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[191742_s_at] protein-tyrosine phosphatase

Description H06O01.4 /REP_DB=WormBase Gene ID /WP=CE11576 /TR=O17906 /GB=CAB07479.1 /SUBMIT=HINXTON /CHR=1 /FEA=Sanger Annotation /DEF=protein-tyrosine phosphatase
Cluster 6grp_total > 78      4grp_total > 03      6grp_total_sub > Increase      6grp_rule_based > S6      

Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 85
1 2 3 4 range
A 8.2
(-3)
A 		9.4
(-2.2)
A 		16.6
(2.5)
A 		17.3
(3)
A 		9
B 37.4
(0.2)
A 		10.7
(-3)
A 		13.3
(-2.7)
A 		61.5
(3)
A 		51
C 7.7
(-3)
A 		21.5
(-2)
A 		8.5
(-2.9)
A 		93
(3)
A 		85
avr 17.8
(-2.3) 		13.9
(-2.9) 		12.8
(-3) 		57.3
(3) 		45

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 115
1 2 3 4 5 6 range
A 29.6
(-1.2)
A 		9.9
(-2.8)
A 		41
(-0.3)
A 		7
(-3)
A 		62.7
(1.4)
A 		83.8
(3)
A 		77
B 9.3
(-3)
A 		10.8
(-2.9)
A 		11.4
(-2.9)
A 		20.6
(-2.4)
A 		64.4
(0)
A 		119.1
(3)
P 		110
C 4.1
(-3)
A 		16.2
(-2.3)
A 		8.5
(-2.8)
A 		16.1
(-2.3)
A 		25.6
(-1.8)
A 		113
(3)
P 		109
avr 14.3
(-2.9) 		12.3
(-3) 		20.3
(-2.5) 		14.6
(-2.9) 		50.9
(-0.5) 		105.3
(3) 		93
No Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 14
1 2 3 4 range
A 3
(-0.4)
A 		2
(-3)
A 		4.3
(3)
A 		2.5
(-1.7)
A 		2
B 11.9
(2.3)
A 		2.6
(-3)
A 		3.1
(-2.7)
A 		13.1
(3)
A 		11
C 2.6
(-3)
A 		6.2
(-1.4)
A 		2.9
(-2.9)
A 		15.7
(3)
A 		13
avr 5.8
(-0.9) 		3.6
(-2.8) 		3.4
(-3) 		10.4
(3) 		7

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 43
1 2 3 4 5 6 range
A 5.5
(-1.8)
A 		3.5
(-2.5)
A 		8.9
(-0.7)
A 		1.8
(-3)
A 		18.9
(2.5)
A 		20.4
(3)
A 		19
B 3.2
(-2.9)
A 		3.6
(-2.9)
A 		2.8
(-3)
A 		5.5
(-2.6)
A 		26.2
(0.4)
A 		44.4
(3)
P 		42
C 1.5
(-3)
A 		4.9
(-2.4)
A 		2.2
(-2.9)
A 		3.2
(-2.7)
A 		8.3
(-1.9)
A 		37.8
(3)
P 		36
avr 3.4
(-3) 		4
(-2.9) 		4.6
(-2.8) 		3.5
(-3) 		17.8
(-0.2) 		34.2
(3) 		31
NetAffx Links Cluster Members
Consensus/Exemplar
Group Members
GeneChip Array Information
Probe Set ID 191742_s_at
GeneChip Array C. elegans Genome Array
Organism Common Name Nematode
Probe Design Information
Transcript ID(Array Design) affy.Ce.1478
Sequence Type Exemplar sequence
Representative Public ID H06O01.4 NCBI
Target Description H06O01.4 /REP_DB=WormBase Gene ID /WP=CE11576 /TR=O17906 /GB=CAB07479.1 /SUBMIT=HINXTON /CHR=1 /FEA=Sanger Annotation /DEF=protein-tyrosine phosphatase
Cluster Evidence This cluster is supported by a Sanger Annotation.
Annotation Method Description
Annotation Description This probe set was annotated using the Matching Probes based pipeline to a RefSeq identifier using 1 transcript(s).
Annotation Grade This is a grade A annotation.
Annotation Transcript Cluster (# of Matching Probes) NM_059591(11), NM_059629(11)
Transcript Assignments
Representative
Transcript		 Description Matching Probes Related Probesets by Grade
NM_059591 NCBI Caenorhabditis elegans H06O01.4 (H06O01.4) mRNA, complete cds. 11/11 A 
NM_059629 NCBI Caenorhabditis elegans M05B5.1 (M05B5.1) mRNA, complete cds. 11/11 None
SNAP00000021142 ENSEMBL cdna:SNAP chromosome:CEL140:I:7011068:7011502:-1 11/11 None
GENEFINDER00000021147 ENSEMBL cdna:GeneFinder chromosome:CEL140:I:7011103:7012177:-1 10/11 None
SNAP00000017375 ENSEMBL cdna:SNAP chromosome:CEL140:I:7186084:7187561:-1 11/11 None
GENEFINDER00000017398 ENSEMBL cdna:GeneFinder chromosome:CEL140:I:7186084:7187561:-1 11/11 None
H06O01.4 ENSEMBL cdna:known chromosome:CEL140:I:7011068:7012177:-1 gene:H06O01.4 11/11 A 
M05B5.1 ENSEMBL cdna:known chromosome:CEL140:I:7186084:7187561:-1 gene:M05B5.1 11/11 None
Annotation Notes
There are no noteworthy cross hybridizing mRNAs found for this probe set.
Genomic Alignment of Consensus/Exemplar Sequence
Assembly Wormbase March 2004
Alignment(s)
Position Identity Coverage Cytoband
chrI:7010998-7012108(-) 91.92 100.0
Public Domain and Genome References
Gene Title protein-tyrosine phosphatase
protein-tyrosine phosphatase
Ensembl H06O01.4
M05B5.1
Entrez Gene 186701 Entrez gene
187450 Entrez gene
SwissProt O17906 EMBL-EBI
Q21514 EMBL-EBI
WormBase CE11576 Wormbase
CE06187 Wormbase
Functional Annotations
Gene Ontology
GO Biological Process (view graph)
ID Description Evidence Links
6470 protein amino acid dephosphorylation inferred from electronic annotation QuickGO AmiGO
GO Molecular Function (view graph)
ID Description Evidence Links
4725 protein tyrosine phosphatase activity inferred from electronic annotation QuickGO AmiGO
Protein Similarities
Method ID Description E-Value
blast CAA95832 Hypothetical protein M05B5.1 [Caenorhabditis elegans] ref|NP_492030.1| M05B5.1 [Caenorhabditis elegans] 0.0
blast CAA94276 Hypothetical protein K07F5.6 [Caenorhabditis elegans] ref|NP_501764.2| K07F5.6 [Caenorhabditis elegans] 1.0E-142
blast CAB07479 Hypothetical protein H06O01.4 [Caenorhabditis elegans] ref|NP_491992.1| H06O01.4 [Caenorhabditis elegans] 1.0E-132
Protein Domains
Database ID Description E-Value
Pfam IPR000242 EMBL-EBI Tyrosine specific protein phosphatase 8.0E-21
Pfam IPR000242 EMBL-EBI Tyrosine specific protein phosphatase 8.3E-18
Pfam IPR000242 EMBL-EBI Tyrosine specific protein phosphatase 2.8E-21
Pfam IPR000242 EMBL-EBI Tyrosine specific protein phosphatase 5.2E-23
Pfam IPR000242 EMBL-EBI Tyrosine specific protein phosphatase 3.1E-21
Trans Membrane
ID Number Of Domains Domain Boundaries
NP_491992.1 1 202-224
NP_492030.1 1 391-413
H06O01.4 1 202-224
M05B5.1 1 391-413
SNAP00000021142 1 104-122
SNAP00000017375 1 391-413
GENEFINDER00000017398 1 391-413
Sequence
Target Sequence 
>C. ELEGANS:191742_S_AT
tacaattgcaccacgtggccatggaagagctaccctgatgatgtgaagaaagtgctcgcg
ttggttcgagctcctgtcaaggaaagctcaccaacagttggaaagcagcccccagtgatt
gtaatgtgtgaccttggtctagatcgctcagctactgtagtgctcacttcaatcatcata
gaacaagtgttagatgggaaaactcccgattgtgatgacttgttcagaaagatgcgtgat
caacgtgctggagtcttcacaatgagcatcttcttcacgtatgccatccgtgc

BLASTn GenBank NR
Probe Info
Probe Sequence(5'-3') Probe X Probe Y Probe Interrogation
Position 		Strandedness
TACAATTGCACCACGTGGCCATGGA 15 643 370 Antisense
GGCCATGGAAGAGCTACCCTGATGA 18 545 386 Antisense
AAGTGCTCGCGTTGGTTCGAGCTCC 412 157 419 Antisense
CAACAGTTGGAAAGCAGCCCCCAGT 628 183 461 Antisense
GCAGCCCCCAGTGATTGTAATGTGT 117 315 474 Antisense
TGTGACCTTGGTCTAGATCGCTCAG 169 557 496 Antisense
GATCGCTCAGCTACTGTAGTGCTCA 517 417 511 Antisense
GAAAACTCCCGATTGTGATGACTTG 115 355 567 Antisense
CGTGATCAACGTGCTGGAGTCTTCA 374 245 604 Antisense
GAGTCTTCACAATGAGCATCTTCTT 633 399 620 Antisense
TCTTCTTCACGTATGCCATCCGTGC 210 617 638 Antisense
Sequence Source Affymetrix Proprietary Database