[Home] | [Total List]

[191720_at]

Description K08A8.1 /REP_DB=WormBase Gene ID /WP=CE04724 /GEN=mek-1 /TR=Q21307 /GB=AAA79746.1 /SUBMIT=ST.LOUIS /CHR=X /FEA=Sanger Annotation /DEF=Map kinase kinase
Cluster 6grp_high1_10_10 > 0      4grp_high_8_8 > 38      6grp_total > 09      4grp_total > 35      6grp_cgc > 10      

Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 179
1 2 3 4 range
A 257.9
(3)
A 		149.4
(-3)
P 		181.8
(-1.2)
P 		168.8
(-1.9)
P 		109
B 102.6
(-3)
P 		219.3
(3)
P 		116.7
(-2.3)
P 		187.2
(1.3)
A 		117
C 78.7
(-3)
P 		194.1
(3)
P 		153.1
(0.9)
P 		172.5
(1.9)
P 		115
avr 146.4
(-3) 		187.6
(3) 		150.5
(-2.4) 		176.2
(1.3) 		41

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 149
1 2 3 4 5 6 range
A 156.3
(2.3)
A 		150
(1.8)
P 		165.4
(3)
A 		147.5
(1.6)
P 		89.9
(-2.9)
P 		88.7
(-3)
P 		77
B 226.9
(3)
P 		98.2
(-3)
P 		128
(-1.6)
P 		118
(-2.1)
A 		119
(-2)
P 		130.8
(-1.5)
P 		129
C 77.8
(-3)
P 		99.8
(-0.5)
P 		93.4
(-1.2)
P 		131
(3)
A 		110.3
(0.7)
P 		86.7
(-2)
P 		53
avr 153.7
(3) 		116
(-1.4) 		128.9
(0.1) 		132.2
(0.5) 		106.4
(-2.5) 		102.1
(-3) 		52
No Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 69
1 2 3 4 range
A 93.9
(3)
A 		32.4
(-2.3)
P 		47.5
(-1)
P 		24.7
(-3)
P 		69
B 32.7
(-1.7)
P 		54.2
(3)
P 		27
(-3)
P 		39.9
(-0.2)
A 		27
C 26
(-3)
P 		55.8
(3)
P 		53.4
(2.5)
P 		29.1
(-2.4)
P 		30
avr 50.9
(3) 		47.5
(2) 		42.6
(0.5) 		31.2
(-3) 		20

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 57
1 2 3 4 5 6 range
A 28.8
(-1.6)
A 		53.3
(3)
P 		36
(-0.3)
A 		37.4
(-0)
P 		27.1
(-2)
P 		21.6
(-3)
P 		32
B 79
(3)
P 		32.7
(-2.8)
P 		31.1
(-3)
P 		31.2
(-3)
A 		48.3
(-0.8)
P 		48.8
(-0.8)
P 		48
C 28.9
(-0.4)
P 		30.4
(0.3)
P 		23.8
(-3)
P 		26.3
(-1.7)
A 		35.7
(3)
P 		29
(-0.4)
P 		12
avr 45.6
(3) 		38.8
(0.3) 		30.3
(-3) 		31.6
(-2.5) 		37
(-0.4) 		33.1
(-1.9) 		15
NetAffx Links Cluster Members
Consensus/Exemplar
GeneChip Array Information
Probe Set ID 191720_at
GeneChip Array C. elegans Genome Array
Organism Common Name Nematode
Probe Design Information
Transcript ID(Array Design) affy.Ce.16635
Sequence Type Exemplar sequence
Representative Public ID K08A8.1 NCBI
Target Description K08A8.1 /REP_DB=WormBase Gene ID /WP=CE04724 /GEN=mek-1 /TR=Q21307 /GB=AAA79746.1 /SUBMIT=ST.LOUIS /CHR=X /FEA=Sanger Annotation /DEF=Map kinase kinase
Cluster Evidence This cluster is supported by a Sanger Annotation.
Annotation Method Description
Annotation Description This probe set was annotated using the Genome Consensus/Exemplar Overlap based pipeline to a RefSeq identifier using 1 transcript(s).
Annotation Grade This is a grade C annotation.
Annotation Transcript Cluster (# of Matching Probes) NM_001029600, NM_001029601
Transcript Assignments
Representative
Transcript		 Description Matching Probes Related Probesets by Grade
NM_001029601 NCBI Caenorhabditis elegans MAP kinase kinase or Erk Kinase family member (mek-1) (mek-1) mRNA, complete cds. None
K08A8.1b ENSEMBL cdna:known chromosome:CEL140:X:7479193:7480869:1 gene:K08A8.1 None
K08A8.1a ENSEMBL cdna:known chromosome:CEL140:X:7479201:7480945:1 gene:K08A8.1 A 
NM_001029600 NCBI Caenorhabditis elegans MAP kinase kinase or Erk Kinase family member (mek-1) (mek-1) mRNA, complete cds. None
SNAP00000011624 ENSEMBL cdna:SNAP chromosome:CEL140:X:7479225:7480524:1 None
Annotation Notes
There are no noteworthy cross hybridizing mRNAs found for this probe set.
Genomic Alignment of Consensus/Exemplar Sequence
Assembly Wormbase March 2004
Alignment(s)
Position Identity Coverage Cytoband
chrX:7479199-7482195(+) 100.0 100.0
Public Domain and Genome References
Ensembl K08A8.1
Functional Annotations
Protein Similarities
Method ID Description E-Value
blast AAA79746 Map kinase kinase or erk kinase protein 1, isoform a [Caenorhabditis elegans] ref|NP_001024771.1| MAP kinase kinase or Erk Kinase family member (mek-1) [Caenorhabditis elegans] 0.0
blast AAP46283 Map kinase kinase or erk kinase protein 1, isoform b [Caenorhabditis elegans] ref|NP_001024772.1| MAP kinase kinase or Erk Kinase family member (mek-1) [Caenorhabditis elegans] 1.0E-154
blast AAA79746 Map kinase kinase or erk kinase protein 1, isoform a [Caenorhabditis elegans] ref|NP_001024771.1| MAP kinase kinase or Erk Kinase family member (mek-1) [Caenorhabditis elegans] 1.0E-149
blast CAE70218 Hypothetical protein CBG16698 [Caenorhabditis briggsae] 1.0E-149
blast AAP46283 Map kinase kinase or erk kinase protein 1, isoform b [Caenorhabditis elegans] ref|NP_001024772.1| MAP kinase kinase or Erk Kinase family member (mek-1) [Caenorhabditis elegans] 1.0E-149
Protein Families
Method ID Description E-Value
hanks 1.1.10 AGC group; AGC I Cyclic nucleotide regulated protein kinase (PKA & PKG); DdPK1 8.0E-18
Protein Domains
Database ID Description E-Value
Pfam IPR000719 EMBL-EBI Protein kinase 1.9E-43
Pfam IPR000719 EMBL-EBI Protein kinase 2.2E-56
Pfam IPR000719 EMBL-EBI Protein kinase 2.2E-56
Sequence
Target Sequence 
>C. ELEGANS:191720_AT
gacttctgtcaactcgtcgagagctgcctgcagcgtgatccaacgatgcgtcccaattac
gatatgctcctccagcatccgtttgtcgtgcatcacgagaaaattgaaaccgacgtcgag
gagtggtttgccgatgtgatgggcgacgattccgcgtaccacaattctaatgagatttcc
aatcttactgaccaatacgcacaaagcctccaacaacaaatacaacttttgcagattgaa
aatgcatttttaaaagaacagcaagtaaaaagagaagaaaatgaacaagagagaataaga
aatatcgaaatggaggagcaatacagagccgataagttccggcaagagcaacaagctaaa
gagtttgaagatcttcaacacagaagagaatcggtttctcagataaaccagtctaggcgt
gggacgactactcaaattttggccagaggaaatgaagtttcaataaatggggaaacttgg
tgccaacttccacctcaccacccaccgattccagctattattagcgatcgatctcagtat
tcacaacg

BLASTn GenBank NR
Probe Info
Probe Sequence(5'-3') Probe X Probe Y Probe Interrogation
Position 		Strandedness
GACTTCTGTCAACTCGTCGAGAGCT 169 371 901 Antisense
CCTGCAGCGTGATCCAACGATGCGT 295 265 927 Antisense
GCGTCCCAATTACGATATGCTCCTC 29 293 948 Antisense
TGTGATGGGCGACGATTCCGCGTAC 140 555 1035 Antisense
ATTCCGCGTACCACAATTCTAATGA 703 7 1049 Antisense
GATTTCCAATCTTACTGACCAATAC 631 427 1074 Antisense
TGACCAATACGCACAAAGCCTCCAA 653 569 1089 Antisense
GTCTAGGCGTGGGACGACTACTCAA 210 447 1311 Antisense
GGAAACTTGGTGCCAACTTCCACCT 643 525 1371 Antisense
CCCACCGATTCCAGCTATTATTAGC 472 257 1401 Antisense
GCGATCGATCTCAGTATTCACAACG 418 291 1424 Antisense
Sequence Source Affymetrix Proprietary Database