hs
HG-U95D:70960_AT ADAM metallopeptidase with thrombospondin type 1 motif, 9 hs
HG-U95E:74066_AT ADAM metallopeptidase with thrombospondin type 1 motif, 9 hs
HG-U95E:81951_AT ADAM metallopeptidase with thrombospondin type 1 motif, 9 hs
HG-U95D:89207_AT ADAM metallopeptidase with thrombospondin type 1 motif, 9 hs
RAE230A:1376481_AT A disintegrin-like and metalloprotease (reprolysin type) with thrombospondin type 1 motif, 9 (predicted) rn
RAT230_2:1376481_AT A disintegrin-like and metalloprotease (reprolysin type) with thrombospondin type 1 motif, 9 (predicted) rn
RAE230B:1392073_AT A disintegrin-like and metalloprotease (reprolysin type) with thrombospondin type 1 motif, 9 (predicted) rn
RAT230_2:1392073_AT A disintegrin-like and metalloprotease (reprolysin type) with thrombospondin type 1 motif, 9 (predicted) rn
RAE230B:1394518_AT A disintegrin-like and metalloprotease (reprolysin type) with thrombospondin type 1 motif, 9 (predicted) rn
RAT230_2:1394518_AT A disintegrin-like and metalloprotease (reprolysin type) with thrombospondin type 1 motif, 9 (predicted) rn
RG-U34B:RC_AA923996_AT A disintegrin-like and metalloprotease (reprolysin type) with thrombospondin type 1 motif, 9 (predicted) rn
Gene Ontology
GO Biological Process (view graph)
ID Description Evidence Links
6508 proteolysis inferred from electronic annotation QuickGO AmiGO
GO Cellular Component (view graph)
ID Description Evidence Links
5623 cell inferred from direct assay QuickGO AmiGO
GO Molecular Function (view graph)
ID Description Evidence Links
4222 metalloendopeptidase activity inferred from electronic annotation QuickGO AmiGO
8237 metallopeptidase activity inferred from electronic annotation QuickGO AmiGO
8270 zinc ion binding inferred from electronic annotation QuickGO AmiGO
8237 metallopeptidase activity inferred from direct assay QuickGO AmiGO
Protein Similarities
Method ID Description E-Value
blast CAA93288 Hypothetical protein F25H8.3 [Caenorhabditis elegans] emb|CAA93287.1| Hypothetical protein F25H8.3 [Caenorhabditis elegans] ref|NP_501792.1| abnormal GONad development family member (gon-1) [Caenorhabditis elegans] 0.0
blast CAE59959 Hypothetical protein CBG03449 [Caenorhabditis briggsae] 0.0
blast XP_848393 PREDICTED: similar to a disintegrin and metalloproteinase with thrombospondin motifs 9 preproprotein [Canis familiaris] 0.0
Protein Domains
Database ID Description E-Value
Pfam IPR010294 EMBL-EBI ADAM-TS Spacer 1 7.0E-54
Pfam IPR001590 EMBL-EBI Peptidase M12B, ADAM/reprolysin 3.2E-11
Pfam IPR000884 EMBL-EBI Thrombospondin, type I 2.0E-10
Pfam IPR000884 EMBL-EBI Thrombospondin, type I 1.7E-7
Pfam IPR000884 EMBL-EBI Thrombospondin, type I 1.0E-6
Pfam IPR000884 EMBL-EBI Thrombospondin, type I 3.9E-5
Trans Membrane
ID Number Of Domains Domain Boundaries
NP_501792.1 1 7-29
F25H8.3 1 7-29
GENEFINDER00000013896 2 527-544,565-587
Sequence
Target Sequence
>C. ELEGANS:191920_AT
acactattcttcttgacggattcactattgaaatttattgtcatcgaatgaattcaacca
ttcctaaagcttatttgaacgttaatccaagaaccaattttgcagaggtttatggaaaaa
aattaatataccctcatacttgcccatttaatggtgatcgtaatgattcatgccattgtt
cagaagacggcgatgcaagtgctggattgacgagattcaataaagttcgaatagatttgt
tgaatagaaagttccatctggcggattatacatttgcaaaacgagaatatggtgttcatg
tgccatatggtactgccggtgattgctacagtatgaaagattgtccacagggaatattct
caattgatttaaaatctgctggtctgaaattagttgacgatctgaattgggaggatcaag
gtcatcgaacatcctctcgaatcgatcgtttttataacaatgcaaaagttattggtcact
gtggtggtttttgtggaaaatgctctcctgagcggtaca


BLASTn GenBank NR
Probe Info
Probe Sequence(5'-3') Probe X Probe Y Probe Interrogation
Position
Strandedness
ACACTATTCTTCTTGACGGATTCAC 124 111 5885 Antisense
AATTCAACCATTCCTAAAGCTTATT 483 173 5935 Antisense
ATTAATATACCCTCATACTTGCCCA 48 13 6006 Antisense
GATTCATGCCATTGTTCAGAAGACG 145 431 6049 Antisense
AGAAGACGGCGATGCAAGTGCTGGA 498 73 6066 Antisense
GAAAGTTCCATCTGGCGGATTATAC 342 359 6131 Antisense
GTTCATGTGCCATATGGTACTGCCG 431 441 6178 Antisense
ATGGTACTGCCGGTGATTGCTACAG 432 51 6191 Antisense
GATCAAGGTCATCGAACATCCTCTC 491 421 6298 Antisense
GAACATCCTCTCGAATCGATCGTTT 621 351 6311 Antisense
GGAAAATGCTCTCCTGAGCGGTACA 288 529 6379 Antisense
Sequence Source Affymetrix Proprietary Database