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[191843_s_at] Cuticlin family

Description D2045.6 /REP_DB=WormBase Gene ID /WP=CE00606 /GEN=cul-1 /TR=SW:Q17389 /GB=CAA84695.1 /SUBMIT=HINXTON /CHR=3 /FEA=Sanger Annotation /DEF=Cuticlin family
Cluster 6grp_highest_10_10 > 75      6grp_high1_10_10 > 57      4grp_highest_8_8 > 48      4grp_high_8_8 > 43      6grp_highest_nonorm > 85      6grp_total > 58      4grp_total > 53      6grp_highest_sub > Cu      6grp_cgc > 38      6grp_high1_sub > Cu      6grp_cgc_sub > Da      6grp_total_sub > Cup      

Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 304
1 2 3 4 range
A 891.2
(2.4)
P 		917.6
(3)
P 		798.5
(0.2)
P 		659.9
(-3)
P 		258
B 914.4
(0.7)
P 		833.9
(-3)
P 		964.3
(3)
P 		915.8
(0.8)
P 		130
C 838.5
(1)
P 		875.3
(3)
P 		762.5
(-3)
P 		871.5
(2.8)
P 		113
avr 881.4
(3) 		875.6
(2.5) 		841.8
(-0.6) 		815.7
(-3) 		66

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 578
1 2 3 4 5 6 range
A 764.6
(-1.2)
P 		733.8
(-1.6)
P 		596.5
(-3)
P 		740.2
(-1.5)
P 		641.1
(-2.5)
P 		1171.9
(3)
P 		575
B 792.5
(1.2)
P 		628.9
(-2.3)
P 		741.2
(0.1)
P 		645.6
(-1.9)
P 		593.7
(-3)
P 		878.3
(3)
P 		285
C 881.3
(0.8)
P 		665
(-3)
P 		774.7
(-1.1)
P 		701.8
(-2.4)
P 		794.5
(-0.7)
P 		1005.9
(3)
P 		341
avr 812.8
(-0.6) 		675.9
(-3) 		704.1
(-2.5) 		695.9
(-2.6) 		676.4
(-3) 		1018.7
(3) 		343
No Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 228
1 2 3 4 range
A 324.5
(3)
P 		199.2
(-0.3)
P 		208.8
(-0)
P 		96.6
(-3)
P 		228
B 291.6
(3)
P 		206
(-2.3)
P 		223.5
(-1.2)
P 		195.2
(-3)
P 		96
C 277.6
(3)
P 		251.7
(1.8)
P 		265.7
(2.5)
P 		146.9
(-3)
P 		131
avr 297.9
(3) 		219
(-0.1) 		232.7
(0.4) 		146.2
(-3) 		152

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 207
1 2 3 4 5 6 range
A 140.9
(-2.6)
P 		261
(2.1)
P 		129.9
(-3)
P 		187.7
(-0.8)
P 		193.5
(-0.5)
P 		285.3
(3)
P 		155
B 275.7
(1)
P 		209.3
(-1.5)
P 		180
(-2.7)
P 		171
(-3)
P 		241.2
(-0.3)
P 		327.5
(3)
P 		157
C 326.7
(2.7)
P 		202.9
(-1.1)
P 		197.2
(-1.3)
P 		141.1
(-3)
P 		257.1
(0.6)
P 		336.7
(3)
P 		196
avr 247.8
(0.3) 		224.4
(-0.7) 		169
(-2.9) 		166.6
(-3) 		230.6
(-0.4) 		316.5
(3) 		150
NetAffx Links Cluster Members
Consensus/Exemplar
Group Members
GeneChip Array Information
Probe Set ID 191843_s_at
GeneChip Array C. elegans Genome Array
Organism Common Name Nematode
Probe Design Information
Transcript ID(Array Design) affy.Ce.6066
Sequence Type Exemplar sequence
Representative Public ID D2045.6 NCBI
Target Description D2045.6 /REP_DB=WormBase Gene ID /WP=CE00606 /GEN=cul-1 /TR=SW:Q17389 /GB=CAA84695.1 /SUBMIT=HINXTON /CHR=3 /FEA=Sanger Annotation /DEF=Cuticlin family
Cluster Evidence This cluster is supported by a Sanger Annotation.
Annotation Method Description
Annotation Description This probe set was annotated using the Matching Probes based pipeline to a RefSeq identifier using 1 transcript(s).
Annotation Grade This is a grade A annotation.
Annotation Transcript Cluster (# of Matching Probes) NM_066908(11)
Transcript Assignments
Representative
Transcript		 Description Matching Probes Related Probesets by Grade
NM_066908 NCBI Caenorhabditis elegans CULlin family member (cul-1) (cul-1) mRNA, complete cds. 11/11 A 
SNAP00000022542 ENSEMBL cdna:SNAP chromosome:CEL140:III:10471119:10474765:1 11/11 None
GENEFINDER00000022551 ENSEMBL cdna:GeneFinder chromosome:CEL140:III:10471119:10474765:1 11/11 None
D2045.6 ENSEMBL cdna:known chromosome:CEL140:III:10471118:10475481:1 gene:D2045.6 11/11 A 
Annotation Notes
There are no noteworthy cross hybridizing mRNAs found for this probe set.
Genomic Alignment of Consensus/Exemplar Sequence
Assembly Wormbase March 2004
Alignment(s)
Position Identity Coverage Cytoband
chrIII:10471138-10474761(+) 100.0 100.0
Public Domain and Genome References
Gene Title Cuticlin family
Gene Symbol cul-1
Ensembl D2045.6
Entrez Gene 176466 Entrez gene
SwissProt Q17389 EMBL-EBI
WormBase CE29089 Wormbase
Functional Annotations
Ortholog
ID Title Organism
ATGENOME1:19642_AT cullin family protein at
ATH1-121501:255441_AT cullin family protein at
CANINE:1583915_AT similar to Cullin-1 (CUL-1) cfa
CANINE_2:CFA.18465.1.S1_AT similar to Cullin-1 (CUL-1) cfa
CANINE_2:CFA.20001.1.S1_S_AT similar to Cullin-1 (CUL-1) cfa
CANINE_2:CFA.6461.1.A1_AT similar to Cullin-1 (CUL-1) cfa
CANINE_2:CFAAFFX.6137.1.S1_AT similar to Cullin-1 (CUL-1) cfa
DROSOPHILA_2:1624407_S_AT lin-19-like dm
DROSGENOME1:153960_AT lin-19-like dm
CHICKEN:GGA.16583.1.S1_AT similar to Cullin homolog 1 (CUL-1) gga
CHICKEN:GGAAFFX.23892.1.S1_S_AT similar to Cullin homolog 1 (CUL-1) gga
HG-U95AV2:39724_S_AT cullin 1 hs
HG-U133_PLUS_2:207614_S_AT cullin 1 hs
HG-U133A:207614_S_AT cullin 1 hs
HG-FOCUS:207614_S_AT cullin 1 hs
HG-U133A_2:207614_S_AT cullin 1 hs
HUGENEFL:U58087_AT cullin 1 hs
U133_X3P:G4503160_3P_A_AT cullin 1 hs
HG-U95AV2:39723_AT cullin 1 hs
HG-U95E:67544_AT cullin 1 hs
U133_X3P:HS.144996.0.S1_3P_AT Cullin 1 hs
HG-U133_PLUS_2:238509_AT Cullin 1 hs
HG-U133B:238509_AT Cullin 1 hs
HG-U95E:82701_AT Cullin 1 hs
HG-U133_PLUS_2:243286_AT Cullin 1 hs
HG-U133B:243286_AT Cullin 1 hs
HG-U95B:55809_AT Cullin 1 hs
HU35KSUBB:RC_AA028139_AT Cullin 1 hs
U133_X3P:HS.140498.0.A1_3P_AT Cullin 1 hs
MOE430A:1448174_AT cullin 1 mm
MOUSE430_2:1448174_AT cullin 1 mm
MOUSE430A_2:1448174_AT cullin 1 mm
MG-U74AV2:94002_AT cullin 1 mm
MG-U74BV2:164497_R_AT cullin 1 mm
MOE430B:1440547_AT Cullin 1, mRNA (cDNA clone MGC:35976 IMAGE:2812400) mm
MOUSE430_2:1440547_AT Cullin 1, mRNA (cDNA clone MGC:35976 IMAGE:2812400) mm
MOUSE430_2:1459516_AT Cullin 1, mRNA (cDNA clone MGC:35976 IMAGE:2812400) mm
MOE430B:1459516_AT Cullin 1, mRNA (cDNA clone MGC:35976 IMAGE:2812400) mm
MG-U74CV2:167458_R_AT Cullin 1, mRNA (cDNA clone MGC:35976 IMAGE:2812400) mm
MU19KSUBA:TC22941_AT Cullin 1, mRNA (cDNA clone MGC:35976 IMAGE:2812400) mm
MU19KSUBB:TC34028_AT Cullin 1, mRNA (cDNA clone MGC:35976 IMAGE:2812400) mm
RG-U34B:RC_AI010362_AT cullin 1 (predicted) rn
RAE230A:1388855_AT cullin 1 (predicted) rn
RAT230_2:1388855_AT cullin 1 (predicted) rn
Gene Ontology
GO Biological Process (view graph)
ID Description Evidence Links
7049 cell cycle inferred from electronic annotation QuickGO AmiGO
GO Cellular Component (view graph)
ID Description Evidence Links
5829 cytosol non-traceable author statement QuickGO AmiGO
Protein Similarities
Method ID Description E-Value
blast CAA84695 Hypothetical protein D2045.6 [Caenorhabditis elegans] ref|NP_499309.1| CULlin family member (cul-1) [Caenorhabditis elegans] sp|Q17389|CUL1_CAEEL Cullin-1 (Abnormal cell lineage 19 protein) gb|AAC47120.1| CUL-1 0.0
blast T20365 hypothetical protein D2045.6 - Caenorhabditis elegans 0.0
blast CAE71464 Hypothetical protein CBG18382 [Caenorhabditis briggsae] 0.0
Protein Domains
Database ID Description E-Value
scop a.4.5.SCF ubiquitin ligase complex WHB domain All alpha proteins; DNA/RNA-binding 3-helical bundle; "Winged helix" DNA-binding domain; SCF ubiquitin ligase complex WHB domain 4.00000018680441E-34
Pfam IPR001373 EMBL-EBI Cullin 1.0E-126
Sequence
Target Sequence 
>C. ELEGANS:191843_S_AT
agaagttcaatggacgtcggctcacgtgggtttactcgcagagtcgtggagagatcactt
ctacagcttttcccaagaaatatgtgtttactgccacaactgctcaaatgtgcacaatgc
ttttgttcaacgaacaggactcgtacactgtcgaacaaatcgccgctgccacaaaaatgg
acgaaaagtcagcaccagccattgtcggctctctcatcaaaaatcttgtgctcaaagcgg
acacagaactccaaaaagaggatgaagtaccgatgacggcgaccgtaagcctcaacaaag
cctacatgaacaagaaagttcgtgtcgatttgtcaaaattcacgatgaagcaggacgccg
tgcgtgatacggaaaatgtgcagaaaaatgttgaggaggatcggaagagcgtgattagtg
cttgcatcgtaagaatcatgaaaactcgcaaacgtgtacagcatcagcagcttatgacag
aggtgatcacacaactttccggtcgattca

BLASTn GenBank NR
Probe Info
Probe Sequence(5'-3') Probe X Probe Y Probe Interrogation
Position 		Strandedness
AGAAGTTCAATGGACGTCGGCTCAC 342 75 1718 Antisense
GCTCACGTGGGTTTACTCGCAGAGT 295 301 1737 Antisense
GTGGAGAGATCACTTCTACAGCTTT 305 491 1763 Antisense
ATGTGTTTACTGCCACAACTGCTCA 659 49 1799 Antisense
ACACTGTCGAACAAATCGCCGCTGC 515 109 1862 Antisense
CGAAAAGTCAGCACCAGCCATTGTC 260 253 1899 Antisense
CATTGTCGGCTCTCTCATCAAAAAT 379 217 1917 Antisense
TGACGGCGACCGTAAGCCTCAACAA 231 569 1991 Antisense
GAAGCAGGACGCCGTGCGTGATACG 435 341 2064 Antisense
ACTCGCAAACGTGTACAGCATCAGC 367 91 2161 Antisense
ATCACACAACTTTCCGGTCGATTCA 558 25 2203 Antisense
Sequence Source Affymetrix Proprietary Database