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[191759_at] flavin-containing monoxygenase

Description K08C7.5 /REP_DB=WormBase Gene ID /WP=CE06138 /TR=Q21310 /GB=CAA94290.1 /SUBMIT=HINXTON /CHR=4 /FEA=Sanger Annotation /DEF=dimethylaniline monooxygenase
Cluster 6grp_highest_10_10 > 27      6grp_high1_10_10 > 62      4grp_highest_8_8 > 50      4grp_high_8_8 > 40      6grp_highest_nonorm > 18      6grp_total > 62      4grp_total > 46      6grp_highest_sub > 03_04      6grp_cgc > 75      6grp_high1_sub > 03      6grp_cgc_sub > 03_04      6grp_total_sub > Hat      6grp_rule_based > S3      4grp_rule_based > L1      

Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 2994
1 2 3 4 range
A 3244.2
(3)
P 		829.9
(-1.8)
P 		732.1
(-2)
P 		250.1
(-3)
P 		2994
B 3197.7
(3)
P 		953.2
(-1.6)
P 		562.3
(-2.4)
P 		263.4
(-3)
P 		2934
C 3110.7
(3)
P 		958.9
(-1.6)
P 		614.6
(-2.3)
P 		288.4
(-3)
P 		2822
avr 3184.2
(3) 		914
(-1.7) 		636.3
(-2.2) 		267.3
(-3) 		2917

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 9424
1 2 3 4 5 6 range
A 10964
(-3)
P 		14845.1
(-0.3)
P 		19538
(3)
P 		18481.7
(2.3)
P 		14818.2
(-0.3)
P 		13850.9
(-1)
P 		8574
B 11119.8
(-3)
P 		14669.4
(0.3)
P 		17509.4
(3)
P 		17074.1
(2.6)
P 		14144.2
(-0.2)
P 		12212.1
(-2)
P 		6390
C 10414.8
(-3)
P 		14880.9
(-0.2)
P 		19838.7
(3)
P 		18798.6
(2.3)
P 		14346.2
(-0.5)
P 		12428.2
(-1.7)
P 		9424
avr 10832.9
(-3) 		14798.5
(-0.1) 		18962
(3) 		18118.1
(2.4) 		14436.2
(-0.3) 		12830.4
(-1.5) 		8129
No Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 1145
1 2 3 4 range
A 1181.2
(3)
P 		180.1
(-2.2)
P 		191.4
(-2.2)
P 		36.6
(-3)
P 		1145
B 1019.7
(3)
P 		235.4
(-1.9)
P 		130.3
(-2.5)
P 		56.1
(-3)
P 		964
C 1029.7
(3)
P 		275.7
(-1.6)
P 		214.2
(-2)
P 		48.6
(-3)
P 		981
avr 1076.9
(3) 		230.4
(-1.9) 		178.6
(-2.2) 		47.1
(-3) 		1030

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 3726
1 2 3 4 5 6 range
A 2021.1
(-3)
P 		5279.7
(3)
P 		4255
(1.1)
P 		4687.4
(1.9)
P 		4471.5
(1.5)
P 		3372.3
(-0.5)
P 		3259
B 3869.1
(-3)
P 		4882.8
(0.2)
P 		4251.8
(-1.8)
P 		4522.4
(-0.9)
P 		5746.6
(3)
P 		4553.8
(-0.8)
P 		1878
C 3860.3
(-2.6)
P 		4540.6
(0.6)
P 		5049.3
(3)
P 		3780.4
(-3)
P 		4642.2
(1.1)
P 		4160.4
(-1.2)
P 		1269
avr 3250.2
(-3) 		4901
(2.8) 		4518.7
(1.5) 		4330.1
(0.8) 		4953.4
(3) 		4028.8
(-0.3) 		1703
NetAffx Links Cluster Members
Consensus/Exemplar
GeneChip Array Information
Probe Set ID 191759_at
GeneChip Array C. elegans Genome Array
Organism Common Name Nematode
Probe Design Information
Transcript ID(Array Design) affy.Ce.8972
Sequence Type Exemplar sequence
Representative Public ID K08C7.5 NCBI
Target Description K08C7.5 /REP_DB=WormBase Gene ID /WP=CE06138 /TR=Q21310 /GB=CAA94290.1 /SUBMIT=HINXTON /CHR=4 /FEA=Sanger Annotation /DEF=dimethylaniline monooxygenase
Cluster Evidence This cluster is supported by a Sanger Annotation.
Annotation Method Description
Annotation Description This probe set was annotated using the Matching Probes based pipeline to a RefSeq identifier using 1 transcript(s).
Annotation Grade This is a grade A annotation.
Annotation Transcript Cluster (# of Matching Probes) NM_069571(11)
Transcript Assignments
Representative
Transcript		 Description Matching Probes Related Probesets by Grade
NM_069571 NCBI Caenorhabditis elegans Flavin-containing MonoOxygenase family member (fmo-2) (fmo-2) mRNA, complete cds. 11/11 None
SNAP00000016925 ENSEMBL cdna:SNAP chromosome:CEL140:IV:10682524:10684298:1 11/11 None
GENEFINDER00000016929 ENSEMBL cdna:GeneFinder chromosome:CEL140:IV:10682524:10684294:1 11/11 None
K08C7.5 ENSEMBL cdna:known chromosome:CEL140:IV:10682496:10684357:1 gene:K08C7.5 11/11 None
Annotation Notes
There are no noteworthy cross hybridizing mRNAs found for this probe set.
Genomic Alignment of Consensus/Exemplar Sequence
Assembly Wormbase March 2004
Alignment(s)
Position Identity Coverage Cytoband
chrIV:10682529-10684304(+) 100.0 100.0
Public Domain and Genome References
Gene Title flavin-containing monoxygenase
Gene Symbol fmo-2
Ensembl K08C7.5
Entrez Gene 177958 Entrez gene
SwissProt Q21310 EMBL-EBI
WormBase CE06138 Wormbase
Functional Annotations
Gene Ontology
GO Biological Process (view graph)
ID Description Evidence Links
6118 electron transport inferred from electronic annotation QuickGO AmiGO
GO Cellular Component (view graph)
ID Description Evidence Links
5792 microsome inferred from electronic annotation QuickGO AmiGO
GO Molecular Function (view graph)
ID Description Evidence Links
4497 monooxygenase activity inferred from electronic annotation QuickGO AmiGO
4499 dimethylaniline monooxygenase (N-oxide-forming) activity inferred from electronic annotation QuickGO AmiGO
15036 disulfide oxidoreductase activity inferred from electronic annotation QuickGO AmiGO
Protein Similarities
Method ID Description E-Value
blast CAA94290 Hypothetical protein K08C7.5 [Caenorhabditis elegans] ref|NP_501972.1| Flavin-containing MonoOxygenase family member (fmo-2) [Caenorhabditis elegans] emb|CAE46541.1| flavin monooxygenase [Caenorhabditis elegans] 0.0
blast CAE60758 Hypothetical protein CBG04445 [Caenorhabditis briggsae] 0.0
blast CAA94291 Hypothetical protein K08C7.2 [Caenorhabditis elegans] ref|NP_501968.2| Flavin-containing MonoOxygenase family member (fmo-1) [Caenorhabditis elegans] emb|CAE46540.1| flavin monooxygenase [Caenorhabditis elegans] 1.0E-179
Protein Domains
Database ID Description E-Value
Pfam IPR000960 EMBL-EBI Flavin-containing monooxygenase FMO 1.0E-126
Pfam IPR000960 EMBL-EBI Flavin-containing monooxygenase FMO 1.0E-126
Trans Membrane
ID Number Of Domains Domain Boundaries
NP_501972.1 1 509-528
K08C7.5 1 509-528
SNAP00000016925 2 7-29,524-543
GENEFINDER00000016929 1 508-527
Sequence
Target Sequence 
>C. ELEGANS:191759_AT
aatacatgttcccagtggctacttccgatcataattccttgtgcatcattggtctcattc
aaccatttggatcaattatgccagtttccgaacaacaagctcgtgtattctttgccaaca
tggtttctggaaacaatttaattcctaaaaagtcacagatgtctgaggatgttttgaata
aaaaagaagcaatggctcagcagttcgtaaaatccagacgtcacactattcaagtcgatt
atattccatatatggatgaactcgcagagcttattggatgtcaagtcccacttcttcgaa
cactatttactgatccagttcttggtcttcgcctcttctttggtccaaacgcagggtatt
gctacagattggctgggccacacacttggaacggtgccagaaatgcgattttgactattg
atcaacgtgtccgaatggcaactacaaccaaaccggagcctaccaattacactgttccac
tagtgatctcttctatta

BLASTn GenBank NR
Probe Info
Probe Sequence(5'-3') Probe X Probe Y Probe Interrogation
Position 		Strandedness
AATACATGTTCCCAGTGGCTACTTC 460 171 1073 Antisense
GGCTACTTCCGATCATAATTCCTTG 375 537 1089 Antisense
ATTCCTTGTGCATCATTGGTCTCAT 120 9 1106 Antisense
GATCAATTATGCCAGTTTCCGAACA 83 423 1142 Antisense
ACAAGCTCGTGTATTCTTTGCCAAC 707 113 1167 Antisense
TCCCACTTCTTCGAACACTATTTAC 622 597 1358 Antisense
TACTGATCCAGTTCTTGGTCTTCGC 64 647 1380 Antisense
GCCTCTTCTTTGGTCCAAACGCAGG 57 283 1403 Antisense
GCCACACACTTGGAACGGTGCCAGA 370 279 1449 Antisense
GGAGCCTACCAATTACACTGTTCCA 672 521 1527 Antisense
GTTCCACTAGTGATCTCTTCTATTA 292 441 1546 Antisense
Sequence Source Affymetrix Proprietary Database