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[191903_s_at] protein-tyrosine phosphatase

Description W03F11.4 /REP_DB=WormBase Gene ID /WP=CE28098 /TR=O01777 /GB=AAK18987.2 /SUBMIT=ST.LOUIS /CHR=1 /FEA=Sanger Annotation /DEF=protein-tyrosine phosphatase
Cluster 6grp_total > 87      4grp_total > 25      6grp_total_sub > Increase      6grp_rule_based > S6      

Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 52
1 2 3 4 range
A 6.7
(-3)
A 		22.4
(-0.3)
A 		14.2
(-1.7)
A 		41.6
(3)
A 		35
B 22.2
(-2.1)
A 		54.1
(2.3)
A 		58.9
(3)
A 		16.1
(-3)
A 		43
C 39.7
(3)
A 		7.3
(-2.9)
A 		6.5
(-3)
A 		33
(1.8)
A 		33
avr 22.9
(-3) 		27.9
(1.1) 		26.5
(-0) 		30.2
(3) 		7

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 84
1 2 3 4 5 6 range
A 30.6
(-1.6)
A 		10.3
(-3)
A 		29.6
(-1.6)
A 		27.3
(-1.8)
A 		65.4
(0.9)
A 		94.3
(3)
P 		84
B 36.6
(-2.3)
A 		29.5
(-3)
A 		35.4
(-2.4)
A 		33.9
(-2.6)
A 		44.3
(-1.6)
A 		92.6
(3)
P 		63
C 25.8
(-3)
A 		28.6
(-2.7)
A 		25.5
(-3)
A 		74.6
(1.5)
A 		71.8
(1.3)
M 		90.6
(3)
P 		65
avr 31
(-2.3) 		22.8
(-3) 		30.2
(-2.4) 		45.3
(-1.1) 		60.5
(0.2) 		92.5
(3) 		70
No Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 12
1 2 3 4 range
A 2.5
(-3)
A 		4.9
(1)
A 		3.7
(-1)
A 		6.1
(3)
A 		4
B 7.1
(-0.8)
A 		13.4
(2.8)
A 		13.7
(3)
A 		3.4
(-3)
A 		10
C 13.1
(3)
A 		2.1
(-3)
A 		2.3
(-2.9)
A 		5.6
(-1.1)
A 		11
avr 7.6
(3) 		6.8
(1.2) 		6.6
(0.7) 		5
(-3) 		3

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 31
1 2 3 4 5 6 range
A 5.6
(-2.4)
A 		3.7
(-3)
A 		6.4
(-2.2)
A 		6.9
(-2)
A 		19.7
(2)
A 		22.9
(3)
P 		19
B 12.8
(-2)
A 		9.8
(-2.7)
A 		8.6
(-3)
A 		9
(-2.9)
A 		18
(-0.8)
A 		34.5
(3)
P 		26
C 9.6
(-2.2)
A 		8.7
(-2.4)
A 		6.5
(-3)
A 		15
(-0.9)
A 		23.2
(1.2)
M 		30.3
(3)
P 		24
avr 9.3
(-2.4) 		7.4
(-2.9) 		7.2
(-3) 		10.3
(-2.2) 		20.3
(0.6) 		29.2
(3) 		22
NetAffx Links Cluster Members
Consensus/Exemplar
Group Members
GeneChip Array Information
Probe Set ID 191903_s_at
GeneChip Array C. elegans Genome Array
Organism Common Name Nematode
Probe Design Information
Transcript ID(Array Design) affy.Ce.242
Sequence Type Exemplar sequence
Representative Public ID W03F11.4 NCBI
Target Description W03F11.4 /REP_DB=WormBase Gene ID /WP=CE28098 /TR=O01777 /GB=AAK18987.2 /SUBMIT=ST.LOUIS /CHR=1 /FEA=Sanger Annotation /DEF=protein-tyrosine phosphatase
Cluster Evidence This cluster is supported by a Sanger Annotation.
Annotation Method Description
Annotation Description This probe set was annotated using the Matching Probes based pipeline to a RefSeq identifier using 1 transcript(s).
Annotation Grade This is a grade A annotation.
Annotation Transcript Cluster (# of Matching Probes) NM_058544(11)
Transcript Assignments
Representative
Transcript		 Description Matching Probes Related Probesets by Grade
NM_058544 NCBI Caenorhabditis elegans W03F11.4 (W03F11.4) mRNA, complete cds. 11/11 None
W03F11.4 ENSEMBL cdna:known chromosome:CEL140:I:2235637:2241358:-1 gene:W03F11.4 11/11 None
Annotation Notes
There are no noteworthy cross hybridizing mRNAs found for this probe set.
Genomic Alignment of Consensus/Exemplar Sequence
Assembly Wormbase March 2004
Alignment(s)
Position Identity Coverage Cytoband
chrI:2235641-2241072(-) 100.0 100.0
Public Domain and Genome References
Gene Title protein-tyrosine phosphatase
Ensembl W03F11.4
Entrez Gene 171780 Entrez gene
SwissProt O01777 EMBL-EBI
WormBase CE28098 Wormbase
Functional Annotations
Gene Ontology
GO Biological Process (view graph)
ID Description Evidence Links
6470 protein amino acid dephosphorylation inferred from electronic annotation QuickGO AmiGO
GO Molecular Function (view graph)
ID Description Evidence Links
4721 phosphoprotein phosphatase activity inferred from electronic annotation QuickGO AmiGO
4725 protein tyrosine phosphatase activity inferred from electronic annotation QuickGO AmiGO
Protein Similarities
Method ID Description E-Value
blast AAK18987 Hypothetical protein W03F11.4 [Caenorhabditis elegans] ref|NP_490945.1| W03F11.4 [Caenorhabditis elegans] 0.0
blast CAB04464 Hypothetical protein F54F12.1 [Caenorhabditis elegans] ref|NP_499709.1| F54F12.1 [Caenorhabditis elegans] 6.0E-84
blast AAF39870 Hypothetical protein H06I04.5 [Caenorhabditis elegans] ref|NP_497652.2| H06I04.5 [Caenorhabditis elegans] 4.0E-76
Protein Domains
Database ID Description E-Value
scop a.4.5.MarR-like transcriptional regulators All alpha proteins; DNA/RNA-binding 3-helical bundle; "Winged helix" DNA-binding domain; MarR-like transcriptional regulators 5.80000019073486
Pfam IPR003125 EMBL-EBI Protein of unknown function WSN 2.9E-28
Pfam IPR000242 EMBL-EBI Tyrosine specific protein phosphatase 6.7E-70
Trans Membrane
ID Number Of Domains Domain Boundaries
NP_490945.1 2 29-51,874-896
W03F11.4 2 29-51,874-896
Sequence
Target Sequence 
>C. ELEGANS:191903_S_AT
gcactgctcggttggtgttggacgtacaggaacacttgtcgctatcaagtatggtattca
gttgtgctcgaagcaagaggtatcggatatggcattggttgtggatcccgttcgtgcttg
ccgttacggcgcagttcaaactgagcagcaactgatctacatgctcctctgcatcacaaa
agccttgatggaaaaagccggtgtactcttctgggacaactacaatgctcttcactatta
ttacgacaaactccagacggactattacgagccttatctcaaaaaggacgagaaggaccc
ggaactgcttgcggcgaagaa

BLASTn GenBank NR
Probe Info
Probe Sequence(5'-3') Probe X Probe Y Probe Interrogation
Position 		Strandedness
GCACTGCTCGGTTGGTGTTGGACGT 54 315 3504 Antisense
GGACGTACAGGAACACTTGTCGCTA 48 525 3523 Antisense
TATGGCATTGGTTGTGGATCCCGTT 551 651 3591 Antisense
CGTGCTTGCCGTTACGGCGCAGTTC 11 245 3616 Antisense
AGCAACTGATCTACATGCTCCTCTG 247 77 3650 Antisense
TGCTCCTCTGCATCACAAAAGCCTT 626 581 3665 Antisense
GAAAAAGCCGGTGTACTCTTCTGGG 591 351 3694 Antisense
GGACAACTACAATGCTCTTCACTAT 43 527 3717 Antisense
TCCAGACGGACTATTACGAGCCTTA 670 585 3755 Antisense
AGGACGAGAAGGACCCGGAACTGCT 350 55 3788 Antisense
ACCCGGAACTGCTTGCGGCGAAGAA 648 87 3800 Antisense
Sequence Source Affymetrix Proprietary Database