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[191766_s_at] protein-tyrosine phosphatase

Description F47B3.1 /REP_DB=WormBase Gene ID /WP=CE10616 /TR=O01557 /GB=AAB52356.1 /SUBMIT=ST.LOUIS /CHR=1 /FEA=Sanger Annotation /DEF=protein-tyrosine phosphatase
Cluster 6grp_total > 77      4grp_total > 35      6grp_total_sub > Increase      6grp_rule_based > S6      

Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 52
1 2 3 4 range
A 9.3
(-2.4)
A 		9.1
(-2.4)
A 		5.3
(-3)
A 		44.3
(3)
A 		39
B 9.9
(-2.8)
A 		57.6
(3)
A 		11
(-2.7)
A 		8.6
(-3)
A 		49
C 11.1
(-2)
A 		24.7
(2.4)
A 		7.9
(-3)
A 		26.4
(3)
A 		19
avr 10.1
(-2.5) 		30.5
(3) 		8.1
(-3) 		26.4
(1.9) 		22

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 113
1 2 3 4 5 6 range
A 29.5
(-1)
A 		7.7
(-2.9)
A 		9.3
(-2.7)
A 		6.3
(-3)
A 		12.6
(-2.5)
A 		77.5
(3)
P 		71
B 7.7
(-2.8)
A 		4.6
(-3)
A 		10.1
(-2.6)
A 		4.5
(-3)
A 		30.4
(-1.1)
A 		85.3
(3)
A 		81
C 8.6
(-3)
A 		9.9
(-2.9)
A 		37.4
(-1.4)
A 		8.6
(-3)
A 		32.9
(-1.7)
A 		117.5
(3)
A 		109
avr 15.3
(-2.4) 		7.4
(-2.9) 		18.9
(-2.1) 		6.5
(-3) 		25.3
(-1.7) 		93.4
(3) 		87
No Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 13
1 2 3 4 range
A 3.4
(-0.6)
A 		2
(-2.3)
A 		1.4
(-3)
A 		6.5
(3)
A 		5
B 3.2
(-2.3)
A 		14.2
(3)
A 		2.5
(-2.7)
A 		1.8
(-3)
A 		12
C 3.7
(-1.6)
A 		7.1
(3)
A 		2.7
(-3)
A 		4.5
(-0.5)
A 		4
avr 3.4
(-1.7) 		7.8
(3) 		2.2
(-3) 		4.3
(-0.8) 		6

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 38
1 2 3 4 5 6 range
A 5.4
(-1.7)
A 		2.7
(-2.6)
A 		2
(-2.9)
A 		1.6
(-3)
A 		3.8
(-2.2)
A 		18.9
(3)
P 		17
B 2.7
(-2.7)
A 		1.5
(-2.9)
A 		2.5
(-2.7)
A 		1.2
(-3)
A 		12.4
(-0.8)
A 		31.8
(3)
A 		31
C 3.2
(-2.8)
A 		3
(-2.8)
A 		9.5
(-1.8)
A 		1.7
(-3)
A 		10.6
(-1.6)
A 		39.3
(3)
A 		38
avr 3.8
(-2.5) 		2.4
(-2.8) 		4.7
(-2.3) 		1.5
(-3) 		8.9
(-1.4) 		30
(3) 		29
NetAffx Links Cluster Members
Consensus/Exemplar
Group Members
GeneChip Array Information
Probe Set ID 191766_s_at
GeneChip Array C. elegans Genome Array
Organism Common Name Nematode
Probe Design Information
Transcript ID(Array Design) affy.Ce.80
Sequence Type Exemplar sequence
Representative Public ID F47B3.1 NCBI
Target Description F47B3.1 /REP_DB=WormBase Gene ID /WP=CE10616 /TR=O01557 /GB=AAB52356.1 /SUBMIT=ST.LOUIS /CHR=1 /FEA=Sanger Annotation /DEF=protein-tyrosine phosphatase
Cluster Evidence This cluster is supported by a Sanger Annotation.
Annotation Method Description
Annotation Description This probe set was annotated using the Matching Probes based pipeline to a RefSeq identifier using 1 transcript(s).
Annotation Grade This is a grade A annotation.
Annotation Transcript Cluster (# of Matching Probes) NM_058874(11), NM_058877(11)
Transcript Assignments
Representative
Transcript		 Description Matching Probes Related Probesets by Grade
NM_058874 NCBI Caenorhabditis elegans F47B3.6 (F47B3.6) mRNA, complete cds. 11/11 None
NM_058877 NCBI Caenorhabditis elegans F47B3.1 (F47B3.1) mRNA, complete cds. 11/11 None
GENEFINDER00000030473 ENSEMBL cdna:GeneFinder chromosome:CEL140:I:3963117:3969943:-1 11/11 None
F47B3.6 ENSEMBL cdna:known chromosome:CEL140:I:3965740:3967077:-1 gene:F47B3.6 11/11 None
F47B3.1 ENSEMBL cdna:known chromosome:CEL140:I:3972164:3973705:1 gene:F47B3.1 11/11 None
Annotation Notes
Cross Hybridizing mRNA Matched Probes Nature of Assignment Related Probesets by Grade
SNAP00000030467 8/11 Cross Hyb Matching Probes None
SNAP00000015483 7/11 Cross Hyb Matching Probes None
GENEFINDER00000015494 8/11 Cross Hyb Matching Probes None
Genomic Alignment of Consensus/Exemplar Sequence
Assembly Wormbase March 2004
Alignment(s)
Position Identity Coverage Cytoband
chrI:3972163-3973705(+) 100.0 100.0
chrI:3965739-3967281(-) 100.0 100.0
Public Domain and Genome References
Gene Title protein-tyrosine phosphatase

Ensembl F47B3.6
F47B3.1
Entrez Gene 171982 Entrez gene
171984 Entrez gene
SwissProt O01557 EMBL-EBI
O01555 EMBL-EBI
WormBase CE10616 Wormbase
CE36648 Wormbase
Functional Annotations
Gene Ontology
GO Biological Process (view graph)
ID Description Evidence Links
6470 protein amino acid dephosphorylation inferred from electronic annotation QuickGO AmiGO
GO Molecular Function (view graph)
ID Description Evidence Links
4721 phosphoprotein phosphatase activity inferred from electronic annotation QuickGO AmiGO
4725 protein tyrosine phosphatase activity inferred from electronic annotation QuickGO AmiGO
Protein Similarities
Method ID Description E-Value
blast AAB52356 Hypothetical protein F47B3.1 [Caenorhabditis elegans] ref|NP_491278.1| F47B3.1 [Caenorhabditis elegans] 0.0
blast AAB52362 Hypothetical protein F47B3.7 [Caenorhabditis elegans] ref|NP_491276.1| F47B3.7 [Caenorhabditis elegans] 0.0
blast AAB52356 Hypothetical protein F47B3.1 [Caenorhabditis elegans] ref|NP_491278.1| F47B3.1 [Caenorhabditis elegans] 1.0E-176
blast AAB52361 Hypothetical protein F47B3.6 [Caenorhabditis elegans] ref|NP_491275.2| F47B3.6 [Caenorhabditis elegans] 1.0E-176
blast AAB52361 Hypothetical protein F47B3.6 [Caenorhabditis elegans] ref|NP_491275.2| F47B3.6 [Caenorhabditis elegans] 1.0E-175
Protein Domains
Database ID Description E-Value
Pfam IPR000242 EMBL-EBI Tyrosine specific protein phosphatase 1.3E-102
Pfam IPR000242 EMBL-EBI Tyrosine specific protein phosphatase 6.2E-92
Pfam IPR004296 EMBL-EBI Protein of unknown function DUF236 3.6E-14
Pfam IPR000242 EMBL-EBI Tyrosine specific protein phosphatase 6.2E-92
Pfam IPR000242 EMBL-EBI Tyrosine specific protein phosphatase 6.2E-92
Sequence
Target Sequence 
>C. ELEGANS:191766_S_AT
agtggagtgcgtgatcatgctgtgcaattgcatcgaaacgggcaaaataaaatgccatca
gtattggccattggagcagggccagaaattagttttcggcgaggcaccgaacaccatttc
ggttgccaacttgggtgctaagaaaatggcgccggacgagcaatgcatcaatgtaacgac
tttgaaagttgactggggacaaggctcccgaactatccagcatcttcaatgggagaattg
gccggatcgtggagtgccgcagaccaacttgacagcaataaacctcctttcggcaacccg
tggcaaccagaatcccattctggtccactgctcagctggaattgggcgcaccggaaccat
cgtcgcgattgcttacgttcaagataagatgatggcaggggaaaactgcatggcgatgaa
cgaattgatcaaggaactccgctctcaccgtccgtggtctatccagaacgaattccaata
cttgtacctccatcgtgtgctgctctcgtatttcttggagcgc

BLASTn GenBank NR
Probe Info
Probe Sequence(5'-3') Probe X Probe Y Probe Interrogation
Position 		Strandedness
AGTGGAGTGCGTGATCATGCTGTGC 282 59 486 Antisense
GAACACCATTTCGGTTGCCAACTTG 667 351 594 Antisense
AAAATGGCGCCGGACGAGCAATGCA 151 133 628 Antisense
TGACTGGGGACAAGGCTCCCGAACT 297 571 675 Antisense
TTGACAGCAATAAACCTCCTTTCGG 616 701 754 Antisense
TCAGCTGGAATTGGGCGCACCGGAA 532 623 817 Antisense
GAACCATCGTCGCGATTGCTTACGT 584 345 839 Antisense
ATTGATCAAGGAACTCCGCTCTCAC 391 5 909 Antisense
CGTCCGTGGTCTATCCAGAACGAAT 77 245 934 Antisense
GAATTCCAATACTTGTACCTCCATC 564 323 955 Antisense
GCTGCTCTCGTATTTCTTGGAGCGC 277 297 984 Antisense
Sequence Source Affymetrix Proprietary Database