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[191850_s_at] flavin-containing monoxygenase

Description K08C7.2 /REP_DB=WormBase Gene ID /WP=CE21038 /TR=Q21311 /GB=CAA94291.1 /SUBMIT=HINXTON /CHR=4 /FEA=Sanger Annotation /DEF=dimethylaniline monooxygenase
Cluster 6grp_highest_10_10 > 38      6grp_high1_10_10 > 72      4grp_highest_8_8 > 15      4grp_high_8_8 > 06      6grp_highest_nonorm > 55      6grp_total > 73      4grp_total > 02      6grp_highest_sub > 04      6grp_cgc > 76      6grp_high1_sub > 04      6grp_cgc_sub > 03_04      6grp_total_sub > Hat      4grp_rule_based > L4      

Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 2418
1 2 3 4 range
A 855.8
(-3)
P 		1172.3
(-2.2)
P 		985.2
(-2.7)
P 		3274.1
(3)
P 		2418
B 1102.2
(-2.7)
P 		1126.5
(-2.7)
P 		1010.1
(-3)
P 		3020.5
(3)
P 		2010
C 941.7
(-3)
P 		924.9
(-3)
P 		1010.7
(-2.8)
P 		3120.7
(3)
P 		2196
avr 966.6
(-3) 		1074.6
(-2.7) 		1002
(-2.9) 		3138.4
(3) 		2172

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 1786
1 2 3 4 5 6 range
A 1261.7
(-3)
P 		1350.4
(-2.6)
P 		2464.9
(2)
P 		2700.6
(3)
P 		1580.1
(-1.7)
P 		1548.2
(-1.8)
P 		1439
B 1292.4
(-3)
P 		1550.5
(-1.4)
P 		2132.1
(2.1)
P 		2278.9
(3)
P 		1618.8
(-1)
P 		1679.2
(-0.6)
P 		987
C 914.2
(-3)
P 		1533.6
(-0.4)
P 		1786
(0.7)
P 		2325.6
(3)
P 		1529.6
(-0.4)
P 		1706.7
(0.4)
P 		1411
avr 1156.1
(-3) 		1478.2
(-1.5) 		2127.7
(1.6) 		2435
(3) 		1576.2
(-1) 		1644.7
(-0.7) 		1279
No Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 410
1 2 3 4 range
A 311.6
(-1.5)
P 		254.5
(-3)
P 		257.5
(-2.9)
P 		479.3
(3)
P 		225
B 351.5
(-1.3)
P 		278.2
(-2.4)
P 		234.1
(-3)
P 		643.7
(3)
P 		410
C 311.7
(-1.9)
P 		265.9
(-3)
P 		352.3
(-1)
P 		526.2
(3)
P 		260
avr 324.9
(-1.8) 		266.2
(-3) 		281.3
(-2.7) 		549.7
(3) 		284

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 452
1 2 3 4 5 6 range
A 232.6
(-3)
P 		480.3
(0.3)
P 		536.8
(1)
P 		684.9
(3)
P 		476.8
(0.2)
P 		376.9
(-1.1)
P 		452
B 449.7
(-3)
P 		516.1
(-1.1)
P 		517.7
(-1)
P 		603.6
(1.4)
P 		657.7
(3)
P 		626.2
(2.1)
P 		208
C 338.9
(-3)
P 		467.9
(0.3)
P 		454.6
(-0)
P 		467.7
(0.3)
P 		494.9
(1)
P 		571.3
(3)
P 		232
avr 340.4
(-3) 		488.1
(0.6) 		503
(1) 		585.4
(3) 		543.1
(2) 		524.8
(1.5) 		245
NetAffx Links Cluster Members
Consensus/Exemplar
Group Members
GeneChip Array Information
Probe Set ID 191850_s_at
GeneChip Array C. elegans Genome Array
Organism Common Name Nematode
Probe Design Information
Transcript ID(Array Design) affy.Ce.9804
Sequence Type Exemplar sequence
Representative Public ID K08C7.2 NCBI
Target Description K08C7.2 /REP_DB=WormBase Gene ID /WP=CE21038 /TR=Q21311 /GB=CAA94291.1 /SUBMIT=HINXTON /CHR=4 /FEA=Sanger Annotation /DEF=dimethylaniline monooxygenase
Cluster Evidence This cluster is supported by a Sanger Annotation.
Annotation Method Description
Annotation Description This probe set was annotated using the Matching Probes based pipeline to a RefSeq identifier using 1 transcript(s).
Annotation Grade This is a grade A annotation.
Annotation Transcript Cluster (# of Matching Probes) NM_069567(11)
Transcript Assignments
Representative
Transcript		 Description Matching Probes Related Probesets by Grade
NM_069567 NCBI Caenorhabditis elegans Flavin-containing MonoOxygenase family member (fmo-1) (fmo-1) mRNA, complete cds. 11/11 A 
SNAP00000016921 ENSEMBL cdna:SNAP chromosome:CEL140:IV:10662019:10664110:1 11/11 None
GENEFINDER00000016930 ENSEMBL cdna:GeneFinder chromosome:CEL140:IV:10662019:10664110:1 11/11 None
K08C7.2.2 ENSEMBL cdna:known chromosome:CEL140:IV:10661829:10664376:1 gene:K08C7.2 11/11 A 
K08C7.2.3 ENSEMBL cdna:known chromosome:CEL140:IV:10661995:10664363:1 gene:K08C7.2 11/11 None
K08C7.2.1 ENSEMBL cdna:known chromosome:CEL140:IV:10662019:10664376:1 gene:K08C7.2 11/11 A 
Annotation Notes
There are no noteworthy cross hybridizing mRNAs found for this probe set.
Genomic Alignment of Consensus/Exemplar Sequence
Assembly Wormbase March 2004
Alignment(s)
Position Identity Coverage Cytoband
chrIV:10662024-10664116(+) 100.0 100.0
Public Domain and Genome References
Gene Title flavin-containing monoxygenase
Gene Symbol fmo-1
Ensembl K08C7.2
Entrez Gene 177954 Entrez gene
SwissProt Q21311 EMBL-EBI
WormBase CE31710 Wormbase
Functional Annotations
Ortholog
ID Title Organism
ATH1-121501:260991_AT flavin-containing monooxygenase family protein / FMO family protein at
CANINE:1585429_AT similar to Dimethylaniline monooxygenase [N-oxide-forming] 2 (Pulmonary flavin-containing monooxygenase 2) (FMO 2) (Dimethylaniline oxidase 2) (FMO 1B1) cfa
CANINE_2:CFA.12371.1.A1_AT similar to Dimethylaniline monooxygenase [N-oxide-forming] 2 (Pulmonary flavin-containing monooxygenase 2) (FMO 2) (Dimethylaniline oxidase 2) (FMO 1B1) cfa
CANINE_2:CFA.12371.1.A1_S_AT similar to Dimethylaniline monooxygenase [N-oxide-forming] 2 (Pulmonary flavin-containing monooxygenase 2) (FMO 2) (Dimethylaniline oxidase 2) (FMO 1B1) cfa
HG-U133_PLUS_2:211726_S_AT flavin containing monooxygenase 2 hs
HG-U133A:211726_S_AT flavin containing monooxygenase 2 hs
HG-U133A_2:211726_S_AT flavin containing monooxygenase 2 hs
HU35KSUBB:RC_T64494_AT flavin containing monooxygenase 2 hs
HU35KSUBD:RC_AA399112_AT flavin containing monooxygenase 2 hs
HUGENEFL:Y09267_AT flavin containing monooxygenase 2 hs
U133_X3P:G13543471_3P_S_AT flavin containing monooxygenase 2 hs
U133_X3P:HS.133471.0.A1_3P_AT flavin containing monooxygenase 2 hs
HG-U133_PLUS_2:228268_AT flavin containing monooxygenase 2 hs
HG-U133B:228268_AT flavin containing monooxygenase 2 hs
HG-U95AV2:34935_AT flavin containing monooxygenase 2 hs
HG-U95B:59321_R_AT flavin containing monooxygenase 2 hs
HG-U95E:76769_AT flavin containing monooxygenase 2 hs
HG-U95E:83908_AT flavin containing monooxygenase 2 hs
HG-U95E:69740_I_AT Flavin containing monooxygenase 2 hs
HG-U95E:69742_R_AT Flavin containing monooxygenase 2 hs
HG-U95D:79079_R_AT Flavin containing monooxygenase 2 hs
MOUSE430_2:1453435_A_AT flavin containing monooxygenase 2 mm
MOE430B:1453435_A_AT flavin containing monooxygenase 2 mm
MOUSE430_2:1454005_AT flavin containing monooxygenase 2 mm
MOE430A:1454005_AT flavin containing monooxygenase 2 mm
MOUSE430A_2:1454005_AT flavin containing monooxygenase 2 mm
MOE430B:1435459_AT flavin containing monooxygenase 2 mm
MOUSE430_2:1435459_AT flavin containing monooxygenase 2 mm
MG-U74BV2:106011_AT flavin containing monooxygenase 2 mm
MG-U74BV2:115545_AT flavin containing monooxygenase 2 mm
MOE430A:1422905_S_AT flavin containing monooxygenase 2 mm
MOUSE430A_2:1422905_S_AT flavin containing monooxygenase 2 mm
MOUSE430_2:1422905_S_AT flavin containing monooxygenase 2 mm
MOE430A:1422904_AT flavin containing monooxygenase 2 mm
MOUSE430A_2:1422904_AT flavin containing monooxygenase 2 mm
MOUSE430_2:1422904_AT flavin containing monooxygenase 2 mm
MU19KSUBA:TC20942_AT Flavin containing monooxygenase 2, mRNA (cDNA clone MGC:28212 IMAGE:3990305) mm
RG-U34C:AA848675_AT flavin containing monooxygenase 2 rn
RAE230B:1377635_AT flavin containing monooxygenase 2 rn
RAT230_2:1377635_AT flavin containing monooxygenase 2 rn
Gene Ontology
GO Biological Process (view graph)
ID Description Evidence Links
6118 electron transport inferred from electronic annotation QuickGO AmiGO
GO Cellular Component (view graph)
ID Description Evidence Links
5792 microsome inferred from electronic annotation QuickGO AmiGO
GO Molecular Function (view graph)
ID Description Evidence Links
4497 monooxygenase activity inferred from electronic annotation QuickGO AmiGO
4499 dimethylaniline monooxygenase (N-oxide-forming) activity inferred from electronic annotation QuickGO AmiGO
15036 disulfide oxidoreductase activity inferred from electronic annotation QuickGO AmiGO
Protein Similarities
Method ID Description E-Value
blast CAA94291 Hypothetical protein K08C7.2 [Caenorhabditis elegans] ref|NP_501968.2| Flavin-containing MonoOxygenase family member (fmo-1) [Caenorhabditis elegans] emb|CAE46540.1| flavin monooxygenase [Caenorhabditis elegans] 0.0
blast CAB97238 Hypothetical protein Y39A1A.19 [Caenorhabditis elegans] ref|NP_499356.1| Flavin-containing MonoOxygenase family member (fmo-3) [Caenorhabditis elegans] emb|CAE46542.1| flavin monooxygenase [Caenorhabditis elegans] 0.0
blast AAF39901 Flavin-containing monooxygenase family protein 5 [Caenorhabditis elegans] ref|NP_503352.1| Flavin-containing MonoOxygenase family member (fmo-5) [Caenorhabditis elegans] emb|CAE46543.1| flavin monooxygenase [Caenorhabditis elegans] 0.0
Protein Domains
Database ID Description E-Value
Pfam IPR000960 EMBL-EBI Flavin-containing monooxygenase FMO 1.0E-126
Trans Membrane
ID Number Of Domains Domain Boundaries
NP_501968.2 1 510-532
K08C7.2.2 1 510-532
K08C7.2.3 1 510-532
K08C7.2.1 1 510-532
SNAP00000016921 1 510-532
GENEFINDER00000016930 1 510-532
Sequence
Target Sequence 
>C. ELEGANS:191850_S_AT
aagtcgtcgacatactattcaagtggattatgtcgattatattgaagaactcgcgaaaat
gattggagccgacttggacatgaagaaactttggaaagaggacccatggctagcttacaa
ggtatactttggtccatgtgttccgtatatttatcgtttgaaaggcccacataaatggaa
taatgcaagagatgcaattatgtcagttgatgaaagagttcttatggtaaccaaaatata
tttaatccgttcgttcaaaaatgaatttcaggccacgaacgatcacgcacaagtggctcc
tgactatacattgctgtacatcgttggatta

BLASTn GenBank NR
Probe Info
Probe Sequence(5'-3') Probe X Probe Y Probe Interrogation
Position 		Strandedness
AAGTCGTCGACATACTATTCAAGTG 84 159 1290 Antisense
GAACTCGCGAAAATGATTGGAGCCG 582 347 1336 Antisense
GATTGGAGCCGACTTGGACATGAAG 6 435 1350 Antisense
GAAAGAGGACCCATGGCTAGCTTAC 566 355 1383 Antisense
GGACCCATGGCTAGCTTACAAGGTA 558 523 1389 Antisense
GGTATACTTTGGTCCATGTGTTCCG 309 505 1410 Antisense
GGTCCATGTGTTCCGTATATTTATC 478 501 1420 Antisense
ATTTATCGTTTGAAAGGCCCACATA 408 15 1438 Antisense
CGAACGATCACGCACAAGTGGCTCC 421 253 1565 Antisense
TGGCTCCTGACTATACATTGCTGTA 499 545 1583 Antisense
TACATTGCTGTACATCGTTGGATTA 658 641 1596 Antisense
Sequence Source Affymetrix Proprietary Database