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[191879_at] TNF-alpha induced Protein B12

Description D2045.8 /REP_DB=WormBase Gene ID /WP=CE00608 /TR=Q18986 /GB=CAA84696.1 /SUBMIT=HINXTON /CHR=3 /FEA=Sanger Annotation /DEF=TNF-alpha induced Protein B12
Cluster 6grp_highest_10_10 > 05      6grp_high1_10_10 > 50      4grp_high_8_8 > 49      6grp_highest_nonorm > 61      6grp_total > 42      4grp_total > 54      6grp_highest_sub > 03_04      6grp_high1_sub > 03_04      6grp_total_sub > Hat      

Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 510
1 2 3 4 range
A 703.5
(3)
P 		547.1
(0.1)
P 		520.3
(-0.4)
P 		383
(-3)
M 		321
B 633.8
(3)
P 		445.2
(-1.7)
P 		484.8
(-0.7)
P 		392.6
(-3)
P 		241
C 832.3
(3)
P 		475.7
(-1.2)
P 		502
(-0.9)
P 		322.3
(-3)
P 		510
avr 723.2
(3) 		489.3
(-0.9) 		502.4
(-0.7) 		366
(-3) 		357

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 440
1 2 3 4 5 6 range
A 473.3
(1)
P 		374.4
(-0.8)
P 		497.6
(1.5)
P 		581.2
(3)
P 		361
(-1)
P 		251.8
(-3)
P 		329
B 390.5
(2.2)
P 		404.8
(2.6)
P 		287.1
(-0.6)
P 		381.9
(2)
P 		418.6
(3)
P 		198.4
(-3)
P 		220
C 429.1
(0.4)
P 		323
(-1.1)
P 		622.4
(3)
P 		378.1
(-0.3)
P 		360
(-0.6)
P 		182.2
(-3)
P 		440
avr 431
(2.1) 		367.4
(0.6) 		469
(3) 		447.1
(2.5) 		379.9
(0.9) 		210.8
(-3) 		258
No Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 221
1 2 3 4 range
A 256.1
(3)
P 		118.8
(-1.1)
P 		136
(-0.6)
P 		56.1
(-3)
M 		200
B 202.1
(3)
P 		110
(-1.7)
P 		112.3
(-1.6)
P 		83.7
(-3)
P 		118
C 275.5
(3)
P 		136.8
(-0.8)
P 		174.9
(0.3)
P 		54.3
(-3)
P 		221
avr 244.6
(3) 		121.9
(-1.1) 		141.1
(-0.5) 		64.7
(-3) 		180

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 109
1 2 3 4 5 6 range
A 87.2
(-1.2)
P 		133.2
(2)
P 		108.4
(0.3)
P 		147.4
(3)
P 		108.9
(0.3)
P 		61.3
(-3)
P 		86
B 135.9
(1)
P 		134.7
(0.9)
P 		69.7
(-3)
P 		101.2
(-1.1)
P 		170.1
(3)
P 		74
(-2.7)
P 		100
C 159
(3)
P 		98.5
(-0.7)
P 		158.4
(3)
P 		76
(-2.1)
P 		116.5
(0.4)
P 		61
(-3)
P 		98
avr 127.4
(2.6) 		122.1
(2.1) 		112.2
(1.2) 		108.2
(0.9) 		131.8
(3) 		65.4
(-3) 		66
NetAffx Links Cluster Members
Consensus/Exemplar
GeneChip Array Information
Probe Set ID 191879_at
GeneChip Array C. elegans Genome Array
Organism Common Name Nematode
Probe Design Information
Transcript ID(Array Design) affy.Ce.6594
Sequence Type Exemplar sequence
Representative Public ID D2045.8 NCBI
Target Description D2045.8 /REP_DB=WormBase Gene ID /WP=CE00608 /TR=Q18986 /GB=CAA84696.1 /SUBMIT=HINXTON /CHR=3 /FEA=Sanger Annotation /DEF=TNF-alpha induced Protein B12
Cluster Evidence This cluster is supported by a Sanger Annotation.
Annotation Method Description
Annotation Description This probe set was annotated using the Matching Probes based pipeline to a RefSeq identifier using 1 transcript(s).
Annotation Grade This is a grade A annotation.
Annotation Transcript Cluster (# of Matching Probes) NM_066911(11)
Transcript Assignments
Representative
Transcript		 Description Matching Probes Related Probesets by Grade
NM_066911 NCBI Caenorhabditis elegans D2045.8 (D2045.8) mRNA, complete cds. 11/11 None
SNAP00000022545 ENSEMBL cdna:SNAP chromosome:CEL140:III:10482232:10483675:1 11/11 None
GENEFINDER00000022552 ENSEMBL cdna:GeneFinder chromosome:CEL140:III:10482232:10485310:1 11/11 None
D2045.8 ENSEMBL cdna:known chromosome:CEL140:III:10482208:10483762:1 gene:D2045.8 11/11 None
Annotation Notes
There are no noteworthy cross hybridizing mRNAs found for this probe set.
Genomic Alignment of Consensus/Exemplar Sequence
Assembly Wormbase March 2004
Alignment(s)
Position Identity Coverage Cytoband
chrIII:10482227-10483671(+) 100.0 100.0
Public Domain and Genome References
Gene Title TNF-alpha induced Protein B12
Ensembl D2045.8
Entrez Gene 176468 Entrez gene
SwissProt Q18986 EMBL-EBI
WormBase CE00608 Wormbase
Functional Annotations
Ortholog
ID Title Organism
CANINE:1596392_AT similar to potassium channel tetramerisation domain containing 10 cfa
CANINE:1594944_S_AT similar to potassium channel tetramerisation domain containing 10 cfa
CANINE_2:CFA.10243.2.S1_AT similar to potassium channel tetramerisation domain containing 10 cfa
CANINE_2:CFAAFFX.17019.1.S1_S_AT similar to potassium channel tetramerisation domain containing 10 cfa
DROSOPHILA_2:1640138_AT dm
DROSGENOME1:146639_AT dm
CHICKEN:GGA.8322.1.S1_AT similar to potassium channel tetramerisation domain containing 10; MSTP028 protein gga
CHICKEN:GGA.9174.1.S1_AT similar to potassium channel tetramerisation domain containing 10; MSTP028 protein gga
CHICKEN:GGA.9174.2.S1_A_AT similar to potassium channel tetramerisation domain containing 10; MSTP028 protein gga
CHICKEN:GGA.9174.3.S1_A_AT similar to potassium channel tetramerisation domain containing 10; MSTP028 protein gga
CHICKEN:GGA.9174.3.S1_S_AT similar to potassium channel tetramerisation domain containing 10; MSTP028 protein gga
CHICKEN:GGA.9174.3.S1_X_AT similar to potassium channel tetramerisation domain containing 10; MSTP028 protein gga
HG-U133B:223208_AT potassium channel tetramerisation domain containing 10 hs
HG-U133_PLUS_2:223208_AT potassium channel tetramerisation domain containing 10 hs
HU35KSUBA:H44269_AT potassium channel tetramerisation domain containing 10 hs
HU35KSUBB:RC_W47206_AT potassium channel tetramerisation domain containing 10 hs
HU35KSUBC:RC_AA027223_AT potassium channel tetramerisation domain containing 10 hs
HU35KSUBD:RC_AA219552_S_AT potassium channel tetramerisation domain containing 10 hs
U133_X3P:G11640563_3P_X_AT potassium channel tetramerisation domain containing 10 hs
U133_X3P:G11640563_3P_AT potassium channel tetramerisation domain containing 10 hs
U133_X3P:HS.302746.1.S1_3P_AT potassium channel tetramerisation domain containing 10 hs
HG-U133_PLUS_2:226518_AT potassium channel tetramerisation domain containing 10 hs
HG-U133B:226518_AT potassium channel tetramerisation domain containing 10 hs
HG-U95B:45292_AT potassium channel tetramerisation domain containing 10 hs
HG-U95B:45293_AT potassium channel tetramerisation domain containing 10 hs
HG-U95C:59907_AT Potassium channel tetramerisation domain containing 10 hs
HG-U95D:76101_AT Potassium channel tetramerisation domain containing 10 hs
MOE430A:1423694_AT potassium channel tetramerisation domain containing 10 mm
MOUSE430_2:1423694_AT potassium channel tetramerisation domain containing 10 mm
MOUSE430A_2:1423694_AT potassium channel tetramerisation domain containing 10 mm
MU11KSUBA:AA020128_S_AT potassium channel tetramerisation domain containing 10 mm
MG-U74AV2:94060_AT potassium channel tetramerisation domain containing 10 mm
MG-U74CV2:168391_F_AT potassium channel tetramerisation domain containing 10 mm
MU19KSUBB:TC31083_AT Potassium channel tetramerisation domain containing 10 (Kctd10), mRNA mm
MU19KSUBC:TC37152_AT Potassium channel tetramerisation domain containing 10 (Kctd10), mRNA mm
Gene Ontology
GO Biological Process (view graph)
ID Description Evidence Links
6813 potassium ion transport inferred from electronic annotation QuickGO AmiGO
GO Cellular Component (view graph)
ID Description Evidence Links
8076 voltage-gated potassium channel complex inferred from electronic annotation QuickGO AmiGO
16020 membrane inferred from electronic annotation QuickGO AmiGO
GO Molecular Function (view graph)
ID Description Evidence Links
5249 voltage-gated potassium channel activity inferred from electronic annotation QuickGO AmiGO
5515 protein binding inferred from electronic annotation QuickGO AmiGO
Protein Similarities
Method ID Description E-Value
blast CAA84696 Hypothetical protein D2045.8 [Caenorhabditis elegans] ref|NP_499312.1| D2045.8 [Caenorhabditis elegans] 1.0E-125
blast CAA84696 Hypothetical protein D2045.8 [Caenorhabditis elegans] ref|NP_499312.1| D2045.8 [Caenorhabditis elegans] 1.0E-107
blast CAE71468 Hypothetical protein CBG18386 [Caenorhabditis briggsae] 4.0E-85
blast CAE71468 Hypothetical protein CBG18386 [Caenorhabditis briggsae] 2.0E-80
blast XP_797819 PREDICTED: similar to potassium channel tetramerisation domain containing 10 [Strongylocentrotus purpuratus] 3.0E-27
Protein Domains
Database ID Description E-Value
Pfam IPR003131 EMBL-EBI K+ channel tetramerisation 6.3E-40
Sequence
Target Sequence 
>C. ELEGANS:191879_AT
gattccaaacatttccgactaattttgaatttcctccgagacggtcaaatagccctaccg
gattccgatcgtgaagttcgagaagttcttgcagaagccagttattttctattagaccca
ctgattgagctatgcggggaacgattggaacagtcactcaatccctattatcatctggtt
tcaacagtgttagaagccagaaagatcatttttgcaaccgaaaagccaattgtggtgttg
agattgccggtatacattgccacgagtggaaatcaaagctattatttcagcgagacaaag
tttcgagaattgtctgaggaataccacaaacacgtggcttttatcttaataaccgagccg
gagttcaacgaggattgctcatggagcttcttccttcgcgccaagaaaatcacc

BLASTn GenBank NR
Probe Info
Probe Sequence(5'-3') Probe X Probe Y Probe Interrogation
Position 		Strandedness
GATTCCAAACATTTCCGACTAATTT 5 431 169 Antisense
TTTTGAATTTCCTCCGAGACGGTCA 313 673 191 Antisense
GAGACGGTCAAATAGCCCTACCGGA 9 143 206 Antisense
GCCCTACCGGATTCCGATCGTGAAG 54 285 220 Antisense
TAGACCCACTGATTGAGCTATGCGG 239 653 281 Antisense
GGGGAACGATTGGAACAGTCACTCA 417 497 304 Antisense
AGTCACTCAATCCCTATTATCATCT 624 61 320 Antisense
GAGATTGCCGGTATACATTGCCACG 317 397 408 Antisense
CACAAACACGTGGCTTTTATCTTAA 149 195 493 Antisense
AACCGAGCCGGAGTTCAACGAGGAT 141 147 519 Antisense
CTTCCTTCGCGCCAAGAAAATCACC 36 219 558 Antisense
Sequence Source Affymetrix Proprietary Database