[Home] | [Total List]

[191848_at] dihydrolipoamide dehydrogenase

Description LLC1.3 /REP_DB=WormBase Gene ID /WP=CE16262 /TR=O17953 /GB=CAB05249.1 /SUBMIT=HINXTON /CHR=4 /FEA=Sanger Annotation /DEF=dihydrolipoamide dehydrogenase
Cluster 6grp_highest_10_10 > 20      6grp_high1_10_10 > 12      4grp_highest_8_8 > 33      4grp_high_8_8 > 58      6grp_highest_nonorm > 12      6grp_total > 23      4grp_total > 61      6grp_highest_sub > De      6grp_high1_sub > De      6grp_total_sub > Decrease      

Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 1535
1 2 3 4 range
A 2423.3
(3)
P 		1896.6
(0.6)
P 		2413.2
(3)
P 		1100.7
(-3)
P 		1323
B 2274.7
(3)
P 		1987
(1.7)
P 		2264.2
(3)
P 		895.1
(-3)
P 		1380
C 2373.3
(2.8)
P 		2258.3
(2.3)
P 		2425.7
(3)
P 		890.6
(-3)
P 		1535
avr 2357.1
(3) 		2047.3
(1.6) 		2367.7
(3) 		962.1
(-3) 		1406

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 2706
1 2 3 4 5 6 range
A 1617
(-1.3)
P 		2745.8
(3)
P 		1457.3
(-1.9)
P 		1936.9
(-0.1)
P 		1505.4
(-1.8)
P 		1183.8
(-3)
P 		1562
B 2075.5
(3)
P 		1876.9
(2)
P 		1919.8
(2.2)
P 		1675.4
(0.9)
P 		1705.5
(1)
P 		940.1
(-3)
P 		1135
C 3570.2
(3)
P 		1706.7
(-1.1)
P 		2835.1
(1.4)
P 		1395.4
(-1.8)
P 		1749.1
(-1)
P 		864.4
(-3)
P 		2706
avr 2420.9
(3) 		2109.8
(1.7) 		2070.7
(1.5) 		1669.2
(-0.2) 		1653.3
(-0.2) 		996.1
(-3) 		1425
No Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 732
1 2 3 4 range
A 882.3
(3)
P 		411.7
(-0.9)
P 		630.9
(0.9)
P 		161.1
(-3)
P 		721
B 725.4
(3)
P 		490.7
(0.4)
P 		524.7
(0.7)
P 		190.8
(-3)
P 		535
C 785.6
(2.5)
P 		649.3
(1.3)
P 		845.4
(3)
P 		150.2
(-3)
P 		695
avr 797.8
(3) 		517.2
(0.3) 		667
(1.8) 		167.4
(-3) 		630

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 1043
1 2 3 4 5 6 range
A 298.1
(-2.9)
P 		976.5
(3)
P 		317.4
(-2.7)
P 		491.2
(-1.2)
P 		454.3
(-1.6)
P 		288.2
(-3)
P 		688
B 722.2
(3)
P 		624.8
(1.4)
P 		466.2
(-1.1)
P 		443.8
(-1.5)
P 		692.9
(2.5)
P 		350.6
(-3)
P 		372
C 1323.3
(3)
P 		520.8
(-1.6)
P 		721.6
(-0.5)
P 		280.6
(-3)
P 		566
(-1.4)
P 		289.4
(-2.9)
P 		1043
avr 781.2
(3) 		707.4
(2.1) 		501.7
(-0.6) 		405.2
(-1.8) 		571.1
(0.3) 		309.4
(-3) 		472
NetAffx Links Cluster Members
Consensus/Exemplar
GeneChip Array Information
Probe Set ID 191848_at
GeneChip Array C. elegans Genome Array
Organism Common Name Nematode
Probe Design Information
Transcript ID(Array Design) affy.Ce.8545
Sequence Type Exemplar sequence
Representative Public ID LLC1.3 NCBI
Target Description LLC1.3 /REP_DB=WormBase Gene ID /WP=CE16262 /TR=O17953 /GB=CAB05249.1 /SUBMIT=HINXTON /CHR=4 /FEA=Sanger Annotation /DEF=dihydrolipoamide dehydrogenase
Cluster Evidence This cluster is supported by a Sanger Annotation.
Annotation Method Description
Annotation Description This probe set was annotated using the Matching Probes based pipeline to a RefSeq identifier using 1 transcript(s).
Annotation Grade This is a grade A annotation.
Annotation Transcript Cluster (# of Matching Probes) NM_070352(10)
Transcript Assignments
Representative
Transcript		 Description Matching Probes Related Probesets by Grade
NM_070352 NCBI Caenorhabditis elegans LLC1.3 (LLC1.3) mRNA, complete cds. 10/11 None
SNAP00000039833 ENSEMBL cdna:SNAP chromosome:CEL140:IV:14464489:14467578:1 10/11 None
GENEFINDER00000039837 ENSEMBL cdna:GeneFinder chromosome:CEL140:IV:14464489:14468772:1 10/11 None
LLC1.3.2 ENSEMBL cdna:known chromosome:CEL140:IV:14464480:14469098:1 gene:LLC1.3 10/11 None
LLC1.3.1 ENSEMBL cdna:known chromosome:CEL140:IV:14464484:14469098:1 gene:LLC1.3 11/11 None
Annotation Notes
There are no noteworthy cross hybridizing mRNAs found for this probe set.
Genomic Alignment of Consensus/Exemplar Sequence
Assembly Wormbase March 2004
Alignment(s)
Position Identity Coverage Cytoband
chrIV:14464494-14468778(+) 100.0 100.0
Public Domain and Genome References
Gene Title dihydrolipoamide dehydrogenase
Ensembl LLC1.3
Entrez Gene 178387 Entrez gene
SwissProt O17953 EMBL-EBI
WormBase CE31971 Wormbase
Functional Annotations
Ortholog
ID Title Organism
ATH1-121501:260730_AT dihydrolipoamide dehydrogenase 1, mitochondrial / lipoamide dehydrogenase 1 (MTLPD1) at
CANINE:1582408_AT dihydrolipoamide dehydrogenase (E3 component of pyruvate dehydrogenase complex, 2-oxo-glutarate complex, branched chain keto acid dehydrogenase complex) cfa
CANINE_2:CFA.862.1.S1_S_AT dihydrolipoamide dehydrogenase (E3 component of pyruvate dehydrogenase complex, 2-oxo-glutarate complex, branched chain keto acid dehydrogenase complex) cfa
DROSOPHILA_2:1641291_AT dm
DROSGENOME1:141356_AT dm
HG-U133A:209095_AT dihydrolipoamide dehydrogenase (E3 component of pyruvate dehydrogenase complex, 2-oxo-glutarate complex, branched chain keto acid dehydrogenase complex) hs
HG-U133_PLUS_2:209095_AT dihydrolipoamide dehydrogenase (E3 component of pyruvate dehydrogenase complex, 2-oxo-glutarate complex, branched chain keto acid dehydrogenase complex) hs
HG-FOCUS:209095_AT dihydrolipoamide dehydrogenase (E3 component of pyruvate dehydrogenase complex, 2-oxo-glutarate complex, branched chain keto acid dehydrogenase complex) hs
HG-U133A_2:209095_AT dihydrolipoamide dehydrogenase (E3 component of pyruvate dehydrogenase complex, 2-oxo-glutarate complex, branched chain keto acid dehydrogenase complex) hs
HG-U95AV2:36163_AT dihydrolipoamide dehydrogenase (E3 component of pyruvate dehydrogenase complex, 2-oxo-glutarate complex, branched chain keto acid dehydrogenase complex) hs
HUGENEFL:L13761_RNA1_AT dihydrolipoamide dehydrogenase (E3 component of pyruvate dehydrogenase complex, 2-oxo-glutarate complex, branched chain keto acid dehydrogenase complex) hs
U133_X3P:G181574_3P_AT dihydrolipoamide dehydrogenase (E3 component of pyruvate dehydrogenase complex, 2-oxo-glutarate complex, branched chain keto acid dehydrogenase complex) hs
HG-U133_PLUS_2:230426_AT Dihydrolipoamide dehydrogenase (E3 component of pyruvate dehydrogenase complex, 2-oxo-glutarate complex, branched chain keto acid dehydrogenase complex) hs
HG-U133B:230426_AT Dihydrolipoamide dehydrogenase (E3 component of pyruvate dehydrogenase complex, 2-oxo-glutarate complex, branched chain keto acid dehydrogenase complex) hs
HG-U95D:78053_AT Dihydrolipoamide dehydrogenase (E3 component of pyruvate dehydrogenase complex, 2-oxo-glutarate complex, branched chain keto acid dehydrogenase complex) hs
HG-U95D:85745_AT Dihydrolipoamide dehydrogenase (E3 component of pyruvate dehydrogenase complex, 2-oxo-glutarate complex, branched chain keto acid dehydrogenase complex) hs
U133_X3P:HS.74635.1.A1_3P_AT Dihydrolipoamide dehydrogenase (E3 component of pyruvate dehydrogenase complex, 2-oxo-glutarate complex, branched chain keto acid dehydrogenase complex) hs
MOE430A:1423159_AT dihydrolipoamide dehydrogenase mm
MOUSE430_2:1423159_AT dihydrolipoamide dehydrogenase mm
MOUSE430A_2:1423159_AT dihydrolipoamide dehydrogenase mm
MU11KSUBA:U73445_S_AT dihydrolipoamide dehydrogenase mm
MG-U74AV2:97502_AT dihydrolipoamide dehydrogenase mm
MG-U74CV2:169843_AT dihydrolipoamide dehydrogenase mm
MOE430B:1433263_AT dihydrolipoamide dehydrogenase mm
MOUSE430_2:1433263_AT dihydrolipoamide dehydrogenase mm
MU19KSUBC:TC36486_I_AT Dihydrolipoamide dehydrogenase, mRNA (cDNA clone MGC:5874 IMAGE:3589344) mm
RG-U34B:RC_AI045119_AT dihydrolipoamide dehydrogenase rn
RG-U34C:RC_AI176696_AT dihydrolipoamide dehydrogenase rn
RAE230A:1373016_AT dihydrolipoamide dehydrogenase rn
RAT230_2:1373016_AT dihydrolipoamide dehydrogenase rn
YEAST_2:1772674_AT Dihydrolipoamide dehydrogenase, the lipoamide dehydrogenase component (E3) of the pyruvate dehydrogenase and 2-oxoglutarate dehydrogenase multi-enzyme complexes Sc
Gene Ontology
GO Biological Process (view graph)
ID Description Evidence Links
6096 glycolysis inferred from electronic annotation QuickGO AmiGO
6118 electron transport inferred from electronic annotation QuickGO AmiGO
GO Cellular Component (view graph)
ID Description Evidence Links
5737 cytoplasm inferred from electronic annotation QuickGO AmiGO
GO Molecular Function (view graph)
ID Description Evidence Links
4148 dihydrolipoyl dehydrogenase activity inferred from electronic annotation QuickGO AmiGO
15036 disulfide oxidoreductase activity inferred from electronic annotation QuickGO AmiGO
16491 oxidoreductase activity inferred from electronic annotation QuickGO AmiGO
46872 metal ion binding inferred from electronic annotation QuickGO AmiGO
Protein Similarities
Method ID Description E-Value
blast CAB05249 Hypothetical protein LLC1.3 [Caenorhabditis elegans] ref|NP_502753.2| LLC1.3 [Caenorhabditis elegans] 0.0
blast CAE73952 Hypothetical protein CBG21577 [Caenorhabditis briggsae] 0.0
blast AAD30450 lipoamide dehydrogenase [Ascaris suum] 0.0
Protein Domains
Database ID Description E-Value
Pfam IPR004099 EMBL-EBI Pyridine nucleotide-disulphide oxidoreductase dimerisation domain 2.4E-66
Pfam IPR001327 EMBL-EBI FAD-dependent pyridine nucleotide-disulphide oxidoreductase 3.1E-103
Pfam IPR004099 EMBL-EBI Pyridine nucleotide-disulphide oxidoreductase dimerisation domain 2.8E-58
Sequence
Target Sequence 
>C. ELEGANS:191848_AT
tatgggagcctcgcagaacggatcaaccatcactgttgaggtcgaaggagccaaggatgg
aaagaaacagactctcgaatgcgacacgctcctcgtctcagtcggacgccgcccatacac
cgaaggtctcggactctcgaacgttcaaatcgatttggacaatcgtggacgtgttccagt
caacgaacgcttccagactaaagttccatcaatcttcgccatcggtgacgtcatcgaggg
tccaatgctcgcgcacaaggccgaggacgaaggaattctgtgtgttgagggaatcgccgg
aggaccaggagtcgcctacaaaatcggaaaattcccattcgtcgccaactctcgtgccaa
gaccaacaatgatcaggagggtttcgtgaaagttttggctgataaacagactgatcgtat
gctgggagttcatattattggaccaaacgccggagaaatgatcgccgaagccacgttggc
aat

BLASTn GenBank NR
Probe Info
Probe Sequence(5'-3') Probe X Probe Y Probe Interrogation
Position 		Strandedness
TATGGGAGCCTCGCAGAACGGATCA 521 653 804 Antisense
AACAGACTCTCGAATGCGACACGCT 546 135 869 Antisense
CGCCCATACACCGAAGGTCTCGGAC 113 257 913 Antisense
GTCTCGGACTCTCGAACGTTCAAAT 122 467 929 Antisense
TCCAGTCAACGAACGCTTCCAGACT 227 591 978 Antisense
CTAAAGTTCCATCAATCTTCGCCAT 682 225 1001 Antisense
GTCATCGAGGGTCCAATGCTCGCGC 506 463 1033 Antisense
TGCTCGCGCACAAGGCCGAGGACGA 97 579 1049 Antisense
GTGTTGAGGGAATCGCCGGAGGACC 676 481 1085 Antisense
GAGGACCAGGAGTCGCCTACAAAAT 120 405 1103 Antisense
TGATCGCCGAAGCCACGTTGGCAAT 375 563 1262 Antisense
Sequence Source Affymetrix Proprietary Database