[Home] | [Total List]

[191907_s_at] protein kinase /// guanylate cyclase

Description ZC239.7 /REP_DB=WormBase Gene ID /WP=CE26332 /GEN=gcy-15 /TR=P91550 /GB=AAB37946.2 /SUBMIT=ST.LOUIS /CHR=2 /FEA=Sanger Annotation /DEF=guanylate cyclase
Cluster 6grp_total > 36      4grp_total > 45      6grp_cgc > 25      6grp_total_sub > Cup      4grp_rule_based > L1      

Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 219
1 2 3 4 range
A 193.7
(3)
M 		149.3
(1.6)
A 		21.2
(-2.6)
A 		9.7
(-3)
A 		184
B 216.9
(3)
P 		112.9
(0)
A 		18.3
(-2.6)
A 		5.9
(-3)
A 		211
C 224.9
(3)
P 		80.3
(-1.8)
A 		91.4
(-1.4)
A 		43.6
(-3)
A 		181
avr 211.8
(3) 		114.2
(-0) 		43.6
(-2.3) 		19.7
(-3) 		192

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 162
1 2 3 4 5 6 range
A 103.4
(3)
A 		75.5
(1)
A 		47.6
(-0.9)
A 		76.4
(1.1)
A 		18.5
(-3)
A 		54.6
(-0.4)
A 		85
B 180.6
(3)
A 		115.7
(0.3)
A 		106.3
(-0)
A 		72.8
(-1.4)
A 		33.8
(-3)
A 		117.5
(0.4)
A 		147
C 110
(3)
A 		108
(2.8)
A 		83.7
(-0.1)
A 		97.9
(1.6)
A 		58.6
(-3)
A 		100.4
(1.9)
A 		51
avr 131.3
(3) 		99.7
(1) 		79.2
(-0.3) 		82.4
(-0.1) 		37
(-3) 		90.8
(0.4) 		94
No Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 73
1 2 3 4 range
A 70.5
(3)
M 		32.4
(-0.3)
A 		5.5
(-2.6)
A 		1.4
(-3)
A 		69
B 69.2
(3)
P 		27.9
(-0.6)
A 		4.2
(-2.7)
A 		1.3
(-3)
A 		68
C 74.5
(3)
P 		23.1
(-1.6)
A 		31.9
(-0.8)
A 		7.3
(-3)
A 		67
avr 71.4
(3) 		27.8
(-0.8) 		13.9
(-2.1) 		3.3
(-3) 		68

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 57
1 2 3 4 5 6 range
A 19.1
(0.8)
A 		26.9
(3)
A 		10.4
(-1.6)
A 		19.4
(0.9)
A 		5.6
(-3)
A 		13.3
(-0.8)
A 		21
B 62.8
(3)
A 		38.5
(0)
A 		25.8
(-1.5)
A 		19.3
(-2.3)
A 		13.7
(-3)
A 		43.8
(0.7)
A 		49
C 40.8
(3)
A 		32.9
(0.8)
A 		21.3
(-2.4)
A 		19.7
(-2.8)
A 		19
(-3)
A 		33.6
(1)
A 		22
avr 40.9
(3) 		32.8
(1.3) 		19.2
(-1.6) 		19.5
(-1.6) 		12.8
(-3) 		30.2
(0.7) 		28
NetAffx Links Cluster Members
Consensus/Exemplar
Group Members
GeneChip Array Information
Probe Set ID 191907_s_at
GeneChip Array C. elegans Genome Array
Organism Common Name Nematode
Probe Design Information
Transcript ID(Array Design) affy.Ce.5070
Sequence Type Exemplar sequence
Representative Public ID ZC239.7 NCBI
Target Description ZC239.7 /REP_DB=WormBase Gene ID /WP=CE26332 /GEN=gcy-15 /TR=P91550 /GB=AAB37946.2 /SUBMIT=ST.LOUIS /CHR=2 /FEA=Sanger Annotation /DEF=guanylate cyclase
Cluster Evidence This cluster is supported by a Sanger Annotation.
Annotation Method Description
Annotation Description This probe set was annotated using the Matching Probes based pipeline to a RefSeq identifier using 1 transcript(s).
Annotation Grade This is a grade A annotation.
Annotation Transcript Cluster (# of Matching Probes) NM_062067(11), NM_061923(11)
Transcript Assignments
Representative
Transcript		 Description Matching Probes Related Probesets by Grade
NM_062067 NCBI Caenorhabditis elegans Guanylyl CYclase family member (gcy-15) (gcy-15) mRNA, complete cds. 11/11 A 
NM_061923 NCBI Caenorhabditis elegans Guanylyl CYclase family member (gcy-21) (gcy-21) mRNA, complete cds. 11/11 A 
SNAP00000023614 ENSEMBL cdna:SNAP chromosome:CEL140:II:2662257:2664616:1 11/11 None
GENEFINDER00000023622 ENSEMBL cdna:GeneFinder chromosome:CEL140:II:2659389:2664616:1 11/11 None
SNAP00000024287 ENSEMBL cdna:SNAP chromosome:CEL140:II:3192415:3198111:-1 11/11 None
GENEFINDER00000024303 ENSEMBL cdna:GeneFinder chromosome:CEL140:II:3192419:3200901:-1 11/11 None
F22E5.3 ENSEMBL cdna:known chromosome:CEL140:II:2659671:2665023:1 gene:F22E5.3 11/11 A 
ZC239.7 ENSEMBL cdna:known chromosome:CEL140:II:3192415:3196870:-1 gene:ZC239.7 11/11 A 
Annotation Notes
There are no noteworthy cross hybridizing mRNAs found for this probe set.
Genomic Alignment of Consensus/Exemplar Sequence
Assembly Wormbase March 2004
Alignment(s)
Position Identity Coverage Cytoband
chrII:2660091-2664615(+) 94.84 94.84
chrII:3192413-3196869(-) 100.0 100.0
Public Domain and Genome References
Gene Title protein kinase
guanylate cyclase
Gene Symbol gcy-21
gcy-15
Ensembl F22E5.3
ZC239.7
Entrez Gene 191648 Entrez gene
191651 Entrez gene
SwissProt O16715 EMBL-EBI
P91550 EMBL-EBI
WormBase CE09555 Wormbase
CE26332 Wormbase
Functional Annotations
Gene Ontology
GO Biological Process (view graph)
ID Description Evidence Links
6468 protein amino acid phosphorylation inferred from electronic annotation QuickGO AmiGO
7242 intracellular signaling cascade inferred from electronic annotation QuickGO AmiGO
GO Molecular Function (view graph)
ID Description Evidence Links
4383 guanylate cyclase activity inferred from electronic annotation QuickGO AmiGO
4672 protein kinase activity inferred from electronic annotation QuickGO AmiGO
4674 protein serine/threonine kinase activity inferred from electronic annotation QuickGO AmiGO
4713 protein-tyrosine kinase activity inferred from electronic annotation QuickGO AmiGO
5524 ATP binding inferred from electronic annotation QuickGO AmiGO
Protein Similarities
Method ID Description E-Value
blast AAB37946 Guanylyl cyclase protein 15 [Caenorhabditis elegans] ref|NP_494468.1| Guanylyl CYclase family member (gcy-15) [Caenorhabditis elegans] 0.0
blast NP_494324 Guanylyl CYclase family member (gcy-21) [Caenorhabditis elegans] gb|AAB66169.1| Guanylyl cyclase protein 21 [Caenorhabditis elegans] 0.0
blast CAE72387 Hypothetical protein CBG19543 [Caenorhabditis briggsae] 0.0
Protein Domains
Database ID Description E-Value
Pfam IPR000719 EMBL-EBI Protein kinase 3.6E-8
Pfam IPR000719 EMBL-EBI Protein kinase 6.2E-5
Pfam IPR001054 EMBL-EBI Guanylate cyclase 1.3E-77
Pfam IPR000719 EMBL-EBI Protein kinase 6.5E-9
Pfam IPR000719 EMBL-EBI Protein kinase 6.2E-5
Pfam IPR001054 EMBL-EBI Guanylate cyclase 4.3E-85
Pfam IPR000719 EMBL-EBI Protein kinase 6.5E-9
Pfam IPR000719 EMBL-EBI Protein kinase 6.2E-5
Pfam IPR001054 EMBL-EBI Guanylate cyclase 4.3E-85
Pfam IPR000719 EMBL-EBI Protein kinase 6.5E-9
Pfam IPR000719 EMBL-EBI Protein kinase 6.2E-5
Pfam IPR001054 EMBL-EBI Guanylate cyclase 4.3E-85
Pfam IPR000719 EMBL-EBI Protein kinase 3.6E-8
Pfam IPR003003 EMBL-EBI 7TM chemoreceptor, subfamily 2 1.0E-80
Pfam IPR003003 EMBL-EBI 7TM chemoreceptor, subfamily 2 4.4E-70
Pfam IPR000719 EMBL-EBI Protein kinase 3.6E-8
Pfam IPR000719 EMBL-EBI Protein kinase 6.2E-5
Pfam IPR001054 EMBL-EBI Guanylate cyclase 4.3E-85
Trans Membrane
ID Number Of Domains Domain Boundaries
NP_494468.1 1 317-339
NP_494324.1 1 378-400
F22E5.3 1 378-400
ZC239.7 1 317-339
GENEFINDER00000023622 2 5-22,501-523
SNAP00000024287 3 7-29,64-86,501-523
GENEFINDER00000024303 16 10-32,45-64,91-113,134-156,189-211,241-263,273-295,363-385,395-413,420-439,444-463,484-506,539-561,596-618,623-645,1128-1150
Sequence
Target Sequence 
>C. ELEGANS:191907_S_AT
tacacggtcttcgatcgaatcattgatcaattcgacgtctacaaagtggagacaattgca
gacgcttatatggtcgcctcgggattgcctgtcccaaatggaaaccatcacgccggggag
atcgcttctctcgggcttgctctgctgaaagctgttgagagcttcaaaatccgtcaccta
ccaaatgagaaggtccgtctaagaattggtatgaactcgggaccttgtgtagcaggggtt
gttgggttgaagatgccgcgatattgcttgttcggggacactgtgaacacggcaagtcgc
atggagagtaatggaattcgtaagtttttttgggtggcagaacctgtgagttctctccgc
atcaactgctccggcaccgccaaagaaattctcgaccagctcggtggctatgagatcgaa
gaacgcggaattgtggagatgaagggaaaaggcaaacagatgacgtattttgtgagaggc
gagaattcggatatgagaagagagcggattatcagagaacgtgtcaagttcgcaagcttg

BLASTn GenBank NR
Probe Info
Probe Sequence(5'-3') Probe X Probe Y Probe Interrogation
Position 		Strandedness
TACACGGTCTTCGATCGAATCATTG 439 643 2434 Antisense
GTGGAGACAATTGCAGACGCTTATA 415 489 2479 Antisense
GTATGAACTCGGGACCTTGTGTAGC 423 453 2642 Antisense
GGGACCTTGTGTAGCAGGGGTTGTT 408 495 2652 Antisense
GAAGATGCCGCGATATTGCTTGTTC 670 337 2682 Antisense
GCCGCGATATTGCTTGTTCGGGGAC 451 285 2688 Antisense
GTGAACACGGCAAGTCGCATGGAGA 604 481 2716 Antisense
TCCGGCACCGCCAAAGAAATTCTCG 181 595 2803 Antisense
CTCGACCAGCTCGGTGGCTATGAGA 408 233 2824 Antisense
GAGCGGATTATCAGAGAACGTGTCA 100 387 2935 Antisense
AGAACGTGTCAAGTTCGCAAGCTTG 492 73 2949 Antisense
Sequence Source Affymetrix Proprietary Database