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[191913_s_at] protein-tyrosine phosphatase

Description C17H12.3 /REP_DB=WormBase Gene ID /WP=CE16864 /TR=O45085 /GB=AAC02582.1 /SUBMIT=ST.LOUIS /CHR=4 /FEA=Sanger Annotation /DEF=protein-tyrosine phosphatase
Cluster 6grp_high1_10_10 > 87      4grp_high_8_8 > 29      6grp_total > 87      4grp_total > 17      6grp_high1_sub > In      6grp_total_sub > Increase      6grp_rule_based > S6      

Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 113
1 2 3 4 range
A 80
(-3)
P 		83.3
(-2.8)
P 		94.3
(-2)
P 		162.2
(3)
A 		82
B 74.1
(3)
P 		53.9
(-3)
A 		57
(-2.1)
A 		69.4
(1.6)
P 		20
C 48.9
(-3)
M 		115.7
(1.9)
P 		82.7
(-0.5)
P 		131.4
(3)
P 		83
avr 67.7
(-3) 		84.3
(-1.1) 		78
(-1.8) 		121
(3) 		53

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 236
1 2 3 4 5 6 range
A 52
(-3)
A 		65
(-2.7)
P 		62
(-2.7)
P 		68.5
(-2.6)
A 		136.9
(-0.8)
P 		288
(3)
P 		236
B 71.6
(-2.9)
P 		68.9
(-3)
A 		100.8
(-1.8)
P 		92.4
(-2.2)
P 		151.4
(-0)
P 		235
(3)
P 		166
C 61.8
(-2.9)
A 		92.9
(-1.9)
P 		60.1
(-3)
A 		60.5
(-3)
P 		146.2
(-0.1)
P 		237.6
(3)
P 		178
avr 61.8
(-3) 		75.6
(-2.6) 		74.3
(-2.6) 		73.8
(-2.6) 		144.8
(-0.4) 		253.5
(3) 		192
No Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 20
1 2 3 4 range
A 29.1
(3)
P 		18.1
(-3)
P 		24.7
(0.6)
P 		23.7
(0.1)
A 		11
B 23.6
(3)
P 		13.3
(-2.9)
A 		13.2
(-3)
A 		14.8
(-2.1)
P 		10
C 16.2
(-3)
M 		33.3
(3)
P 		28.8
(1.4)
P 		22.2
(-0.9)
P 		17
avr 23
(3) 		21.6
(0) 		22.2
(1.3) 		20.2
(-3) 		3

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 78
1 2 3 4 5 6 range
A 9.6
(-3)
A 		23.1
(-1.7)
P 		13.5
(-2.6)
P 		17.4
(-2.2)
A 		41.3
(0.1)
P 		70.1
(3)
P 		61
B 24.9
(-2.8)
P 		22.9
(-3)
A 		24.5
(-2.9)
P 		24.5
(-2.9)
P 		61.5
(0.6)
P 		87.6
(3)
P 		65
C 22.9
(-2)
A 		28.3
(-1.6)
P 		15.3
(-2.7)
A 		12.2
(-3)
P 		47.3
(0.1)
P 		79.5
(3)
P 		67
avr 19.1
(-2.9) 		24.8
(-2.3) 		17.8
(-3) 		18
(-3) 		50
(0.2) 		79.1
(3) 		61
NetAffx Links Cluster Members
Consensus/Exemplar
Group Members
GeneChip Array Information
Probe Set ID 191913_s_at
GeneChip Array C. elegans Genome Array
Organism Common Name Nematode
Probe Design Information
Transcript ID(Array Design) affy.Ce.9209
Sequence Type Exemplar sequence
Representative Public ID C17H12.3 NCBI
Target Description C17H12.3 /REP_DB=WormBase Gene ID /WP=CE16864 /TR=O45085 /GB=AAC02582.1 /SUBMIT=ST.LOUIS /CHR=4 /FEA=Sanger Annotation /DEF=protein-tyrosine phosphatase
Cluster Evidence This cluster is supported by a Sanger Annotation.
Annotation Method Description
Annotation Description This probe set was annotated using the Matching Probes based pipeline to a RefSeq identifier using 1 transcript(s).
Annotation Grade This is a grade A annotation.
Annotation Transcript Cluster (# of Matching Probes) NM_068640(11)
Transcript Assignments
Representative
Transcript		 Description Matching Probes Related Probesets by Grade
NM_068640 NCBI Caenorhabditis elegans C17H12.3 (C17H12.3) mRNA, complete cds. 11/11 None
SNAP00000015107 ENSEMBL cdna:SNAP chromosome:CEL140:IV:6793944:6795166:-1 11/11 None
GENEFINDER00000015127 ENSEMBL cdna:GeneFinder chromosome:CEL140:IV:6793944:6795166:-1 11/11 None
C17H12.3 ENSEMBL cdna:known chromosome:CEL140:IV:6793918:6795172:-1 gene:C17H12.3 11/11 None
Annotation Notes
There are no noteworthy cross hybridizing mRNAs found for this probe set.
Genomic Alignment of Consensus/Exemplar Sequence
Assembly Wormbase March 2004
Alignment(s)
Position Identity Coverage Cytoband
chrIV:6793949-6795169(-) 100.0 100.0
Public Domain and Genome References
Gene Title protein-tyrosine phosphatase
Ensembl C17H12.3
Entrez Gene 177443 Entrez gene
SwissProt O45085 EMBL-EBI
WormBase CE16864 Wormbase
Functional Annotations
Gene Ontology
GO Biological Process (view graph)
ID Description Evidence Links
6470 protein amino acid dephosphorylation inferred from electronic annotation QuickGO AmiGO
GO Molecular Function (view graph)
ID Description Evidence Links
4721 phosphoprotein phosphatase activity inferred from electronic annotation QuickGO AmiGO
4725 protein tyrosine phosphatase activity inferred from electronic annotation QuickGO AmiGO
Protein Similarities
Method ID Description E-Value
blast AAC02582 Hypothetical protein C17H12.3 [Caenorhabditis elegans] ref|NP_501041.1| C17H12.3 [Caenorhabditis elegans] 0.0
blast CAE61477 Hypothetical protein CBG05371 [Caenorhabditis briggsae] 0.0
blast CAE67632 Hypothetical protein CBG13187 [Caenorhabditis briggsae] 1.0E-157
Protein Domains
Database ID Description E-Value
Pfam IPR000242 EMBL-EBI Tyrosine specific protein phosphatase 8.3E-95
Pfam IPR000242 EMBL-EBI Tyrosine specific protein phosphatase 8.3E-95
Sequence
Target Sequence 
>C. ELEGANS:191913_S_AT
tgtgcacagtactggccattggcaatgggagagaagaaagaagtgaagggaggaattgtg
gtggagaatgtatctggaacaaaaccgatggacagagacgctgaaattcagattacaact
ttgcaagtgtcatttggagaccagaagatgtctgttcgtcatcttcattggagtgactgg
cctgatcgtggtgtgccaccgtgcaaacttacaagtctggagcttctgtcagctgtccgt
ggatcacgtgtaccgattgtcgtgcattgttcggctggcatcggtagaactggaaccatt
gttgcgatcgagtacattttggaaagaatcgccgagaataagcaatgcccaccaatgccg
gatcttgtgaagtcgcttcgtgatcaacgtgcctattcgatccagacggacatgcaatat
ctctacattcaccgggtcatgtt

BLASTn GenBank NR
Probe Info
Probe Sequence(5'-3') Probe X Probe Y Probe Interrogation
Position 		Strandedness
TGTGCACAGTACTGGCCATTGGCAA 255 557 583 Antisense
TCTGTTCGTCATCTTCATTGGAGTG 490 607 733 Antisense
TGACTGGCCTGATCGTGGTGTGCCA 338 569 756 Antisense
TGGTGTGCCACCGTGCAAACTTACA 703 551 771 Antisense
AAGTCTGGAGCTTCTGTCAGCTGTC 122 159 795 Antisense
GCTGTCCGTGGATCACGTGTACCGA 678 293 814 Antisense
CGATTGTCGTGCATTGTTCGGCTGG 679 247 836 Antisense
GAATAAGCAATGCCCACCAATGCCG 277 327 918 Antisense
GAAGTCGCTTCGTGATCAACGTGCC 122 337 951 Antisense
CAACGTGCCTATTCGATCCAGACGG 317 187 967 Antisense
ATCTCTACATTCACCGGGTCATGTT 105 33 1001 Antisense
Sequence Source Affymetrix Proprietary Database