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[191815_s_at] guanylate cyclase

Description R01E6.1 /REP_DB=WormBase Gene ID /WP=CE27430 /GEN=gcy-10 /TR=Q21617 /GB=CAA92186.2 /SUBMIT=HINXTON /CHR=X /FEA=Sanger Annotation /DEF=guanylate cyclase
Cluster 6grp_total > 29      4grp_total > 14      6grp_cgc > 02      

Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 90
1 2 3 4 range
A 45.2
(2)
A 		7.8
(-2.9)
A 		6.7
(-3)
A 		53
(3)
A 		46
B 59.4
(0.6)
A 		10
(-3)
A 		10.6
(-3)
A 		91.6
(3)
A 		82
C 58.6
(0.5)
A 		21.7
(-2)
A 		6.4
(-3)
A 		95.9
(3)
A 		90
avr 54.4
(0.9) 		13.2
(-2.6) 		7.9
(-3) 		80.2
(3) 		72

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 58
1 2 3 4 5 6 range
A 15.9
(-1.8)
A 		7.7
(-2.6)
A 		25.3
(-0.8)
A 		4.2
(-3)
A 		62.2
(3)
A 		8.6
(-2.5)
A 		58
B 29.1
(3)
A 		11.1
(-1.6)
A 		7.5
(-2.5)
A 		5.6
(-3)
A 		8.3
(-2.3)
A 		5.5
(-3)
A 		24
C 42.9
(3)
A 		15.5
(-2)
A 		9.9
(-3)
A 		12
(-2.6)
A 		13.1
(-2.4)
A 		13.9
(-2.3)
A 		33
avr 29.3
(3) 		11.4
(-1.9) 		14.2
(-1.1) 		7.3
(-3) 		27.9
(2.6) 		9.3
(-2.5) 		22
No Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 18
1 2 3 4 range
A 16.5
(3)
A 		1.7
(-3)
A 		1.8
(-3)
A 		7.8
(-0.5)
A 		15
B 18.9
(2.8)
A 		2.5
(-3)
A 		2.5
(-3)
A 		19.5
(3)
A 		17
C 19.4
(3)
A 		6.3
(-1.6)
A 		2.2
(-3)
A 		16.2
(1.9)
A 		17
avr 18.3
(3) 		3.5
(-2.5) 		2.2
(-3) 		14.5
(1.6) 		16

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 18
1 2 3 4 5 6 range
A 2.9
(-2.4)
A 		2.8
(-2.4)
A 		5.5
(-1.5)
A 		1.1
(-3)
A 		18.8
(3)
A 		2.1
(-2.7)
A 		18
B 10.1
(3)
A 		3.7
(-1.5)
A 		1.8
(-2.8)
A 		1.5
(-3)
A 		3.4
(-1.7)
A 		2
(-2.7)
A 		9
C 15.9
(3)
A 		4.7
(-2)
A 		2.5
(-3)
A 		2.4
(-3)
A 		4.2
(-2.2)
A 		4.6
(-2)
A 		14
avr 9.6
(3) 		3.7
(-1.5) 		3.3
(-1.8) 		1.7
(-3) 		8.8
(2.4) 		2.9
(-2.1) 		8
NetAffx Links Cluster Members
Consensus/Exemplar
Group Members
GeneChip Array Information
Probe Set ID 191815_s_at
GeneChip Array C. elegans Genome Array
Organism Common Name Nematode
Probe Design Information
Transcript ID(Array Design) affy.Ce.18018
Sequence Type Exemplar sequence
Representative Public ID R01E6.1 NCBI
Target Description R01E6.1 /REP_DB=WormBase Gene ID /WP=CE27430 /GEN=gcy-10 /TR=Q21617 /GB=CAA92186.2 /SUBMIT=HINXTON /CHR=X /FEA=Sanger Annotation /DEF=guanylate cyclase
Cluster Evidence This cluster is supported by a Sanger Annotation.
Annotation Method Description
Annotation Description This probe set was annotated using the Matching Probes based pipeline to a RefSeq identifier using 1 transcript(s).
Annotation Grade This is a grade A annotation.
Annotation Transcript Cluster (# of Matching Probes) NM_077865(11)
Transcript Assignments
Representative
Transcript		 Description Matching Probes Related Probesets by Grade
NM_077865 NCBI Caenorhabditis elegans ODoRant response abnormal family member (odr-1) (odr-1) mRNA, complete cds. 11/11 None
SNAP00000031390 ENSEMBL cdna:SNAP chromosome:CEL140:X:13544741:13550619:-1 10/11 None
GENEFINDER00000031396 ENSEMBL cdna:GeneFinder chromosome:CEL140:X:13544741:13550743:-1 10/11 None
R01E6.1 ENSEMBL cdna:known chromosome:CEL140:X:13545206:13550643:-1 gene:R01E6.1 11/11 None
Annotation Notes
There are no noteworthy cross hybridizing mRNAs found for this probe set.
Genomic Alignment of Consensus/Exemplar Sequence
Assembly Wormbase March 2004
Alignment(s)
Position Identity Coverage Cytoband
chrX:13545205-13550743(-) 100.0 100.0
Public Domain and Genome References
Gene Title guanylate cyclase
Gene Symbol odr-1
Ensembl R01E6.1
Entrez Gene 181479 Entrez gene
SwissProt Q21617 EMBL-EBI
WormBase CE27430 Wormbase
Functional Annotations
Gene Ontology
GO Biological Process (view graph)
ID Description Evidence Links
6468 protein amino acid phosphorylation inferred from electronic annotation QuickGO AmiGO
7242 intracellular signaling cascade inferred from electronic annotation QuickGO AmiGO
GO Molecular Function (view graph)
ID Description Evidence Links
4383 guanylate cyclase activity inferred from electronic annotation QuickGO AmiGO
4672 protein kinase activity inferred from electronic annotation QuickGO AmiGO
4674 protein serine/threonine kinase activity inferred from electronic annotation QuickGO AmiGO
5524 ATP binding inferred from electronic annotation QuickGO AmiGO
Protein Similarities
Method ID Description E-Value
blast CAA92186 Hypothetical protein R01E6.1 [Caenorhabditis elegans] ref|NP_510266.3| ODoRant response abnormal family member (odr-1) [Caenorhabditis elegans] 0.0
blast AAF68380 guanylyl cyclase [Caenorhabditis elegans] 0.0
blast CAB06040 Hypothetical protein C06A12.4 [Caenorhabditis elegans] ref|NP_503110.1| Guanylyl CYclase family member (gcy-27) [Caenorhabditis elegans] 0.0
Protein Domains
Database ID Description E-Value
Pfam IPR000719 EMBL-EBI Protein kinase 9.3E-9
Pfam IPR001054 EMBL-EBI Guanylate cyclase 2.4E-55
Pfam IPR000719 EMBL-EBI Protein kinase 9.3E-9
Pfam IPR001054 EMBL-EBI Guanylate cyclase 1.1E-59
Pfam IPR000719 EMBL-EBI Protein kinase 9.3E-9
Pfam IPR001054 EMBL-EBI Guanylate cyclase 1.1E-59
Trans Membrane
ID Number Of Domains Domain Boundaries
NP_510266.3 1 406-428
R01E6.1 1 406-428
SNAP00000031390 1 246-268
GENEFINDER00000031396 1 463-485
Sequence
Target Sequence 
>C. ELEGANS:191815_S_AT
aaatggactcataatgccaccgagaagctatgaatcggcaaccgttatgtttgttcaaat
ttgtgatttcaatgcactaatgaaacgaagttctcccgaacaggtaattgcatttcttaa
tgatatttatgatcaatttgacactgtaatcaagagacacgatgcttataaagttgaaac
aacaggggaaacttacatggttgcttctggtgtcccgcacgaaaacgaaggaaggcatat
atttgaagtggccgagataagtctagagatccgagaaatatcgtacatttatgttttaca
acatgacaagaactataaactccggataagaattggttttcacgccgggccaattgcagc
aggtgtgattggaatccgatcaccccggtattgcctcttcggcgacactgtcaattttgc
atccagaatgcaatcgaattgtccgccaaatcaaattcaaactagtgaaataactgcgag
acttttatttgattcacatgaatacaaatttgtgaagagaggaattgtacatgtcaaagg
gaaaggtaatgcggcgcgtttg

BLASTn GenBank NR
Probe Info
Probe Sequence(5'-3') Probe X Probe Y Probe Interrogation
Position 		Strandedness
AAATGGACTCATAATGCCACCGAGA 424 121 2517 Antisense
AATCGGCAACCGTTATGTTTGTTCA 423 169 2549 Antisense
AGTTCTCCCGAACAGGTAATTGCAT 560 13 2605 Antisense
ACTTACATGGTTGCTTCTGGTGTCC 675 101 2707 Antisense
TTCTGGTGTCCCGCACGAAAACGAA 288 693 2721 Antisense
GATAAGAATTGGTTTTCACGCCGGG 481 421 2841 Antisense
CCGGGCCAATTGCAGCAGGTGTGAT 540 265 2861 Antisense
GTGTGATTGGAATCCGATCACCCCG 97 487 2879 Antisense
GGCGACACTGTCAATTTTGCATCCA 45 543 2917 Antisense
TGCAATCGAATTGTCCGCCAAATCA 268 577 2945 Antisense
AGGGAAAGGTAATGCGGCGCGTTTG 510 55 3054 Antisense
Sequence Source Affymetrix Proprietary Database