[Home] | [Total List]

[191877_at] adenylate cyclase

Description C10F3.3 /REP_DB=WormBase Gene ID /WP=CE24798 /GEN=acy-2 /TR=O16880 /GB=AAB69885.1 /SUBMIT=ST.LOUIS /CHR=5 /FEA=Sanger Annotation /DEF=adenylate cyclase
Cluster 6grp_high1_10_10 > 13      6grp_total > 23      4grp_total > 31      6grp_cgc > 31      6grp_high1_sub > De      6grp_cgc_sub > De      6grp_total_sub > Decrease      6grp_rule_based > S1      

Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 130
1 2 3 4 range
A 136.1
(3)
P 		22
(-3)
A 		31
(-2.5)
A 		74.6
(-0.2)
M 		114
B 152.1
(3)
P 		50.8
(-1.7)
P 		23.9
(-3)
A 		98.7
(0.5)
P 		128
C 133.5
(3)
P 		29.1
(-3)
A 		34.6
(-2.7)
A 		76.1
(-0.3)
P 		104
avr 140.6
(3) 		34
(-2.8) 		29.8
(-3) 		83.1
(-0.1) 		111

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 70
1 2 3 4 5 6 range
A 70.4
(2.8)
P 		72.2
(3)
P 		57.8
(1.1)
P 		46.8
(-0.3)
A 		38.8
(-1.3)
A 		26.1
(-3)
A 		46
B 96.1
(3)
P 		92.1
(2.6)
P 		55
(-1.1)
P 		59.8
(-0.6)
M 		35.6
(-3)
P 		43.7
(-2.2)
P 		61
C 78.7
(2.5)
P 		71.8
(1.8)
P 		83.4
(3)
P 		53.6
(-0.1)
P 		56.5
(0.2)
A 		26.1
(-3)
P 		57
avr 81.7
(3) 		78.7
(2.6) 		65.4
(1) 		53.4
(-0.4) 		43.6
(-1.6) 		32
(-3) 		50
No Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 45
1 2 3 4 range
A 49.6
(3)
P 		4.8
(-3)
A 		8.1
(-2.6)
A 		10.9
(-2.2)
M 		45
B 48.5
(3)
P 		12.5
(-2)
P 		5.5
(-3)
A 		21
(-0.8)
P 		43
C 44.2
(3)
P 		8.4
(-3)
A 		12.1
(-2.4)
A 		12.8
(-2.3)
P 		36
avr 47.4
(3) 		8.6
(-3) 		8.6
(-3) 		14.9
(-2) 		39

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 27
1 2 3 4 5 6 range
A 13
(-0.9)
P 		25.7
(3)
P 		12.6
(-1.1)
P 		11.9
(-1.3)
A 		11.7
(-1.3)
A 		6.3
(-3)
A 		19
B 33.4
(3)
P 		30.7
(2.2)
P 		13.4
(-3)
P 		15.8
(-2.3)
M 		14.5
(-2.7)
P 		16.3
(-2.1)
P 		20
C 29.2
(3)
P 		21.9
(0.9)
P 		21.2
(0.7)
P 		10.8
(-2.4)
P 		18.3
(-0.2)
A 		8.7
(-3)
P 		21
avr 25.2
(2.7) 		26.1
(3) 		15.7
(-1) 		12.8
(-2.1) 		14.8
(-1.3) 		10.4
(-3) 		16
NetAffx Links Cluster Members
Consensus/Exemplar
GeneChip Array Information
Probe Set ID 191877_at
GeneChip Array C. elegans Genome Array
Organism Common Name Nematode
Probe Design Information
Transcript ID(Array Design) affy.Ce.11785
Sequence Type Exemplar sequence
Representative Public ID C10F3.3 NCBI
Target Description C10F3.3 /REP_DB=WormBase Gene ID /WP=CE24798 /GEN=acy-2 /TR=O16880 /GB=AAB69885.1 /SUBMIT=ST.LOUIS /CHR=5 /FEA=Sanger Annotation /DEF=adenylate cyclase
Cluster Evidence This cluster is supported by a Sanger Annotation.
Annotation Method Description
Annotation Description This probe set was annotated using the Matching Probes based pipeline to a RefSeq identifier using 1 transcript(s).
Annotation Grade This is a grade A annotation.
Annotation Transcript Cluster (# of Matching Probes) NM_072152(11)
Transcript Assignments
Representative
Transcript		 Description Matching Probes Related Probesets by Grade
NM_072152 NCBI Caenorhabditis elegans Adenylyl CYclase family member (acy-2) (acy-2) mRNA, complete cds. 11/11 None
SNAP00000029256 ENSEMBL cdna:SNAP chromosome:CEL140:V:5978623:5984007:1 11/11 None
GENEFINDER00000029266 ENSEMBL cdna:GeneFinder chromosome:CEL140:V:5978623:5984007:1 11/11 None
C10F3.3 ENSEMBL cdna:known chromosome:CEL140:V:5978623:5984062:1 gene:C10F3.3 11/11 None
Annotation Notes
There are no noteworthy cross hybridizing mRNAs found for this probe set.
Genomic Alignment of Consensus/Exemplar Sequence
Assembly Wormbase March 2004
Alignment(s)
Position Identity Coverage Cytoband
chrV:5978622-5984007(+) 100.0 100.0
Public Domain and Genome References
Gene Title adenylate cyclase
Gene Symbol acy-2
Ensembl C10F3.3
Entrez Gene 191607 Entrez gene
SwissProt O16880 EMBL-EBI
WormBase CE24798 Wormbase
Functional Annotations
Ortholog
ID Title Organism
CANINE:1603029_AT similar to adenylate cyclase 2 cfa
CANINE:1598726_AT similar to adenylate cyclase 2 cfa
CANINE:1583817_AT similar to adenylate cyclase 2 cfa
CANINE_2:CFA.19117.1.S1_S_AT similar to adenylate cyclase 2 cfa
CANINE_2:CFA.19869.1.S1_S_AT similar to adenylate cyclase 2 cfa
CANINE_2:CFA.5847.1.A1_AT similar to adenylate cyclase 2 cfa
CANINE_2:CFA.6896.1.A1_AT similar to adenylate cyclase 2 cfa
CANINE_2:CFA.7446.1.A1_AT similar to adenylate cyclase 2 cfa
CANINE_2:CFAAFFX.16048.1.S1_S_AT similar to adenylate cyclase 2 cfa
DROSOPHILA_2:1628231_AT Adenylyl cyclase 76E dm
DROSGENOME1:153007_AT Adenylyl cyclase 76E dm
CHICKEN:GGAAFFX.8289.7.S1_S_AT similar to adenylate cyclase 2; ATP pyrophosphate-lyase; type II adenylate cyclase; adenylyl cyclase 2; adenylate cyclase II; 3,5-cyclic AMP synthetase gga
HUGENEFL:L21993_AT adenylate cyclase 2 (brain) hs
U133_X3P:HS.311561.0.S1_3P_AT adenylate cyclase 2 (brain) hs
U133_X3P:HS.2352.0.S2_3P_AT adenylate cyclase 2 (brain) hs
U133_X3P:HS.2352.0.S1_3P_AT adenylate cyclase 2 (brain) hs
HG-U133A_2:213217_AT adenylate cyclase 2 (brain) hs
HG-U133_PLUS_2:213217_AT adenylate cyclase 2 (brain) hs
HG-U133A:213217_AT adenylate cyclase 2 (brain) hs
HG-U133A_2:213219_AT adenylate cyclase 2 (brain) hs
HG-U133_PLUS_2:213219_AT adenylate cyclase 2 (brain) hs
HG-U133A:213219_AT adenylate cyclase 2 (brain) hs
HG-U133A_2:217687_AT adenylate cyclase 2 (brain) hs
HG-U133_PLUS_2:217687_AT adenylate cyclase 2 (brain) hs
HG-U133A:217687_AT adenylate cyclase 2 (brain) hs
HG-U95AV2:34686_AT adenylate cyclase 2 (brain) hs
HG-U95B:43881_AT Adenylate cyclase 2 (brain) hs
HU35KSUBB:RC_H17953_AT Adenylate cyclase 2 (brain) hs
HU35KSUBB:RC_R56130_AT Adenylate cyclase 2 (brain) hs
MU11KSUBB:MSA.17855.0_S_AT adenylate cyclase 2 mm
MG-U74AV2:103241_AT adenylate cyclase 2 mm
MOE430A:1455462_AT adenylate cyclase 2 mm
MOUSE430A_2:1455462_AT adenylate cyclase 2 mm
MOUSE430_2:1455462_AT adenylate cyclase 2 mm
MU19KSUBA:TC20026_AT Adenylate cyclase 2 (Adcy2), mRNA mm
RG-U34A:M80550_AT adenylate cyclase 2 rn
RG-U34C:RC_AI171250_AT adenylate cyclase 2 rn
RAE230A:1367978_AT adenylate cyclase 2 rn
RAT230_2:1367978_AT adenylate cyclase 2 rn
Gene Ontology
GO Biological Process (view graph)
ID Description Evidence Links
7242 intracellular signaling cascade inferred from electronic annotation QuickGO AmiGO
GO Cellular Component (view graph)
ID Description Evidence Links
5886 plasma membrane inferred from curator QuickGO AmiGO
GO Molecular Function (view graph)
ID Description Evidence Links
4383 guanylate cyclase activity inferred from electronic annotation QuickGO AmiGO
4016 adenylate cyclase activity inferred from sequence similarity QuickGO AmiGO
Protein Similarities
Method ID Description E-Value
blast AAB69885 Adenylyl cyclase protein 2 [Caenorhabditis elegans] ref|NP_504553.1| Adenylyl CYclase family member (acy-2) [Caenorhabditis elegans] 0.0
blast CAE64534 Hypothetical protein CBG09276 [Caenorhabditis briggsae] 0.0
blast XP_697742 PREDICTED: similar to mKIAA1060 protein [Danio rerio] 1.0E-132
Protein Domains
Database ID Description E-Value
Pfam IPR001054 EMBL-EBI Guanylate cyclase 2.1E-63
Pfam IPR001054 EMBL-EBI Guanylate cyclase 1.0E-68
Pfam IPR001054 EMBL-EBI Guanylate cyclase 2.1E-63
Pfam IPR001054 EMBL-EBI Guanylate cyclase 1.0E-68
Trans Membrane
ID Number Of Domains Domain Boundaries
NP_504553.1 12 36-58,78-100,112-134,149-166,173-192,202-224,616-638,642-664,671-693,703-725,732-754,760-782
C10F3.3 12 36-58,78-100,112-134,149-166,173-192,202-224,616-638,642-664,671-693,703-725,732-754,760-782
SNAP00000029256 6 30-52,510-532,539-561,571-593,600-622,628-650
GENEFINDER00000029266 12 36-58,78-100,112-134,149-166,173-192,202-224,616-638,642-664,671-693,703-725,732-754,760-782
Sequence
Target Sequence 
>C. ELEGANS:191877_AT
ctgcgaattcgataagttgctctcaaaaccaaagttttcaagtgtggaaaagatcaaaac
agttggaagtacgtacatggcagcagctggactaaatgagagtgaagctgattatgatga
tatttatctggaaaaacaaaattctggaaaatacaacaacaatattcgtcatggcaatat
ggcatttagaaatgcaaatttgatgattgaatttgccttggcaatgtcacaaattctgga
tgcactcaatcgagactcttttcaaaattttgaacttcgaattggcatgagtgttgggcc
attggtggctggagtaattggagcacaaaagcctcaatatgatatttggggtaacacggt
gaatcttgcaagtcgaatggatacacacggagaaccacggaagattcatgcaacaactga
tatgggaagagttttacaaacgggtggatatcgagtacagagtcgtggaaaaattcgggt
caagggagtcaaggaaccgatggaaacctttctgatcgaggtcgactccaaacgaaactc
ctcagtatccggcgagcaacaaaaccatagt

BLASTn GenBank NR
Probe Info
Probe Sequence(5'-3') Probe X Probe Y Probe Interrogation
Position 		Strandedness
CTGCGAATTCGATAAGTTGCTCTCA 335 237 2655 Antisense
GAAGTACGTACATGGCAGCAGCTGG 291 337 2720 Antisense
ATGTCACAAATTCTGGATGCACTCA 217 49 2878 Antisense
GATGCACTCAATCGAGACTCTTTTC 73 413 2893 Antisense
GCATGAGTGTTGGGCCATTGGTGGC 60 311 2939 Antisense
GGTAACACGGTGAATCTTGCAAGTC 137 505 3004 Antisense
GGATACACACGGAGAACCACGGAAG 490 429 3033 Antisense
GGAACCGATGGAAACCTTTCTGATC 489 529 3147 Antisense
GATCGAGGTCGACTCCAAACGAAAC 709 415 3168 Antisense
CAAACGAAACTCCTCAGTATCCGGC 561 191 3183 Antisense
ATCCGGCGAGCAACAAAACCATAGT 68 39 3201 Antisense
Sequence Source Affymetrix Proprietary Database