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[191899_at] protein-tyrosine phosphatase

Description M04G7.2 /REP_DB=WormBase Gene ID /WP=CE17191 /TR=O44180 /GB=AAB88365.1 /SUBMIT=ST.LOUIS /CHR=4 /FEA=Sanger Annotation /DEF=protein-tyrosine phosphatase
Cluster 6grp_total > 95      4grp_total > 23      6grp_total_sub > Increase      6grp_rule_based > S5      

Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 29
1 2 3 4 range
A 8.1
(-2)
A 		3.5
(-3)
A 		4.1
(-2.9)
A 		31.5
(3)
A 		28
B 22.4
(3)
A 		6.5
(-1.7)
A 		4.6
(-2.3)
A 		2.3
(-3)
A 		20
C 17.2
(3)
A 		5.8
(-1.7)
A 		2.6
(-3)
A 		6.5
(-1.4)
A 		15
avr 15.9
(3) 		5.3
(-2.3) 		3.8
(-3) 		13.4
(1.8) 		12

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 41
1 2 3 4 5 6 range
A 2.8
(-2.7)
A 		1.4
(-3)
A 		2.3
(-2.8)
A 		29.4
(2.6)
A 		31.4
(3)
A 		30.8
(2.9)
A 		30
B 3
(-2.8)
A 		2.4
(-3)
A 		4.3
(-2.4)
A 		19.9
(2.8)
A 		3.1
(-2.8)
A 		20.5
(3)
A 		18
C 4.1
(-3)
A 		6.7
(-2.6)
A 		9.5
(-2.2)
A 		5.6
(-2.8)
A 		42.8
(3)
A 		20.5
(-0.5)
A 		39
avr 3.3
(-3) 		3.5
(-2.9) 		5.4
(-2.4) 		18.3
(1) 		25.8
(3) 		23.9
(2.5) 		23
No Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 7
1 2 3 4 range
A 2.9
(0.3)
A 		0.8
(-3)
A 		1.1
(-2.5)
A 		4.6
(3)
A 		4
B 7.1
(3)
A 		1.6
(-2)
A 		1.1
(-2.5)
A 		0.5
(-3)
A 		7
C 5.7
(3)
A 		1.7
(-2)
A 		0.9
(-3)
A 		1.1
(-2.8)
A 		5
avr 5.2
(3) 		1.4
(-2.4) 		1
(-3) 		2.1
(-1.4) 		4

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 13
1 2 3 4 5 6 range
A 0.5
(-3)
A 		0.5
(-3)
A 		0.5
(-3)
A 		7.5
(1.7)
A 		9.5
(3)
A 		7.5
(1.7)
A 		9
B 1
(-2.8)
A 		0.8
(-3)
A 		1
(-2.8)
A 		5.3
(0.9)
A 		1.3
(-2.6)
A 		7.7
(3)
A 		7
C 1.5
(-2.8)
A 		2.1
(-2.5)
A 		2.4
(-2.4)
A 		1.1
(-3)
A 		13.8
(3)
A 		6.8
(-0.3)
A 		13
avr 1
(-3) 		1.1
(-2.9) 		1.3
(-2.8) 		4.6
(0) 		8.2
(3) 		7.3
(2.3) 		7
NetAffx Links Cluster Members
Consensus/Exemplar
GeneChip Array Information
Probe Set ID 191899_at
GeneChip Array C. elegans Genome Array
Organism Common Name Nematode
Probe Design Information
Transcript ID(Array Design) affy.Ce.10363
Sequence Type Exemplar sequence
Representative Public ID M04G7.2 NCBI
Target Description M04G7.2 /REP_DB=WormBase Gene ID /WP=CE17191 /TR=O44180 /GB=AAB88365.1 /SUBMIT=ST.LOUIS /CHR=4 /FEA=Sanger Annotation /DEF=protein-tyrosine phosphatase
Cluster Evidence This cluster is supported by a Sanger Annotation.
Annotation Method Description
Annotation Description This probe set was annotated using the Matching Probes based pipeline to a RefSeq identifier using 1 transcript(s).
Annotation Grade This is a grade A annotation.
Annotation Transcript Cluster (# of Matching Probes) NM_067533(11)
Transcript Assignments
Representative
Transcript		 Description Matching Probes Related Probesets by Grade
NM_067533 NCBI Caenorhabditis elegans M04G7.2 (M04G7.2) mRNA, complete cds. 11/11 A 
SNAP00000026150 ENSEMBL cdna:SNAP chromosome:CEL140:IV:458063:459815:-1 11/11 None
GENEFINDER00000026154 ENSEMBL cdna:GeneFinder chromosome:CEL140:IV:458063:460978:-1 11/11 None
M04G7.2 ENSEMBL cdna:known chromosome:CEL140:IV:458032:460549:-1 gene:M04G7.2 11/11 A 
Annotation Notes
There are no noteworthy cross hybridizing mRNAs found for this probe set.
Genomic Alignment of Consensus/Exemplar Sequence
Assembly Wormbase March 2004
Alignment(s)
Position Identity Coverage Cytoband
chrIV:458062-460447(-) 100.0 100.0
Public Domain and Genome References
Gene Title protein-tyrosine phosphatase
Ensembl M04G7.2
Entrez Gene 187449 Entrez gene
SwissProt O44180 EMBL-EBI
WormBase CE17191 Wormbase
Functional Annotations
Gene Ontology
GO Biological Process (view graph)
ID Description Evidence Links
6470 protein amino acid dephosphorylation inferred from electronic annotation QuickGO AmiGO
GO Molecular Function (view graph)
ID Description Evidence Links
4721 phosphoprotein phosphatase activity inferred from electronic annotation QuickGO AmiGO
4725 protein tyrosine phosphatase activity inferred from electronic annotation QuickGO AmiGO
Protein Similarities
Method ID Description E-Value
blast AAB88365 Hypothetical protein M04G7.2 [Caenorhabditis elegans] ref|NP_499934.1| M04G7.2 [Caenorhabditis elegans] 0.0
blast AAF60945 Hypothetical protein ZK616.7 [Caenorhabditis elegans] ref|NP_500806.1| ZK616.7 [Caenorhabditis elegans] 1.0E-161
blast CAE67290 Hypothetical protein CBG12739 [Caenorhabditis briggsae] 1.0E-158
Protein Domains
Database ID Description E-Value
Pfam IPR000242 EMBL-EBI Tyrosine specific protein phosphatase 2.2E-102
Pfam IPR000242 EMBL-EBI Tyrosine specific protein phosphatase 2.2E-102
Pfam IPR000242 EMBL-EBI Tyrosine specific protein phosphatase 2.2E-102
Sequence
Target Sequence 
>C. ELEGANS:191899_AT
acacgacggcgattgtgatgctctgtcaattcctcgagacgaatcgtgagaagtgcgccg
agtacttcccgagaaatgcacattgttgcctgcaattcgacaagtttagtgtaaactacg
aggattcaacggtgaacaagtctctggtgacgactcgcctcaacttgagctatgagggcg
agacgcgattgatcactcactggctatggaaggaatggcccgactggcaagtgcctgaat
cctcagaggtcatgctgaagatcttgagaaagatcagagcgagaagtacacctccagtta
ttcattgttcggcgggagttggccgttcgggaacgctgatggctgttgagattgcattgc
aatcgattcatactcacttcacgc

BLASTn GenBank NR
Probe Info
Probe Sequence(5'-3') Probe X Probe Y Probe Interrogation
Position 		Strandedness
ACACGACGGCGATTGTGATGCTCTG 577 109 1085 Antisense
CCGAGAAATGCACATTGTTGCCTGC 560 263 1153 Antisense
TGCACATTGTTGCCTGCAATTCGAC 80 577 1161 Antisense
GCAATTCGACAAGTTTAGTGTAAAC 10 323 1176 Antisense
CTCGCCTCAACTTGAGCTATGAGGG 441 233 1238 Antisense
GAGGGCGAGACGCGATTGATCACTC 535 401 1258 Antisense
GAGACGCGATTGATCACTCACTGGC 46 395 1264 Antisense
GATCACTCACTGGCTATGGAAGGAA 285 421 1275 Antisense
TGGCCCGACTGGCAAGTGCCTGAAT 554 543 1300 Antisense
AAGTGCCTGAATCCTCAGAGGTCAT 693 157 1313 Antisense
CAATCGATTCATACTCACTTCACGC 84 183 1444 Antisense
Sequence Source Affymetrix Proprietary Database