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[191716_at] Polyposis locus protein 1

Description T19C3.4 /REP_DB=WormBase Gene ID /WP=CE02055 /TR=SW:Q10010 /GB=AAC46595.1 /SUBMIT=ST.LOUIS /CHR=3 /FEA=Sanger Annotation /DEF=Polyposis locus protein 1
Cluster 6grp_highest_10_10 > 11      6grp_high1_10_10 > 01      4grp_highest_8_8 > 39      4grp_high_8_8 > 12      6grp_highest_nonorm > 80      6grp_total > 08      4grp_total > 12      6grp_high1_sub > De      6grp_total_sub > Decrease      

Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 271
1 2 3 4 range
A 243.4
(-0.6)
P 		191
(-1.8)
P 		134.7
(-3)
P 		406.1
(3)
P 		271
B 209
(-1.7)
P 		191
(-2.3)
P 		168.4
(-3)
P 		352.1
(3)
P 		184
C 275.9
(-0.5)
P 		202.6
(-2.5)
P 		185.5
(-3)
P 		403.7
(3)
P 		218
avr 242.8
(-0.9) 		194.9
(-2.1) 		162.9
(-3) 		387.3
(3) 		224

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 281
1 2 3 4 5 6 range
A 283
(3)
P 		261.7
(2)
P 		253.6
(1.6)
P 		189.5
(-1.5)
P 		157.7
(-3)
P 		202.8
(-0.8)
P 		125
B 239.1
(1.8)
P 		210.2
(0.5)
P 		264.5
(3)
P 		253.6
(2.5)
P 		133.3
(-3)
P 		180.7
(-0.8)
P 		131
C 414.1
(3)
P 		227.7
(-2)
P 		205.3
(-2.5)
P 		249.1
(-1.4)
P 		246.9
(-1.4)
P 		188.3
(-3)
P 		226
avr 312.1
(3) 		233.2
(-0.6) 		241.1
(-0.2) 		230.7
(-0.7) 		179.3
(-3) 		190.6
(-2.5) 		133
No Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 56
1 2 3 4 range
A 88.6
(3)
P 		41.5
(-2.3)
P 		35.2
(-3)
P 		59.4
(-0.3)
P 		53
B 66.6
(1.6)
P 		47.2
(-1.6)
P 		39
(-3)
P 		75
(3)
P 		36
C 91.3
(3)
P 		58.3
(-3)
P 		64.6
(-1.9)
P 		68.1
(-1.2)
P 		33
avr 82.2
(3) 		49
(-2.5) 		46.3
(-3) 		67.5
(0.5) 		36

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 106
1 2 3 4 5 6 range
A 52.2
(-2.4)
P 		93.1
(3)
P 		55.2
(-2)
P 		48.1
(-2.9)
P 		47.6
(-3)
P 		49.4
(-2.8)
P 		46
B 83.2
(3)
P 		70
(0.3)
P 		64.2
(-0.9)
P 		67.2
(-0.3)
P 		54.2
(-3)
P 		67.4
(-0.3)
P 		29
C 153.5
(3)
P 		69.5
(-1.9)
P 		52.2
(-2.9)
P 		50.1
(-3)
P 		79.9
(-1.3)
P 		63
(-2.3)
P 		103
avr 96.3
(3) 		77.5
(0.3) 		57.2
(-2.7) 		55.1
(-3) 		60.6
(-2.2) 		59.9
(-2.3) 		41
NetAffx Links Cluster Members
Consensus/Exemplar
GeneChip Array Information
Probe Set ID 191716_at
GeneChip Array C. elegans Genome Array
Organism Common Name Nematode
Probe Design Information
Transcript ID(Array Design) affy.Ce.8285
Sequence Type Exemplar sequence
Representative Public ID T19C3.4 NCBI
Target Description T19C3.4 /REP_DB=WormBase Gene ID /WP=CE02055 /TR=SW:Q10010 /GB=AAC46595.1 /SUBMIT=ST.LOUIS /CHR=3 /FEA=Sanger Annotation /DEF=Polyposis locus protein 1
Cluster Evidence This cluster is supported by a Sanger Annotation.
Annotation Method Description
Annotation Description This probe set was annotated using the Matching Probes based pipeline to a RefSeq identifier using 1 transcript(s).
Annotation Grade This is a grade A annotation.
Annotation Transcript Cluster (# of Matching Probes) NM_064820(11)
Transcript Assignments
Representative
Transcript		 Description Matching Probes Related Probesets by Grade
NM_064820 NCBI Caenorhabditis elegans T19C3.4 (T19C3.4) mRNA, complete cds. 11/11 None
GENEFINDER00000033756 ENSEMBL cdna:GeneFinder chromosome:CEL140:III:618777:620209:-1 11/11 None
T19C3.4 ENSEMBL cdna:known chromosome:CEL140:III:618243:620209:-1 gene:T19C3.4 11/11 None
Annotation Notes
Cross Hybridizing mRNA Matched Probes Nature of Assignment Related Probesets by Grade
SNAP00000033749 7/11 Cross Hyb Matching Probes None
Genomic Alignment of Consensus/Exemplar Sequence
Assembly Wormbase March 2004
Alignment(s)
Position Identity Coverage Cytoband
chrIII:618776-620209(-) 100.0 100.0
Public Domain and Genome References
Gene Title Polyposis locus protein 1
Ensembl T19C3.4
Entrez Gene 175216 Entrez gene
SwissProt Q10010 EMBL-EBI
WormBase CE02055 Wormbase
Functional Annotations
Ortholog
ID Title Organism
DROSOPHILA_2:1632278_S_AT dm
CHICKEN:GGAAFFX.11131.1.S1_AT similar to chromosome 5 open reading frame 19; SGC32445 protein gga
HG-U133_PLUS_2:205331_S_AT chromosome 5 open reading frame 19 hs
HG-U133A_2:205331_S_AT chromosome 5 open reading frame 19 hs
HG-U133A:205331_S_AT chromosome 5 open reading frame 19 hs
HU35KSUBA:RC_AA621624_AT chromosome 5 open reading frame 19 hs
U133_X3P:G7706140_3P_S_AT chromosome 5 open reading frame 19 hs
HG-U95AV2:39619_AT chromosome 5 open reading frame 19 hs
MOE430A:1424386_AT cDNA sequence BC020184 mm
MOUSE430A_2:1424386_AT cDNA sequence BC020184 mm
MOUSE430_2:1424386_AT cDNA sequence BC020184 mm
MG-U74BV2:109998_AT cDNA sequence BC020184 mm
MU19KSUBB:TC27539_AT CDNA sequence BC020184 (BC020184), mRNA mm
Protein Similarities
Method ID Description E-Value
blast AAC46595 Hypothetical protein T19C3.4 [Caenorhabditis elegans] ref|NP_497221.1| T19C3.4 [Caenorhabditis elegans] sp|Q10010|YSV4_CAEEL Hypothetical protein T19C3.4 in chromosome III 1.0E-116
blast CAE69225 Hypothetical protein CBG15265 [Caenorhabditis briggsae] 2.0E-96
blast BAD97331.1 receptor expression enhancing protein 2 variant [Homo sapiens] 1.0E-44
Protein Domains
Database ID Description E-Value
Pfam IPR004345 EMBL-EBI TB2/DP1 and HVA22 related protein 5.5E-45
Trans Membrane
ID Number Of Domains Domain Boundaries
NP_497221.1 2 37-54,58-80
T19C3.4 2 37-54,58-80
GENEFINDER00000033756 2 37-54,58-80
Sequence
Target Sequence 
>C. ELEGANS:191716_AT
gatttagtcttagccttctggttcccgttctatttccagttgaagattgtcttcattttt
tggctgctaagtccatggacgaaaggagcatctattttgtacagaaaatgggtccaccca
acactcaacagacacgagaaggacattgacgcgctgctggaatcggcaaaatcagaatcg
tataatcagttaatgcgaatcggaagtaaaagcctggtatatgcaaaggatgtggtggca
gaagctgcagttcggggacagcagcagttagtgaatcagcttcaaagatcctacagtgct
aacgatgttggctcagaacgtgaagctctcacgaaaaacattaacattgtgaaaatcgag
gagctggacgagaacagtgacacagatctccaaaaatcgccccgcccacgtcgtcgagct
tcttcgagatctcgttcaagatcaaggactatcgatagtggagctgatagtgaatttaca
actgctgctacaattcca

BLASTn GenBank NR
Probe Info
Probe Sequence(5'-3') Probe X Probe Y Probe Interrogation
Position 		Strandedness
GATTTAGTCTTAGCCTTCTGGTTCC 13 427 175 Antisense
TTCCCGTTCTATTTCCAGTTGAAGA 133 699 196 Antisense
ATTGTCTTCATTTTTTGGCTGCTAA 254 5 220 Antisense
GAAAATGGGTCCACCCAACACTCAA 575 319 278 Antisense
CGAGAAGGACATTGACGCGCTGCTG 292 249 309 Antisense
TTGACGCGCTGCTGGAATCGGCAAA 190 703 320 Antisense
TGGCAGAAGCTGCAGTTCGGGGACA 11 547 410 Antisense
GTTGGCTCAGAACGTGAAGCTCTCA 479 435 481 Antisense
GACACAGATCTCCAAAAATCGCCCC 693 365 553 Antisense
ACGTCGTCGAGCTTCTTCGAGATCT 449 93 582 Antisense
ATTTACAACTGCTGCTACAATTCCA 703 13 648 Antisense
Sequence Source Affymetrix Proprietary Database