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[191808_s_at] protein phosphatase

Description ZK1251.5 /REP_DB=WormBase Gene ID /WP=CE03852 /TR=Q23433 /GB=CAA92501.1 /SUBMIT=HINXTON /CHR=4 /FEA=Sanger Annotation /DEF=protein-tyrosine phosphatase
Cluster 6grp_total > 78      4grp_total > 04      6grp_total_sub > Increase      6grp_rule_based > S6      

Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 53
1 2 3 4 range
A 14.8
(2.5)
A 		4.1
(-2.9)
A 		15.8
(3)
A 		4
(-3)
A 		12
B 19.4
(-1.4)
A 		10.2
(-2.5)
A 		6.7
(-3)
A 		52.9
(3)
A 		46
C 19.7
(-1.4)
A 		13.5
(-2.2)
A 		6.7
(-3)
A 		56.8
(3)
A 		50
avr 18
(-1.2) 		9.3
(-3) 		9.7
(-2.9) 		37.9
(3) 		29

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 111
1 2 3 4 5 6 range
A 23.6
(-1.8)
A 		26.4
(-1.7)
A 		17.4
(-2.2)
A 		3.3
(-3)
A 		52.7
(-0.1)
A 		107
(3)
P 		104
B 17.7
(-2.7)
A 		13.4
(-3)
A 		33.4
(-1.7)
A 		24.4
(-2.3)
A 		49
(-0.6)
P 		102.4
(3)
P 		89
C 16.7
(-2.2)
A 		19.2
(-2.1)
A 		1.7
(-3)
A 		25.6
(-1.7)
A 		49.3
(-0.4)
P 		113
(3)
P 		111
avr 19.3
(-2.9) 		19.7
(-2.9) 		17.5
(-3) 		17.8
(-3) 		50.3
(-0.8) 		107.5
(3) 		90
No Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 11
1 2 3 4 range
A 5.4
(3)
A 		0.9
(-2.6)
A 		4.1
(1.4)
A 		0.6
(-3)
A 		5
B 6.2
(-0.1)
A 		2.5
(-2.4)
A 		1.5
(-3)
A 		11.3
(3)
A 		10
C 6.5
(0.5)
A 		3.9
(-1.7)
A 		2.3
(-3)
A 		9.6
(3)
A 		7
avr 6
(1.5) 		2.4
(-3) 		2.6
(-2.8) 		7.2
(3) 		5

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 38
1 2 3 4 5 6 range
A 4.3
(-2.2)
A 		9.4
(-1)
A 		3.8
(-2.3)
A 		0.8
(-3)
A 		15.9
(0.6)
A 		26
(3)
P 		25
B 6.2
(-2.7)
A 		4.5
(-3)
A 		8.1
(-2.4)
A 		6.5
(-2.6)
A 		19.9
(-0.3)
P 		38.2
(3)
P 		34
C 6.2
(-2.1)
A 		5.9
(-2.1)
A 		0.4
(-3)
A 		5.2
(-2.2)
A 		16
(-0.5)
P 		37.8
(3)
P 		37
avr 5.6
(-2.7) 		6.6
(-2.5) 		4.1
(-3) 		4.2
(-3) 		17.3
(-0.4) 		34
(3) 		30
NetAffx Links Cluster Members
Consensus/Exemplar
Group Members
GeneChip Array Information
Probe Set ID 191808_s_at
GeneChip Array C. elegans Genome Array
Organism Common Name Nematode
Probe Design Information
Transcript ID(Array Design) affy.Ce.9452
Sequence Type Exemplar sequence
Representative Public ID ZK1251.5 NCBI
Target Description ZK1251.5 /REP_DB=WormBase Gene ID /WP=CE03852 /TR=Q23433 /GB=CAA92501.1 /SUBMIT=HINXTON /CHR=4 /FEA=Sanger Annotation /DEF=protein-tyrosine phosphatase
Cluster Evidence This cluster is supported by a Sanger Annotation.
Annotation Method Description
Annotation Description This probe set was annotated using the Matching Probes based pipeline to a RefSeq identifier using 1 transcript(s).
Annotation Grade This is a grade A annotation.
Annotation Transcript Cluster (# of Matching Probes) NM_068374(11)
Transcript Assignments
Representative
Transcript		 Description Matching Probes Related Probesets by Grade
NM_068374 NCBI Caenorhabditis elegans ZK354.8 (ZK354.8) mRNA, complete cds. 11/11 A 
SNAP00000006009 ENSEMBL cdna:SNAP chromosome:CEL140:IV:5304026:5306061:-1 11/11 None
GENEFINDER00000006017 ENSEMBL cdna:GeneFinder chromosome:CEL140:IV:5304026:5307663:-1 11/11 None
SNAP00000023384 ENSEMBL cdna:SNAP chromosome:CEL140:IV:9687028:9687552:-1 11/11 None
GENEFINDER00000023396 ENSEMBL cdna:GeneFinder chromosome:CEL140:IV:9687028:9687561:-1 11/11 None
ZK354.8 ENSEMBL cdna:known chromosome:CEL140:IV:5304010:5306121:-1 gene:ZK354.8 11/11 A 
ZK1251.5 ENSEMBL cdna:pseudogene chromosome:CEL140:IV:9687028:9688187:-1 gene:ZK1251.5 11/11 A 
Annotation Notes
There are no noteworthy cross hybridizing mRNAs found for this probe set.
Genomic Alignment of Consensus/Exemplar Sequence
Assembly Wormbase March 2004
Alignment(s)
Position Identity Coverage Cytoband
chrIV:9687033-9688193(-) 100.0 100.0
chrIV:5304051-5305949(-) 93.47 93.47
Public Domain and Genome References
Gene Title protein phosphatase
Ensembl ZK354.8
ZK1251.5
Entrez Gene 191295 Entrez gene
SwissProt P91568 EMBL-EBI
WormBase CE15324 Wormbase
Functional Annotations
Gene Ontology
GO Biological Process (view graph)
ID Description Evidence Links
6470 protein amino acid dephosphorylation inferred from electronic annotation QuickGO AmiGO
GO Molecular Function (view graph)
ID Description Evidence Links
4721 phosphoprotein phosphatase activity inferred from electronic annotation QuickGO AmiGO
4725 protein tyrosine phosphatase activity inferred from electronic annotation QuickGO AmiGO
Protein Similarities
Method ID Description E-Value
blast AAB42260 Hypothetical protein ZK354.8 [Caenorhabditis elegans] ref|NP_500775.1| ZK354.8 [Caenorhabditis elegans] 0.0
blast CAE58977 Hypothetical protein CBG02250 [Caenorhabditis briggsae] 1.0E-157
blast CAE58977 Hypothetical protein CBG02250 [Caenorhabditis briggsae] 1.0E-155
blast AAB42261 Hypothetical protein ZK354.9 [Caenorhabditis elegans] ref|NP_500776.1| ZK354.9 [Caenorhabditis elegans] 1.0E-145
blast CAE60407 Hypothetical protein CBG04012 [Caenorhabditis briggsae] 1.0E-118
Protein Domains
Database ID Description E-Value
Pfam IPR000242 EMBL-EBI Tyrosine specific protein phosphatase 3.9E-98
Pfam IPR004843 EMBL-EBI Metallo-phosphoesterase 1.5E-38
Pfam IPR000242 EMBL-EBI Tyrosine specific protein phosphatase 3.9E-98
Pfam IPR000242 EMBL-EBI Tyrosine specific protein phosphatase 4.3E-40
Pfam IPR000242 EMBL-EBI Tyrosine specific protein phosphatase 8.5E-41
Sequence
Target Sequence 
>C. ELEGANS:191808_S_AT
cgcaattggcctgatcacggtgttcccgacaattttctgtcaccgttccgtttgttgact
gttgtcaagagttgcacaaaaccaatagttgtacactgctctgctggtgtcggtcgaaca
ggcacgcttgctctcattttgattatcctcgagtcaatttgtcttccggatttcattgga
gttccacgccttctggcaaaacttcgagaggagcgtttcagagcaatccaaacggaagtg
caatatttgtacgctcatcgatgcgtcctggaatatttggcactgaagaagtatgttcaa
tctcgcgaagattttgccaaattcgccaagg

BLASTn GenBank NR
Probe Info
Probe Sequence(5'-3') Probe X Probe Y Probe Interrogation
Position 		Strandedness
CGCAATTGGCCTGATCACGGTGTTC 468 253 238 Antisense
GTGTTCCCGACAATTTTCTGTCACC 570 485 257 Antisense
GTCACCGTTCCGTTTGTTGACTGTT 572 461 276 Antisense
CTTGCTCTCATTTTGATTATCCTCG 188 219 364 Antisense
ATCCTCGAGTCAATTTGTCTTCCGG 527 39 382 Antisense
GTCTTCCGGATTTCATTGGAGTTCC 519 467 398 Antisense
TTCCACGCCTTCTGGCAAAACTTCG 323 697 419 Antisense
TTTGTACGCTCATCGATGCGTCCTG 72 663 483 Antisense
GCGTCCTGGAATATTTGGCACTGAA 625 289 500 Antisense
GAAGTATGTTCAATCTCGCGAAGAT 322 337 525 Antisense
GAAGATTTTGCCAAATTCGCCAAGG 674 337 544 Antisense
Sequence Source Affymetrix Proprietary Database