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[191793_at] metalloproteinase inhibitor

Description K07C11.5 /REP_DB=WormBase Gene ID /WP=CE07348 /TR=Q21265 /GB=AAA96174.1 /SUBMIT=ST.LOUIS /CHR=5 /FEA=Sanger Annotation /DEF=metalloproteinase inhibitor
Cluster 6grp_highest_10_10 > 66      6grp_high1_10_10 > 65      4grp_highest_8_8 > 15      4grp_high_8_8 > 14      6grp_highest_nonorm > 46      6grp_total > 65      4grp_total > 10      6grp_highest_sub > Da      6grp_cgc > 46      4grp_rule_based > L4      

Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 1975
1 2 3 4 range
A 2262
(-2)
P 		2076.7
(-3)
P 		2151.9
(-2.6)
P 		3227.7
(3)
P 		1151
B 1752.5
(-3)
P 		2362.4
(-1.1)
P 		1931.7
(-2.5)
P 		3727.5
(3)
P 		1975
C 2282.8
(-3)
P 		2317.1
(-2.7)
P 		2296.2
(-2.9)
P 		3099.3
(3)
P 		817
avr 2099.1
(-3) 		2252.1
(-2.3) 		2126.6
(-2.9) 		3351.5
(3) 		1252

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 1578
1 2 3 4 5 6 range
A 3189.1
(1.8)
P 		2216.9
(-3)
P 		2952
(0.6)
P 		3174.7
(1.8)
P 		2326.5
(-2.5)
P 		3426.7
(3)
P 		1210
B 3313.5
(1.8)
P 		2435.1
(-3)
P 		3532.9
(3)
P 		2703.3
(-1.5)
P 		3063.4
(0.4)
P 		3273.5
(1.6)
P 		1098
C 3054.3
(-0.7)
P 		2734.3
(-2.3)
P 		3427.8
(1.2)
P 		3795.2
(3)
P 		2600.5
(-3)
P 		3723.5
(2.6)
P 		1195
avr 3185.6
(1.3) 		2462.1
(-3) 		3304.2
(2) 		3224.4
(1.5) 		2663.5
(-1.8) 		3474.6
(3) 		1013
No Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 376
1 2 3 4 range
A 823.6
(3)
P 		450.8
(-3)
P 		562.6
(-1.2)
P 		472.5
(-2.7)
P 		373
B 558.9
(-1.1)
P 		583.5
(-0.6)
P 		447.6
(-3)
P 		794.3
(3)
P 		347
C 755.7
(2)
P 		666.2
(0.1)
P 		800.3
(3)
P 		522.6
(-3)
P 		278
avr 712.7
(3) 		566.8
(-3) 		603.5
(-1.5) 		596.5
(-1.8) 		146

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 659
1 2 3 4 5 6 range
A 587.9
(-3)
P 		788.4
(1.9)
P 		642.9
(-1.7)
P 		805.2
(2.3)
P 		702
(-0.2)
P 		834.3
(3)
P 		246
B 1152.9
(2)
P 		810.5
(-1.9)
P 		857.9
(-1.4)
P 		716
(-3)
P 		1244.6
(3)
P 		1220.7
(2.7)
P 		529
C 1132.1
(1.6)
P 		834.3
(-2.1)
P 		872.4
(-1.6)
P 		763.2
(-3)
P 		841.5
(-2)
P 		1246.5
(3)
P 		483
avr 957.6
(0.5) 		811.1
(-2.1) 		791.1
(-2.5) 		761.5
(-3) 		929.4
(-0) 		1100.5
(3) 		339
NetAffx Links Cluster Members
Consensus/Exemplar
GeneChip Array Information
Probe Set ID 191793_at
GeneChip Array C. elegans Genome Array
Organism Common Name Nematode
Probe Design Information
Transcript ID(Array Design) affy.Ce.11883
Sequence Type Exemplar sequence
Representative Public ID K07C11.5 NCBI
Target Description K07C11.5 /REP_DB=WormBase Gene ID /WP=CE07348 /TR=Q21265 /GB=AAA96174.1 /SUBMIT=ST.LOUIS /CHR=5 /FEA=Sanger Annotation /DEF=metalloproteinase inhibitor
Cluster Evidence This cluster is supported by a Sanger Annotation.
Annotation Method Description
Annotation Description This probe set was annotated using the Matching Probes based pipeline to a RefSeq identifier using 1 transcript(s).
Annotation Grade This is a grade A annotation.
Annotation Transcript Cluster (# of Matching Probes) NM_072712(11)
Transcript Assignments
Representative
Transcript		 Description Matching Probes Related Probesets by Grade
NM_072712 NCBI Caenorhabditis elegans Temporarily Assigned Gene name family member (tag-225) (tag-225) mRNA, complete cds. 11/11 None
SNAP00000021024 ENSEMBL cdna:SNAP chromosome:CEL140:V:8204399:8205060:1 11/11 None
GENEFINDER00000021035 ENSEMBL cdna:GeneFinder chromosome:CEL140:V:8204399:8208350:1 11/11 None
K07C11.5.1 ENSEMBL cdna:known chromosome:CEL140:V:8204394:8205115:1 gene:K07C11.5 11/11 None
K07C11.5.2 ENSEMBL cdna:known chromosome:CEL140:V:8204399:8205115:1 gene:K07C11.5 11/11 None
Annotation Notes
There are no noteworthy cross hybridizing mRNAs found for this probe set.
Genomic Alignment of Consensus/Exemplar Sequence
Assembly Wormbase March 2004
Alignment(s)
Position Identity Coverage Cytoband
chrV:8204399-8205061(+) 100.0 100.0
Public Domain and Genome References
Gene Title metalloproteinase inhibitor
Gene Symbol tag-225
Ensembl K07C11.5
Entrez Gene 179197 Entrez gene
SwissProt Q21265 EMBL-EBI
WormBase CE07348 Wormbase
Functional Annotations
Gene Ontology
GO Cellular Component (view graph)
ID Description Evidence Links
5578 extracellular matrix (sensu Metazoa) inferred from electronic annotation QuickGO AmiGO
GO Molecular Function (view graph)
ID Description Evidence Links
8191 metalloendopeptidase inhibitor activity inferred from electronic annotation QuickGO AmiGO
Protein Similarities
Method ID Description E-Value
blast AAA96175 Hypothetical protein K07C11.4 [Caenorhabditis elegans] ref|NP_505114.1| K07C11.4 [Caenorhabditis elegans] 0.0
blast AAA96174 Temporarily assigned gene name protein 225 [Caenorhabditis elegans] ref|NP_505113.1| Temporarily Assigned Gene name family member (tag-225) [Caenorhabditis elegans] gb|AAG50211.1| tissue inhibitor of metalloproteinase 2 [Caenorhabditis elegans] sp|Q21265|TIMPL_CAEEL Putative metalloproteinase inhibitor K07C11.5 precursor (TIMP-like protein) 1.0E-77
blast CAE66106 Hypothetical protein CBG11326 [Caenorhabditis briggsae] 4.0E-74
blast Q04456 Gut esterase 1 precursor (Non-specific carboxylesterase) emb|CAE62343.1| Hypothetical protein CBG06418 [Caenorhabditis briggsae] gb|AAA28056.1| esterase 9.0E-71
Protein Domains
Database ID Description E-Value
Pfam IPR001820 EMBL-EBI Tissue inhibitor of metalloproteinase 4.0E-5
Pfam IPR002018 EMBL-EBI Carboxylesterase, type B 1.0E-126
Trans Membrane
ID Number Of Domains Domain Boundaries
GENEFINDER00000021035 2 182-204,216-238
Sequence
Target Sequence 
>C. ELEGANS:191793_AT
tttatctttatctctagtcattctatcagttctcattgctgtaactcttgcttgcaagtg
tagagagcaatcaaccaaggaatcattctgcaatgctcactgggtttctcatgtcaaagt
gaaggtccgtgtaggaaaacaaggacttccagaaggatccgagagaaagggattgaataa
tttgagatacactgtgcaacatgtcgaggtttttaagaaaccatccaacatgacaactct
gccagatgaaattttcactccatcagaagctccagcttgcgggctcaagattgccgccgg
tcatgaatatctacttgctggtcgtgttgaaggaccaaatgctttgtatactgttctttg
cggtcaagtactgcca

BLASTn GenBank NR
Probe Info
Probe Sequence(5'-3') Probe X Probe Y Probe Interrogation
Position 		Strandedness
TTTATCTTTATCTCTAGTCATTCTA 208 675 21 Antisense
AGTCATTCTATCAGTTCTCATTGCT 570 61 36 Antisense
TCTCATTGCTGTAACTCTTGCTTGC 361 613 51 Antisense
ATTCTGCAATGCTCACTGGGTTTCT 624 5 105 Antisense
GATACACTGTGCAACATGTCGAGGT 652 423 206 Antisense
CATCCAACATGACAACTCTGCCAGA 710 209 242 Antisense
AATTTTCACTCCATCAGAAGCTCCA 360 175 270 Antisense
GCTTGCGGGCTCAAGATTGCCGCCG 251 307 295 Antisense
AGATTGCCGCCGGTCATGAATATCT 324 65 308 Antisense
GAATATCTACTTGCTGGTCGTGTTG 160 327 325 Antisense
TGTTCTTTGCGGTCAAGTACTGCCA 119 561 372 Antisense
Sequence Source Affymetrix Proprietary Database