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[191818_at] 7TM chemoreceptor, srx family

Description T07H8.3 /REP_DB=WormBase Gene ID /WP=CE18224 /TR=O61895 /GB=AAC17676.1 /SUBMIT=ST.LOUIS /CHR=5 /FEA=Sanger Annotation /DEF=seven transmembrane receptor
Cluster 6grp_total > 90      4grp_total > 27      6grp_cgc > 96      

Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 113
1 2 3 4 range
A 23.9
(-3)
A 		54.2
(-0.6)
A 		85.4
(1.8)
A 		100.5
(3)
A 		77
B 65.4
(-0.6)
A 		79.5
(3)
A 		55.7
(-3)
A 		60.4
(-1.8)
A 		24
C 64.9
(-0.8)
A 		136.4
(3)
A 		24.2
(-3)
A 		132.8
(2.8)
P 		112
avr 51.4
(-3) 		90
(2) 		55.1
(-2.5) 		97.9
(3) 		47

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 95
1 2 3 4 5 6 range
A 43.7
(1.9)
A 		24.2
(-0.7)
A 		23.9
(-0.7)
A 		6.4
(-3)
A 		16.3
(-1.7)
A 		52.1
(3)
A 		46
B 69.3
(1)
A 		6.8
(-3)
A 		31.3
(-1.4)
A 		101.3
(3)
A 		63.7
(0.6)
A 		23.6
(-1.9)
A 		95
C 50.2
(-0.4)
A 		53.1
(-0.2)
A 		14.6
(-3)
A 		96.7
(3)
A 		36.7
(-1.4)
A 		48
(-0.6)
A 		82
avr 54.4
(1.2) 		28
(-2.4) 		23.3
(-3) 		68.1
(3) 		38.9
(-0.9) 		41.2
(-0.6) 		45
No Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 31
1 2 3 4 range
A 8.7
(-3)
A 		11.8
(-1.6)
A 		22.3
(3)
A 		14.7
(-0.4)
A 		14
B 20.8
(3)
A 		19.6
(2.1)
A 		12.9
(-3)
A 		12.9
(-3)
A 		8
C 21.5
(-0.4)
A 		39.2
(3)
A 		8.4
(-3)
A 		22.4
(-0.3)
P 		31
avr 17
(-1.3) 		23.5
(3) 		14.5
(-3) 		16.7
(-1.5) 		9

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 25
1 2 3 4 5 6 range
A 8.1
(0.5)
A 		8.6
(0.8)
A 		5.2
(-1.1)
A 		1.6
(-3)
A 		4.9
(-1.2)
A 		12.7
(3)
A 		11
B 24.1
(2.3)
A 		2.2
(-3)
A 		7.6
(-1.7)
A 		26.8
(3)
A 		25.9
(2.8)
A 		8.8
(-1.4)
A 		25
C 18.6
(2.7)
A 		16.2
(1.8)
A 		3.7
(-3)
A 		19.4
(3)
A 		11.9
(0.1)
A 		16.1
(1.7)
A 		16
avr 16.9
(3) 		9
(-1.2) 		5.5
(-3) 		15.9
(2.5) 		14.2
(1.6) 		12.5
(0.7) 		11
NetAffx Links Cluster Members
Consensus/Exemplar
GeneChip Array Information
Probe Set ID 191818_at
GeneChip Array C. elegans Genome Array
Organism Common Name Nematode
Probe Design Information
Transcript ID(Array Design) affy.Ce.12425
Sequence Type Exemplar sequence
Representative Public ID T07H8.3 NCBI
Target Description T07H8.3 /REP_DB=WormBase Gene ID /WP=CE18224 /TR=O61895 /GB=AAC17676.1 /SUBMIT=ST.LOUIS /CHR=5 /FEA=Sanger Annotation /DEF=seven transmembrane receptor
Cluster Evidence This cluster is supported by a Sanger Annotation.
Annotation Method Description
Annotation Description This probe set was annotated using the Matching Probes based pipeline to a RefSeq identifier using 1 transcript(s).
Annotation Grade This is a grade A annotation.
Annotation Transcript Cluster (# of Matching Probes) NM_072360(11)
Transcript Assignments
Representative
Transcript		 Description Matching Probes Related Probesets by Grade
NM_072360 NCBI Caenorhabditis elegans Serpentine Receptor, class X family member (srx-59) (srx-59) mRNA, complete cds. 11/11 None
GENEFINDER00000037168 ENSEMBL cdna:GeneFinder chromosome:CEL140:V:6974460:6975742:1 11/11 None
T07H8.3 ENSEMBL cdna:known chromosome:CEL140:V:6974460:6975742:1 gene:T07H8.3 11/11 None
Annotation Notes
There are no noteworthy cross hybridizing mRNAs found for this probe set.
Genomic Alignment of Consensus/Exemplar Sequence
Assembly Wormbase March 2004
Alignment(s)
Position Identity Coverage Cytoband
chrV:6974460-6975743(+) 100.0 100.0
Public Domain and Genome References
Gene Title 7TM chemoreceptor, srx family
Gene Symbol srx-59
Ensembl T07H8.3
Entrez Gene 188258 Entrez gene
SwissProt O61895 EMBL-EBI
WormBase CE36565 Wormbase
Functional Annotations
Protein Similarities
Method ID Description E-Value
blast NP_504761 Serpentine Receptor, class X family member (srx-59) [Caenorhabditis elegans] gb|AAC17676.2| Serpentine receptor, class x protein 59 [Caenorhabditis elegans] 1.0E-168
blast AAF39928 Serpentine receptor, class x protein 62 [Caenorhabditis elegans] ref|NP_504114.1| Serpentine Receptor, class X family member (srx-62) [Caenorhabditis elegans] 4.0E-80
blast AAB94249 Serpentine receptor, class x protein 64 [Caenorhabditis elegans] ref|NP_504089.2| Serpentine Receptor, class X family member (srx-64) [Caenorhabditis elegans] 3.0E-78
Protein Domains
Trans Membrane
ID Number Of Domains Domain Boundaries
NP_504761.2 7 10-32,53-75,85-107,124-146,176-198,219-241,251-273
T07H8.3 7 10-32,53-75,85-107,124-146,176-198,219-241,251-273
GENEFINDER00000037168 7 10-32,53-75,85-107,124-146,176-198,219-241,251-273
Sequence
Target Sequence 
>C. ELEGANS:191818_AT
ttccttgaacagattcttcgccgtgtggactccatatcgttacaaaacaatgtttagtga
aagaaacacaaaaataataatatttctcatctttattctcactctcggattctcattttc
tttttatgaagtgttgtgctctctggaatataatttgaaaactgggttcttcttcttcac
cgatactccactatgtaatactattggctggtacgcagatttttgtaaatactttaccat
catagtttgcattgtattgatagacattgcaactttgtggaaagtacacacaagtgtcaa
ttcacaaacccaccgaaaaatgtctgctcgtgaaatcaactttctgaagcaaactatttt
tcaaggatttatttttactctagaacttgtgtcttacttcatccttcctgctcatctcac
aaacaaatgggctatctttttcgccacgtcatttgcctgggtagctgtgcatgcactcga
cggattcattataatggtgttcaatccggatgttaaacgttacctattctcttgtggcca
tgcgactctgcacacaagtcaa

BLASTn GenBank NR
Probe Info
Probe Sequence(5'-3') Probe X Probe Y Probe Interrogation
Position 		Strandedness
TTCCTTGAACAGATTCTTCGCCGTG 96 697 309 Antisense
CGCCGTGTGGACTCCATATCGTTAC 161 257 327 Antisense
GAAGTGTTGTGCTCTCTGGAATATA 543 335 436 Antisense
TCTTCACCGATACTCCACTATGTAA 167 617 482 Antisense
CAAACCCACCGAAAAATGTCTGCTC 280 191 613 Antisense
AGAACTTGTGTCTTACTTCATCCTT 616 73 690 Antisense
CTTCCTGCTCATCTCACAAACAAAT 557 219 712 Antisense
AAATGGGCTATCTTTTTCGCCACGT 289 121 733 Antisense
GTGCATGCACTCGACGGATTCATTA 300 481 775 Antisense
TAAACGTTACCTATTCTCTTGTGGC 577 639 822 Antisense
CCATGCGACTCTGCACACAAGTCAA 707 269 846 Antisense
Sequence Source Affymetrix Proprietary Database