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[191910_at] Amidophosphoribosyltransferase

Description T04A8.5 /REP_DB=WormBase Gene ID /WP=CE01074 /TR=Q22134 /GB=CAA84723.1 /SUBMIT=HINXTON /CHR=3 /FEA=Sanger Annotation /DEF=Amidophosphoribosyltransferase
Cluster 6grp_highest_10_10 > 57      6grp_high1_10_10 > 74      4grp_highest_8_8 > 22      4grp_high_8_8 > 14      6grp_highest_nonorm > 82      6grp_total > 64      4grp_total > 09      4grp_rule_based > L4      

Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 1597
1 2 3 4 range
A 110
(-3)
P 		164
(-2.8)
P 		243
(-2.4)
P 		1463.1
(3)
P 		1353
B 73.4
(-3)
P 		134.2
(-2.8)
P 		208.6
(-2.5)
P 		1670.1
(3)
P 		1597
C 116.1
(-3)
P 		160.2
(-2.8)
P 		282
(-2.3)
P 		1465.9
(3)
P 		1350
avr 99.8
(-3) 		152.8
(-2.8) 		244.5
(-2.4) 		1533
(3) 		1433

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 591
1 2 3 4 5 6 range
A 88.5
(-3)
P 		462.4
(1.4)
P 		589
(2.9)
P 		413.5
(0.8)
P 		324.1
(-0.2)
P 		598.2
(3)
P 		510
B 92.7
(-3)
P 		328.3
(-0.4)
P 		643.7
(3)
P 		357.1
(-0.1)
P 		283.6
(-0.9)
P 		596.8
(2.5)
P 		551
C 140.1
(-3)
P 		325.4
(-0.9)
P 		679.6
(3)
P 		356.7
(-0.6)
P 		284.8
(-1.4)
P 		651.3
(2.7)
P 		540
avr 107.1
(-3) 		372
(-0) 		637.4
(3) 		375.8
(0) 		297.5
(-0.8) 		615.4
(2.8) 		530
No Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 333
1 2 3 4 range
A 40.1
(-2.8)
P 		35.6
(-3)
P 		63.5
(-2.1)
P 		214.2
(3)
P 		179
B 23.4
(-3)
P 		33.1
(-2.8)
P 		48.3
(-2.6)
P 		355.9
(3)
P 		333
C 38.4
(-3)
P 		46.1
(-2.8)
P 		98.3
(-1.3)
P 		247.2
(3)
P 		209
avr 34
(-3) 		38.3
(-2.9) 		70
(-2.1) 		272.4
(3) 		238

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 206
1 2 3 4 5 6 range
A 16.3
(-3)
P 		164.5
(3)
P 		128.3
(1.5)
P 		104.9
(0.6)
P 		97.8
(0.3)
P 		145.6
(2.2)
P 		148
B 32.3
(-3)
P 		109.3
(-0.6)
P 		156.3
(0.9)
P 		94.6
(-1)
P 		115.2
(-0.4)
P 		222.5
(3)
P 		190
C 51.9
(-3)
P 		99.3
(-1.3)
P 		173
(1.4)
P 		71.7
(-2.3)
P 		92.1
(-1.5)
P 		218
(3)
P 		166
avr 33.5
(-3) 		124.4
(0.4) 		152.5
(1.4) 		90.4
(-0.9) 		101.7
(-0.5) 		195.4
(3) 		162
NetAffx Links Cluster Members
Consensus/Exemplar
GeneChip Array Information
Probe Set ID 191910_at
GeneChip Array C. elegans Genome Array
Organism Common Name Nematode
Probe Design Information
Transcript ID(Array Design) affy.Ce.6280
Sequence Type Exemplar sequence
Representative Public ID T04A8.5 NCBI
Target Description T04A8.5 /REP_DB=WormBase Gene ID /WP=CE01074 /TR=Q22134 /GB=CAA84723.1 /SUBMIT=HINXTON /CHR=3 /FEA=Sanger Annotation /DEF=Amidophosphoribosyltransferase
Cluster Evidence This cluster is supported by a Sanger Annotation.
Annotation Method Description
Annotation Description This probe set was annotated using the Matching Probes based pipeline to a RefSeq identifier using 1 transcript(s).
Annotation Grade This is a grade A annotation.
Annotation Transcript Cluster (# of Matching Probes) NM_065557(11)
Transcript Assignments
Representative
Transcript		 Description Matching Probes Related Probesets by Grade
NM_065557 NCBI Caenorhabditis elegans T04A8.5 (Amidophosphoribosyltransferase) mRNA, complete cds. 11/11 None
GENEFINDER00000041115 ENSEMBL cdna:GeneFinder chromosome:CEL140:III:4689308:4692041:1 11/11 None
SNAP00000041092 ENSEMBL cdna:SNAP chromosome:CEL140:III:4689648:4692041:1 11/11 None
T04A8.5 ENSEMBL cdna:known chromosome:CEL140:III:4689270:4692085:1 gene:T04A8.5 11/11 None
Annotation Notes
There are no noteworthy cross hybridizing mRNAs found for this probe set.
Genomic Alignment of Consensus/Exemplar Sequence
Assembly Wormbase March 2004
Alignment(s)
Position Identity Coverage Cytoband
chrIII:4689307-4692041(+) 100.0 100.0
Public Domain and Genome References
Gene Title Amidophosphoribosyltransferase
Ensembl T04A8.5
Entrez Gene 175613 Entrez gene
SwissProt Q22134 EMBL-EBI
WormBase CE01074 Wormbase
Functional Annotations
Ortholog
ID Title Organism
ATGENOME1:16086_S_AT amidophosphoribosyltransferase / glutamine phosphoribosylpyrophosphate amidotransferase / phosphoribosyldiphosphate 5-amidotransferase at
ATH1-121501:263239_AT amidophosphoribosyltransferase / glutamine phosphoribosylpyrophosphate amidotransferase / phosphoribosyldiphosphate 5-amidotransferase at
CANINE_2:CFAAFFX.4220.1.S1_AT similar to phosphoribosyl pyrophosphate amidotransferase proprotein cfa
DROSOPHILA_2:1627868_AT Phosphoribosylamidotransferase dm
DROSGENOME1:154976_AT Phosphoribosylamidotransferase dm
CHICKEN:GGA.17731.1.S1_S_AT phosphoribosyl pyrophosphate amidotransferase gga
CHICKEN:GGA.2870.1.S1_AT phosphoribosyl pyrophosphate amidotransferase gga
HG-U133A:209434_S_AT phosphoribosyl pyrophosphate amidotransferase hs
HG-U133_PLUS_2:209434_S_AT phosphoribosyl pyrophosphate amidotransferase hs
HG-U133A_2:209434_S_AT phosphoribosyl pyrophosphate amidotransferase hs
HU35KSUBD:RC_AA442070_S_AT phosphoribosyl pyrophosphate amidotransferase hs
HUGENEFL:U00238_RNA1_AT phosphoribosyl pyrophosphate amidotransferase hs
U133_X3P:G404860_3P_A_AT phosphoribosyl pyrophosphate amidotransferase hs
U133_X3P:HS.311.1.A1_3P_A_AT phosphoribosyl pyrophosphate amidotransferase hs
HG-U133A_2:209433_S_AT phosphoribosyl pyrophosphate amidotransferase hs
HG-FOCUS:209433_S_AT phosphoribosyl pyrophosphate amidotransferase hs
HG-U133_PLUS_2:209433_S_AT phosphoribosyl pyrophosphate amidotransferase hs
HG-U133A:209433_S_AT phosphoribosyl pyrophosphate amidotransferase hs
HG-U95AV2:34341_AT phosphoribosyl pyrophosphate amidotransferase hs
HG-U133_PLUS_2:244505_AT Phosphoribosyl pyrophosphate amidotransferase hs
HG-U133B:244505_AT Phosphoribosyl pyrophosphate amidotransferase hs
HG-U95E:75427_AT Phosphoribosyl pyrophosphate amidotransferase hs
U133_X3P:HS.311625.0.A1_3P_AT Phosphoribosyl pyrophosphate amidotransferase hs
MG-U74AV2:95553_AT phosphoribosyl pyrophosphate amidotransferase mm
MG-U74AV2:95554_AT phosphoribosyl pyrophosphate amidotransferase mm
MG-U74CV2:168502_R_AT phosphoribosyl pyrophosphate amidotransferase mm
MOE430A:1428543_AT phosphoribosyl pyrophosphate amidotransferase mm
MOUSE430A_2:1428543_AT phosphoribosyl pyrophosphate amidotransferase mm
MOUSE430_2:1428543_AT phosphoribosyl pyrophosphate amidotransferase mm
MOE430A:1452831_S_AT phosphoribosyl pyrophosphate amidotransferase mm
MOUSE430A_2:1452831_S_AT phosphoribosyl pyrophosphate amidotransferase mm
MOUSE430_2:1452831_S_AT phosphoribosyl pyrophosphate amidotransferase mm
MOE430B:1441770_AT phosphoribosyl pyrophosphate amidotransferase mm
MOUSE430_2:1441770_AT phosphoribosyl pyrophosphate amidotransferase mm
MU19KSUBB:TC32638_AT Phosphoribosyl pyrophosphate amidotransferase, mRNA (cDNA clone MGC:38417 IMAGE:5346105) mm
MU19KSUBC:TC38475_S_AT Phosphoribosyl pyrophosphate amidotransferase, mRNA (cDNA clone MGC:38417 IMAGE:5346105) mm
MU11KSUBB:W13242_S_AT Phosphoribosyl pyrophosphate amidotransferase, mRNA (cDNA clone MGC:38417 IMAGE:5346105) mm
RG-U34A:D10853_AT phosphoribosyl pyrophosphate amidotransferase rn
RG-U34B:RC_AI043695_AT phosphoribosyl pyrophosphate amidotransferase rn
RAE230A:1369785_AT phosphoribosyl pyrophosphate amidotransferase rn
RAT230_2:1369785_AT phosphoribosyl pyrophosphate amidotransferase rn
Gene Ontology
GO Biological Process (view graph)
ID Description Evidence Links
8152 metabolism inferred from electronic annotation QuickGO AmiGO
9113 purine base biosynthesis inferred from electronic annotation QuickGO AmiGO
9116 nucleoside metabolism inferred from electronic annotation QuickGO AmiGO
GO Molecular Function (view graph)
ID Description Evidence Links
4044 amidophosphoribosyltransferase activity inferred from electronic annotation QuickGO AmiGO
16740 transferase activity inferred from electronic annotation QuickGO AmiGO
Protein Similarities
Method ID Description E-Value
blast CAA84723 Hypothetical protein T04A8.5 [Caenorhabditis elegans] ref|NP_497958.1| T04A8.5 [Caenorhabditis elegans] 0.0
blast CAE71157 Hypothetical protein CBG18013 [Caenorhabditis briggsae] 0.0
blast CAG10958 unnamed protein product [Tetraodon nigroviridis] 1.0E-119
Protein Domains
Database ID Description E-Value
Pfam IPR000583 EMBL-EBI Glutamine amidotransferase, class-II 2.7E-25
Pfam IPR000836 EMBL-EBI Phosphoribosyltransferase 3.0E-8
Pfam IPR000583 EMBL-EBI Glutamine amidotransferase, class-II 5.3E-18
Pfam IPR000836 EMBL-EBI Phosphoribosyltransferase 3.0E-8
Sequence
Target Sequence 
>C. ELEGANS:191910_AT
gttccagattcttcgctgagtgcagcaattggatacgcttctcagtctggaatcacatat
gaacctgttttacacagaaattcatatgttggaagatcatttatagaaccaaatgatgag
atgagacaaaatgcgattaaaatgaaatttggagtattgaagaaaaagattcatggacaa
aggattgtgttagtagatgattcaattgtacgtggaaatacgatgagaactttggtaaaa
atgttaagagatgctggagcaaaagaggttcatctacgaattgcttccccgcctgtaaaa
ttcccatgttttatgggaatcaacattccaaccacaaaggaattgattgctgccgaaaaa
acaattccagaaatctgccaatttgttggagccgattcagtacggtatctttcggttgac
ggtttagtttcgtctgttcaaaaaggaatcgaacgagctgccaacttctctccaggacat
tgcaccgcatgtctca

BLASTn GenBank NR
Probe Info
Probe Sequence(5'-3') Probe X Probe Y Probe Interrogation
Position 		Strandedness
GTTCCAGATTCTTCGCTGAGTGCAG 708 439 928 Antisense
GCAATTGGATACGCTTCTCAGTCTG 427 323 952 Antisense
GATACGCTTCTCAGTCTGGAATCAC 167 425 959 Antisense
GAATCACATATGAACCTGTTTTACA 529 327 977 Antisense
GAGGTTCATCTACGAATTGCTTCCC 319 403 1192 Antisense
GCCAATTTGTTGGAGCCGATTCAGT 609 277 1304 Antisense
CAGTACGGTATCTTTCGGTTGACGG 37 189 1325 Antisense
TGACGGTTTAGTTTCGTCTGTTCAA 603 567 1344 Antisense
GAATCGAACGAGCTGCCAACTTCTC 537 329 1373 Antisense
CCAACTTCTCTCCAGGACATTGCAC 281 277 1388 Antisense
CCAGGACATTGCACCGCATGTCTCA 145 273 1399 Antisense
Sequence Source Affymetrix Proprietary Database